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Elliott Sohn, MD, FASRS, FARVO

Professor of Ophthalmology and Visual Sciences

Introduction

Elliott H Sohn, MD, FASRS, FARVO is the Endowed Chair of Diabetic Retinopathy Research and Professor of Ophthalmology and Visual Sciences at the University of Iowa. His translational research centers on the use of artificial intelligence, genetics and immunology to study neovascular ‘wet’ age-related macular degeneration, diabetic retinal disease (particularly neuronal degeneration) and inherited retinal diseases. His surgical expertise is in complex macular holes, epiretinal membranes and retinal detachments. He is a key opinion leader in gene and stem cell therapies, having served as an investigator for numerous gene therapy trials in humans, and develops novel instruments for scaffold-based photoreceptor cell restoration treatment. He was a co-investigator and surgeon for the first FDA approved gene therapy in humans, voretigene neparvovec (Luxturna) for biallelic RPE65 gene mutation causing childhood onset inherited blindness. His collaborative research has been continuously funded by the National Institute of Health (NIH), for whom he regularly serves as grant reviewer.

He serves on the ACGME Residency Review Committee for Ophthalmology, is the American Board of Ophthalmology liaison to the Macula Society, and committees for Retina Society, American Society of Retina Specialists, and the Asia Pacific Academy of Ophthalmology. He is the recipient of numerous awards, including the Macula Society’s Young Investigator Award. He has served as Chair of the Association for Research in Vision and Ophthalmology Retina section of the Annual Meeting Program Committee, Vice Chair for the ACGME RC for Ophthalmology, the University of Iowa Physicians Board as member-at-large, committee member of the American Academy of Ophthalmology, and Director of Retina Fellowships at the University of Iowa.

He has written or co-authored over 100 peer-reviewed manuscripts and 10 book chapters. He is on the editorial board of Nature Scientific Reports and the Asia-Pacific Journal of Ophthalmology.

Current Positions

  • Endowed Chair in Diabetic Retinopathy Research
  • Professor of Ophthalmology and Visual Sciences

Education

  • BA in Chemistry, Williams College, Williamstown, MA
  • MD, University of Washington School of Medicine, Seattle, WA
  • Internship in Internal Medicine, University of Washington, Seattle, WA
  • Resident in Ophthalmology, University of Washington, Seattle, WA
  • Fellow in Medical Retina, Moorfields Eye Hospital, London, England
  • Fellow in Vitreoretinal Surgery, Doheny Eye Institute/University of Southern California, Los Angeles, CA

Center, Program and Institute Affiliations

Research Interests

  • Genetics and immune based mechanisms and treatments of age-related macular degeneration
  • Diabetic retinopathy
  • Artificial intelligence-based OCT image analysis
  • Novel retinal surgical therapies and techniques
  • Gene and stem cell-based translational research
  • Rural and underserved healthcare disparities

Licenses & Certifications

  • State of Iowa Medical License, Iowa Board of Medicine, IA
  • ABO Certification, American Board of Ophthalmology
  • NBME Diplomate, National Board of Medical Examiners
  • State of California Medical License
  • General Medical Council, United Kingdom
  • State of Washington Medical License, Washington State Department of Medicine

Selected Publications

  • Linton EF, Ahmad NU, Filister R, Wang JK, Sohn EH, Kardon R. (2025). Laser speckle flowgraphy reveals widespread reductions in ocular blood flow in non-exudative age-related macular degeneration. Am J Ophthalmol 273:92-106.. DOI: 10.1016/j.ajo.2025.01.012. PMID: 39892803.
  • Park JG, Adrean SD, Begaj T, Capone A Jr, Charles S, Chen SN, Chou HD, Cohen MN, Corona ST, Faia LJ, Garg SJ, Garretson BR, Gregori NZ, Haller JA, Houghton OM, Hsu J, Jo J, Kaiser RS, Lai CC, Mahgoub MM, Mansoor M, Matoba R, Morizane Y, Nehemy MB, Raphaelian PV, Regillo CD, Ruby AJ, Runner MM, Sneed SR, Sohn EH, Spirn MJ, Vander JF, Wakabayashi T, Wolfe JD, Wykoff CC, Yonekawa Y, Yoon YH, Mahmoud TH. (2024). Surgical Management of Full-Thickness Macular Holes in Macular Telangiectasia Type 2: A Global Multicenter Study. Ophthalmology 131(1):66-77. DOI: 10.1016/j.ophtha.2023.08.025. PMID: 37661066.
  • Tang Z, Yang D, Nguyen TX, Zhang S, Fang D, Chan VTT, Tham CC, Sohn EH, Tsang KK, Wong CYK, Hui VWK, Yu AHY, Lam JTW, Chan CKM, Lai TYY, Szeto SKH, Cheung CY. (2025). Relationship of OCT-Based Diabetic Retinal Neurodegeneration to the Development and Progression of Diabetic Retinopathy: A Cohort Study. Invest Ophthalmol Vis Sci 66(2):32. DOI: 10.1167/iovs.66.2.32. PMID: 39932471. PMCID: PMC11817850.
  • Amram AL, Whitmore SS, Wang C, Clavell C, Lyons LJ, Rusakevich AM, Han I, Folk J, Boldt HC, Stone EM, Russell SR, Lee K, Abramoff M, Wykoff C, Sohn EH. (2025). Progressive inner retinal neurodegeneration in non-proliferative macular telangiectasia type 2. Br J Ophthalmol 109(3):401-407. DOI: 10.1136/bjo-2023-325115. PMID: 39288977.
  • Gibson-Corley KN, Thompson JR, Worthington KS, Kaalberg EE, Mullins RF, Stone EM, Han IC, Sohn EH, Tucker BA. (2018). Human Retinal Engineering using 3D PCL Scaffolds. FASEB Journal 32(1).
  • Burnight ER, Fenner BJ, Han IC, DeLuca AP, Whitmore SS, Bohrer LR, Andorf JL, Sohn EH, Mullins RF, Tucker BA, Stone EM. (2024). Demonstration of the pathogenicity of a common non-exomic mutation in ABCA4 using iPSC-derived retinal organoids and retrospective clinical data. Hum Mol Genet 33(16):1379-1390. DOI: 10.1093/hmg/ddad176. PMID: 37930186. PMCID: PMC11305681.
  • Jamshidi F, Lozano L, Tucker B, Andorf J, Sohn EH, Stone E, Groves A, Zakharia Y, Boldt HC, Binkley E. (2024). Belzutifan in Individuals with von Hippel-Lindau Retinal Hemangioblastomas: Institutional Experience and Review of the Literature. Ocul Oncol Pathol 10(3):154-161. DOI: 10.1159/000539434. PMID: 39224523. PMCID: PMC11368390.
  • Han IC, Mullins RF, Stone EM, Sohn EH. (2022). Macular dystrophies. In: Ryan’s Retina, 7th edition. Eds: Sadda SR, Schachat AP, Wilkinson CP, Hinton DR, Wiedemann P, Freund KB, Sarraf D. Edinburgh: Elsevier; pp 879-926. 
  • Troyer J, Sohn EH. (2022). Macular Neovascularization in Boy. Equipment: Topcon TRC 50DX. Wide Angle. University of Iowa Hospitals and Clinics, Iowa City, IA. Cover article and second place winner in the Wide Angle category at the Ophthalmic Photographers’ Society 2022 Scientific Exhibition. 
  • Ricca AM, Sohn EH, Abramoff MD. (2016). New thinking on diabetes and the retina. Retina Specialist.