Michael D. Abramoff, MD, PhD

Portrait
The Robert C. Watzke, MD, Professor of Retina Research
Professor of Ophthalmology and Visual Sciences
Professor of Electrical and Computer Engineering (ECE)
Professor of Biomedical Engineering (BME)

Contact Information

Primary Office: 11205 PFP
Iowa City, IA 52242
319-384-5833

Education

MS, Medicine, University of Amsterdam
MS, Biomedical Informatics, University of Amsterdam
MD, Medicine, University of Amsterdam
PhD, Biomedical Imaging, University of Utrecht
Clinical Epidemiology, Vrije Universiteit

Post Doctoral Fellow, Research Fellowship, RIKEN Neural Networks Research Laboratory
Resident, Surgery, University Hospital of Maastricht
Resident, Ophthalmology, University Hospital of Utrecht
Fellow, Medical Retina, Vrije Universiteit University Hospital
Fellow, Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics

Licensure and Certifications

State of Iowa Medical License - Iowa Board of Medicine
Netherlands Ophthalmology Certification - Netherlands Ophthalmologic Society (Netherlands Board of Ophthalmology)
USMLE I and II, ECFMG certification
Medical License, Netherlands

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Translational Biomedicine, Medical Scientist Training Program

Center, Program and Institute Affiliations

Carver Family Center for Macular Degeneration, Fraternal Order of Eagles Diabetes Research Center, Institute for Vision Research, Iowa Institute for Biomedical Imaging

Publications

Abramoff, M. D., Fort, P. E., Han, I. C., Jayasundera, K. T., Sohn, E. H. & Gardner, T. W. (2018). Approach for a Clinically Useful Comprehensive Classification of Vascular and Neural Aspects of Diabetic Retinal Disease. Investigative ophthalmology & visual science, 59(1), 519-527. PMID: 29372250.

Lee, K., Zhang, H., Wahle, A., Abràmoff, M. D. & Sonka, M. (2018). Multi-layer 3D simultaneous retinal OCT layer segmentation: Just-enough interaction for routine clinical use. In Lecture Notes in Computational Vision and Biomechanics. pp. 862-871. DOI: 10.1007/978-3-319-68195-5_94.

Abràmoff, M. D. (2018). Image Processing. In A. P. Schachat , C. P. Wilkinson , D. R. Hinton , S. R. Sadda , P. Wiedemann (Eds.) Ryan's Retina. (6th ed), pp. 196-223. London; Philadelphia: Elsevier.

van der Heijden, A. A., Abramoff, M. D., Verbraak, F., van Hecke, M. V., Liem, A. & Nijpels, G. (2018). Validation of automated screening for referable diabetic retinopathy with the IDx-DR device in the Hoorn Diabetes Care System. Acta ophthalmologica, 96(1), 63-68. PMID: 29178249.

Costa, P., Galdran, A., Meyer, M. I., Niemeijer, M., Abramoff, M., Mendonca, A. M. & Campilho, A. (In Press). End-to-end Adversarial Retinal Image Synthesis. IEEE transactions on medical imaging. PMID: 28981409.

Lynch, S. K., Abràmoff, M. D. (2017). Diabetic retinopathy is a neurodegenerative disorder. Vision research, 139, 101-107. PMID: 28408138.

Zhang, Y., Chioreso, C., Schweizer, M. L. & Abràmoff, M. D. (2017). Effects of Aflibercept for Neovascular Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis of Observational Comparative Studies. Investigative ophthalmology & visual science, 58(13), 5616-5627. PMID: 29094167.

Klimscha, S., Waldstein, S. M., Schlegl, T., Bogunovic, H., Sadeghipour, A., Philip, A. M., Podkowinski, D., Pablik, E., Zhang, L., Abramoff, M. D., Sonka, M., Gerendas, B. S. & Schmidt-Erfurth, U. (2017). Spatial Correspondence Between Intraretinal Fluid, Subretinal Fluid, and Pigment Epithelial Detachment in Neovascular Age-Related Macular Degeneration. Investigative ophthalmology & visual science, 58(10), 4039-4048. PMID: 28813577.

Lee, S. Y., Cheng, J. l., Gehrs, K. M., Folk, J. C., Sohn, E. H., Russell, S. R., Guo, Z., Abràmoff, M. D. & Han, I. C. (2017). Choroidal Features of Acute Macular Neuroretinopathy via Optical Coherence Tomography Angiography and Correlation With Serial Multimodal Imaging. JAMA Ophthalmology, 135(11), 1177-1183. DOI: 10.1001/jamaophthalmol.2017.3790.

Miri, M. S., Robles, V. A., Abràmoff, M. D., Kwon, Y. H. & Garvin, M. K. (2017). Incorporation of gradient vector flow field in a multimodal graph-theoretic approach for segmenting the internal limiting membrane from glaucomatous optic nerve head-centered SD-OCT volumes. Computerized medical imaging and graphics: the official journal of the Computerized Medical Imaging Society, 55, 87-94. PMID: 27507325.

Shah, A., Abramoff, M. D. & Wu, X. (2017). Simultaneous multiple surface segmentation using deep learning. In Lecture Notes in Computer Science. (Vols. 10553 LNCS). pp. 3-11. DOI: 10.1007/978-3-319-67558-9_1.

Colaizy, T. T., Longmuir, S., Gertsch, K., Abràmoff, M. D. & Klein, J. M. (2017). Use of a Supplemental Oxygen Protocol to Suppress Progression of Retinopathy of Prematurity. Investigative ophthalmology & visual science, 58(2), 887-891. PMID: 28159975.

Klein, B. E., Johnson, C. A., Meuer, S. M., Lee, K., Wahle, A., Lee, K. E., Kulkarni, A., Sonka, M., Abràmoff, M. D. & Klein, R. (2017). Nerve Fiber Layer Thickness and Characteristics Associated with Glaucoma in Community Living Older Adults: Prelude to a Screening Trial?. Ophthalmic epidemiology, 24(2), 104-110. PMID: 28032805.

Roybal, N. C., Sledz, E., Elshatory, Y., Zhang, L., Almeida, D. R., Chin, E. K., Critser, B., Abramoff, M. D. & Russell, S. R. (In Press). Dysfunctional Autonomic Regulation of the Choroid in Central Serous Chorioretinopathy. Retina (Philadelphia, Pa.). PMID: 28489693.

Xu, X., Ding, W., Abràmoff, M. D. & Cao, R. (2017). An improved arteriovenous classification method for the early diagnostics of various diseases in retinal image. Computer methods and programs in biomedicine, 141, 3-9. PMID: 28241966.

Miri, M. S., Abràmoff, M. D., Kwon, Y. H., Sonka, M. & Garvin, M. K. (2017). A machine-learning graph-based approach for 3D segmentation of Bruch's membrane opening from glaucomatous SD-OCT volumes. Medical image analysis, 39, 206-217. PMID: 28528295.

Guo, Z., Kwon, Y. H., Lee, K., Wang, K., Wahle, A., Alward, W. L., Fingert, J. H., Bettis, D. I., Johnson, C. A., Garvin, M. K., Sonka, M. & Abràmoff, M. D. (2017). Optical Coherence Tomography Analysis Based Prediction of Humphrey 24-2 Visual Field Thresholds in Patients With Glaucoma. Investigative ophthalmology & visual science, 58(10), 3975-3985. PMID: 28796875.

Philip, A. M., Gerendas, B. S., Zhang, L., Faatz, H., Podkowinski, D., Bogunovic, H., Abramoff, M. D., Hagmann, M., Leitner, R., Simader, C., Sonka, M., Waldstein, S. M. & Schmidt-Erfurth, U. (2016). Choroidal thickness maps from spectral domain and swept source optical coherence tomography: algorithmic versus ground truth annotation. The British journal of ophthalmology, 100(10), 1372-1376. PMID: 26769670.

Miri, M. S., Abràmoff, M. D., Kwon, Y. H. & Garvin, M. K. (2016). Multimodal registration of SD-OCT volumes and fundus photographs using histograms of oriented gradients. Biomedical optics express, 7(12), 5252-5267. PMID: 28018740.

Blokhuis, C., Demirkaya, N., Cohen, S., Wit, F. W., Scherpbier, H. J., Reiss, P., Abramoff, M. D., Caan, M. W., Majoie, C. B., Verbraak, F. D. & Pajkrt, D. (2016). The Eye as a Window to the Brain: Neuroretinal Thickness Is Associated With Microstructural White Matter Injury in HIV-Infected Children. Investigative ophthalmology & visual science, 57(8), 3864-3871. PMID: 27447087.

Abràmoff, M. D., Lou, Y., Erginay, A., Clarida, W., Amelon, R., Folk, J. C. & Niemeijer, M. (2016). Improved Automated Detection of Diabetic Retinopathy on a Publicly Available Dataset Through Integration of Deep Learning. Investigative ophthalmology & visual science, 57(13), 5200-5206. PMID: 27701631.

Sonka, M., Abràmoff, M. D. (2016). Quantitative analysis of retinal OCT. Medical image analysis, 33, 165-169. PMID: 27503080.

Oguz, I., Abramoff, M. D., Zhang, L., Lee, K., Zhang, E. Z. & Sonka, M. (2016). 4D Graph-Based Segmentation for Reproducible and Sensitive Choroid Quantification From Longitudinal OCT Scans. Investigative ophthalmology & visual science, 57(9), OCT621-OCT630. PMID: 27936264.

Nava, D. R., Antony, B., Zhang, L. I., Abràmoff, M. D. & Wildsoet, C. F. (2016). Novel method using 3-dimensional segmentation in spectral domain-optical coherence tomography imaging in the chick reveals defocus-induced regional and time-sensitive asymmetries in the choroidal thickness. Visual neuroscience, 33, E010. PMID: 27485367.

Choi, C. S., Zhang, L., Abràmoff, M. D., Sonka, M., Shifera, A. S. & Kay, C. N. (2016). Evaluating Efficacy of Aflibercept in Refractory Exudative Age-Related Macular Degeneration With OCT Segmentation Volumetric Analysis. Ophthalmic surgery, lasers & imaging retina, 47(3), 245-51. PMID: 26985798.

Lee, K., Buitendijk, G. H., Bogunovic, H., Springelkamp, H., Hofman, A., Wahle, A., Sonka, M., Vingerling, J. R., Klaver, C. C. & Abràmoff, M. D. (2016). Automated Segmentability Index for Layer Segmentation of Macular SD-OCT Images. Translational vision science & technology, 5(2), 14. PMID: 27066311.

Zarei, K., Scheetz, T. E., Christopher, M., Miller, K., Hedberg-Buenz, A., Tandon, A., Anderson, M. G., Fingert, J. H. & Abràmoff, M. D. (2016). Automated Axon Counting in Rodent Optic Nerve Sections with AxonJ. Scientific reports, 6, 26559. PMID: 27226405.

Sohn, E. H., van Dijk, H. W., Jiao, C., Kok, P. H., Jeong, W., Demirkaya, N., Garmager, A., Wit, F., Kucukevcilioglu, M., van Velthoven, M. E., DeVries, J. H., Mullins, R. F., Kuehn, M. H., Schlingemann, R. O., Sonka, M., Verbraak, F. D. & Abramoff, M. D. (2016). Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus. Proceedings of the National Academy of Sciences USA, 113(19), E2655-E64. PMID: 27114552.

Zarei, K., Scheetz, T. E., Christopher, M., Miller, K., Hedberg-Buenz, A., Tandon, A., Anderson, M. G., Fingert, J. H. & Abràmoff, M. D. (2016). Corrigendum: Automated Axon Counting in Rodent Optic Nerve Sections with AxonJ. Scientific reports, 6, 34124. PMID: 27759018.

Hedberg-Buenz, A., Christopher, M. A., Lewis, C. J., Fernandes, K. A., Dutca, L. M., Wang, K., Scheetz, T. E., Abràmoff, M. D., Libby, R. T., Garvin, M. K. & Anderson, M. G. (2016). Quantitative measurement of retinal ganglion cell populations via histology-based random forest classification. Experimental eye research, 146, 370-385. PMID: 26474494.

Demirkaya, N., Wit, F. W., van Den Berg, T. J., Kooij, K. W., Prins, M., Schlingemann, R. O., Abramoff, M. D., Reiss, P. & Verbraak, F. D. (2016). HIV-Associated Neuroretinal Disorder in Patients With Well-Suppressed HIV-Infection: A Comparative Cohort Study. Investigative ophthalmology & visual science, 57(3), 1388-97. PMID: 27018841.

Hedberg-Buenz, A., Christopher, M. A., Lewis, C. J., Meyer, K. J., Rudd, D. S., Dutca, L. M., Wang, K., Garvin, M. K., Scheetz, T. E., Abràmoff, M. D., Harper, M. M. & Anderson, M. G. (2016). RetFM-J, an ImageJ-based module for automated counting and quantifying features of nuclei in retinal whole-mounts. Experimental eye research, 146, 386-392. PMID: 26283021.

Miri, M. S., Robles, V. A., Abràmoff, M. D., Kwon, Y. H. & Garvin, M. K. (2015). Multimodal graph-theoretic approach for segmentation of the internal limiting membrane at the optic nerve head. Munich, Germany: Proceedings - 2nd International Workshop on Ophthalmic Medical Image Analysis of MICCAI (Medical Image Computing and Computer Assisted Intervention).

Bogunovic, H., Abràmoff, M. D. & Sonka, M. (2015). Geodesic Graph Cut based Retinal Fluid Segmentation in Optical Coherence Tomography. pp. 49-56. n.p.: Proceedings of the Ophthalmic Medical Image Analysis Second International Workshop, OMIA 2015, Held in Conjunction with MICCAI 2015, Munich, Germany, October 9, 2015..

Kafieh, R., Rabbani, H., Hajizadeh, F., Abramoff, M. D. & Sonka, M. (2015). Thickness mapping of eleven retinal layers segmented using the diffusion maps method in normal eyes. Journal of ophthalmology, 2015, 259123. PMID: 25960888.

Deng, W., Antony, B., Sohn, E. H., Abràmoff, M. D. & Garvin, M. K. (2015). Segmentation of the Retinal Vasculature within Spectral-Domain Optical Coherence Tomography Volumes of Mice. In X. Chen , M. K. Garvin , J. Liu , E. Trucco & Y. Xu , X. Chen , M. K. Garvin , J. Liu , E. Trucco , Y. Xu (Eds.) Proceedings of the Ophthalmic Medical Image Analysis Second International Workshop (OMIA 2015). pp. 65-72. Iowa City, Iowa: Iowa Research Online.

Hu, Q., Abràmoff, M. D. & Garvin, M. K. (2015). Automated construction of arterial and venous trees in retinal images. Journal of medical imaging, 2(4), 044001. PMID: 26636114.

Abràmoff, M. D., Niemeijer, M. (2015). Mass screening of diabetic retinopathy using automated methods. In G. Michelson , G. Michelson (Eds.) Teleophthalmology in preventive medicine. pp. 41-50. Berlin; Heidelberg: Springer-Verlag.

Lee, K., Zhang, L., Abramoff, M. D. & Sonka, M. (2015). Fast and memory-efficient LOGISMOS graph search for intraretinal layer segmentation of 3-D macular OCT scans. In Medical Imaging 2015: Image Processing [Proceedings of SPIE, vol 9413]. pp. 94133x. Bellingham, Washington: SPIE. DOI: 10.1117/12.2082135.

Xu, X. b., Lee, K., Zhang, L., Sonka, M. & Abràmoff, M. d. (2015). Stratified Sampling Voxel Classification for Segmentation of Intraretinal and Subretinal Fluid in Longitudinal Clinical OCT Data. IEEE Transactions on Medical Imaging, 34(7), 1616-1623. DOI: 10.1109/TMI.2015.2408632.

Hansen, M. B., Abràmoff, M. D., Folk, J. C., Mathenge, W., Bastawrous, A. & Peto, T. (2015). Results of Automated Retinal Image Analysis for Detection of Diabetic Retinopathy from the Nakuru Study, Kenya. PloS one, 10(10), e0139148. PMID: 26425849.

Almeida, D. R., Zhang, L., Chin, E. K., Mullins, R. F., Kucukevcilioglu, M., Critser, D. B., Sonka, M., Stone, E. M., Folk, J. C., Abràmoff, M. D. & Russell, S. R. (2015). Comparison of retinal and choriocapillaris thicknesses following sitting to supine transition in healthy individuals and patients with age-related macular degeneration. JAMA ophthalmology, 133(3), 297-303. PMID: 25521616.

Bogunovic, H., Kwon, Y. H., Rashid, A., Lee, K., Critser, D. B., Garvin, M. K., Sonka, M. & Abramoff, M. D. (2015). Relationships of retinal structure and Humphrey 24-2 visual field thresholds in patients with glaucoma. Investigative Opthalmology & Visual Science, 56(1), 259-271. PMID: 25491294.

Miri, M. S., Abramoff, M. D., Lee, K., Niemeijer, M., Wang, J. K., Kwon, Y. H. & Garvin, M. K. (2015). Multimodal Segmentation of Optic Disc and Cup From SD-OCT and Color Fundus Photographs Using a Machine-Learning Graph-Based Approach. IEEE transactions on medical imaging, 34(9), 1854-66. PMID: 25781623.

Antony, B. J., Stetson, P. F., Abramoff, M. D., Lee, K., Colijn, J. M., Buitendijk, G. H., Klaver, C. C., Roorda, A. & Lujan, B. J. (2015). Characterizing the Impact of Off-Axis Scan Acquisition on the Reproducibility of Total Retinal Thickness Measurements in SDOCT Volumes. Translational vision science & technology, 4(4), 3. PMID: 26257998.

Christopher, M., Abràmoff, M. D., Tang, L., Gordon, M. O., Kass, M. A., Budenz, D. L., Fingert, J. H. & Scheetz, T. E. (2015). Stereo Photo Measured ONH Shape Predicts Development of POAG in Subjects With Ocular Hypertension. Investigative ophthalmology & visual science, 56(8), 4470-9. PMID: 26193923.

Zhang, L., Buitendijk, G. H., Lee, K., Sonka, M., Springelkamp, H., Hofman, A., Vingerling, J. R., Mullins, R. F., Klaver, C. C. & Abràmoff, M. D. (2015). Validity of Automated Choroidal Segmentation in SS-OCT and SD-OCT. Investigative ophthalmology & visual science, 56(5), 3202-11. PMID: 26024104.

Demirkaya, N., Cohen, S., Wit, F. W., Abramoff, M. D., Schlingemann, R. O., Kuijpers, T. W., Reiss, P., Pajkrt, D. & Verbraak, F. D. (2015). Retinal Structure and Function in Perinatally HIV-Infected and cART-Treated Children: A Matched Case-Control Study. Investigative ophthalmology & visual science, 56(6), 3945-54. PMID: 26087360.

Darma, S., Kok, P. H., van den Berg, T. J., Abràmoff, M. D., Faber, D. J., Hulsman, C. A., Zantvoord, F., Mourits, M. P., Schlingemann, R. O. & Verbraak, F. D. (2015). Optical density filters modeling media opacities cause decreased SD-OCT retinal layer thickness measurements with inter- and intra-individual variation. Acta ophthalmologica, 93(4), 355-61. PMID: 25487761.

Abràmoff, M. D., Baker, M. S. (2015). New Concepts in Orbital Imaging. In Z. A. Karcioglu , Z. A. Karcioglu (Eds.) Orbital Tumors. (2nd), pp. 111-120. New York: Springer.

Helmchen, L. A., Lehmann, H. P. & Abràmoff, M. D. (2014). Automated detection of retinal disease. The American journal of managed care, 20(11 Spec No. 17), eSP48-52. PMID: 25811819.

Sohn, E. H., Khanna, A., Tucker, B. A., Abràmoff, M. D., Stone, E. M. & Mullins, R. F. (2014). Structural and biochemical analyses of choroidal thickness in human donor eyes. Invest Ophthalmol Vis Sci, 55(3), 1352-1360. PMID: 24519422.

Kanagasingam, Y., Bhuiyan, A., Abràmoff, M. D., Smith, R. T., Goldschmidt, L. & Wong, T. Y. (2014). Progress on retinal image analysis for age related macular degeneration. Progress in Retinal and Eye Research, 38, 20-42. PMID: 24211245.

Christopher, M., Tang, L., Fingert, J. H., Scheetz, T. E. & Abramoff, M. D. (2014). Automated discovery of structural features of the optic nerve head on the basis of image and genetic data. Proc SPIE, 9035, 90350S. DOI: 10.1117/12.2043798.

Antony, B. J., Jeong, W., Abràmoff, M. D., Sohn, E. H., Vance, J. & Garvin, M. K. (2014). Automated 3D segmentation of intraretinal surfaces in SD-OCT volumes in normal and diabetic mice. Translational Vision Science & Technology, 3(5), 8. PMID: 25346873.

Abràmoff, M. D., Mullins, R. F. & Stone, E. M. (2014). Outer segment length in different best disease genotypes. JAMA Ophthalmology, 132(9), 1152-1153. PMID: 25210991.

Zhang, L., Sonka, M., Folk, J. C., Russell, S. R. & Abràmoff, M. D. (2014). Quantifying Disrupted Outer Retinal-Subretinal Layer in SD-OCT Images in Choroidal Neovascularization. Invest Ophthalmol Vis Sci, 55(4), 2329-2335. PMID: 24569576.

Antony, B. J., Song, Q., Abràmoff, M. D., Sohn, E., Wu, W. & Garvin, M. K. (2014). Incorporation of learned shape priors into a graph-theoretic approach with application to the 3D segmentation of intraretinal surfaces in SD-OCT volumes of mice. Proceedings of SPIE, 9038, 90380D.

Quellec, G., Abràmoff, M. D. (2014). Estimating maximal measurable performance for automated decision systems from the characteristics of the reference standard. Application to diabetic retinopathy screening. PMID: 25569920.

Gerendas, B. S., Waldstein, S. M., Simader, C., Deak, G., Hajnajeeb, B., Zhang, L., Bogunovic, H., Abràmoff, M. D., Kundi, M., Sonka, M. & Schmidt-Erfurth, U. (2014). Three-dimensional automated choroidal volume assessment on standard spectral-domain optical coherence tomography and correlation with the level of diabetic macular edema. Am J Ophthalmol, 158(5), 1039-1048. PMID: 25127697.

Bogunovic, H., Sonka, M., Kwon, Y. H., Kemp, P., Abràmoff, M. D. & Wu, X. (2014). Multi-surface and multi-field co-segmentation of 3-D retinal optical coherence tomography. IEEE Trans Med Imaging, 33(12), 2242-2253. PMID: 25020067.

Springelkamp, H., Lee, K., Wolfs, R. C., Buitendijk, G. H., Ramdas, W. D., Hofman, A., Vingerling, J. R., Klaver, C. C., Abramoff, M. D. & Jansonius, N. M. (2014). Population-based evaluation of retinal nerve fiber layer, retinal ganglion cell layer, and inner plexiform layer as a diagnostic tool for glaucoma. Invest Ophthalmol Vis Sci, 55(12), 8428-8438. PMID: 25414193.

Abràmoff, M. D., Wu, X., Lee, K. & Tang, L. (2014). Subvoxel Accurate Graph Search Using Non-Euclidean Graph Space. PLOS One, 9(10), e107763. PMID: 25314272.

Antony, B., Miri, M. S., Abràmoff, M. D., Kwon, Y. H. & Garvin, M. (2014). Automated 3D segmentation of multiple surfaces with a shared hole: Segmentation of the neural canal opening in SD-OCT volumes. Med Image Comput Comput Assist Interv, 17(Pt. 1), 739-746. PMID: 25333185.

Longmuir, S. Q., Oral, R., Walz, A. E., Kemp, P. S., Ryba, J., Zimmerman, M. & Abràmoff, M. D. (2014). Quantitative measurement of retinal hemorrhages in suspected victims of child abuse. Journal of AAPOS, 18(6), 529-533. PMID: 25456029.

Kafieh, R., Rabbani, H., Abràmoff, M. D. & Sonka, M. (2013). Intra-retinal layer segmentation of 3D optical coherence tomography using coarse grained diffusion map. Med Image Anal, 17(8), 907-928. DOI: 10.1016/j.media.2013.05.006.

Abràmoff, M. D., Mullins, R. F., Lee, K., Hoffmann, J. M., Sonka, M., Critser, D. B., Stasheff, S. F. & Stone, E. M. (2013). Human photoreceptor outer segments shorten during light adaptation. Invest Ophthalmol Vis Sci, 54(5), 3721-3728. PMID: 23633665.

Abràmoff, M. D., Kay, C. N. (2013). Image Processing. In Retina, Vol. 1, Retinal Imaging and Diagnostics. (5th ed.), pp. 151-176. London: Saunders Elsevier.

Demirkaya, N., van Schuppen, S. M., Abràmoff, M. D., Garvin, M. K., Sonka, M., Schlingemann, R. O. & Verbraak, F. D. (2013). Effect of age on individual retinal layer thickness in normal eyes as measured with spectral-domain optical coherence tomography. Invest Ophthalmol Vis Sci, 54(7), 4934-4940. PMID: 23761080.

Miri, M. S., Lee, K., Niemeijer, M., Abràmoff, M. D., Kwon, Y. H. & Garvin, M. K. (2013). Multimodal segmentation of optic disc and cup from stereo fundus and SD-OCT images. Proceedings SPIE Medical Imaging 2013: Image Proccessing (Progress in Biomedical Optics and Imaging), 8669. DOI: 10.1117/12.2007010.

Trucco, E., Ruggeri, A., Karnowski, T., Giancardo, L., Chaum, E., Hubschman, J. P., al-Diri, B., Cheung, C. Y., Wong, D., Abràmoff, M. D., Lim, G., Kumar, D., Burlina, P., Bressler, N. M., Jelinek, H. F., Meriaudeau, F., Quellec, G., MacGillivray, T. & Bhillion, B. (2013). Validating retinal fundus image analysis algorithms: Issues and a proposal. Invest Ophthalmol Vis Sci, 54(5), 3546-3559. PMID: 23794433.

Rabbani, H., Sonka, M. & Abràmoff, M. D. (2013). Optical Coherence Tomography noise reduction using anisotropic local bivariate Gaussian mixture prior in 3-D complex wavelet domain. International Journal of Biomedical Imaging, 2013, article ID 417491 (23 pages). PMID: 24222760.

Kafieh, R., Rabbani, H., Abràmoff, M. D. & Sonka, M. (2013). Curvature of retinal OCTs using graph-based geometry detection. Phys Bed Biol, 58(9), 2925-2938. PMID: 23574790.

Sohn, E. H., Chen, J. J., Lee, K., Niemeijer, M., Sonka, M. & Abràmoff, M. D. (2013). Reproducibility of diabetic macular edema estimates from SD-OCT is affected by the choice of image analysis algorithm. Invest Ophthalmol Vis Sci, 54(6), 4184-4188. PMID: 23696607.

Garvin, M. K., Lee, K., Bruns, T. L., Abràmoff, M. D., Sonka, M. & Kwon, Y. H. (2013). Reproducibility of SD-OCT-based ganglion-cell-layer thickness in glaucoma using two different segmentation algorithms. Invest Ophthalmol Vis Sci, 54(10), 6998-7004. PMID: 24045993.

Christopher, M., Scheetz, T. E., Mullins, R. F. & Abràmoff, M. D. (2013). Selection of phototransduction genes in Homo sapiens. Invest Ophthalmol Vis Sci, 54(8), 5489-5496. PMID: 23868983.

Van Dijk, H. W., Verbraak, F. D., Kolk, P., Oberstein, S., Schlingemann, R. O., Russell, S. R. & Abràmoff, M. D. (2013). Variability in photocoagulation treatment of diabetic macular oedema. Acta Ophthalmologica, 91(8), 722-727. PMID: 22973860.

Hu, Q., Abràmoff, M. D. & Garvin, M. K. (2013). Automated separation of binary overlapping trees in low-contrast color retinal images. [Epub 2014/03/01]. Medical image computing and computer-assisted intervention : MICCAI International Conference on Medical Image Computing and Computer-Assisted Intervention, 16(pt 2), 436-443. PMID: 24579170.

Abràmoff, M. D., Folk, J. C., Han, D. P., Walker, J. D., Williams, D. F., Russell, S. R., Massin, P., Cochener, B., Gain, P., Tang, L., Lamard, M., Moga, D. C., Quellec, G. & Niemeijer, M. (2013). Automated analysis of retinal images for detection of referable diabetic retinopathy. JAMA Ophthalmol, 131(3), 351-7. PMID: 23494039.

Wahle, A., Lee, K., Harding, A. T., Garvin, M. K., Niemeijer, M., Sonka, M. & Abràmoff, M. D. (2013). Extending the XNAT archive tool for image and analysis management in ophthalmology research. Proc SPIE Med Imag, 8674, 86740M.

Christopher, M., Tang, L., Fingert, J. H., Scheetz, T. E. & Abràmoff, M. D. (2013). Changes in quantitative 3D shape features of the optic nerve head associated with age. Proceedinsg SPIE Medical Imaging 2013: Computer-Aided Diagnosis, 8670, 86700O. DOI: 10.1117/12.2006908..

Tang, L., Niemeijer, M., Reinhardy, J. M., Garvin, M. K. & Abràmoff, M. D. (2013). Splat feature classification with application to retinal hemorrhage detection in fundus images. IEEE Trans Med Imaging, 32(2), 364-75. PMID: 23193310.

Kafieh, R., Danesh, H., Rabbani, H., Abràmoff, M. D. & Sonka, M. (2013). Vessel segmentation in images of optical coherence tomography using shadow information and thickening of Retinal Nerve Fiber Layer. Proceedings: 38th IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2013, May 26, 2013 - May 31, 2013, Vancouver, BC, Canada, 1075-9. DOI: 10.1109/ICASSP.2013.6637815..

Antony, B. J., Abràmoff, M. D., Harper, M. M., Jeong, W., Sohn, E. H., Kwon, Y. H., Kardon, R. & Garvin, M. K. (2013). A combined machine-learning and graph-based framework for the segmentation of retinal surfaces in SD-OCT volumes. Biomedical optics express, 4(12), 2712-28. PMID: 24409375.

Joshi, V., Reinhardt, J., Garvin, M. & Abràmoff, M. D. (2013). Automated method for identification and artery-venous classification of vessel trees in retinal vessel networks. PLoS One, 9(2), e88061. PMID: 24533066.

Lee, K., Sonka, M., Kwon, Y. H., Garvin, M. K. & Abràmoff, M. D. (2013). Adjustment of the retinal angle in SD-OCT of glaucomatous eyes provides better inter-visit reproducibility of peripapillary RNFL thickness. Invest Ophthalmol Vis Sci, 54(7), 4808-4812. PMID: 23788372.

Hu, Q., Garvin, M., Christopher, M. A., Xu, X., Scheetz, T. E. & Abràmoff, M. D. (2013). Optimal Filter Approach for the Detection of Vessel Bifurcations in Color Fundus Images. Proceedings SPIE Medical Imaging 2013: Image Processing (Progress in Biomedical Optics and Imaging), 8669. DOI: 10.1117/12.2007088.

Kafieh, R., Rabbani, H., Abramoff, M. & Sonka, M. (2013). Intra-retinal layer segmentation of optical coherence tomography using diffusion map. In 2013 IEEE International Conference on Acoustics, Speech and Signal Processing. IEEE. DOI: 10.1109/icassp.2013.6637816.

Niemeijer, M., van Ginneken, B., Russell, S. R., Suttorp-Schulten, M. & Abràmoff, M. D. (2013). Automated detection and differentiation of drusen, exudates, and cotton-wool spots in digital color fundus photographs for diabetic retinopathy diagnosis. In G. J. Chader , P. L. Kaufman , D. C. Bedee , G. J. Chader & P. L. Kaufman , D. C. Bedee (Eds.) The Best of Investigative Ophthalmology and Visual Sciences: The First 50 Years 1962-2012. pp. 807-814. Rockville, MD: ARVO.

Hu, Z., Niemeijer, M., Abràmoff, M. D. & Garvin, M. K. (2012). Multimodal retinal vessel segmentation from spectral-domain optical coherence tomography and fundus photography. IEEE transactions on medical imaging, 31(10), 1900-11. PMID: 22759443.

Quellec, G., Lamard, M., Cazuguel, G., Abràmoff, M. D., Cochener, B. & Roux, C. (2012). Weakly supervised classification of medical images. Biomedical Imaging (ISBI), 2012 9th IEEE International Symposium on, 110-113.

Springelkamp, H., Lee, K., Ramdas, W. D., Vingerling, J. R., Hofman, A., Klaver, C. C., Sonka, M., Abràmoff, M. D. & Jansonius, N. M. (2012). Optimizing the information yield of 3-D OCT in glaucoma. Invest Ophthalmol Vis Sci, 53(13), 8162-71. PMID: 23154462.

Chen, X., Zhang, L., Sohn, E. H., Lee, K., Niemeijer, M., Chen, J., Sonka, M. & Abràmoff, M. D. (2012). Quantification of external limiting membrane disruption caused by diabetic macular edema from SD-OCT. Invest Ophthalmol Vis Sci, 53(13), 8042-8. PMID: 23111607.

Joshi, V. S., Maude, R. J., Reinhardt, J. M., Tang, L., Garvin, M. K., Sayeed, A. A., Ghose, A., Hassan, M. U. & Abràmoff, M. D. (2012). Automated detection of malarial retinopathy-associated retinal hemorrhages. Investigative ophthalmology & visual science, 53(10), 6582-8. PMID: 22915035.

Xu, X., Abràmoff, M. D., Bertelsen, G. & Reinhardt, J. M. (2012). Retinal vessel width measurement at branching points using an improved electric field theory-based graph approach. Proc SPIE Med Imag, 8314, 83144K.

Xu, X., Reinhardt, J. M., Hu, Q., Bakall, B., Tlucek, P. S., Bertelsen, G. & Abràmoff, M. D. (2012). Retina vessel width measurement at branchings using an improved electric field theory-based graph approach. PLoS One, 7(11), e49668. PMID: 23209588.

Zhang, L., Lee, K. M., Niemeijer, M., Mullins, R. F., Sonka, M. & Abràmoff, M. D. (2012). Automated segmentation of the choroid from clinical SD-OCT. Invest Ophthalmol Vis Sci, 53(12), 7510-7519. PMID: 23060139.

Antony, B. J., Abràmoff, M. D., Sonka, M., Kwon, Y. H. & Garvin, M. K. (2012). Incorporation of texture-based features in optimal graph-theoretic approach with application to the 3D segmentation of intraretinal surfaces in SD-OCT volumes. Proc SPIE Med Imag, 8314, 83141G. DOI: 10.1117/12.911491.

Lee, K., Abràmoff, M. D., Garvin, M. K. & Sonka, M. (2012). Parallel graph search: application to intraretinal layer segmentation of 3-D macular OCT scans. Proc SPIE Med Imag, 8314, 83141H.

Tang, L., Kardon, R. H., Wang, J. K., Garvin, M. K., Lee, K. & Abràmoff, M. D. (2012). Quantitative evaluation of papilledema from stereoscopic color fundus photographs. Invest Ophthalmol Vis Sci, 53(8), 4490-4497. PMID: 22661468.

Niemeijer, M., Lee, K., Garvin, M. K., Abràmoff, M. D. & Sonka, M. (2012). Registration of 3D spectral OCT volumes combining ICP with a graph-based approach. Proc SPIE Med Imag, 8314, 83141A.

Kay, C. N., Abràmoff, M. D., Mullins, R. F., Kinnick, T. R., Lee, K., Eyestone, M. E., Chung, M. M., Sohn, E. H. & Stone, E. M. (2012). Three-dimensional distribution of the vitelliform lesion, photoreceptors, and retinal pigment epithelium in the macula of patients with best vitelliform macular dystrophy. Archives of ophthalmology, 130(3), 357-64. PMID: 22084158.

Garvin, M. K., Abràmoff, M. D., Lee, K., Niemeijer, M., Sonka, M. & Kwon, Y. H. (2012). 2-D pattern of nerve fiber bundles in glaucoma emerging from spectral-domain optical coherence tomography. Investigative ophthalmology & visual science, 53(1), 483-9. PMID: 22222272.

Sanchez, C. I., Niemeijer, M., Isgum, I., Dumitrescu, A., Suttorp-Schulten, M. S., Abràmoff, M. D. & van Ginneken, B. (2012). Contextual computer-aided detection: improving bright lesion detection in retinal images and coronary calcification identification in CT scans. Medical image analysis, 16(1), 50-62. PMID: 21689964.

Lee, K., Kwon, Y. H., Garvin, M. K., Niemeijer, M., Sonka, M. & Abràmoff, M. D. (2012). Distribution of damage to the entire retinal ganglion cell pathway: quantified using spectral-domain optical coherence tomography analysis in patients with glaucoma. Archives of ophthalmology, 130(9), 1118-26. PMID: 22965586.

Joshi, V. S., Garvin, M. K., Reinhardt, J. M. & Abràmoff, M. D. (2012). Automated artery-venous classification of retinal blood vessels based on structural mapping method. Proc SPIE Med Imag, 8315, 83151C. DOI: 10.1117/12.911490.

van Dijk, H. W., Verbraak, F. D., Kok, P. H., Stehouwer, M., Garvin, M. K., Sonka, M., DeVries, J. H., Schlingemann, R. O. & Abràmoff, M. D. (2012). Early neurodegeneration in the retina of type 2 diabetic patients. Investigative ophthalmology & visual science, 53(6), 2715-9. PMID: 22427582.

Quellec, G., Lamard, M., Abràmoff, M. D., Decenci re, E., Lay, B., Erginay, A., Cochener, B. & Cazuguel, G. (2012). A multiple-instance learning framework for diabetic retinopathy screening. Medical image analysis, 16(6), 1228-40. PMID: 22850462.

Christopher, M., Moga, D. C., Russell, S. R., Folk, J. C., Scheetz, T. & Abràmoff, M. D. (2012). Validation of tablet-based evaluation of color fundus images. Retina (Philadelphia, Pa.), 32(8), 1629-35. PMID: 22495326.

Chen, X., Niemeijer, M., Zhang, L., Lee, K., Abràmoff, M. D. & Sonka, M. (2012). Three-dimensional segmentation of fluid-associated abnormalities in retinal OCT: probability constrained graph-search-graph-cut. IEEE transactions on medical imaging, 31(8), 1521-31. PMID: 22453610.

Niemeijer, M., Abràmoff, M. D., Joshi, N. & Brady, M. (2011). Comparison of classifier performance for information fusion in automated diabetic retinopathy screening. In International Symposium in Biomedical Imaging: From Nano to Macro. Chicago: IEEE Press.

Xiayu, X., Niemeijer, M., Song, Q., Garvin, M., Reinhart, J. & Abràmoff, M. D. (2011). Retinal vessel width measurements based on a graph-theoretic method. In International Symposium in Biomedical Imaging: From Nano to Macro. pp. 641-644. Chicago: IEEE Press.

Quellec, G., Russell, S. R., Seddon, J. M., Reynolds, R., Scheetz, T., Mahajan, V. B., Stone, E. M. & Abràmoff, M. D. (2011). Automated discovery and quantification of image-based complex phenotypes: a twin study of drusen phenotypes in age-related macular degeneration. Investigative ophthalmology & visual science, 52(12), 9195-206. PMID: 22039249.

Roller, A. B., Folk, J. C., Patel, N. M., Boldt, H. C., Russell, S. R., Abràmoff, M. D. & Mahajan, V. B. (2011). Intravitreal bevacizumab for treatment of proliferative and nonproliferative type 2 idiopathic macular telangiectasia. Retina (Philadelphia, Pa.), 31(9), 1848-55. PMID: 21610563.

Niemeijer, M., Loog, M., Abràmoff, M. D., Viergever, M. A., Prokop, M. & van Ginneken, B. (2011). On combining computer-aided detection systems. IEEE transactions on medical imaging, 30(2), 215-23. PMID: 20813633.

Tang, L., Niemeijer, M. & Abràmoff, M. D. (2011). Splat feature classification: detection of the presence of large retinal hemorrhages. In International Symposium in Biomedical Imaging: From Nano to Macro. pp. 681-684. Chicago: IEEE Press.

Quellec, G., Russell, S. R. & Abràmoff, M. D. (2011). Optimal filter framework for automated, instantaneous detection of lesions in retinal images. IEEE transactions on medical imaging, 30(2), 523-33. PMID: 21292586.

Sanchez, C. I., Niemeijer, M., Dumitrescu, A. V., Suttorp-Schulten, M. S., Abràmoff, M. D. & van Ginneken, B. (2011). Evaluation of a computer-aided diagnosis system for diabetic retinopathy screening on public data. Investigative ophthalmology & visual science, 52(7), 4866-71. PMID: 21527381.

Mahajan, V. B., Elkins, K. A., Russell, S. R., Boldt, H. C., Gehrs, K. M., Weingeist, T. A., Stone, E. M., Abràmoff, M. D., Liu, D. & Folk, J. C. (2011). Bilateral intravitreal injection of antivascular endothelial growth factor therapy. Retina (Philadelphia, Pa.), 31(1), 31-5. PMID: 21187731.

Niemeijer, M., Xu, X., Dumitrescu, A. V., Gupta, P., van Ginneken, B., Folk, J. C. & Abràmoff, M. D. (2011). Automated measurement of the arteriolar-to-venular width ratio in digital color fundus photographs. IEEE transactions on medical imaging, 30(11), 1941-50. PMID: 21690008.

Mahajan, V. B., Tarantola, R. M., Graff, J. M., Boldt, H. C., Abràmoff, M. D., Russell, S. R. & Folk, J. C. (2011). Sutureless triplanar sclerotomy for 23-gauge vitrectomy. Archives of ophthalmology, 129(5), 585-90. PMID: 21555611.

Tang, L., Garvin, M. K., Lee, K., Alward, W. L., Kwon, Y. H. & Abràmoff, M. D. (2011). Robust multiscale stereo matching from fundus images with radiometric differences. IEEE transactions on pattern analysis and machine intelligence, 33(11), 2245-58. PMID: 21464502.

Antony, B., Abràmoff, M. D., Tang, L., Ramdas, W. D., Vingerling, J. R., Jansonius, N. M., Lee, K., Kwon, Y. H., Sonka, M. & Garvin, M. K. (2011). Automated 3-D method for the correction of axial artifacts in spectral-domain optical coherence tomography images. Biomedical optics express, 2(8), 2403-16. PMID: 21833377.

Tarantola, R. M., Folk, J. C., Shah, S. S., Boldt, H. C., Abràmoff, M. D., Russell, S. R. & Mahajan, V. B. (2011). Intraoperative choroidal detachment during 23-gauge vitrectomy. Retina (Philadelphia, Pa.), 31(5), 893-901. PMID: 21273944.

Quellec, G., Russell, S. R., Scheetz, T. E., Stone, E. M. & Abràmoff, M. D. (2011). Computational quantification of complex fundus phenotypes in age-related macular degeneration and Stargardt disease. Investigative ophthalmology & visual science, 52(6), 2976-81. PMID: 21310908.

Xu, X., Niemeijer, M., Song, Q., Sonka, M., Garvin, M. K., Reinhardt, J. M. & Abràmoff, M. D. (2011). Vessel boundary delineation on fundus images using graph-based approach. IEEE transactions on medical imaging, 30(6), 1184-91. PMID: 21216707.

van Dijk, H. W., Verbraak, F. D., Stehouwer, M., Kok, P. H., Garvin, M. K., Sonka, M., DeVries, J. H., Schlingemann, R. O. & Abràmoff, M. D. (2011). Association of visual function and ganglion cell layer thickness in patients with diabetes mellitus type 1 and no or minimal diabetic retinopathy. Vision research, 51(2), 224-8. PMID: 20801146.

Joshi, V. S., Garvin, M. K., Reinhardt, J. M. & Abràmoff, M. D. (2011). Automated method for the identification and analysis of vascular tree structures in retinal vessel network. Proc SPIE Med Imag, 7963.

Quellec, G., Abràmoff, M. D., Cazuguel, G., Lamard, M., Cochener, B. & Roux, C. (2011). Fouille d'images multi-instance et multi-resolution appliquee au depistage de la retinopathie diabetique [Multiple-instance and multi-resolution image mining for diabetic retinopathy screening]. Ingénierie et Recherche BioMédicale: IRBM, 32(6), 342-350. DOI: 10.1016/j.irbm.2011.09.010.

Joshi, V., Garvin, M., Reinhardt, J. & Abràmoff, M. (2011). Identification and reconnection of interrupted vessels in retinal vessel segmentation. Biomedical Imaging: From Nano to Macro, 2011 IEEE International Symposium on,(Image Segmentation Methods), 1416-1420.

Xu, X., Garvin, M. K., Abràmoff, M. D. & Reinhardt, J. M. (2011). Simultaneous automatic detection of optic disc and fovea on fundus photographs. Proc. SPIE, 7962(Medical Imaging 2011: Image Processing), 79622T.

Alsuhaibani, A. H., Carter, K. D., Abràmoff, M. D. & Nerad, J. A. (2011). Utility of meibography in the evaluation of meibomian glands morphology in normal and diseased eyelids. Saudi J Ophthalmol, 25(1), 61-66. PMID: 23960903.

Li, H. K., Horton, M., Bursell, S. E., Cavallerano, J., Zimmer-Galler, I., Tennant, M., Abràmoff, M., Chaum, E., Debuc, D. C., Leonard-Martin, T., M., W. & Diabetic Retinopathy Telehealth Practice Recommendations Working Group (2011). Telehealth Practice Recommendations for Diabetic Retinopathy, Second Edition. Telemedicine journal and e-health : the official journal of the American Telemedicine Association, 17(10), 814-837. PMID: 21970573.

Kay, C. N., Sohn, E. H. & Abràmoff, M. D. (2011). Using biomarkers for retinal disease risk assessment and management. Retinal Physician, 8(6), 23-27.

Abràmoff, M. (2011). Smart retinal camera for eye diagnosis. KCRG Channel 9 news.

Hu, Z., Abràmoff, M. D., Niemeijer, M. & Garvin, M. K. (2011). Automated multimodality concurrent classification for segmenting vessels in 3D spectral OCT and color fundus images. Proc. SPIE, 7962(Medical Imaging 2011: Image Processing), 796204.

Niemeijer, M., Dumitrescu, A. V., Van Ginneken, B. & Abràmoff, M. D. (2011). Automatic localization of bifurcations and vessel crossings in digital fundus photographs using location regression. Proc SPIE Med Imag, 7965, 796507. DOI: 10.1117/12.878364.

Lee, K., Abràmoff, M. D., Sonka, M. & Garvin, M. K. (2011). Automated segmentation of intraretinal layers from spectral-domain macular OCT: Reproducibility of layer thickness measurements. Proc SPIE Med Imag, 7965, 796523. DOI: 10.1117/12.878242.

Quellec, G., Lee, K., Dolejsi, M., Garvin, M. K., Abràmoff, M. D. & Sonka, M. (2010). Three-dimensional analysis of retinal layer texture: identification of fluid-filled regions in SD-OCT of the macula. IEEE transactions on medical imaging, 29(6), 1321-30. PMID: 20363675.

Longmuir, S. Q., Mathews, K. D., Longmuir, R. A., Joshi, V., Olson, R. J. & Abràmoff, M. D. (2010). Retinal arterial but not venous tortuosity correlates with facioscapulohumeral muscular dystrophy severity. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus, 14(3), 240-3. PMID: 20603058.

Lee, S., Reinhardt, J. M., Cattin, P. C. & Abràmoff, M. D. (2010). Objective and expert-independent validation of retinal image registration algorithms by a projective imaging distortion model. Medical image analysis, 14(4), 539-49. PMID: 20493760.

Hu, Z., Abràmoff, M. D., Kwon, Y. H., Lee, K. & Garvin, M. K. (2010). Automated segmentation of neural canal opening and optic cup in 3D spectral optical coherence tomography volumes of the optic nerve head. Investigative ophthalmology & visual science, 51(11), 5708-17. PMID: 20554616.

Tang, L., Scheetz, T. E., Mackey, D. A., Hewitt, A. W., Fingert, J. H., Kwon, Y. H., Quellec, G., Reinhardt, J. M. & Abràmoff, M. D. (2010). Automated quantification of inherited phenotypes from color images: a twin study of the variability of optic nerve head shape. Investigative ophthalmology & visual science, 51(11), 5870-7. PMID: 20505201.

Barriga, E. S., Pattichis, M., Tso, D., Abràmoff, M. D., Kardon, R. H., Kwon, Y. H. & Soliz, P. (2010). Independent component analysis using prior information for signal detection in a functional imaging system of the retina. Med Image Anal, 15(1), 35-44. PMID: 20655800.

Abràmoff, M. D., Niemeijer, M. & Russell, S. R. (2010). Automated detection of diabetic retinopathy: barriers to translation into clinical practice. Expert Review of Medical Devices, 7(2), 287-96. PMID: 20214432.

Sanchez, C. I., Niemeijer, M., Abràmoff, M. D. & van Ginneken, B. (2010). Active learning for an efficient training strategy of computer-aided diagnosis systems: application to diabetic retinopathy screening. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 13(Pt 3), 603-10. PMID: 20879450.

Agurto, c., Murray, V., Barriga, E., Murrillo, S., Pattichis, M., Davis, H., Russell, S., Abràmoff, M. D. & Soliz, P. (2010). Multiscale AM-FM methods for diabetic retinopathy lesion detection. IEEE Trans Medical Imaging, 29(2), 502-512. PMID: 20129850.

Abràmoff, M. D., Garvin, M. K. & Sonka, M. (2010). Retinal Imaging and Image Analysis. IEEE transactions on medical imaging, 3, 169-208. PMID: 21743764.

Lee, K., Niemeijer, M., Garvin, M. K., Kwon, Y. H., Sonka, M. & Abràmoff, M. D. (2010). Segmentation of the optic disc in 3-D OCT scans of the optic nerve head. IEEE transactions on medical imaging, 29(1), 159-68. PMID: 19758857.

Niemeijer, M., ...20 authors..., & Abràmoff, M. D. (2010). Retinopathy online challenge: automatic detection of microaneurysms in digital color fundus photographs. IEEE transactions on medical imaging, 29(1), 185-95. PMID: 19822469.

Roller, A. B., Mahajan, V. B., Boldt, C., Abràmoff, M. D., Russell, S. R. & Folk, J. C. (2010). Effects of vitrectomy on age-related macular degeneration. Ophthalmology, 117(7), 1381-1386. PMID: 20176401.

Niemeijer, M., van Ginneken, B. & Abràmoff, M. D. (2010). Automatic determination of the artery vein ratio in retinal images. Proc SPIE Med Imag, 7624, 76240I.

Lee, S., Abràmoff, M. D. & Reinhardt, J. M. (2010). Retinal atlas statistics from color fundus images. Proc SPIE Med Imag, 7623, 762310. DOI: 10.1117/12.843714.

Hu, Z., Niemeijer, M., Abràmoff, M. D., Lee, K. & Garvin, M. K. (2010). Automated segmentation of 3-D spectral OCT retinal blood vessels by neural canal opening false positive suppression. In Medical Image Computing and Computer-Assisted Intervention (MICCAI) 2010, Part III, LNCS 6363. pp. 33-40. Springer-Verlag. PMID: 20879380.

Antony, B. J., Abràmoff, M. D., Lee, K., Sonkova, P., Gupta, P., Kwon, Y., Niemeijer, M., Hu, Z. & Garvin, M. K. (2010). Automated 3D segmentation of intraretinal layers from optic nerve head optical coherence tomography images. Proc SPIE Med Imag, 7626, 76260U.

Joshi, V., Reinhardt, J. M. & Abràmoff, M. D. (2010). Automated measurement of retinal blood vessel tortuosity. Proc SPIE Med Imag, 7624, 76243A.

Abràmoff, M. D., Reinhardt, J. M., Russell, S. R., Folk, J. C., Mahajan, V. B., Niemeijer, M. & Quellec, G. (2010). Automated early detection of diabetic retinopathy. Ophthalmology, 117(6), 1147-54. PMID: 20399502.

Tang, L., Kwon, Y. H., Alward, W., Greenlee, E. C., Lee, K., Garvin, M. K. & Abràmoff, M. D. (2010). 3D reconstruction of the optic nerve head using stereo fundus images for computer-aided diagnosis of glaucoma. Proc SPIE Med Imag, 7624, 76243D.

Van Dijk, H. W., Verbraak, F. D., Kok, P. H., Garvin, M. K., Sonka, M., Lee, K., Devries, J. H., Michels, R., van Velthoven, M. E., Schlingemann, R. O. & Abràmoff, M. D. (2010). Decreased retinal ganglion cell layer thickness in Type 1 diabetic patients. Invest Ophthalmol Vis Sci, 51(7), 3660-3665. PMID: 20130282.

Lee, K., Abràmoff, M. D., Niemeijer, M., Garvin, M. K. & Sonka, M. (2010). 3-D segmentation of retinal blood vessels in spectral-domain OCT volumes of the optic nerve head. Proc SPIE Med Imag, 7626, 76260V.

Sanchez, C. I., Niemeijer, M., Suttorp Schulten, M., Abràmoff, M. & van Ginneken, B. (2010). Improving hard exudate detection in retinal images through a combination of local and contextual information. Biomedical Imaging: From Nano to Macro, 2010 IEEE International Symposium on, 41402.

Hu, Z., Niemeijer, M., Abràmoff, M. D., Lee, K. & Garvin, M. K. (2010). Automated segmentation of 3-D spectral OCT retinal blood vessels by neural canal opening false positive suppression. Med Image Comput Comput Assist Interv, 13(Pt 3), 33-40. PMID: 20879380.

Abràmoff, M. D. (2009). Detecting retinal pathology automatically with special emphasis on diabetic retinopathy. In H. F. Jelinek , M. Cree , H. F. Jelinek , M. Cree (Eds.) Automated Image Detection of Retinal Pathology. pp. 67-73. Boca-Raton: CRC Press.

Karnowski, T. P., Aykac, D., Chaum, E., Giancardo, L., Li, Y., Tobin, K. W. & Abràmoff, M. D. (2009). Practical considerations for optic nerve location in telemedicine. Conference proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2009, 6205-9. PMID: 19965082.

Hu, Z., Niemeijer, M., Lee, K., Abràmoff, M. D., Sonka, M. & Garvin, M. (2009). Automated segmentation of the optic disc margin in 3-D optical coherence tomography images using a graph-theoretic approach. Proc. SPIE (Medical Imaging: Biomedical Applications in Molecular Structural and Functional Imaging, 7262, 72620U.

van Dijk, H. W., Kok, P. H., Garvin, M., Sonka, M., Devries, J. H., Michels, R. P., van Velthoven, M. E., Schlingemann, R. O., Verbraak, F. D. & Abràmoff, M. D. (2009). Selective loss of inner retinal layer thickness in type 1 diabetic patients with minimal diabetic retinopathy. Investigative ophthalmology & visual science, 50(7), 3404-9. PMID: 19151397.

Niemeijer, M., van Ginneken, B. & Abràmoff, M. D. (2009). Automatic classification of retinal vessels into arteries and veins. DOI: 10.1117/12.813826.

Niemeijer, M., Garvin, M. K., Van Ginneken, B., Sonka, M. & Abràmoff, M. D. (2009). A linking framework for pixel classification based retinal vessel segmentation. Proc SPIE Med Imag, 7262, 726216.

Kwon, Y. H., Adix, M., Zimmerman, M. B., Piette, S., Greenlee, E. C., Alward, W. L. & Abràmoff, M. D. (2009). Variance owing to observer, repeat imaging, and fundus camera type on cup-to-disc ratio estimates by stereo planimetry. Journal of glaucoma, 18(4), 305-10. PMID: 19365196.

Sanchez, C. I., Niemeijer, M., Kockelkorn, T., Abràmoff, M. D. & van Ginneken, B. (2009). Active learning approach for detection of hard exudates,cotton wool spots and drusen in retinal images. Proc SPIE Med Imag, 7260, 72601I.

Niemeijer, M., Van Ginneken, B. & Abràmoff, M. D. (2009). Automatic classification of retinal vessels into arteries and veins. Proc SPIE Med Imag, 7260, 72601F.

Garvin, M. K., Abràmoff, M. D., Wu, X., Burns, T. K., Russell, S. R. & Sonka, M. (2009). Automated 3-D intraretinal layer segmentation of macular spectral-domain optical coherence tomography images. IEEE Trans Med Imaging, 28(9), 1436-1447. PMID: 19278927.

Lee, K., Niemeijer, M., Garvin, M. K., Kwon, Y. H., Sonka, M. & Abràmoff, M. D. (2009). 3-D segmentation of the rim and cup in spectral-domain optical coherence tomography volumes of the optic nerve head. Proc SPIE Med Imag, 7262, 72622D (9 pp.).

Ts'o, D., Schallek, J., Kwon, Y., Kardon, R., Abràmoff, M. & Soliz, P. (2009). Noninvasive functional imaging of the retina reveals outer retinal and hemodynamic intrinsic optical signal origins. Jpn J Ophthalmol, 53(4), 334-344. PMID: 19763750.

Davis, H., Russell, S., Barriga, E., Abràmoff, M. & Soliz, P. (2009). Vision-based, real-time retinal image quality assessment. CBMS 2009. 22nd IEEE International Symposium on Computer-Based Medical Systems. DOI: 10.1109/CBMS.2009.5255437.

Chiang, M. F., Boland, M. V., Margolis, J. W., Lum, F., Abràmoff, M. D. & Hildebrand, P. L. (2009). Electronic Health Records [reply]. Ophthalmology, 116(5), 1019.

Karnowski, T. P., Aykac, D., Chaum, E., Giancardo, L., Li, Y., Tobin Jr, K. W. & Abràmoff, M. D. (2009). Evaluating the accuracy of optic nerve detections in retina imaging using complementary methods.

Barriga, E. S., Murray, V., Agurto, C., Pattichis, M. S., Russell, S., Abràmoff, M. D., Davis, H. & Soliz, P. (2009). Multi-scale AM-FM for lesion phenotyping on age-related macular degeneration. CBMS 2009. 22nd IEEE International Symposium on Computer-Based Medical Systems. DOI: 10.1109/CBMS.2009.5255398.

Niemeijer, M., Abràmoff, M. D. & van Ginneken, B. (2009). Information fusion for diabetic retinopathy CAD in digital color fundus photographs. IEEE Trans Medical Imaging, 28(5), 775-785. PMID: 19150786.

Sánchez, C., Niemeijer, M., Kockelkorn, T., Abràmoff, M. D. & van Ginneken, B. (2009). Active learning approach for detection of hard exudates, cotton wool spots and drusen in retinal images.

Niemeijer, M., Garvin, M. K., Lee, K., Van Ginneken, B., Abràmoff, M. D. & Sonka, M. (2009). Registration of 3D spectral OCT volumes using 3D SIFT feature point matching. Proc SPIE Med Imag, 7259.

Niemeijer, M., Abràmoff, M. D. & van Ginneken, B. (2009). Publicly available retinal image data and the use of competitions to standardize algorithm performance comparison. (Vols. 25). (11), pp. 175-178. IFMBE Proceedings (World Congress on Medical Physics and Biomedical Engineering).

Abràmoff, M. D., Lee, K., Niemeijer, M., Alward, W. L., Greenlee, E. C., Garvin, M. K., Sonka, M. & Kwon, Y. H. (2009). Automated segmentation of the cup and rim from spectral domain OCT of the optic nerve head. Investigative ophthalmology & visual science, 50(12), 5778-84. PMID: 19608531.

Niemeijer, M., Abràmoff, M. D. & van Ginneken, B. (2009). Fast detection of the optic disc and fovea in color fundus photographs. Medical image analysis, 13(6), 859-70. PMID: 19782633.

Schallek, J., Kardon, R., Kwon, Y., Abràmoff, M., Soliz, P. & Ts'o, D. (2009). Stimulus-Evoked Intrinsic Optical Signals in the Retina: Pharmacologic Dissection Reveals Outer Retinal Origins. Invest Ophthalmol Vis Sci, 50(10), 4873-4880. DOI: 10.1167/iovs.08-3291.

Lee, A. G., Oetting, T., Beaver, H. A., Carter, K. & Task Force on the ACGME Competencies at the University of Iowa Department of Ophthalmology [included Abràmoff MD], (2009). The ACGME Outcome Project in ophthalmology: practical recommendations for overcoming the barriers to local implementation of the national mandate. Surv Ophthalmol, 54(4), 507-517. PMID: 19539838.

Schallek, J., Li, H. K., Kardon, R., Kwon, Y., Abràmoff, M., Soliz, P. & et, a. (2009). Stimulus-Evoked Intrinsic Optical Signals in the Retina: Spatial and temporal characteristics. Invest Ophthalmol Vis Sci, 50(10), 4865-4872. DOI: 10.1167/iovs.08-3290.

Lee, A. G., Golnik, K. C., Oetting, T. A., Beaver, H. A., Boldt, H. C., Olson, R., Greenlee, E., Abràmoff, M. D., Johnson, A. T. & Carter, K. (2008). Re-engineering the resident applicant selection process in ophthalmology: a literature review and recommendations for improvement. Survey of ophthalmology, 53(2), 164-76. PMID: 18348881.

Abràmoff, M. D., Folk, J. C., Lee, A. G., Beaver, H. A. & Boldt, H. C. (2008). Teaching and assessing competency in retinal lasers in ophthalmology residency. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye, 39(4), 270-80. PMID: 18717431.

Chiang, M. F., Boland, M. V., Margolis, J. W., Lum, F., Abràmoff, M. D. & Hildebrand, P. L. (2008). Adoption and perceptions of electronic health record systems by ophthalmologists: an American Academy of Ophthalmology survey. Ophthalmology, 115(9), 1591-7; quiz 1597.e1-5. PMID: 18486218.

Abràmoff, M. D., Niemeijer, M., Suttorp-Schulten, M. S., Viergever, M. A., Russell, S. R. & van Ginneken, B. (2008). Evaluation of a system for automatic detection of diabetic retinopathy from color fundus photographs in a large population of patients with diabetes. Diabetes care, 31(2), 193-8. PMID: 18024852.

Niemeijer, M., Abràmoff, M. D. & van Ginneken, B. (2008). Automated localization of the optic disc and the fovea. Conference proceedings : Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2008, 3538-41. PMID: 19163472.

Karnowski, T. P., Govindasamy, V., Tobin, K. W., Chaum, E. & Abràmoff, M. D. (2008). Retina lesion and microaneurysm segmentation using morphological reconstruction methods with ground-truth data. Conference proceedings : Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2008, 5433-6. PMID: 19163946.

Giancardo, L., Abràmoff, M. D., Chaum, E., Karnowski, T. P., Meriaudeau, F. & Tobin, K. W. (2008). Elliptical local vessel density: a fast and robust quality metric for retinal images. Conference proceedings : Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2008, 3534-7. PMID: 19163471.

Garvin, M. K., Abràmoff, M. D., Kardon, R., Russell, S. R., Wu, X. & Sonka, M. (2008). Intraretinal layer segmentation of macular optical coherence tomography images using optimal 3-D graph search. IEEE transactions on medical imaging, 27(10), 1495-505. PMID: 18815101.

Tobin, K. W., Abràmoff, M. D., Chaum, E., Giancardo, L., Govindasamy, V., Karnowski, T. P., Tennant, M. T. & Swainson, S. (2008). Using a patient image archive to diagnose retinopathy. Conference proceedings : Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2008, 5441-4. PMID: 19163948.

Agurto, C., Murillo, S., Murray, V., Pattichis, M., Russell, S., Abràmoff, M. & Soliz, P. (2008). Detection and phenotyping of retinal disease using AM-FM processing for feature extraction. art. no. 5074489. 42nd Asilomar Conference on Signals, Systems and Computers, 2008, 659-663.

Niemeijer, M., Garvin, M. K., van Ginneken, B., Sonka, M. & Abràmoff, M. D. (2008). Vessel segmentation in 3D spectral OCT scans of the retina. Proc SPIE Med Imag, 6914, 69141R-1-8.

Abràmoff, M. D. (2008). Detecting retinal pathology automatically with special emphasis on diabetic retinopathy. In M. Cree , M. Cree (Eds.) Automated Image Detection of Retinal Pathology. Springer.

Soliz, P., Russell, S. R., Abràmoff, M. D., Murillo, S., Pattichis, M. & Davis, H. (2008). Independent component analysis for vision-inspired classification of retinal images with age-related macular degeneration. 2008 IEEE Southwest Symposium on Image Analysis and Interpretation, 24-26 March, 65-68.

Abràmoff, M. (2008). Diabetic Retinopathy: Automated Detection? by C. Kent. Review of Ophthalmology.

Lee, S., Abràmoff, M. D. & Reinhardt, J. M. (2008). Retinal Image Mosaicing using the Radial Distortion Correction (RADIC) Model. Proc SPIE Med Imag, 6914, article 691435 (9 pages).

Barriga, E. S., Pattichis, M., Ts'o, D., Abràmoff, M., Kardon, R., Kwon, Y. & Soliz, P. (2007). Spatiotemporal independent component analysis for the detection of functional responses in cat retinal images. IEEE Trans Med Imaging, 26(8), 1035-45. PMID: 17695124.

Lee, S., Abràmoff, M. D. & Reinhardt, J. M. (2007). Feature-based pairwise retinal image registration by radial distortion correction. Proc SPIE Med Imag, 6512, 651220 (10 pp.).

Abràmoff, M. D. (2007). ROC: Retinopathy online challenge.

Barriga, E. S., Pattichis, M., Abràmoff, M., T'so, D., Kwon, Y., Kardon, R. & Soliz, P. (2007). Independent component analysis for the detection of in-vivo intrinsic signals from an optical imager of retinal function. Proc. SPIE, 6426(Ophthalmic Technologies XVII), 64261K.

Haeker, M., Sonka, M., Kardon, R., Shah, V. A., Wu, X. & Abràmoff, M. D. (2007). Automated segmentation of intraretinal layers from macular optical coherence tomography images. Proc SPIE Med Imag, 6512, 651214 (online).

Merickel, M. B., Abràmoff, M. D., Sonka, M. & Wu, X. (2007). Segmentation of the Optic Nerve Head Combining Pixel Classification and Graph Search. Proc SPIE Med Imag, 6512, 651215(online).

Lee, A. G., Beaver, H. A., Boldt, H. C., Olson, R., Oetting, T. A., Abràmoff, M. & Carter, K. (2007). Teaching and assessing professionalism in ophthalmology residency training programs. Surv Ophthalmol, 52(3), 300-14. PMID: 17472805.

Niemeijer, M., van Ginneken, B., Russell, S. R., Suttorp-Schulten, M. S. & Abràmoff, M. D. (2007). Automated detection and differentiation of drusen, exudates, and cotton-wool spots in digital color fundus photographs for diabetic retinopathy diagnosis. Investigative ophthalmology & visual science, 48(5), 2260-7. PMID: 17460289.

Lee, A. G., Greenlee, E., Oetting, T. A., Beaver, H. A., Johnson, A. T., Boldt, H. C., Abràmoff, M., Olson, R. & Carter, K. (2007). The Iowa ophthalmology wet laboratory curriculum for teaching and assessing cataract surgical competency. Ophthalmology, 114(7), 21-6. PMID: 17475332.

Lee, A. G., Beaver, H. A., Greenlee, E., Oetting, T. A., Boldt, H. C., Olson, R., Abràmoff, M. & Carter, K. (2007). Teaching and Assessing Systems-based Competency in Ophthalmology Residency Training Programs. Surv Ophthalmol, 52(6), 680-689. PMID: 18029274.

Davis, B., Russell, S., Abràmoff, M., Nemeth, S. C., Barriga, E. S. & Soliz, P. (2007). Identification of spectral phenotypes in age-related macular degeneration patients. Proc SPIE, 6426(Ophthalmic Technologies XVII), 64261I.

Lee, S., Abràmoff, M. D. & Reinhardt, J. M. (2007). Validation of retinal image registration algorithms by a projective imaging distortion model. Conference proceedings : Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2007, 6472-5. PMID: 18003507.

Abràmoff, M. (2007). "Roundup of other Journals". Eyenet.

Niemeijer, M., Abràmoff, M. D. & van Ginneken, B. (2007). Segmentation of the optic disc, macula and vascular arch in fundus photographs. IEEE transactions on medical imaging, 26(1), 116-27. PMID: 17243590.

Abràmoff, M. D., Alward, W. L., Greenlee, E. C., Shuba, L., Kim, C. Y., Fingert, J. H. & Kwon, Y. H. (2007). Automated segmentation of the optic disc from stereo color photographs using physiologically plausible features. Investigative ophthalmology & visual science, 48(4), 1665-73. PMID: 17389498.

Haeker, M., Abràmoff, M. D., Wu, X., Kardon, R. & Sonka, M. (2007). Use of varying constraints in optimal 3-D graph search for segmentation of macular optical coherence tomography images. MICCAI, International Conference on Medical Image Computing and Computer-Assisted Intervention, 10(Pt 1), 244-51. PMID: 18051065.

Barriga, E. S., Russell, S., Abràmoff, M., Brittain, R., Nguyen, P. & Soliz, P. (2007). A device for training and computer-assisted application of panretinal photocoagulation. Proc SPIE, 6426(Ophthalmic Technologies XVII), 64261A.

Lee, A. G., Greenlee, E., Oetting, T. A., Beaver, H. A., Johnson, A. T., Boldt, H. C., Abràmoff, M., Olson, R. & Carter, K. (2007). Assessing cataract surgical competency. Ophthalmology, 114(7), 1415-1416. PMID: 17475334.

Haeker, M., Sonka, M., Kardon, R., Wu, X. & Abràmoff, M. D. (2007). Incorporation of regional information in optimal 3-D graph search with application for intraretinal layer segmentation of optical coherence tomography images. Proc MICCAI, International Conference on Medical Image Computing and Computer-Assisted Intervention, 20, 607-618.

Haeker, M., Sonka, M., Kardon, R., Wu, X. & Abràmoff, M. D. (2007). Incorporation of shape into optimal 3-D graph search for segmentation of macular optical coherence tomography images. (Vols. 20). pp. 607-618. Proceedings MICCAI, International Conference on Medical Image Computing and Computer-Assisted Intervention 2007.

Merickel Jr, M. B., Wu, X., Sonka, M. & Abràmoff, M. (2006). Optimal segmentation of the optic nerve head from stereo retinal images. Proc SPIE Med Imag, 6143 (II), 61433B.

Abràmoff, M. (2006). On telediagnosis of diabetic retinopathy. American Diabetes Association.

Abràmoff, M. D., Russell, S. (2006). Telediagnosis for diabetic retinopathy. Ophthalmology Management.

Haeker, M., Abràmoff, M., Kardon, R. & Sonka, M. (2006). Segmentation of the surfaces of the retinal layer from OCT images. Lecture Notes in Computer Science (Medical Image Computing and Computer-Assisted Intervention, MICCAI 2006 - 9th International Conference, Proceedings), 4190(LNCS - I), 800-807.

Barriga, E. S., Russell, S. R., Abràmoff, M. D., Brittain, R., Waymire, R., Edwards, A., Engstrom, R., Davis, B. & Soliz, P. (2006). A training system for photodynamic therapy using modeling and simulation. pp. 646-650. Proc 19th IEEE International Symp Computer-Based Medical Systems 2006 (CBMS). DOI: 1109/CBMS.2006.32.

Abramoff, M. D., et al Epi, Computer Aided Design system for nuclear power plant turbine tubing. Currently operational at GEC Alstom in Paris. C++, with X-windows / Motif interface libraries; 2000 lines of code.

Barriga, E. S., Pattichis, M. S., Abràmoff, M. D., Ts'o, D., Kardon, R., Kwon, Y. & Soliz, P. (2006). Spatiotemporal independent component analysis for retinal images. 40th Asilomar Conference on Signals, Systems, and Computers, ACSSC '06, 1961-1965.

Abràmoff, M. D., Niemeijer, M. (2006). The automatic detection of the optic disc location in retinal images using optic disc location regression. Conference proceedings: 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society, 1, 4432-5. PMID: 17947087.

Abràmoff, M. D., Kwon, Y. H., Ts'o, D., Soliz, P., Zimmerman, B., Pokorny, J. & Kardon, R. (2006). Visual stimulus-induced changes in human near-infrared fundus reflectance. Investigative ophthalmology & visual science, 47(2), 715-21. PMID: 16431972.

Niemeijer, M., Abràmoff, M. D. & van Ginneken, B. (2006). Image structure clustering for image quality verification of color retina images in diabetic retinopathy screening. Medical image analysis, 10(6), 888-98. PMID: 17138215.

Abràmoff, M. D. (2006). The effect of compression on clinical diagnosis of glaucoma based on non-analyzed confocal scanning laser ophthalmoscopy images. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye, 37(3), 263; author reply 263-4. PMID: 16749269.

Niemeijer, M., van Ginneken, B., Staal, J., Suttorp-Schulten, M. S. & Abràmoff, M. D. (2005). Automatic detection of red lesions in digital color fundus photographs. IEEE transactions on medical imaging, 24(5), 584-92. PMID: 15889546.

Niemeijer, M., van Ginneken, B., ter Haar, F. & Abràmoff, M. D. (2005). Automatic detection of the optic disc, fovea and vascular arch in digital color photographs of the retina. In W. F. Clocksin , A. W. Fitzgibbon , P. H. Torr & W. F. Clocksin , A. W. Fitzgibbon , P. H. Torr (Eds.) Proceedings of the British Machine Vision Conference (16th, Oxford Brookes University, 5-8 Sept). pp. 109-118. Oxford: BMVA.

Abramoff, M. D., Niemeijer IDx-DR. Fully automated diabetic retinopathy and vessel analysis package, tested on over 100,000 people with diabetes.

Abramoff, M. D., Sonka, M. & Lee, K. OCTAnalyzer. Fully automated retinal layer and optic nerve head segmentation package, with visualization.

Barriga, E. S., Pattichis, M. S., Ts'o, D. Y., Kwon, Y., Kardon, R., Abràmoff, M. D. & Soliz, P. (2006). Detection of low amplitude, in-vivo intrinsic signals from an optical imager of retinal function. Ophthalmic Technologies XVI. Proceedings of the SPIE, 6138, 66-77.

Abràmoff, M. (2006). Telediagnosis for diabetic retinopathy. KCRG Channel 9 news.

Abràmoff, M. D., Suttorp-Schulten, M. S. (2005). Web-based screening for diabetic retinopathy in a primary care population: the EyeCheck project. Telemedicine journal and e-health : the official journal of the American Telemedicine Association, 11(6), 668-74. PMID: 16430386.

Niemeijer, M., Abràmoff, M. D. & van Ginneken, B. (2005). Automatic detection of the presence of bright lesions in colour fundus photographs. Proceedings of IFMBE Conference on Biomedical Engineering, 11(1), 1832-1838.

Abramoff, M. D., Mark & Scheetz, T. Truthmarker. iPad app available in Apple app store for dynamic annotation of image based experiments, With Mark, Scheetz.

Abramoff, M. D. TruthseekerJ. Complete image annotation and description system that is also used for educational testing and adaptive testing, fully configurable in XML, runs online on any operating system. Open source, written in Java.

Abràmoff, M. D. (2005). Imaging and Microscopy CD-Rom. Purdue University Cytology Laboratory.

Abràmoff, M. D. (2004). New developments in imaging of orbital tumors. In Z. Kercioglu , Z. Kercioglu (Eds.) Imaging Orbital Tumors. (2) New York, NY: Elsevier Science.

Abramoff, M. D. (2004). Full pixel classification training and testing system, used for pixel classification of the optic disc, retinal vessels and OCT images, written in Java and based on ImageJ.

Abràmoff, M. D., Magalhâes, P. J. & Ram, S. J. (2004). Image processing with ImageJ. Biophotonics International, 11(7), 36-42.

Staal, J., Abràmoff, M. D., Niemeijer, M., Viergever, M. A. & van Ginneken, B. (2004). Ridge-based vessel segmentation in color images of the retina. IEEE transactions on medical imaging, 23(4), 501-9. PMID: 15084075.

Abràmoff, M. D. (2004). New concepts in orbital imaging. In Z. A. Karcioglu , Z. A. Karcioglu (Eds.) Orbital tumors: diagnosis and treatment. pp. 104-112. New York, NY: Elsevier Science.

Niemeijer, M., Staal, J., Van Ginneken, B., Loog, M. & Abràmoff, M. D. (2004). Comparative study of retinal vessel segmentation methods on a new publicly available database. Proc SPIE Med Imag, 5370, 648-656. DOI: 10.1117/12.535349.

Abràmoff, M. D., Kwon, Y. H., Ts'o, D., Li, H., Berriga, S., Soliz, P. & Kardon, R. (2004). A spatial truncation approach to the analysis of optical imaging of the retina in humans and cats. Biomedical Imaging: Nano to Macro, 2004. IEEE International Symposium on, 1115-1118.

van Leiden, H. A., Moll, A. C., Dekker, J. M., Abràmoff, M. D. & Polak, B. C. (2003). Photography or ophthalmoscopy for detection of diabetic retinopathy?. Diabetes care, 26(4), 1318-9. PMID: 12663621.

Abràmoff, M. D. (2002). Functional anatomy of the orbit. Tijdschrift voor Orthoptie, 27(2), 50-55.

Abràmoff, M. (2002). Imaging at the Department of Ophthalmology of the VU in Amsterdam. Eurotimes.

Abràmoff, M. (2002). Healthcare and IT. Management Team.

Abràmoff, M. D. (2002). Challenges in realizing the potential of telemedicine in healthcare. Health Management Forum.

Abràmoff, M. (2002). EyeCheck, screening for diabetic retinopathy over the internet. Financieel Dagblad.

Abràmoff, M. D., Kalmann, R., de Graaf, M. E., Stilma, J. S. & Mourits, M. P. (2002). Rectus extraocular muscle paths and decompression surgery for Graves orbitopathy: mechanism of motility disturbances. Investigative ophthalmology & visual science, 43(2), 300-7. PMID: 11818370.

Staal, J., Kalitzin, S. N., Abràmoff, M. D., Berendschot, T., van Ginneken, B. & Viergever, M. A. (2002). Classifying convex sets for vessel detection in retinal images. In Proceedings of the First International Symposium on Biomedical Imaging, Washington, DC. pp. 269-272. Chicago: IEEE Press.

Abràmoff, M. D., Viergever, M. A. (2002). Computation and visualization of three-dimensional soft tissue motion in the orbit. IEEE transactions on medical imaging, 21(4), 296-304. PMID: 12022618.

Abramoff, M. D. (2001). EyeCheck project: based on research on Electronic Health Records, Image Analysis, and Data Compression, and HTTP data transfer.

Abràmoff, M. D. (2001). Dwalingen in de methodologie. XXIX P Nederlands tijdschrift voor geneeskunde, 145(12), 602. PMID: 11294003.

Abràmoff, M. D. (2001). Objective measurement of motion in the orbit. New York, NY: Transatlantic Publishing.

Abràmoff, M. D. (2001). DRIVE: Digital Retinal Images for Vessel Extraction.

Abràmoff, M. D., Ramos, L. P., Jansen, G. H. & Mourits, M. P. (2001). Patients with persistent pain after enucleation studied by MRI dynamic color mapping and histopathology. Investigative ophthalmology & visual science, 42(10), 2188-92. PMID: 11527929.

Abràmoff, M. D., Van Gils, A. P., Jansen, G. H. & Mourits, M. P. (2000). MRI dynamic color mapping: a new quantitative technique for imaging soft tissue motion in the orbit. Investigative ophthalmology & visual science, 41(11), 3256-60. PMID: 11006211.

Abràmoff, M. D., Niessen, W. J. & Viergever, M. A. (2000). Objective quantification of the motion of soft tissues in the orbit. IEEE transactions on medical imaging, 19(10), 986-95. PMID: 11131496.

Abramoff, M. D., Staal, J. J., Suttorp, M. S., Polak, B. C. & Viergever, M. A. (2000). Low level screening of exudates and haemorraghes in background diabetic retinopathy. In Proceedings of The First Computer Aided Fundus Image Analysis Conference, May 2000. pp. 46. Aarhus, Denmark .

Abramoff, M. D. (2000). WebScreen, telediagnosis infrastructure, for ophthalmological and other large image diagnosis over the internet. Configurable electronic patient record system, DICOM and HL7 compatible, 512-bit RSA key security, image databases, full web-enabled management system, SSL (https) security. Project design, 2 developers; Java; 18000 lines of documented Java. FDA approved for Reading Centers.

Abràmoff, M. D. (1999). Functional anatomy of the orbit: imaging aspects. In Course book, 7th Rotterdam international skull base day. pp. 35-47. Rotterdam, Netherlands: Skull Base Society.

Abramoff, M. D. (1997). StimulatorJ, functional imaging stimulation package.

Abramoff, M. D., Rasband, W. (1997). ImageJ open source, freeware image processing.

Abramoff, M. D. (1997). BIJ, biomedical image analysis programs within the ImageJ framework, including volume rendering (VolumeJ), optical flow computation (FlowJ), principal component eigenimage analysis, mutual information image registration, volume convolution, interpolation. Multiplatform, public domain, fully documented API.

Stuijfzand, E. P., Abràmoff, M. D., Zuijderveld, K. J., Ramos, L., Weickert, J., Mourits, M. P., Zonneveld, F. W. & Mali, W. (1997). Fast cinematic magnetic resonance imaging of the eye and orbit. Electr J Radiol Soc N Amer,(1).

Liem, T. A., Abràmoff, M. D. & DeLint, P. J. (1997). Localization of retinal dysfunction after cataract surgery. Investigative Ophthalmology & Visual Science, 38(4), 1840.

Abràmoff, M. D., Stuijfzand, E. P., Mali, W. P. & et al. (1997). Reattachments after orbital surgery shown by kinematic MR imaging. Radiology, 205, 553.

Abràmoff, M. D., Korf, J. (1996). Beeldverwerkende technieken bij schizofrenie en de pathogenese van de psychose. In J. A. Den Boer , R. J. Van Den Bosch , J. A. Den Boer , R. J. Van Den Bosch (Eds.) Leerboek schizofrenie. pp. 174-197. Utrecht: Tijdstroom.

Abràmoff, M. D., Braamhof, M. D. (1991). Spatiotemporally correlating neurons. [IEICE Japan] Neurocomputing issue, 90(95), 161-164.

Abràmoff, M. D., Braamhof, M. D. (1991). Spatiotemporal correlation in the cerebellum. IEICE Neurocomputing issue, 90, 1739-1942.

Abràmoff, M. D. (1991). Spatiotemporal correlation and the cerebellum. IEEE-INNS International joint conference on neural networks II, 609-612.

Abràmoff, M. D. (1991). Can neural networks explain dysfluent speech. In Speech motor control and stuttering. Proceedings of the 2nd international conference on speech motor control and stuttering. pp. 181-188. Amsterdam: Elsevier.

Abràmoff, M. D. (1990). Can neural networks explain stuttering?. In R. O. Moore , S. Bengtsson , J. R. Bryant , J. S. Bryden , R. O. Moore , S. Bengtsson , J. R. Bryant , J. S. Bryden (Eds.) Medical Informatics Europe '90. pp. 748-751. Berlin: Springer Verlag.

Abramoff, M. D. (1990). Neural network of brain analysis tool, allowed simulation of spike train processing by multiple dendritic trees. C and Windows 3.0; 5000 lines of code.

Abramoff, M. D. (1986). Worstbak, process control for food processing factories. C on dedicated Z-80 boards, including design of hardware, 10,000 lines of code (1986-1988).

Abramoff, M. D. (1981). Mike*, computer-aided software design environment for automatic generation of administrative software, including credit analyses, customer databases. Basic, 30,000 lines of code. (1981-1984).