Publications

Datta, P., Hendrickson, B., Brendalen, S., Ruffcorn, A. & Seo, S. (2019). The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors. The Journal of biological chemistry, 294(50), 19119-19136. PMID: 31694913.

Weihbrecht, K., Goar, W. A., Carter, C. S., Sheffield, V. C. & Seo, S. (2018). Genotypic and phenotypic characterization of the Sdccag8Tn(sb-Tyr)2161B.CA1C2Ove mouse model. PloS one, 13(2), e0192755. PMID: 29444170.

Hsu, Y., Garrison, J. E., Kim, G., Schmitz, A. R., Searby, C. C., Zhang, Q., Datta, P., Nishimura, D. Y., Seo, S. & Sheffield, V. C. (2017). BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment. PLoS genetics, 13(10), e1007057. PMID: 29049287.

Seo, S., Datta, P. (2017). Photoreceptor outer segment as a sink for membrane proteins: hypothesis and implications in retinal ciliopathies. Human Molecular Genetics, 26(R1), R75-R82. PMID: 28453661.

Dutta, N., Seo, S. (2016). RPGR, a prenylated retinal ciliopathy protein, is targeted to cilia in a prenylation- and PDE6D-dependent manner. Biology Open, 5(9), 1283-1289. PMID: 27493202.

Bullard, S. A., Seo, S., Schilling, B., Dyle, M. C., Dierdorff, J. M., Ebert, S. M., DeLau, A. D., Gibson, B. W. & Adams, C. M. (2016). Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4. The Journal of biological chemistry, 291(34), 17496-17509. PMID: 27358404.

Biswal, M. R., Ildefonso, C. J., Mao, H., Seo, S. J., Wang, Z., Li, H., Le, Y. Z. & Lewin, A. S. (2016). Conditional Induction of Oxidative Stress in RPE: A Mouse Model of Progressive Retinal Degeneration. Advances in experimental medicine and biology, 854, 31-37. PMID: 26427390.

Lee, J. J., Seo, S. (2015). PDE6D binds to the C-terminus of RPGR in a prenylation-dependent manner. (Vols. 16). (12), pp. 1581-1582. EMBO reports. PMID: 26553938.

Datta, P., Allamargot, C., Hudson, J. S., Andersen, E. K., Bhattarai, S., Drack, A. V., Sheffield, V. C. & Seo, S. (2015). Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome. Proceedings of the National Academy of Sciences of the United States of America, 112(32), E4400-E4409. PMID: 26216965.

Plotnikova, O. V., Seo, S., Cottle, D. L., Conduit, S., Hakim, S., Dyson, J. M., Mitchell, C. A. & Smyth, I. M. (2015). INPP5E interacts with AURKA, linking phosphoinositide signaling to primary cilium stability. Journal of cell science, 128(2), 364-372. PMID: 25395580.

Swiderski, R. E., Nakano, Y., Mullins, R. F., Seo, S. & Bánfi, B. (2014). A Mutation in the Mouse Ttc26 Gene Leads to Impaired Hedgehog Signaling. PLoS Genetics, 10(10), e1004689. PMID: 25340710.

Zhang, Y., Seo, S., Bhattarai, S., Bugge, K., Searby, C. C., Zhang, Q., Drack, A. V., Stone, E. M. & Sheffield, V. C. (2014). BBS mutations modify phenotypic expression of CEP290-related ciliopathies. Hum Mol Genet, 23(1), 40-51. PMID: 23943788.

Nelson, N. G., Skeie, J. M., Muradov, H., Rowell, H. A., Seo, S. & Mahajan, V. B. (2014). CAPN5 gene silencing by short hairpin RNA interference. BMC Res Notes, 7(1), 642.

Sinha, S., Belcastro, M., Datta, P., Seo, S. & Sokolov, M. (2014). Essential Role of the Chaperonin CCT in Rod Outer Segment Biogenesis. Invest Ophthalmol Vis Sci, 55(6), 3775-3785.

Chamling, X., Seo, S., Searby, C. C., Kim, G., Slusarski, D. C. & Sheffield, V. C. (2014). The Centriolar Satellite Protein AZI1 Interacts with BBS4 and Regulates Ciliary Trafficking of the BBSome. PLoS Genet, 10(2), e1004083. PMID: 24550735.

Seo, S., Solivan-Timpe, F., Roos, B. R., Robin, A. L., Stone, E. M., Kwon, Y. H., Alward, W. L. & Fingert, J. H. (2013). Identification of Proteins that Interact with TANK Binding Kinase 1 and Testing for Mutations Associated with Glaucoma. Curr. Eye. Res., 38(2), 310-5. PMID: 23286385.

Chamling, X., Seo, S., Bugge, K., Searby, C., Guo, D. F., Drack, A. V., Rahmouni, K. & Sheffield, V. C. (2013). Ectopic expression of human BBS4 can rescue Bardet-Biedl syndrome phenotypes in Bbs4 null mice. PLoS One, 8(3), e59101. PMID: 23554981.

Drack, A. V., Mullins, R. & Seo, S. (2013). Retinitis Pigmentosa Syndromes: Bardet-Biedl Syndrome. In M. E. Hartnett , M. Trese & A. Capone (Eds.) Pediatric Retina. pp. 259068. Philadelphia: Lippincott.

Seo, S., Mullins, R. F., Dumitrescu, A. V., Bhattarai, S., Gratie, D., Wang, K., Stone, E. M., Sheffield, V. & Drack, A. V. (2013). Subretinal gene therapy of mice with Bardet-Biedl syndrome type 1. Invest Ophthalmol Vis Sci, 54(9), 6118-32. PMID: 23900607.

Carter, C. S., Vogel, T. W., Zhang, Q., Seo, S., Swiderski, R. E., Moninger, T. O., Cassell, M. D., Thedens, D. R., Keppler-Noreuil, K. M., Nopoulos, P., Nishimura, D. Y., Searby, C. C., Bugge, K. & Sheffield, V. C. (2012). Abnormal development of NG2+PDGFR-a+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model. Nat. Med., 18(12), 1797-804. PMID: 23160237.

Humbert, M. C., Weihbrecht, K., Searby, C. C., Li, Y., Pope, R. M., Sheffield, V. C. & Seo, S. (2012). ARL13B, PDE6D and CEP164 form a functional network for INPP5E ciliary targeting. Proc. Natl. Acad. Sci. USA., 109(48), 19691-6. PMID: 23150559.

Zhang, Q., Yu, D., Seo, S., Stone, E. M. & Sheffield, V. C. (2012). Intrinsic protein-protein interaction mediated and chaperonin assisted sequential assembly of a stable Bardet-Biedl syndrome protein complex, the BBSome. J Biol Chem, 287(24), 20625-20635. PMID: 22500027.

Zhang, Q., Seo, S., Bugge, K., Stone, E. M. & Sheffield, V. C. (2012). BBS proteins interact genetically with the IFT pathway to influence SHH related phenotypes. Hum Mol Genet, 21(9), 1945-1953. PMID: 22228099.

Zhang, Q., Nishimura, D., Seo, S., Vogel, T., Morgan, D., Searby, C., Bugge, K., Stone, E., Rhamouni, K. & Sheffield, V. (2011). Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS associated phenotypes and Bbs3 unique phenotypes. Proc. Natl. Acad. Sci. USA., 108(51), 20678-20683. PMID: 22139371.

Seo, S., Zhang, Q., Bugge, K., Breslow, D. K., Searby, C. C., Nachury, M. V. & Sheffield, V. C. (2011). A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened. PLoS Genet, 7(11), e1002358. PMID: 22072986.

Sang, L., Miller, J. J., Corbit, K. C., Giles, R. H., Brauer, M. J., Otto, E. A., Baye, L. M., Wen, X., Scales, S. J., Kwong, M., Huntzicker, E. G., Sfakianos, M. K., Sandoval, W., Bazan, J. F., Kulkarmi, P., Giarcia-Gonzalo, F. R., Seol, A. D., O'Toole, J. F., Held, S., Reutter, H. M., Lane, W. S., Rafiq, M. A., Noor, A., Ansar, M., Devi, A. R., Sheffield, V. C., Slusarski, D. C., Vincent, J. B., Doherty, D. A., Hildebrandt, F., Reiter, J. F. & Jackson, P. K. (2011). Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways. Cell, 145(4), 513-28. PMID: 21565611.

Seo, S., Baye, L. M., Schulz, N. P., Beck, J. S., Zhang, Q., Slusarski, D. C. & Sheffield, V. C. (2010). BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly. Proc Natl Acad Sci U S A, 107(4), 1488-93. PMID: 20080638.

Seo, S., Guo, D. F., Bugge, K., Morgan, D. A., Rahmouni, K. & Sheffield, V. C. (2009). Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling. Hum Mol Genet, 18(7), 1323-31. PMID: 19150989.

Rahmouni, K., Fath, M. A., Seo, S., Thedens, D. R., Berry, C. J., Weiss, R., Nishimura, D. Y. & Sheffield, V. C. (2008). Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome. J Clin Invest, 118(4), 1458-67. PMID: 18317593.

Seo, S., Lim, J. W., Yellajoshyula, D., Chang, L. W. & Kroll, K. L. (2007). Neurogenin and NeuroD direct transcriptional targets and their regulatory enhancers. EMBO J, 26(24), 5093-108. PMID: 18007592.

Seo, S., Kroll, K. L. (2006). Geminin's double life: chromatin connections that regulate transcription at the transition from proliferation to differentiation. Cell Cycle, 5(4), 374-9. PMID: 16479171.

Seo, S., Herr, A., Lim, J. W., Richardson, G. A., Richardson, H. & Kroll, K. L. (2005). Geminin regulates neuronal differentiation by antagonizing Brg1 activity. Genes Dev, 19(14), 1723-34. PMID: 16024661.

Seo, S., Richardson, G. A. & Kroll, K. L. (2005). The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD. Development, 132(1), 105-15. PMID: 15576411.

Seo, S., Kang, S. S., Cho, G., Rho, H. M. & Jung, G. (1997). C/EBP Alpha and C/EBP Beta Play Similar Roles in the Transcription of the Human Cu/Zn SOD Gene. Gene, 203(1), 11-15.

Cho, G., Kang, S., Seo, S., Kim, Y. & Jung, G. (1997). The Transcriptional Repression of the Human Cu/Zn Superoxide Dismutase (sod1) Gene by the Anticancer Drug Mitomycin C (MMC). Biochem Mol Biol Int, 42(5), 949-956.

Seo, S., Kim, H. T., Cho, G., Rho, H. M. & Jung, G. (1996). Sp1 and C/EBP-Related Factor Regulate the Transcription of Human Cu/ZN SOD Gene. Gene, 178(1-2), 177-185.