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Terry A. Braun, BS, MS, PhD

Portrait
Hansjoerg E. J. W. Kolder, MD, PhD, Professorship in Best Disease Research
Director, Coordinated Laboratory for Computational Genomics
Professor of Biomedical Engineering (BME)
Professor of Ophthalmology and Visual Sciences
Professor of Electrical and Computer Engineering (ECE)

Contact Information

Primary Office
5318 SC
Iowa City, IA 52242
319-335-6285

Office
5318 SC
Iowa City, IA 52242
319-335-285

Primary Office
5318 SC
319-335-6285

Education

BS, Electrical Engineering, University of Iowa
MS, Electrical and Computer Engineering, University of Iowa
PhD, Genetics, University of Iowa

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Genetics, Interdisciplinary Graduate Program in Informatics, Interdisciplinary Graduate Program in Neuroscience

Center, Program and Institute Affiliations

Carver Family Center for Macular Degeneration, Center for Bioinformatics and Computational Biology, Holden Comprehensive Cancer Center, Institute for Clinical and Translational Science, Institute for Vision Research, Iowa Institute of Human Genetics., John and Marcia Carver Nonprofit Genetic Testing Laboratory

Research Summary

Genetics; bioinformatics and computational genetics; macular degeneration.

Publications

Taylor, K. R., Booth, K. T., Azaiez, H., Sloan, C. M., Kolbe, D. L., Glanz, E. N., Shearer, A. E., DeLuca, A. P., Anand, V. N., Hildebrand, M. S., Simpson, A. C., Eppsteiner, R. W., Scheetz, T. E., Braun, T. A., Huygen, P. L., Smith, R. J. & Casavant, T. L. (2016). Audioprofile Surfaces: The 21st Century Audiogram. The Annals of otology, rhinology, and laryngology, 125(5), 361-8. PMID: 26530094.

Scheetz, T. E., Fingert, J. H., Wang, K., Kuehn, M. H., Knudtson, K. L., Alward, W. L., Boldt, H. C., Russell, S. R., Folk, J. C., Casavant, T. L., Braun, T. A., Clark, A. F., Stone, E. M. & Sheffield, V. C. (2013). A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci. PLoS One, 8(3), 358657. PMID: 23536807.00.

Gavin, A. J., Scheetz, T. E., Roberts, C. A., O'Leary, B., Braun, T., Sheffield, V. C., Soares, M. B., Robinson, J. P. & Casavant, T. L. (2002). Pooled library tissue tags for EST-based gene discovery. Bioinformatics, 18(9), 1162-6. PMID: 12217907.

Barrett, S., Beck, J. C., Bernier, R., Bisson, E., Braun, T., Casavant, T. L., Childress, D., Folstein, S. E., Garcia, M., Gardiner, M. B., Gilman, S., Haines, J. L., Hopkins, K., Landa, R., Meyer, N. H., Mullane, J. A., Nishimura, D. Y., Palmer, P., Piven, J., Purdy, J., Santangelo, S. L., Searby, C., Sheffield, V., Singleton, J. & Slager, S. (1999). An autosomal genomic screen for autism. Collaborative linkage study of autism. Am J Med Genet, 88(6), 609-15. PMID: 10581478.

Keck, K., Breheny, P., Braun, T., Darbro, B., Li, G., Dillon, J., Bellizzi, A., O'Dorisio, T. & Howe, J. (2018). Gene Expression Changes in Small Bowel Neuroendocrine Tumors Associated with Progression to Metastases. In PANCREAS. (Vols. 47). (3), pp. 343--344.

Azaiez, H., Booth, K. T., Ephraim, S. S., Crone, B., Black-Ziegelbein, E. A., Marini, R. J., Shearer, A Eliot,, Sloan-Heggen, C. M., Kolbe, D., Casavant, T. & others, (2018). Genomic Landscape and Mutational Signatures of Deafness-Associated Genes. The American Journal of Human Genetics, 103(4), 484--497.

Brogden, K. A., Parashar, D., Hallier, A. R., Braun, T., Qian, F., Rizvi, N. A., Bossler, A. D., Milhem, M. M., Chan, T. A., Abbasi, T. & others, (2018). Genomics of NSCLC patients both affirm PD-L1 expression and predict their clinical responses to anti-PD-1 immunotherapy. BMC cancer, 18(1), 225.

Schnieders, M. J., Nishimura, C., Braun, T. & Smith, R. J. (2018). Hela Azaiez, Kevin T. Booth, Sean S. Ephraim, Bradley Crone, Elizabeth A. Black-Ziegelbein, Robert J. Marini, 3 A. Eliot Shearer, 4 Christina M. Sloan-Heggen, 5 Diana Kolbe, Thomas Casavant, 3.

Scott, A. T., Tessmann, J. B., Braun, T., Darbro, B. W., Breheny, P., Bellizzi, A. M., Dillon, J. S. & O'Dorisio, T. M. (2018). Motor Neuron and Pancreas Homeobox 1 Mutations in Patients with Familial Neuroendocrine Tumors. Journal of the American College of Surgeons, 227(4), S85--S86.

Keck, K. J., Breheny, P., Braun, T. A., Darbro, B., Li, G., Dillon, J. S., Bellizzi, A. M., O'dorisio, T. M. & Howe, J. R. (2018). Changes in gene expression in small bowel neuroendocrine tumors associated with progression to metastases. Surgery, 163(1), 232--239.

Brogden, K. A., Parashar, D., Hallier, A. R., Braun, T., Qian, F., Rizvi, N. A., Bossler, A. D., Milhem, M. M., Chan, T. A., Abbasi, T. & others, (2018). Correction to: Genomics of NSCLC patients both affirm PD-L1 expression and predict their clinical responses to anti-PD-1 immunotherapy. BMC cancer, 18(1), 413.

Stone, E. M., Andorf, J. L., Whitmore, S. S., DeLuca, A. P., Giacalone, J. C., Streb, L. M., Braun, T. A., Mullins, R. F., Scheetz, T. E., Sheffield, V. C. & Tucker, B. A. (2017). Clinically Focused Molecular Investigation of 1000 Consecutive Families with Inherited Retinal Disease. Ophthalmology, 124(9), 1314-1331. PMID: 28559085.

Sherman, S. K., Maxwell, J. E., Qian, Q., Bellizzi, A. M., Braun, T. A., Iannettoni, M. D., Darbro, B. W. & Howe, J. R. (2015). Esophageal cancer in a family with hamartomatous tumors and germline PTEN frameshift and SMAD7 missense mutations. Cancer genetics, 208(1), 41--46.

Bax, N. M., Sangermano, R., Roosing, S., Thiadens, A. A., Hoefsloot, L. H., van den Born, L Ingeborgh,, Phan, M., Klevering, B. J., Westeneng-van Haaften, C., Braun, T. A. & others, (2015). Heterozygous Deep-Intronic Variants and Deletions in ABCA 4 in Persons with Retinal Dystrophies and One Exonic ABCA 4 Variant. Human mutation, 36(1), 43--47.

Burnight, E. R., Wiley, L. A., Drack, A. V., Braun, T. A., Anfinson, K., Kaalberg, E. E., Halder, J., Mullins, R., Stone, E. M. & Tucker, B. A. (2014). CEP290 gene addition rescues ciliogenesis in LCA patient cells. Investigative Ophthalmology \& Visual Science, 55(13), 3300--3300.

Plichta, K., Sun, W., Anderson, C., Brown, B., Casavant, T., Braun, T. & Buatti, J. (2014). The Prognostic Value of Pretreatment FDG-PET Scans in Head and Neck Squamous Cell Cancers Treated With Definitive Chemoradiation. International Journal of Radiation Oncology• Biology• Physics, 90(1), S538.

Taylor, K. R., DeLuca, A. P., Shearer, A Eliot,, Hildebrand, M. S., Black-Ziegelbein, E. A., Anand, V. N., Sloan, C. M., Eppsteiner, R. W., Scheetz, T. E., Huygen, P. L. & others, (2013). Audio G ene: Predicting Hearing Loss Genotypes from Phenotypes to Guide Genetic Screening. Human mutation, 34(4), 539--545.

Whitmore, S. S., Zeng, S., Daggett, H., DeLuca, A., Tucker, B., Braun, T., Mullins, R., Stone, E. & Scheetz, T. (2013). Bioinformatic identification of altered splicing motifs resulting from the Alu insertion in exon 9 of the RP gene MAK. Investigative Ophthalmology \& Visual Science, 54(15), 1317--1317.

Scheetz, T., DeLuca, A., Stone, E. & Braun, T. (2013). Detection of sample contamination in clinical next-generation sequencing. Investigative Ophthalmology \& Visual Science, 54(15), 3378--3378.

Wagner, A., Taylor, K., DeLuca, A., Casavant, T., Stone, E., Mullins, R., Scheetz, T. & Braun, T. (2013). Positive and unlabeled Learning for Prioritizing Candidate Variants in Retinal Degenerative Diseases. Investigative Ophthalmology \& Visual Science, 54(15), 3376--3376.

Braun, T., Wagner, A., DeLuca, A., Casavant, T., Scheetz, T., Clark, A., Mullins, R. & Stone, E. (2013). The Ocular Tissue Database. Investigative Ophthalmology \& Visual Science, 54(15), 3383--3383.

DeLuca, A., Ephraim, S., Scheetz, T., Stone, E. & Braun, T. (2013). Vision Variation Database (VVD). Investigative Ophthalmology \& Visual Science, 54(15), 3382--3382.

Carr, J. C., Boese, E. A., Spanheimer, P. M., Dahdaleh, F. S., Martin, M., Calva, D., Schafer, B., Thole, D. M., Braun, T., O'Dorisio, T. M., O'Dorisio, M. S. & Howe, J. R. (2012). Differentiation of small bowel and pancreatic neuroendocrine tumors by gene-expression profiling. Surgery, 152(6), 998-1007. PMID: 23158174.00.

Eppsteiner, R. W., Shearer, A. E., Hildebrand, M. S., Deluca, A. P., Ji, H., Dunn, C. C., Black-Ziegelbein, E. A., Casavant, T. L., Braun, T. A., Scheetz, T. E., Scherer, S. E., Hansen, M. R., Gantz, B. J. & Smith, R. J. (2012). Prediction of cochlear implant performance by genetic mutation: the spiral ganglion hypothesis. Hear Res, 292(1-2), 51-58. PMID: 22975204.00.

Wagner, A. H., DeLuca, A. P., Casavant, T. L., Scheetz, T. E., Stone, E. M., Mullins, R. & Braun, T. A. (2012). RNA Sequencing for Identification of Genetic Factors in Retinal Disease. Investigative Ophthalmology \& Visual Science, 53(14), 4527--4527.

Putliwala, T. M., McDowell, C., Liu, Y., Casavant, T. L., Faga, B., Thole, D. M., Wordinger, R. J., Braun, T. A. & Clark, A. F. (2012). Temporal Changes In Retinal Gene Expression After Optic Nerve Crush In Mice. Investigative Ophthalmology \& Visual Science, 53(14), 3847--3847.

Eppsteiner, R. W., Schearer, A. E., Hildebrand, M. S., Taylor, K. R., Deluca, A. P., Scherer, S., Huygen, P., Scheetz, T. E., Braun, T. A., Casavant, T. L. & Smith, R. J. (2012). Using the phenome and genome to improve genetic diagnosis for deafness. Otolaryngol Head Neck Surg, 147(5), 975-977. PMID: 22785243.00.

Stone, E. M., Mullins, R. F., Tucker, B. A., Wagner, A. H., Braun, T. A., East, J. S. & Scheetz, T. E. (2012). Alternative Splicing of Exon 12 of the Male Germ Cell Associated Kinase Gene (MAK) Results in a Cone-specific Isoform. Investigative Ophthalmology \& Visual Science, 53(14), 4594--4594.

Whitmore, S. S., Braun, T. A., Scheetz, T. E., Khanna, A., Affatigato, L. M., Stone, E. M. & Mullins, R. F. (2012). ARMS2 A69S Associated Alternative Splicing and Differential Gene Expression in Human RPE/Choroid. Investigative Ophthalmology \& Visual Science, 53(14), 6501--6501.

Mahajan, V. B., Skeie, J. M., Bassuk, A. G., Fingert, J. H., Braun, T. A., Daggett, H. T., Folk, J. C., Sheffield, V. C. & Stone, E. M. (2012). Calpain-5 mutations cause autoimmune uveitis, retinal neovascularization, and photoreceptor degeneration. PLoS Genet, 8(10), e1003001. PMID: 23055945.00.

Clark, A. F., Stone, E. M., Sheffield, V. C., Fingert, J., Casavant, T. L., Scheetz, T., Braun, T. & Grundstad, A Jason, (2011). Single nucleotide polymorphisms and genes associated with age-related macular degeneration.

Meyer, K. J., Davis, L. K., Schindler, E. I., Beck, J. S., Rudd, D. S., Grundstad, A. J., Scheetz, T. E., Braun, T. A., Fingert, J. H., Alward, W. L., Kwon, Y. H., Folk, J. C., Russell, S. R., Wassink, T. H., Stone, E. M. & Sheffield, V. C. (2011). Genome-wide analysis of copy number variants in age-related macular degeneration. Hum Genet, 129(1), 91-100. PMID: 20981449.00.

DeLuca, A. P., Wagner, A. H., Taylor, K. R., Faga, B., Thole, D., Sheffield, V. C., Stone, E. M., Casavant, T. L., Scheetz, T. E. & Braun, T. A. (2011). Sequencing and disease variation detection tools and techniques. In Computer Systems and Applications (AICCSA), 2011 9th IEEE/ACS International Conference on. pp. 80--83.

Stone, E. M., DeLuca, A., Scheetz, T. E., Braun, T. A., Affatigato, L. M., Daggett, H. T., Johnston, R. M., Streb, M. R. & Sheffield, V. C. (2011). Analysis of 200 Human Exomes for Improved Mutation Detection Specificity. Investigative Ophthalmology \& Visual Science, 52(14), 3314--3314.

Taylor, K. R., DeLuca, A. P., Goodman, C. W., Tompkins, B. W., Scheetz, T. E., Hildebrand, M. S., Huygen, P. L., Smith, R. J., Braun, T. A. & Casavant, T. L. (2011). AudioGene: Computer-based prediction of genetic factors involved in non-syndromic hearing impairment. IEEE.

Davis, L. K., Meyer, K. J., Schindler, E. I., Beck, J. S., Rudd, D. S., Grundstad, A. J., Scheetz, T. E., Braun, T. A., Fingert, J. H., Alward, W. L., Kwon, Y. H., Folk, J. C., Russell, S. R., Wassink, T. H., Sheffield, V. C. & Stone, E. M. (2011). Copy number variations and primary open-angle glaucoma. Invest Ophthalmol Vis Sci, 52(10), 7122-7133. PMID: 21310917.00.

Hildebrand, M. S., Morin, M., Meyer, N. C., Mayo, F., Modamio-Hoybjor, S., Mencia, A., Olavarrieta, L., Morales-Angulo, C., Nishimura, C. J., Workman, H., Deluca, A. P., del Castillo, I., Taylor, K. R., Tompkins, B., Goodman, C. W., Schrauwen, I., Wesemael, M. V., Lachlan, K., Shearer, A. E., Braun, T. A., Huygen, P. L., Kremer, H., Van Camp, G., Moreno, F., Casavant, T. L., Smith, R. J. & Moreno-Pelayo, M. A. (2011). DFNA8/12 caused by TECTA mutations is the most identified subtype of nonsyndromic autosomal dominant hearing loss. Hum Mutat, 32(7), 825-834. PMID: 21520338.00.

Braun, T., DeLuca, A., Anand, N., Taylor, K., Bogaard, J., Faga, B., Scheetz, T., Casavant, T., Sheffield, V. & Stone, E. (2009). Automated Sequence Analysis Pipeline (ASAP) for Genetic Testing. Investigative Ophthalmology \& Visual Science, 50(13), 4133--4133.

Scheetz, T., Braun, T., Smith, R., Walls, W., Faga, B., Folk, J., Sheffield, V., Casavant, T. & Stone, E. (2009). CPS: A collaborative phenotype system. Investigative Ophthalmology \& Visual Science, 50(13), 2825--2825.

Kinnick, T., Grundstad, A., Ehlinger, M., Andorf, J., Knudtson, K., Braun, T., Scheetz, T., Sheffield, V. & Stone, E. (2009). Genomic Fragment Capture and Pyrophosphate Sequencing for Retinitis Pigmentosa Gene Discovery. Investigative Ophthalmology \& Visual Science, 50(13), 2820--2820.

Walters, J. D., Bair, T. B., Braun, T. A., Scheetz, T. E., Robinson, J. P. & Casavant, T. L. (2009). Multi-granularity Parallel Computing in a Genome-Scale Molecular Evolution Application. J Supercomput, 5698, 49-59.

Sheffield, V. C., Stone, E., Casavant, T., Braun, T. & Nishimura, D. (2008). Bardet-Biedl susceptibility gene and uses thereof.

Stone, E., Fingert, J., Braun, T., Isaak, E., Andorf, J., Streb, L., Fishman, G., Weleber, R., Jacobson, S. & Sheffield, V. (2007). A Strategy for Efficient Molecular Diagnosis of Genetically Heterogeneous Autosomal Recessive Diseases. Investigative Ophthalmology \& Visual Science, 48(13), 2333--2333.

Scheetz, T., Braun, T., Casavant, T., Sheffield, V. & Stone, E. (2007). Correlation of Gene Expression in Retinitis Pigmentosa and Bardet-Bieldl Syndrome. Investigative Ophthalmology \& Visual Science, 48(13), 2336--2336.

Braun, T., Scheetz, T., Tack, D., Burns, T., Casavant, T., Sheffield, V. & Stone, E. (2007). Development of a Collaborative Ocular Phenotype Database. Investigative Ophthalmology \& Visual Science, 48(13), 4634--4634.

Wang, W., McNatt, L., Li, X., Tack, D., Scheetz, T., Braun, T., Casavant, T. & Clark, A. (2007). Profiling Gene Expression of Human Ocular Tissues. Investigative Ophthalmology \& Visual Science, 48(13), 3797--3797.

O'Leary, B. M., Davis, S. G., Smith, M. F., Brown, B., Kemp, M. B., Almabrazi, H., Grundstad, J. A., Burns, T., Leontiev, V., Andorf, J., Clark, A. F., Sheffield, V. C., Casavant, T. L., Scheetz, T. E., Stone, E. M. & Braun, T. A. (2007). Transcript annotation prioritization and screening system (TrAPSS) for mutation screening. J Bioinform Comput Biol, 5(6), 1155-1172. DOI: 10.1142/S0219720007003132.

Scheetz, T., Kim, K., Swiderski, R., Braun, T., Huang, J., Casavant, T., Sheffield, V. & Stone, E. (2006). Identification Of Regulatory Elements In The Mammalian Eye. Investigative Ophthalmology \& Visual Science, 47(13), 5412--5412.

Bischof, J. M., Chiang, A. P., Scheetz, T. E., Stone, E. M., Casavant, T. L., Sheffield, V. C. & Braun, T. A. (2006). Genome-wide identification of pseudogenes capable of disease-causing gene conversion. Hum Mutat, 27(6), 545-552. PMID: 16671097.00.

Chang, A. P., Beck, J. S., Yen, H. J., Tayeh, M. K., Scheetz, T. E., Swiderski, R. E., Nishimura, D. Y., Braun, T. A., Kim, K. Y., Huang, J., Elbedour, K., Carmi, R., Slusarski, D. C., Casavant, T. L., Stone, E. M. & Sheffield, V. C. (2006). Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11). Proceedings of the National Academy of Sciences, 103(16), 6287-6292. PMID: 16606853.00.

Braun, T. A., Shankar, S. P., Davis, S., O'Leary, B., Scheetz, T. E., Clark, A. F., Sheffield, V. C., Casavant, T. L. & Stone, E. M. (2006). Prioritizing regions of candidate genes for efficient mutation screening. Hum Mutat, 27(2), 195-200. PMID: 16395665.00.

Steely, H. T., Dillow, G. W., Bian, L., Grundstad, J., Braun, T. A., Casavant, T. L., McCartney, M. D. & Clark, A. F. (2006). Protein expression in a transformed trabecular meshwork cell line: proteome analysis. Mol Vis, 12, 372-383. PMID: 16636656.00.

Scheetz, T. E., Kim, K. Y., Swiderski, R. E., Philp, A. R., Braun, T. A., Knudtson, K. L., Dorrance, A. M., DiBona, G. F., Huang, J., Casavant, T. L., Sheffield, V. C. & Stone, E. M. (2006). Regulation of gene expression in the mammalian eye and its relevance to eye disease. Proc Natl Acad Sci USA, 103(39), 14429-14434. PMID: 16983098.00.

Sibenaller, Z. A., Etame, A. B., Ali, M. M., Barua, M., Braun, T. A., Casavant, T. L. & Ryken, T. C. (2005). Genetic characterization of commonly used glioma cell lines in the rat animal model system. Neurosurg Focus, 19(4), E1. PMID: 16241103.00.

Shankar, S., Carelli, V., King, T., Taylor, C., Abdulkawy, H., Braun, T., Daiger, S., Salomao, SR,, Sadun, A. & Stone, E. (2005). Linkage analysis of the X chromosome in a Brazilian family with Leber hereditary optic neuropathy (LHON). Investigative Ophthalmology \& Visual Science, 46(13), 663--663.

Kirkpatrick, D. B., Sibenaller, Z. A., Etame, A. B., Ali, M. M., Barua, M., Braun, T. A., Casavant, T. L., Ryken, T. C., Ritchie, M. D., Wiesner, S. M. & others, (2005). Pages: 1 Publication Date: Oct 2005. Bioinformatics, 19(4).

Walters, J. D., Casavant, T. L., Robinson, J. P., Bair, T. B., Braun, T. A. & Scheetz, T. E. (2005). XenoCluster: a grid computing approach to finding ancient evolutionary genetic anomalies. In International Conference on Parallel Computing Technologies. pp. 355--366.

Das, S., Braun, T., Clark, A. & Wordinger, R. (2004). Gene Expression in Human Trabecular Meshwork Cells, Lamina Cribrosa Cells and Optic Nerve Head Astrocytes following exogenous BMP--4 Treatment. Investigative Ophthalmology \& Visual Science, 45(13), 4406--4406.

Braun, T., Abdulkawy, H., Brown, B., Davis, S., O'Leary, B., Ritchison, J., Scheetz, T., Sheffield, V., Casavant, T. & Stone, E. (2004). Inferring Pathogenicity to Prioritize Candidate Disease--Causing Sequence Variations. Investigative Ophthalmology \& Visual Science, 45(13), 2441--2441.

Stone, E. M., Braun, T. A., Russell, S. R., Kuehn, M. H., Lotery, A. J., Moore, P. A., Eastman, C. G., Casavant, T. L. & Sheffield, V. C. (2004). Missense variations in the fibulin 5 gene and age-related macular degeneration. N Engl J Med, 351(4), 346-353. PMID: 15269314.00.

Scheetz, T. E., Trivedi, N., Roberts, C. A., Kucaba, T., Berger, B., Robinson, N. L., Birkett, C. L., Gavin, A. J., O'Leary, B., Braun, T. A., Bonaldo, M. F., Robinson, J. P., Sheffield, V. C., Soares, M. B. & Casavant, T. L. (2003). ESTprep: preprocessing cDNA sequence reads. Bioinformatics, 19(11), 1318-1324. DOI: 10.1093/bioinformatics/btg159.

Braun, T., Scheetz, T., Abdulkawy, H., Brown, B., Davis, S., O'Leary, B., Ritchison, J., Sutphin, R., Shankar, S., Sheffield, V. & others, (2003). Quantitatively prioritizing candidate disease gene sequences using annotation. In AMERICAN JOURNAL OF HUMAN GENETICS. (Vols. 73). (5), pp. 420--420.

Mykytyn, K., Nishimura, D. Y., Searby, C. C., Shastri, M., Yen, H. J., Beck, J. S., Braun, T., Streb, L. M., Cornier, A. S., Cox, G. F., Fulton, A. B., Carmi, R., Luleci, G., Chandrasekharappa, S. C., Collins, F. S., Jacobson, S. G., Heckenlively, J. R., Weleber, R. G., Stone, E. M. & Sheffield, V. C. (2002). Identification of the gene (BBS1) most commonly involved in Bardet-Biedl syndrome, a complex human obesity syndrome. Nature Genetics, 31(4), 435-438.

Braun, T. A., Scheetz, T., Webster, G. L. & Casavant, T. L. (2001). Mining biological databases for candidate disease genes. In Commercial Applications for High-Performance Computing. (Vols. 4528). pp. 169--181.

Wassink, T., Piven, J., Vieland, V., Juang, J., Swiderski, R., Pietila, J., Searby, C., Braun, T., Beck, G., Folstein, S. & others, (2001). WNT2 and autism. In AMERICAN JOURNAL OF HUMAN GENETICS. (Vols. 69). (4), pp. 550--550.

Braun, T. A. (2001). A software tool architecture to assist disease gene identification. The University of Iowa.

Barrett, S., Beck, J., Bernier, R., Bisson, E., Braun, T., Casavant, T., Childress, D., Folstein, S., Garcia, M., Gardiner, M. & others, (2001). An autosomal genomic screen for autism (vol 88, pg 609, 1999). AMERICAN JOURNAL OF MEDICAL GENETICS, 105(8), 805--+.

Braun, T., Scheetz, T., Mykytyn, K., Nishimura, D., Casavant, T. & Sheffield, V. (2001). Applying computational methods to search genomic sequence to identify candidate disease genes and novel sequence characteristics. In AMERICAN JOURNAL OF HUMAN GENETICS. (Vols. 69). (4), pp. 219--219.

Wang, K., Braun, T. & Sheffield, V. (2000). A novel method for estimation of short tandem repeat polymorphic marker allele frequencies from pooled DNA samples. In AMERICAN JOURNAL OF HUMAN GENETICS. (Vols. 67). (4), pp. 336--336.

Braun, T., Casavant, T. & Sheffield, V. (2000). Disease-gene discovery pipeline. In AMERICAN JOURNAL OF HUMAN GENETICS. (Vols. 67). (4), pp. 255--255.

Rai, V., Amir, R., Van Den Veyver, I., Wan, M., Tran, C., Francke, U., Zoghbi, H., Alarcon, M., Yonan, A., Gilliam, T. & others, (1999). A genome-wide screen of 345 families for autism-susceptibility loci. Trends in Molecular Sciences, 3(1), 185--188.

Casavant, T. L., Scheetz, T. E., Braun, T. A., Munn, K. J. & Kaliannan, S. (1999). A parallel/distributed architecture for hierarchically heterogeneous web-based cooperative applications. In International Conference on High-Performance Computing and Networking. pp. 391--401.

Scheetz, T. E., Braun, T. A., Munn, K. J., Stone, E. M., Sheffield, V. C. & Casavant, T. L. (1998). GenoMap: A distributed system for unifying genotyping and genetic linkage analysis1. Parallel Computing, 24(9-10), 1567--1592.

Dietz, R. D., Casavant, T. L., Scheetz, T. E., Braun, T. A. & Andersland, M. S. (1997). Modeling the impact of run-time uncertainty on optimal computation scheduling using feedback. In icpp. pp. 481.

Dietz, R. D., Casavant, T. L., Andersland, M. S., Braun, T. A. & Scheetz, T. E. (1997). The use of feedback in scheduling parallel computations. In Parallel Algorithms/Architecture Synthesis, 1997. Proceedings., Second Aizu International Symposium. pp. 124--132.

Dietz, R. D., Casavant, T. L., Scheetz, T. E., Braun, T. A. & Andersland, M. S. (1997). Using run-time uncertainty to robustly schedule parallel computation. In International Conference on Parallel Computing Technologies. pp. 13--24.

Scheetz, T. E., Gannon, J. A., Dietz, R. D., Braun, T. A., Casavant, T. L. & Andersland, M. S. (1996). Accounting for Uncertainty in the Recovery of Traces for Parallel Computing Systems. MATHEMATICAL RESEARCH, 96, 206--213.

Scheetz, T. E., Braun, T. A., Casavant, T. L., Gannon, J., Andersland, M. & Dietz, R. D. (1995). E ectiveness of Software Trace Recovery Techniques for Current Parallel Architectures,". In International Conference on High Performance Computing, New Delhi, India.

Dietz, R. D., Braun, T. A., Scheetz, T. E., Casavant, T. L. & Andersland, M. S. (1995). Feedback-Enhanced Optimization of Static Scheduling for Parallel Computer Systems.

Braun, T. A. (1995). Quantitative models for variable monitoring intrusion delays in parallel architectures. University of Iowa.

Andersland, M. S., Casavant, T. L., Braun, T. A., Dietz, R. D. & Scheetz, T. E. (1995). Using accurate trace feedback for monitoring and performance tuning of parallel computing systems,". TR-ECE-95-706, July.

Albert, H., Armstrong, D., Auletta, F., Aurbach, G., Baker, T., Barnea, A., Bartter, F., Bates, R., Bauminger, S., Beck, J. & others, (1985). List of Contributors and Discussants. Economics and Philosophy, 7, 283.

Walters, J. D., Casavant, T. L., Robinson, J. P., Bair, T. B., Braun, T. A. & Scheetz, T. E. A Multi-Granularity Parallel Approach to the Analysis of Evolutionary History Using Genomic Resources.

Casavant, T. L., Scheetz, T. E., Braun, T. A., Munn, K. J. & Kaliannan, S. An illustration of a Parallel/Distributed Architecture for Hierarchically Heterogeneous Web-Based Cooperative Applications. University of Iowa, Technical Report TR-ECE-981213, http://www. eng. uiowa. edu/\~ tomc/papers/genomapLong. tar. gz Google Scholar.

Casavant, T. L., Scheetz, T. E., Braun, T. A., Munn, K. J. & Kaliannan, S. GenoMap: A Web-Based Distributed Processing System for the Management and Analysis of Sensitive Genetic Information to Identify Specific Gene Loci.

Muzi, M., O'Sullivan, F., Mankoff, D. A., Doot, R. K., Kinahan, P. E., van der Heide, Uulke A,, Houweling, A. C., Groenendaal, G., Beets-Tan, R. G., Lambin, P. & others, Quantitative Imaging in Cancer.