Wallace L. Alward, MD

Portrait
Director, Glaucoma Service
Vice-Chair, Ophthalmology
Frederick C. Blodi Chair in Ophthalmology
Professor of Ophthalmology and Visual Sciences

Contact Information

Primary Office
11190C PFP
Iowa City, IA 52242
319-356-2228

Education

AB, Biology, Kenyon College
MD, Medicine, Ohio State University
Internship, General Surgery, University Hospitals of Pittsburgh
Resident, Chief Resident, Ophthalmology, University of Louisville
Resident, Ophthalmology, University of Louisville
Fellow, Glaucoma, Bascom Palmer Eye Institute, University of Miami

Licensure and Certifications

ABO Certification - American Board of Ophthalmology
State of Florida Medical License (inactive)
State of Kentucky Medical License (inactive)
State of Alaska Medical License (Inactive)
NBME Diplomate - National Board of Medical Examiners

Center, Program and Institute Affiliations

Carver Family Center for Macular Degeneration, Institute for Vision Research

Research Summary

Dr. Alward is primarily a glaucoma clinician. His areas of research interest include pigmentary glaucoma, combined glaucoma and cataract surgery, normal tension glaucoma, and gonioscopy. The major focus of his research over the last many years has been the molecular genetics of glaucoma. In collaboration with Edwin Stone and Val Sheffield, Dr. Alward was part of the team that described the first gene for primary open angle glaucoma. He was involved in the the discovery of the myocilin gene for primary open angle glaucoma, the PITX2 and FOXC1 genes for Axenfeld-Rieger syndrome and the TBK1 gene for normal tension glaucoma.

Publications

Provencher, L. M., Carter, P. C. & Alward, W. L. (2018). Idiopathic Bilateral Profound Hypotony in an Unknown Progressive Neurodegenerative Disorder. (reply). Journal of glaucoma, 27(1), e30. PMID: 28984717.

DeLuca, A. P., Alward, W. L., Liebmann, J., Ritch, R., Kawase, K., Kwon, Y. H., Robin, A. L., Stone, E. M., Scheetz, T. E. & Fingert, J. H. (2017). Genomic Organization of TBK1 Copy Number Variations in Glaucoma Patients. Journal of glaucoma, 26(12), 1063-1067. PMID: 28984711.

Janson, B. J., Alward, W. L., Kwon, Y. H., Bettis, D. I., Fingert, J. H., Provencher, L. M., Goins, K. M., Wagoner, M. D. & Greiner, M. A. (2017). Glaucoma-associated corneal endothelial cell damage: A review. Survey of ophthalmology. PMID: 29146208.

Provencher, L. M., Carter, K. D., Nerad, J. A. & Alward, W. L. (2017). Upper Eyelid Splitting to Facilitate the Insertion of Glaucoma Drainage Devices. Journal of glaucoma, 26(11), e249-e251. PMID: 28930886.

Provencher, L. M., Shriver, E. M. & Alward, W. L. (2017). Ptosis Masquerading as Progression of Severe Glaucoma. JAMA ophthalmology, 135(9), e172788. PMID: 28910451.

Lewis, C., Hedberg-Buenz, A., DeLuca, A. P., Stone, E. M., Alward WLM, & Fingert, J. H. (2017). Primary Congenital and Developmental Glaucomas. Human molecular genetics, 26(R1), R28-R36. PMID: 28549150.

Guo, Z., Kwon, Y. H., Lee, K., Wang, K., Wahle, A., Alward, W. L., Fingert, J. H., Bettis, D. I., Johnson, C. A., Garvin, M. K., Sonka, M. & Abràmoff, M. D. (2017). Optical Coherence Tomography Analysis Based Prediction of Humphrey 24-2 Visual Field Thresholds in Patients With Glaucoma. Investigative ophthalmology & visual science, 58(10), 3975-3985. PMID: 28796875.

Wang, X., Mudie, L. I., Baskaran, M., Cheng, C. Y., Alward, W. L., Friedman, D. S. & Brady, C. J. (2017). Crowdsourcing to Evaluate Fundus Photographs for the Presence of Glaucoma. Journal of glaucoma, 26(6), 505-510. PMID: 28319525.

Provencher, L. M., Carter, P. C. & Alward, W. L. (2017). Idiopathic Bilateral Profound Hypotony in an Unknown Progressive Neurodegenerative Disorder. Journal of glaucoma, 26(5), e168-e170. PMID: 28221333.

Simpson, A., Avdic, A., Roos, B. R., DeLuca, A., Miller, K., Schnieders, M. J., Scheetz, T. E., Alward, W. L. & Fingert, J. H. (2017). LADD syndrome with glaucoma is caused by a novel gene. Molecular vision, 23, 179-184. PMID: 28400699.

Alward, W. L. (2017). Sunshine Has Darkened my Worldview. (Vols. 175). pp. xii-xiii. American journal of ophthalmology. PMID: 28088286.

Elshatory, Y. M., Gauger, E. H., Kwon, Y. H., Alward, W. L., Boldt, H. C., Russell, S. R. & Mahajan, V. B. (2016). Management of Pediatric Aphakic Glaucoma With Vitrectomy and Tube Shunts. Journal of pediatric ophthalmology and strabismus, 53(6), 339-343. PMID: 27668871.

Alward, W. L. (2016). The Red Badge. Ophthalmology, 123(9), S30-S31. DOI: 10.1016/j.ophtha.2016.06.013.

Goins, K. M., Kitzmann, A. S., Greiner, M. A., Kwon, Y. H., Alward, W. L., Ledolter, J. & Wagoner, M. D. (2016). Boston Type 1 Keratoprosthesis: Visual Outcomes, Device Retention, and Complications. Cornea, 35(9), 1165-74. PMID: 27191675.

Risma, J. M., Tehrani, S., Wang, K., Fingert, J. H., Alward, W. L. & Kwon, Y. H. (2016). The Utility of Diaton Tonometer Measurements in Patients With Ocular Hypertension, Glaucoma, and Glaucoma Tube Shunts. Journal of Glaucoma, 25(8), 643-647. PMID: 26950582.

Fingert, J. H., Robin, A. L., Scheetz, T. E., Kwon, Y. H., Liebmann, J. M., Ritch, R. & Alward, W. L. (2016). Tank-Binding Kinase 1 (TBK1) Gene and Open-Angle Glaucomas (An American Ophthalmological Society Thesis). Transactions of the American Ophthalmological Society, 114, T6. PMID: 27881886.

Scheetz, T. E., Roos, B. R., Solivan-Timpe, F., Miller, K., DeLuca, A. P., Stone, E. M., Kwon, Y. H., Alward, W. L., Wang, K. & Fingert, J. H. (2016). SQSTM1 Mutations and Glaucoma. PloS one, 11(6), e0156001. PMID: 27275741.

Clark, T. J., Rao, K., Quinn, C. D., Batlle, J. F., Alward, W. L., Wester, S. T. & Shriver, E. M. (2016). A Vector Force Model of Upper Eyelid Position in the Setting of a Trabeculectomy Bleb. Ophthalmic Plastic & Reconstructive Surgery, 32(2), 127-32. PMID: 25794022.

Haugsdal, J. M., Goins, K. M., Greiner, M. A., Kwon, Y. H., Alward, W. L. & Wagoner, M. D. (2016). Boston type 1 keratoprosthesis for primary congenital glaucoma. British Journal of Ophthalmology, 100(3), 328-31. PMID: 26206789.

Aponte, E. P., Ball, D. C. & Alward, W. L. (2016). Iridocorneal Endothelial Syndrome in a 14-Year-Old Male. Journal of Glaucoma, 25(2), e115-e116. PMID: 26035422.

Phillips, D. L., Goins, K. M., Greiner, M. A., Alward, W. L., Kwon, Y. H. & Wagoner, M. D. (2015). Boston Type 1 Keratoprosthesis for Iridocorneal Endothelial Syndromes. Cornea, 34(11), 1383-6. PMID: 26398156.

Ahram, D. F., Alward, W. L. & Kuehn, M. H. (2015). The genetic mechanisms of primary angle closure glaucoma. Eye (London, England), 29(10), 1251-9. PMID: 26206529.

Alward, W. L., Longmuir, S. Q., Miri, M. S., Garvin, M. K. & Kwon, Y. H. (2015). Movement of Retinal Vessels to Optic Nerve Head with Intraocular Pressure Elevation in a Child. Ophthalmology, 122(7), 1532-4. PMID: 25726092.

Aung, T., Ozaki, M., Mizoguchi, T., Allingham, R. R., Li, Z., Haripriya, A., Nakano, S., Uebe, S., Harder, J. M., Chan, A. S., Lee, M. C., Burdon, K. P., Astakhov, Y. S., Abu-Amero, K. K., Zenteno, J. C., Nilgün, Y., Zarnowski, T., Pakravan, M., Safieh, L. A., Jia, L., Wang, Y. X., Williams, S., Paoli, D., Schlottmann, P. G., Huang, L., Sim, K. S., Foo, J. N., Nakano, M., Ikeda, Y., Kumar, R. S., Ueno, M., Manabe, S., Hayashi, K., Kazama, S., Ideta, R., Mori, Y., Miyata, K., Sugiyama, K., Higashide, T., Chihara, E., Inoue, K., Ishiko, S., Yoshida, A., Yanagi, M., Kiuchi, Y., Aihara, M., Ohashi, T., Sakurai, T., Sugimoto, T., Chuman, H., Matsuda, F., Yamashiro, K., Gotoh, N., Miyake, M., Astakhov, S. Y., Osman, E. A., Al-Obeidan, S. A., Owaidhah, O., Al-Jasim, L., Shahwan, S. A., Fogarty, R. A., Leo, P., Yetkin, Y., Oguz, Ç., Kanavi, M. R., Beni, A. N., Yazdani, S., Akopov, E. L., Toh, K. Y., Howell, G. R., Orr, A. C., Goh, Y., Meah, W. Y., Peh, S. Q., Kosior-Jarecka, E., Lukasik, U., Krumbiegel, M., Vithana, E. N., Wong, T. Y., Liu, Y., Koch, A. E., Challa, P., Rautenbach, R. M., Mackey, D. A., Hewitt, A. W., Mitchell, P., Wang, J. J., Ziskind, A., Carmichael, T., Ramakrishnan, R., Narendran, K., Venkatesh, R., Vijayan, S., Zhao, P., Chen, X., Guadarrama-Vallejo, D., Cheng, C. Y., Perera, S. A., Husain, R., Ho, S. L., Welge-Luessen, U. C., Mardin, C., Schloetzer-Schrehardt, U., Hillmer, A. M., Herms, S., Moebus, S., Nöthen, M. M., Weisschuh, N., Shetty, R., Ghosh, A., Teo, Y. Y., Brown, M. A., Lischinsky, I., Crowston, J. G., Coote, M., Zhao, B., Sang, J., Zhang, N., You, Q., Vysochinskaya, V., Founti, P., Chatzikyriakidou, A., Lambropoulos, A., Anastasopoulos, E., Coleman, A. L., Wilson, M. R., Rhee, D. J., Kang, J. H., May-Bolchakova, I., Heegaard, S., Mori, K., Alward, W. L., Jonas, J. B., Xu, L., Liebmann, J. M., Chowbay, B., Schaeffeler, E., Schwab, M., Lerner, F., Wang, N., Yang, Z., Frezzotti, P., Kinoshita, S., Fingert, J. H., Inatani, M., Tashiro, K., Reis, A., Edward, D. P., Pasquale, L. R., Kubota, T., Wiggs, J. L., Pasutto, F., Topouzis, F., Dubina, M., Craig, J. E., Yoshimura, N., Sundaresan, P., John, S. W., Ritch, R., Hauser, M. A. & Khor, C. C. (2015). Corrigendum: a common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. (Vols. 47). (6), pp. 689. Nature genetics. PMID: 26018902.

Aung, T., Ozaki, M., Mizoguchi, T., Allingham, R. R., Li, Z., Haripriya, A., Nakano, S., Uebe, S., Harder, J. M., Chan, A. S., Lee, M. C., Burdon, K. P., Astakhov, Y. S., Abu-Amero, K. K., Zenteno, J. C., Nilgün, Y., Zarnowski, T., Pakravan, M., Safieh, L. A., Jia, L., Wang, Y. X., Williams, S., Paoli, D., Schlottmann, P. G., Huang, L., Sim, K. S., Foo, J. N., Nakano, M., Ikeda, Y., Kumar, R. S., Ueno, M., Manabe, S., Hayashi, K., Kazama, S., Ideta, R., Mori, Y., Miyata, K., Sugiyama, K., Higashide, T., Chihara, E., Inoue, K., Ishiko, S., Yoshida, A., Yanagi, M., Kiuchi, Y., Aihara, M., Ohashi, T., Sakurai, T., Sugimoto, T., Chuman, H., Matsuda, F., Yamashiro, K., Gotoh, N., Miyake, M., Astakhov, S. Y., Osman, E. A., Al-Obeidan, S. A., Owaidhah, O., Al-Jasim, L., Al Shahwan, S., Fogarty, R. A., Leo, P., Yetkin, Y., Oguz, Ç., Kanavi, M. R., Beni, A. N., Yazdani, S., Akopov, E. L., Toh, K. Y., Howell, G. R., Orr, A. C., Goh, Y., Meah, W. Y., Peh, S. Q., Kosior-Jarecka, E., Lukasik, U., Krumbiegel, M., Vithana, E. N., Wong, T. Y., Liu, Y., Koch, A. E., Challa, P., Rautenbach, R. M., Mackey, D. A., Hewitt, A. W., Mitchell, P., Wang, J. J., Ziskind, A., Carmichael, T., Ramakrishnan, R., Narendran, K., Venkatesh, R., Vijayan, S., Zhao, P., Chen, X., Guadarrama-Vallejo, D., Cheng, C. Y., Perera, S. A., Husain, R., Ho, S. L., Welge-Luessen, U. C., Mardin, C., Schloetzer-Schrehardt, U., Hillmer, A. M., Herms, S., Moebus, S., Nöthen, M. M., Weisschuh, N., Shetty, R., Ghosh, A., Teo, Y. Y., Brown, M. A., Lischinsky, I., Crowston, J. G., Coote, M., Zhao, B., Sang, J., Zhang, N., You, Q., Vysochinskaya, V., Founti, P., Chatzikyriakidou, A., Lambropoulos, A., Anastasopoulos, E., Coleman, A. L., Wilson, M. R., Rhee, D. J., Kang, J. H., May-Bolchakova, I., Heegaard, S., Mori, K., Alward, W. L., Jonas, J. B., Xu, L., Liebmann, J. M., Chowbay, B., Schaeffeler, E., Schwab, M., Lerner, F., Wang, N., Yang, Z., Frezzotti, P., Kinoshita, S., Fingert, J. H., Inatani, M., Tashiro, K., Reis, A., Edward, D. P., Pasquale, L. R., Kubota, T., Wiggs, J. L., Pasutto, F., Topouzis, F., Dubina, M., Craig, J. E., Yoshimura, N., Sundaresan, P., John, S. W., Ritch, R., Hauser, M. A. & Khor, C. C. (2015). A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. Nature genetics, 47(4), 387-92. PMID: 25706626.

Hazlewood, R. J., Roos, B. R., Solivan-Timpe, F., Honkanen, R. A., Jampol, L. M., Gieser, S. C., Meyer, K. J., Mullins, R. F., Kuehn, M. H., Scheetz, T. E., Kwon, Y. H., Alward, W. L., Stone, E. M. & Fingert, J. H. (2015). Heterozygous triplication of upstream regulatory sequences leads to dysregulation of matrix metalloproteinase 19 in patients with cavitary optic disc anomaly. Human mutation, 36(3), 369-78. PMID: 25581579.

Alward, W. L. (2015). Gonioscopy.org – A website to teach gonioscopy through the use of videography.

Alward, W. L. (2015). Iowa Glaucoma Curriculum.

Khorram, D., Choi, M., Roos, B. R., Stone, E. M., Kopel, T., Allen, R., Alward, W. L., Scheetz, T. E. & Fingert, J. H. (2015). Novel TMEM98 mutations in pedigrees with autosomal dominant nanophthalmos. Molecular vision, 21, 1017-23. PMID: 26392740.

Tandon, A., Alward, W. L. (2015). The centennial of modern gonioscopy. Ophthalmologica, 233(1), 58-9. PMID: 25427974.

Shareef, S., Alward, W., Crandall, A., Vold, S. & Ahmed, I. (2014). Intra-operative gonioscopy: a key to successful angle surgery. Expert Review of Ophthalmology, 9(6), 515-527. DOI: 10.1586/17469899.2014.973022.

Ward, M. S., Goins, K. M., Greiner, M. A., Kitzmann, A. S., Sutphin, J. E., Alward, W. L., Greenlee, E. C., Kwon, Y. H., Zimmerman, M. B. & Wagoner, M. D. (2014). Graft Survival Versus Glaucoma Treatment After Penetrating or Descemet Stripping Automated Endothelial Keratoplasty. Cornea, 33(8), 785-89. PMID: 24915017.

Risma, T. B., Alward, W. L. (2014). Successful Long-term Management of Iris Flocculi and Miosis in a Patient With a Strong Family History of Thoracic Aortic Aneurysms and Dissections Associated With an MYH11 Mutation. JAMA ophthalmology, 132(6), 778-80. PMID: 24921172.

Tandon, A., Tehrani, S., Greiner, M. A., Fingert, J. H. & Alward, W. L. (2014). Thin Central Corneal Thickness and Early-Onset Glaucoma in Lacrimo-auriculo-dento-digital Syndrome. JAMA ophthalmology, 132(6), 782-84. PMID: 24921174.

Fingert, J. H., Burden, J. H., Wang, K., Kwon, Y. H., Alward, W. L. & Anderson, M. G. (2013). Circumferential Iris Transillumination Defects in Exfoliation Syndrome. Journal of glaucoma, 22(7), 555-8. PMID: 22525123.

Seo, S., Solivan-Timple, F., Roos, B. R., Robin, A. L., Stone, E. M., Young, Y. H., Alward, W. L. & Fingert, J. H. (2013). Identification of proteins that interact with TANK binding kinase 1 and testing for mutations associated with glaucoma. Curr Eye Res, 38(2), 310-5. PMID: 23286385.

Hong, E. S., Burden, J. H. & Alward, W. L. (2013). Intralesional ethanol for an unresectable epithelial inclusion cyst. JAMA Ophthlamol, 131(2), 262-3. PMID: 23411902.

Alward, W. L. (2013). An Artist's Perspective on the Eye - Paintings by J. McGuinness Myers. American Journal of Ophthalmology, 155(2), 412.e3. DOI: 10.1016/j.ajo.2012.12.002.

Scheetz, T. E., Fingert, J. H., Wang, K., Kuehn, M. H., Knudtson, K. L., Alward, W. L., Boldt, H. C., Russell, S. R., Folk, J. C., Casavant, T. L., Braun, T. A., Clark, A. F., Stone, E. M. & Sheffield, V. C. (2013). A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci. PLoS One, 8(3), e58657. PMID: 23536807.

Fingert, J. H., Roos, B. R., Solivan-Timpe, F., Miller, K. A., Oetting, T. A., Wang, K., Kwon, Y. H., Scheetz, T. E., Stone, E. M. & Alward, W. L. (2012). Analysis of ASB10 variants in open angle glaucoma. Human molecular genetics, 21(20), 4543-8. PMID: 22798626.

Wandling, G. R., Rauen, M. P., Goins, K. M., Kitzmann, A. S., Sutphin, J. E., Kwon, Y. H., Alward, W. L. & Wagoner, M. D. (2012). Glaucoma therapy escalation in eyes with pseudophakic corneal edema after penetrating keratoplasty and Descemet's stripping automated endothelial keratoplasty. International ophthalmology, 32(1), 14-Sep. PMID: 22246622.

Mao, M., Solivan-Timpe, F., Roos, B. R., Mullins, R. F., Oetting, T. A., Kwon, Y. H., Brzeskiewicz, P. M., Stone, E. M., Alward, W. L., Anderson, M. G. & Fingert, J. H. (2012). Localization of SH3PXD2B in human eyes and detection of rare variants in patients with anterior segment diseases and glaucoma. Molecular vision, 18, 705-13. PMID: 22509100.

Tang, L., Garvin, M. K., Lee, K., Alward, W. L., Kwon, Y. H. & Abramoff, M. D. (2011). Robust multiscale stereo matching from fundus images with radiometric differences. IEEE Transactions on Pattern Analysis and Machine Intelligence, 33(11), 2245-2258. DOI: 10.1109/TPAMI.2011.69.

Fingert, J. H., Robin, A. L., Stone, J. L., Roos, B. R., Davis, L. K., Scheetz, T. E., Bennett, S. R., Wassink, T. H., Kwon, Y. H., Alward, W. L., Mullins, R. F., Sheffield, V. C. & Stone, E. M. (2011). Copy number variations on chromosome 12q14 in patients with normal tension glaucoma. Human molecular genetics, 20(12), 2482-94. PMID: 21447600.

Alward, W. L. (2011). A history of gonioscopy. Optometry and vision science, 88(1), 29-35. PMID: 20966801.

Kuehn, M. H., Wang, K., Roos, B., Stone, E. M., Kwon, Y. H., Alward, W. L., Mullins, R. F. & Fingert, J. H. (2011). Chromosome 7q31 POAG locus: ocular expression of caveolins and lack of association with POAG in a US cohort. Mol Vis, 17, 430-5. PMID: 21321670.

Davis, L. K., Meyer, K. J., Schindler, E. I., Beck, J. S., Rudd, D. S., Grundstad, A. J., Scheetz, T. E., Braun, T. A., Fingert, J. H., Alward, W. L., Kwon, Y. H., Folk, J. C., Russell, S. R., Wassink, T. H., Sheffield, V. C. & Stone, E. M. (2011). Copy number variations and primary open-angle glaucoma. Investigative ophthalmology & visual science, 52(10), 7122-33. PMID: 21310917.

Meyer, K. J., Davis, L. K., Schindler, E. I., Beck, J. S., Rudd, D. S., Grundstad, A. J., Scheetz, T. E., Braun, T. A., Fingert, J. H., Alward, W. L., Kwon, Y. H., Folk, J. C., Russell, S. R., Wassink, T. H., Stone, E. M. & Sheffield, V. C. (2011). Genome-wide analysis of copy number variants in age-related macular degeneration. Human genetics, 129(1), 91-100. PMID: 20981449.

Wandling, G. R., Parikh, M., Robinson, C., Pramanik, S. N., Goins, K. M., Sutphin, J. E., Alward, W. L., Greenlee, E. C., Kwon, Y. H. & Wagoner, M. D. (2010). Escalation of glaucoma therapy after deep lamellar endothelial keratoplasty. Cornea, 29(9), 991-5. PMID: 20520533.

Tang, L., Kwon, Y. H., Alward, W. L., Greenlee, E. C., Lee, K., Garvin, M. K. & Abramoff, M. D. (2010). 3D reconstruction of the optic nerve head using stereo fundus images for computer-aided diagnosis of glaucoma. Proceedings of the SPIE, 7624, 76243D.

Fingert, J. H., Alward, W. L., Wang, K., Yorio, T. & Clark, A. F. (2010). Assessment of SNPs associated with the human glucocorticoid receptor in primary open-angle glaucoma and steroid responders. Molecular vision, 16, 596-601. PMID: 20376328.

Parikh, M., Alward, W. (2010). Axenfeld-Rieger Syndrome and Peters anomaly (Chapter 58). In J. H. Krachmer , M. Mannis , E. J. Holland (Eds.) Cornea. (3rd ed), pp. 655-65. St Louis, MO: Mosby.

AbrÌÊmoff, M. D., Lee, K., Niemeijer, M., Alward, W. L., Greenlee, E. C., Garvin, M. K., Sonka, M. & Kwon, Y. H. (2009). Automated segmentation of the cup and rim from spectral domain OCT of the optic nerve head. Investigative Opthalmology & Visual Science, 50(12), 5778-84. PMID: 19608531.

Kwon, Y. H., Adix, M., Zimmerman, M. B., Piette, S., Greenlee, E. C., Alward, W. L. & AbrÌÊmoff, M. D. (2009). Variance owing to observer, repeat imaging, and fundus camera type on cup-to-disc ratio estimates by stereo planimetry. Journal of glaucoma, 18(4), 305-10. PMID: 19365196.

Trantow, C. M., Mao, M., Petersen, G. E., Alward, E. M., Alward, W. L., Fingert, J. H. & Anderson, M. G. (2009). LYST mutation in mice recapitulates iris defects of human exfoliation syndrome. Investigative ophthalmology & visual science, 50(3), 1205-14. PMID: 19029039.

Kwon, Y. H., Fingert, J. H., Kuehn, M. H. & Alward, W. L. (2009). Primary open-angle glaucoma. The New England journal of medicine, 360(11), 1113-24. PMID: 19279343.

Longmuir, R. A., Fingert, J. H. & Alward, W. (2009). Inflammatory Glaucoma (Chapter 54D). In W. Tasman , A. F. Jacqer (Eds.) Duane's Clinical Ophthalmology. Philadelphia, PA: Lippincott Williams & Wilkins.

Alward, W. L. (2009). How I choose a prostaglandin analogue. American journal of ophthalmology, 147(1), 1-2. PMID: 19100349.

Fingert, J. H., Alward, W. L., Kwon, Y. H., Wang, K., Streb, L. M., Sheffield, V. C. & Stone, E. M. (2007). LOXL1 mutations are associated with exfoliation syndrome in patients from the midwestern United States. American journal of ophthalmology, 144(6), 974-975. PMID: 18036875.

Hewitt, A. W., Poulsen, J. P., Alward, W. L., Bennett, S. L., Budde, W. M., Cooper, R. L., Craig, J. E., Fingert, J. H., Foster, P. J. & Garway-Heath, D. F. (2007). Heritable features of the optic disc: a novel twin method for determining genetic significance. Investigative ophthalmology & visual science, 48(6), 2469-75. PMID: 17525172.

Dinn, R. B., Zimmerman, M. B., Shuba, L. M., Doan, A. P., Maley, M. K., Greenlee, E. C., Alward, W. L. & Kwon, Y. H. (2007). Concordance of diurnal intraocular pressure between fellow eyes in primary open-angle glaucoma. Ophthalmology, 114(5), 915-20. PMID: 17467528.

Shuba, L. M., Doan, A. P., Maley, M. K., Zimmerman, M. B., Dinn, R. B., Greenlee, E. C., Alward, W. L. & Kwon, Y. H. (2007). Diurnal fluctuation and concordance of intraocular pressure in glaucoma suspects and normal tension glaucoma patients. Journal of glaucoma, 16(3), 307-12. PMID: 17438425.

Honkanen, R. A., Jampol, L. M., Fingert, J. H., Moore, M. D., Taylor, C. M., Stone, E. M. & Alward, W. L. (2007). Familial cavitary optic disk anomalies: clinical features of a large family with examples of progressive optic nerve head cupping. American journal of ophthalmology, 143(5), 788-794. PMID: 17362864.

AbrÌÊmoff, M. D., Alward, W. L., Greenlee, E. C., Shuba, L., Kim, C. Y., Fingert, J. H. & Kwon, Y. H. (2007). Automated segmentation of the optic disc from stereo color photographs using physiologically plausible features. Investigative Ophthalmology & Visual Science, 48(4), 1665-73. PMID: 17389498.

Fingert, J. H., Alward, W. L., Kwon, Y. H., Shankar, S. P., Andorf, J. L., Mackey, D. A., Sheffield, V. C. & Stone, E. M. (2007). No association between variations in the WDR36 gene and primary open-angle glaucoma. Archives of ophthalmology, 125(3), 434-6. PMID: 17353431.

Honkanen, R., Alward, W. L. & Cossari, A. J. (2006). Progressive iris changes in a case of Axenfeld-Rieger syndrome. Archives of ophthalmology, 124(12), 1793. PMID: 17159049.

Kuehn, M. H., Kim, C. Y., Ostojic, J., Bellin, M., Alward, W. L., Stone, E. M., Sakaguchi, D. S., Grozdanic, S. D. & Kwon, Y. H. (2006). Retinal synthesis and deposition of complement components induced by ocular hypertension. Experimental eye research, 83(3), 620-8. PMID: 16677633.

Fingert, J. H., Kwon, Y. H., Moore, P. A., Johnston, R. M., Kim, K. Y., Sheffield, V. C., Alward, W. L. & Stone, E. M. (2006). The C677T variant in the methylenetetrahydrofolate reductase gene is not associated with disease in cohorts of pseudoexfoliation glaucoma and primary open-angle glaucoma patients from Iowa. Ophthalmic genetics, 27(2), 39-41. PMID: 16754204.

Maciolek, N. L., Alward, W. L., Murray, J. C., Semina, E. V. & McNally, M. T. (2006). Analysis of RNA splicing defects in PITX2 mutants supports a gene dosage model of Axenfeld-Rieger syndrome. BMC medical genetics, 7, 59. PMID: 16834779.

Alward, W. (2005). Axenfeld-Rieger Syndrome and Peters anomaly (Chapter 63). In J. H. Krachmer , M. Mannis , E. H. Holland (Eds.) Cornea. (2nd ed) St Louis, MO: Mosby.

Reistad, C. E., Shields, M. B., Campbell & et al (2005). The influence of peripheral iridotomy on the intraocular pressure course of patients with pigmentary glaucoma. Journal of Glaucoma, 14, 255-259. PMID: 15990602.

Alward, W. L. (2004). Macular degeneration and glaucoma-like optic nerve head cupping. American journal of ophthalmology, 138(1), 135-6. PMID: 15234293.

Grassi, M. A., Alward, W. L., Verdick, R. L., Langlow, E. P. & Kwon, Y. H. (2004). Atypical pigment dispersion syndrome in a child. American journal of ophthalmology, 137(4), 753-6. PMID: 15059719.

Alward, W. (2004). Should glaucoma patients undergo genetic testing?. In R. Susanna (Eds.) Important Questions About Glaucoma. Sao Paolo: Cultura Medica.

Alward, W. L., Kwon, Y. H., Kawase, K., Craig, J. E., Hayreh, S. S., Johnson, A. T., Khanna, C. L., Yamamoto, T., Mackey, D. A. & Roos, B. R. (2003). Evaluation of optineurin sequence variations in 1,048 patients with open-angle glaucoma. American journal of ophthalmology, 136(5), 904-10. PMID: 14597044.

Kwon, Y. H., Kim, Y. I., Pereira, M. L., Montague, P. R., Zimmerman, M. B. & Alward, W. L. (2003). Rate of optic disc cup progression in treated primary open-angle glaucoma. Journal of glaucoma, 12(5), 409-16. PMID: 14520149.

Honkanen, R. A., Nishimura, D. Y., Swiderski, R. E., Bennett, S. R., Hong, S., Kwon, Y. H., Stone, E. M., Sheffield, V. C. & Alward, W. L. (2003). A family with Axenfeld-Rieger syndrome and Peters Anomaly caused by a point mutation (Phe112Ser) in the FOXC1 gene. American journal of ophthalmology, 135(3), 368-75. PMID: 12614756.

Alward, W. L. (2003). Biomedicine. A new angle on ocular development. Science (New York, N.Y.), 299, 1527-1528. PMID: 12624251.

Anderson, D. R., Drance, S. M., Schulzer, M. (2003). Factors that predict the benefit of lowering intraocular pressure in normal tension glaucoma. American Journal of Ophthalmology, 136, 820-829.

Alward, W. L. (2003). The OPA1 gene and optic neuropathy. British Journal of Ophthalmology, 87, 2-3. PMID: 12488251.

Graul, T. A., Kwon, Y. H., Zimmerman, M. B., Kim, C. S., Sheffield, V. C., Stone, E. M. & Alward, W. L. (2002). A case-control comparison of the clinical characteristics of glaucoma and ocular hypertensive patients with and without the myocilin Gln368Stop mutation. American journal of ophthalmology, 134(6), 884-90. PMID: 12470758.

Pereira, M. L., Kim, C. S., Zimmerman, M. B., Alward, W. L., Hayreh, S. S. & Kwon, Y. H. (2002). Rate and pattern of visual field decline in primary open-angle glaucoma. Ophthalmology, 109(12), 2232-40. PMID: 12466164.

Fingert, J. H., Stone, E. M., Sheffield, V. C. & Alward, W. L. (2002). Myocilin glaucoma. Survey of ophthalmology, 47(6), 547-61. PMID: 12504739.

Alward, W. L., Kwon, Y. H., Khanna, C. L., Johnson, A. T., Hayreh, S. S., Zimmerman, M. B., Narkiewicz, J., Andorf, J. L., Moore, P. A. & Fingert, J. H. (2002). Variations in the myocilin gene in patients with open-angle glaucoma. Archives of ophthalmology, 120(9), 1189-97. PMID: 12215093.

Bruno, C. A., Alward, W. L. (2002). Gonioscopy in primary angle closure glaucoma. Seminars in ophthalmology, 17(2), 59-68. PMID: 15513458.

Graul, T. A., Kim, C. S., Alward, W. L. & Kwon, Y. H. (2002). Progressive axial myopia in a juvenile patient with traumatic glaucoma. American journal of ophthalmology, 133(5), 700-2. PMID: 11992870.

Borges, A. S., Susanna, R., Carani, J. C., Betinjane, A. J., Alward, W. L., Stone, E. M., Sheffield, V. C. & Nishimura, D. Y. (2002). Genetic analysis of PITX2 and FOXC1 in Rieger Syndrome patients from Brazil. Journal of glaucoma, 11(1), 51-6. PMID: 11821690.

Kawase, C., Kawase, K., Taniguchi, T., Sugiyama, K., Yamamoto, T., Kitazawa, Y., Alward, W. L., Stone, E. M., Nishimura, D. Y. & Sheffield, V. C. (2001). Screening for mutations of Axenfeld-Rieger syndrome caused by FOXC1 gene in Japanese patients. Journal of glaucoma, 10(6), 477-82. PMID: 11740218.

Alward, W. L. (2001). Additive efficacy of unoprostone isopropyl 0.12% (rescula) to latanoprost 0.005%. American journal of ophthalmology, 132(3), 449-51. PMID: 11554384.

Kwon, Y. H., Kim, C. S., Zimmerman, M. B., Alward, W. L. & Hayreh, S. S. (2001). Rate of visual field loss and long-term visual outcome in primary open-angle glaucoma. American journal of ophthalmology, 132(1), 47-56. PMID: 11438053.

Clark, A. F., Kawase, K., English-Wright, S., Lane, D., Steely, H. T., Yamamoto, T., Kitazawa, Y., Kwon, Y. H., Fingert, J. H., Swiderski, R. E., Mullins, R. F., Hageman, G. S., Alward, W. L., Sheffield, V. & Stone, E. M. (2001). Expression of the glaucoma gene myocilin (MYOC) in the human optic nerve head. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 15(7), 1251-3. PMID: 11344104.

Nishimura, D. Y., Searby, C. C., Alward, W. L., Walton, D., Craig, J. E., Mackey, D. A., Kawase, K., Kanis, A. B., Patil, S. R. & Stone, E. M. (2001). A spectrum of FOXC1 mutations suggests gene dosage as a mechanism for developmental defects of the anterior chamber of the eye. American journal of human genetics, 68(2), 364-72. PMID: 11170889.

Kwon, Y. H., Taylor, J. M., Hong, S., Honkanen, R. A., Zimmerman, M. B., Alward, W. L. & Sutphin, J. E. (2001). Long-term results of eyes with penetrating keratoplasty and glaucoma drainage tube implant. Ophthalmology, 108(2), 272-8. PMID: 11158798.

Fingert, J. H., Clark, A. F., Craig, J. E., Alward, W. L., Snibson, G. R., McLaughlin, M., Tuttle, L., Mackey, D. A., Sheffield, V. C. & Stone, E. M. (2001). Evaluation of the myocilin (MYOC) glaucoma gene in monkey and human steroid-induced ocular hypertension. Investigative ophthalmology & visual science, 42(1), 145-52. PMID: 11133859.

Collaborative Normal-Tension Glaucoma Study Group, (2001). Natural History of Normal-Tension Glaucoma (Collaborative Normal-Tension Glaucoma Study). Ophthalmology, 108(2). PMID: 11158794.

Jacobson, N., Andrews, M., Shepard, A. R., Nishimura, D., Searby, C., Fingert, J. H., Hageman, G., Mullins, R., Davidson, B. L., Kwon, Y. H., Alward, W. L., Stone, E. M. & Sheffield, V. (2001). Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor. Human molecular genetics, 10(2), 117-25. PMID: 11152659.

Parrish, R. K., Schiffman, J. C., Feuer, W. J., Heuer, D. K. (2001). Prognosis and risk factors for early postoperative wound leaks after trabeculectomy with and without fluorouracil. American Journal of Ophthalmology, 132, 633-640.

Drance, S., Anderson, D. R., Schulzer, M. (2001). Risk factors for progression of visual field abnormalities in normal-tension glaucoma. American Journal of Ophthalmology, 131, 699-708.

Sheffield, V. C., Alward, W. & Stone, E. M. (2001). The Glaucomas. In C. R. Scriver , A. L. Beauder & S. S. Sly , D. Valle (Eds.) The Metabolic and Molecular Bases of Inherited Disease (in 4 volumes). (8th ed) New York: McGraw-Hill.

Graul, T. D., Alward, W. (2001). Uveitic Glaucoma (Chapter 54D). In W. Tasman , A. F. Jacqer (Eds.) Duane's Clinical Ophthalmology (in 6 volumes). Philadelphia, PA: Lippincott Williams & Wilkins.

Swiderski, R. E., Ross, J. L., Fingert, J. H., Clark, A. F., Alward, W. L., Stone, E. M. & Sheffield, V. C. (2000). Localization of MYOC transcripts in human eye and optic nerve by in situ hybridization. Investigative ophthalmology & visual science, 41(11), 3420-8. PMID: 11006234.

Amendt, B. A., Semina, E. V. & Alward, W. L. (2000). Rieger syndrome: a clinical, molecular, and biochemical analysis. Cellular and molecular life sciences : CMLS, 57(11), 1652-66. PMID: 11092457.

Kwon, Y. H., Hong, S., Honkanen, R. A. & Alward, W. L. (2000). Correlation of automated visual field parameters and peripapillary nerve fiber layer thickness as measured by scanning laser polarimetry. Journal of glaucoma, 9(4), 281-8. PMID: 10958600.

Alward, W. L. (2000). Axenfeld-Rieger syndrome in the age of molecular genetics. American journal of ophthalmology, 130(1), 107-15. PMID: 11004268.

Alward, W. L. (2000). The genetics of open-angle glaucoma: the story of GLC1A and myocilin. Eye (London, England), 14 ( Pt 3B), 429-36. PMID: 11026970.

Smith, R. S., Zabaleta, A., Kume, T., Savinova, O. V., Kidson, S. H., Martin, J. E., Nishimura, D. Y., Alward, W. L., Hogan, B. L. & John, S. W. (2000). Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development. Human molecular genetics, 9(7), 1021-32. PMID: 10767326.

Alward, W. L. (2000). Frequency doubling technology perimetry for the detection of glaucomatous visual field loss. American journal of ophthalmology, 129(3), 376-8. PMID: 10755955.

Alward, W., Fingert, J. H., Kwon, Y. H., Johnson, A. T., Hayreh, S. S., Sheffield, V. C. & Stone, E. M. (2000). Characterization of a large family with adult-onset primary open-angle glaucoma caused by a mutation in the GLC1A gene. In G. K. Krieglstein (Eds.) Glaucoma Update VI, Chapter 7. Berlin, Heidelberg: Springer-Verlag.

Alward, W. L. (2000). Glaucoma, The Requisites in Ophthalmology. St. Louis: Mosby, Inc..

Haynes, W. L., Alward, W. L. (1999). Combination of autologous blood injection and bleb compression sutures to treat hypotony maculopathy. Journal of glaucoma, 8(6), 384-7. PMID: 10604298.

Swiderski, R. E., Reiter, R. S., Nishimura, D. Y., Alward, W. L., Kalenak, J. W., Searby, C. S., Stone, E. M., Sheffield, V. C. & Lin, J. J. (1999). Expression of the Mf1 gene in developing mouse hearts: implication in the development of human congenital heart defects. Developmental dynamics : an official publication of the American Association of Anatomists, 216(1), 16-27. PMID: 10474162.

Oh, K. T., Alward, W. L. & Kardon, R. H. (1999). Myositis associated with a Baerveldt glaucoma implant. American journal of ophthalmology, 128(3), 375-6. PMID: 10511042.

Fingert, J. H., HÌ©on, E., Liebmann, J. M., Yamamoto, T., Craig, J. E., Rait, J., Kawase, K., Hoh, S. T., Buys, Y. M., Dickinson, J., Hockey, R. R., Williams-Lyn, D., Trope, G., Kitazawa, Y., Ritch, R., Mackey, D. A., Alward, W. L. & Sheffield, V. C. (1999). Analysis of myocilin mutations in 1703 glaucoma patients from five different populations. Human molecular genetics, 8(5), 899-905. PMID: 10196380.

Swiderski, R. E., Ying, L., Cassell, M. D., Alward, W. L., Stone, E. M. & Sheffield, V. C. (1999). Expression pattern and in situ localization of the mouse homologue of the human MYOC (GLC1A) gene in adult brain. Brain Research. Molecular Brain Research, 68(42737), 64-72. PMID: 10320784.

Haynes, W. L., Alward, W. L. (1999). Control of intraocular pressure after trabeculectomy. Survey of ophthalmology, 43(4), 345-55. PMID: 10025517.

Semina, E. V., Ferrell, R. E., Mintz-Hittner, H. A., Bitoun, P., Alward, W. L., Reiter, R. S., Funkhauser, C., Daack-Hirsch, S. & Murray, J. C. (1998). A novel homeobox gene PITX3 is mutated in families with autosomal-dominant cataracts and ASMD. Nature genetics, 19(2), 167-70. PMID: 9620774.

Nishimura, D. Y., Swiderski, R. E., Alward, W. L., Searby, C. C., Patil, S. R., Bennet, S. R., Kanis, A. B., Gastier, J. M., Stone, E. M. & Sheffield, V. C. (1998). The forkhead transcription factor gene FKHL7 is responsible for glaucoma phenotypes which map to 6p25. Nature genetics, 19(2), 140-7. PMID: 9620769.

Fingert, J. H., Ying, L., Swiderski, R. E., Nystuen, A. M., Arbour, N. C., Alward, W. L., Sheffield, V. C. & Stone, E. M. (1998). Characterization and comparison of the human and mouse GLC1A glaucoma genes. Genome research, 8(4), 377-84. PMID: 9548973.

Alward, W. L., Semina, E. V., Kalenak, J. W., HÌ©on, E., Sheth, B. P., Stone, E. M. & Murray, J. C. (1998). Autosomal dominant iris hypoplasia is caused by a mutation in the Rieger syndrome (RIEG/PITX2) gene. American journal of ophthalmology, 125(1), 98-100. PMID: 9437321.

Alward, W. L., Fingert, J. H. & Coote, M. A. (1998). Clinical Features Associated with Mutations in the Chromosome 1 Open-Angle Glaucoma Gene (GLC1A). New England Journal of Medicine, 338(15), 1022-1027. PMID: 9535666.

Semina, E. V., Reiter, R. & Leysens, N. J. (1998). Cloning and Characterizatio of a Novel Bicoid-Related Homeobox Transcription Factor Gene, REIG, Involved in Rieger Syndrome. Natural Geneticfs, 14(4), 498-505.

Fingert, J. H., Ying, L., Swiderski, R., Arbour, N., Nystuen, A., Alward, W., Sheffield, V. C. & Stone, E. M. (1998). Comparison and characterization of the human GLC1A glaucoma gene and its mouse orthologue. Investigative Ophthalmology and Visual Science, 39(Supp), S512.

Collaborative Normal-Tension Glaucoma Study Group (1998). Comparison of Glaucomatous Progression between Untreated Patients with Normal-Tension Glaucoma and Patients with Therapeutically Reduced Intraocular Pressues. American Journal of Ophthalmology, 126(4), 487-497.

Alward, W. L. (1998). Medical Management of Glaucoma. New England Journal, 339, 1298-1307. PMID: 9791148.

Collaborative Normal-Tension Glaucoma Study (1998). The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma. American Journal of Ophthalmology, 126(4), 498-505. PMID: 9780094.

McKinney, J. K., Alward, W. L. (1997). Unilateral pigment dispersion and glaucoma caused by angle recession. Archives of ophthalmology, 115(11), 1478-9. PMID: 9366689.

Hayreh, S. S., Zimmerman, M. B., Podhajsky, P. & Alward, W. L. (1997). Nonarteritic anterior ischemic optic neuropathy: role of nocturnal arterial hypotension. Archives of ophthalmology, 115(7), 942-5. PMID: 9230848.

Carlson, D. W., Alward, W. L., Barad, J. P., Zimmerman, M. B. & Carney, B. L. (1997). A randomized study of mitomycin augmentation in combined phacoemulsification and trabeculectomy. Ophthalmology, 104(4), 719-24. PMID: 9111269.

Stone, E. M., Fingert, J. H., Alward, W. L., Polansky, J. R., Nguyen, T. D., Sunden, S. L., Nishimura, D., Clark, A. F., Nystuen, A. & Nichols, B. E. (1997). Identification of a gene that causes primary open angle glaucoma. Science (New York, N.Y.), 275(5300), 668-70. PMID: 9005853.

Alward, W. (1997). Molecular genetics of glaucoma: Effects on the future of disease classification (Chapter 9). E. M. Van Buskirk , M. B. Shields (Eds.) Philadelphia, PA: Lippincott-Raven 100 Years of Progress in Glaucoma.

Semina, E. V., Reiter, R., Leysens, N. J., Alward, W. L., Small, K. W., Datson, N. A., Siegel-Bartelt, J., Bierke-Nelson, D., Bitoun, P. & Zabel, B. U. (1996). Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome. Nature genetics, 14(4), 392-399. PMID: 8944018.

Sunden, S. L., Alward, W. L., Nichols, B. E., Rokhlina, T. R., Nystuen, A., Stone, E. M. & Sheffield, V. C. (1996). Fine mapping of the autosomal dominant juvenile open angle glaucoma (GLC1A) region and evaluation of candidate genes. Genome research, 6(9), 862-9. PMID: 8889553.

Alward, W. L., Johnson, A. T., Nishimura, D. Y., Sheffield, V. C. & Stone, E. M. (1996). Molecular genetics of glaucoma: current status. Journal of glaucoma, 5(4), 276-84. PMID: 8795774.

The Fluorouracil Filtering Surgery Study Group (1996). Five-year follow-up of the Fluorouracil Filtering Surgery Study. American Journal of Ophthalmology, 121(4), 349-366. PMID: 8604728.

(1996). Five-year follow-up of the Fluorouracil Filtering Surgery Study (letter). (Vols. 122). pp. 751. American Journal of Ophthalmology.

Johnson, A. T., Alward, W., Sheffield, V. C. & Stone, E. M. (1996). Genetics and Glaucoma (Chapter 2). In R. Ritch , M. B. Shields , T. Krupin (Eds.) The Glaucomas. (2nd ed) St Louis: CV Mosby.

Alward, W. L. (1996). Marked intraocular pressure rise following autologous blood injection into a filtering bleb. Spanish edition of Archives of Ophthalmology, 7(88-89).

Alward, W. L., Ossoinig, K. C. (1996). Pigment dispersion secondary to cysts of the iris pigment epithelium. Chinese edition of Archives of Ophthalmology, 5, 98-99.

Haynes, W. L., Thompson, H. S., Johnson, A. T. & Alward, W. L. (1995). Comparison of the miotic effects of dapiprazole and dilute pilocarpine in patients with the pigment dispersion syndrome. Journal of glaucoma, 4(6), 379-85. PMID: 19920703.

Alward, W. L. (1995). Marked intraocular pressure rise following blood injection into a filtering bleb. Archives of ophthalmology, 113(10), 1232-3. PMID: 7575250.

L, H. W., Alward, W. L., Tello, C., Liebmann, J. M. & Ritch, R. (1995). Incomplete elimination of exercise-induced pigment dispersion by laser iridotomy in pigment dispersion syndrome. Ophthalmic surgery and lasers, 26(5), 484-6. PMID: 8963864.

HÌ©on, E., Sheth, B. P., Kalenak, J. W., Sunden, S. L., Streb, L. M., Taylor, C. M., Alward, W. L., Sheffield, V. C. & Stone, E. M. (1995). Linkage of autosomal dominant iris hypoplasia to the region of the Rieger syndrome locus (4q25). Human Molecular Genetics, 4(8), 1435-9. PMID: 7581385.

Haynes, W. L., Alward, W. L. (1995). Rapid visual recovery and long-term intraocular pressure control after donor scleral patch grafting for trabeculectomy-induced hypotony maculopathy. Journal of glaucoma, 4(3), 200-1. PMID: 19920669.

Carlson, D. W., Alward, W. L. & Folberg, R. (1995). Aggressive nevus of the iris with secondary glaucoma in a child. American journal of ophthalmology, 119(3), 367-8. PMID: 7872400.

Munden, P. M., Alward, W. L. (1995). Combined phacoemulsification, posterior chamber intraocular lens implantation, and trabeculectomy with mitomycin C. American journal of ophthalmology, 119(1), 20-9. PMID: 7825686.

Alward, W. L. (1995). Linkage of posterior polymorphous corneal dystrophy to 20q11. Human Molecular Genetics, 4, 485-588. PMID: 7795607.

Alward, W. L., Ossoinig, K. C. (1995). Pigment dispersion secondary to cysts of the iris pigmenjt epithelium. Archives of Ophthalmology, 113, 1574-1575. PMID: 7487635.

Campagna, J. A., Munden, P. M. & Alward, W. L. (1995). Tenon's cyst formation after trabeculectomy with mitomycin C. Ophthalmic surgery, 26(1), 57-60. PMID: 7746627.

Haynes, W. L., Alward, W. L. & McKinney, J. K. (1994). Low-energy argon laser suture lysis after trabeculectomy. American journal of ophthalmology, 117(6), 800-1. PMID: 8198165.

Hayreh, S. S., Zimmerman, M. B., Podhajsky, P. & Alward, W. L. (1994). Nocturnal arterial hypotension and its role in optic nerve head and ocular ischemic disorders. American journal of ophthalmology, 117(5), 603-24. PMID: 8172267.

Alward, W., Murray, J. C. (1994). Axenfeld-Rieger Syndrome. In J. Wiggs (Eds.) Molecular Genetics of Ocular Disorders. New York, NY: Wiley-Liss.

Alward, W. L. (1994). Color Atlas of Gonioscopy. London: Mosby-Yearbook Europe.

Haynes, W. L., Alward, W. L. & Thompson, H. S. (1994). Distortion of the pupil in patients with the pigment dispersion syndrome. Journal of glaucoma, 3(4), 329-32. PMID: 19920618.

Collaborative Normal-Tension Glaucoma Study Group (1994). Errors in the Diagnosis of Visual-Field Progression in Normal-Tension Glaucoma. Ophthalmology, 101(9), 1589-1594.

Haynes, W. L., Alward, W. L., McKinney, J. K., Munden, P. M. & Verdick, R. (1994). Quantitation of iris transillumination defects in eyes of patients with pigmentary glaucoma. Journal of glaucoma, 3(2), 106-13. PMID: 19920562.

Alward, A. L. (1994). Slide Atlas of Gonioscopy. London: Wolfe Slide Atlases.

Ritch, R., Alward, W. L. (1993). Asymmetric pigmentary glaucoma caused by unilateral angle recession. American journal of ophthalmology, 116(6), 765-6. PMID: 8250082.

Joos, K. M., Alward, W. L. & Folberg, R. (1993). Experimental endoscopic goniotomy. A potential treatment for primary infantile glaucoma. Ophthalmology, 100(7), 1066-70. PMID: 8321530.

Sheffield, V. C., Stone, E. M., Alward, W. L., Drack, A. V., Johnson, A. T., Streb, L. M. & Nichols, B. E. (1993). Genetic linkage of familial open angle glaucoma to chromosome 1q21-q31. Nature genetics, 4(1), 47-50. PMID: 8513321.

Johnson, A. T., Drack, A. V., Kwitek, A. E., Cannon, R. L., Stone, E. M. & Alward, W. L. (1993). Clinical features and linkage analysis of a family with autosomal dominant juvenile glaucoma. Ophthalmology, 100(4), 524-9. PMID: 8479711.

The Fluorouracil Filtering Surgery Study (1993). Three-Year Follow-up of the Fluorouracil Filtering Study Group. American Journal of Ophthalmology, 115(1), 82-92. PMID: 8420383.

Farrell, T. A., Alward, W. L. (1993). Fundamental of Slit Lamp Biomicroscopy. American Academy of Ophthalmology.

Murray, J. C., Bennett, S. R., Kwitek, A. E., Small, K. W., Schinzel, A., Alward, W. L., Weber, J. L., Bell, G. I. & Buetow, K. H. (1992). Linkage of Rieger syndrome to the region of the epidermal growth factor gene on chromosome 4. Nature genetics, 2(1), 46-9. PMID: 1303248.

Haynes, W. L., Johnson, A. T. & Alward, W. L. (1992). Effects of jogging exercise on patients with the pigmentary dispersion syndrome and pigmentary glaucoma. Ophthalmology, 99(7), 1096-103. PMID: 1495789.

Schulzer, M. (1992). Intraocular pressure reduction in normal-tension glaucoma patients. Ophthalmology, 99, 1468-1470.

(1992). Risk factors for suprachoroidal hemorrhage after filtering surgery. American Journal of Ophthalmology, 113(5), 501-507. PMID: 1575223.

Joos, K. M., Brown, D. M. & Alward, W. L. (1991). A multilens case. Archives of ophthalmology, 109(10), 1343-4. PMID: 1929910.

Haynes, W. L., Thompson, H. S., Kardon, R. H. & Alward, W. L. (1991). Asymmetric pigmentary dispersion syndrome mimicking Horner's syndrome. American journal of ophthalmology, 112(4), 463-4. PMID: 1928256.

Lam, B. L., Alward, W. L. & Kolder, H. E. (1991). Effect of cataract on automated perimetry. Ophthalmology, 98(7), 1066-70. PMID: 1891215.

Wolf, M. D., Alward, W. L. & Folk, J. C. (1991). Long-term visual function in acute posterior multifocal placoid pigment epitheliopathy. Archives of ophthalmology, 109(6), 800-3. PMID: 2043067.

Carlson, D. W., Alward, W. L. (1991). A placebo for mitomycin C. Ophthalmology, 100, 1343-1344. PMID: 8459992.

Alward, W. (1991). Argon laser trabeculoplasty (Chapter 13). In S. R. Sneed , T. A. Weingeist (Eds.) Practical Applications of Laser Surgery in Ophthalmology. Norwalk, CT: Appleton & Lange.

Alward, W. (1991). Laser cyclophotocoagulation (Chapter 14). In S. R. Sneed , T. A. Weingeist (Eds.) Practical Applications of Laser Surgery in Ophthalmology. Nowalk, CT: Appleton & Lange.

Alward, W. (1991). Laser iridotomy (Chapter 12). In S. R. Sneed , T. A. Weingeist (Eds.) Practical Applications of Laser Surgery in Ophthalmology. Norwalk, CT: Appleton & Lange.

Alward, W. L., Krasnow, M. A., Keech, R. V., Pulido, J. S. & Sutton, G. L. (1991). Persistent hyperplastic primary vitreous with glaucoma presenting in infancy. Archives of Ophthalmology, 109, 1063-1064. PMID: 1867540.

Alward, W. (1991). Review of End Note Plus. American Journal of Ophthalmology, 111(6), 780-781.

Alward, W. L., Krachmer, J. H. & Macsai, M. S. (1990). Arthrogryposis multiplex congenita with Peter's anomaly. Journal of pediatric ophthalmology and strabismus, 27(6), 329. PMID: 2099778.

Haynes, W. L., Johnson, A. T. & Alward, W. L. (1990). Inhibition of exercise-induced pigment dispersion in a patient with the pigmentary dispersion syndrome. American journal of ophthalmology, 109(5), 601-2. PMID: 2139759.

Alward, W. L., Munden, P. M., Verdick, R. E., Perell, H. R. & Thompson, H. S. (1990). Use of infrared videography to detect and record iris transillumination defects. Archives of ophthalmology, 108(5), 748-50. PMID: 2334336.

Alward, W. (1990). Review of Laser Microsurgery of Glaucoma by L Buratto, A Ricci, and D Vitali. American Journal of Ophthalmology, 109(4), 493.

Bennett, S. R., Alward, W. L. & Folberg, R. (1989). An autosomal dominant form of low-tension glaucoma. American journal of ophthalmology, 108(3), 238-44. PMID: 2774031.

Anderson, D. R., Feuer, W. J., Alward, W. L. & Skuta, G. L. (1989). Threshold equivalence between perimeters. American journal of ophthalmology, 107(5), 493-505. PMID: 2712132.

Alward, W. L., Byrne, S. F., Hughes, J. R. & Hodapp, E. A. (1989). Dislocated lens nuclei simulating choroidal melanomas. Archieves of Ophthalmology, 107, 1463-1464.

(1989). Fluorouracil filtering surgery study one-year follow-up. American Journal of Ophthalmology, 108(6), 625-635. PMID: 2688428.

Alward, W. (1989). Review of Manual of Glaucoma Diagnosis and Management by Theodore Krupin. American Journal of Ophthalmology, 107(4), 443.

Alward, W. (1989). Review of Perspectives in Glaucoma by MB Shields, IP Pollack, and AE Kolker. Ophthalmologica, 199, 173.

Alward, W. (1989). Uveitic Glaucoma (Chapter 54D). In T. D. Duane , J. Ed (Eds.) Clinical Ophthalmology. Philadelphia: Harper and Row.

Alward, W. L., Hodapp, E. A., Parel, J. M. & Anderson, D. R. (1988). Argon laser endophotocoagulator closure of cyclodialysis clefts. American journal of ophthalmology, 106(6), 748-9. PMID: 3195659.

Relf, S. J., Gharagozloo, N. Z., Skuta, G. L., Alward, W. L., Anderson, D. R. & Brubaker, R. F. (1988). Thymoxamine reverses phenylephrine-induced mydriasis. American journal of ophthalmology, 106(3), 251-5. PMID: 2971321.

Hall, D. B., McMahon, B. J., Alward, W. & Heyward, W. L. (1986). Re-evaluation of the association between sex, age, and acute infection with hepatitis B virus in Yupik Eskimos. (Vols. 153). pp. 1180-1181. Journal of Infectious Diseases.

Alward, W. L., Hall, D. B. & Heyward, W. L. (1986). The hepatitis B carrier state in the development of primary hepatocellular carcinoma. Journal of Infectious Diseases, 153, 171-172. PMID: 3001192.

Alward, W. L., Bender, T. R., Demske, J. A. & Hall, D. B. (1985). High prevalence of myopia among young adult Yupik Eskimos. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 20(7), 241-5. PMID: 4092169.

Heyward, W. L., Bender, T. R., McMahon, B. J., Hall, D. B., Francis, D. P., Lanier, A. P., Alward, W. L., Ahtone, J. L., Murphy, B. L. & Maynard, J. E. (1985). The control of hepatitis B virus infection with vaccine in Yupik Eskimos. Demonstration of safety, immunogenicity, and efficacy under field conditions. American journal of epidemiology, 121(6), 914-23. PMID: 3160233.

McMahon, B. J., Alward, W. L., Hall, D. B., Heyward, W. L., Bender, T. R., Francis, D. P. & Maynard, J. E. (1985). Acute hepatitis B virus infection: relation of age to the clinical expression of disease and subsequent development of the carrier state. The Journal of infectious diseases, 151(4), 599-603. PMID: 3973412.

Alward, W. L., McMahon, B. J., Hall, D. B., Heyward, W. L., Francis, D. P. & Bender, T. R. (1985). The long-term serological course of asymptomatic hepatitis B virus carriers and the development of primary hepatocellular carcinoma. The Journal of infectious diseases, 151(4), 604-9. PMID: 2982971.

Ireland, B., Knutson, L., Alward, W. & Hall, D. B. (1985). Pertussis: A study of incidence and mortality in a Yukon-Kuskokwim Delta epidemic. In R. Fortuine (Eds.) Circumpolar Health 84. pp. 229-234. Seattle: University of Washington Press.

Alward, W., McMahon, B. J., Hall, D. B., Heyward, W. L., Francis, D. P. & Bender, T. R. (1985). The Long-Term Serological Course of Asymptomatic Hepatitis B Virus Carriers and the Development of Primary Hepatocellular Carcinoma. Journal of Infectious Diseases, 151, 604-609.

Heyward, W. L., Bender, T. R., McMahon, B. J., Hall, D. B., Francis, D. P., Lanier, A. P., Alward, W., Ahton, J. L., Murphy, B. L. & Maynard, J. E. (1985). Use of hepatitis B vaccine in a population hyperendemic for hepatitis B virus infection. American Journal of Epidemiology, 21, 914-923. PMID: 3160233.

Silimperi, D. R., Alward, W. L. (1984). Microbiologic investigation of the Barrow frozen bodies. Artic Anthropology, 21, 117-121.

Alward, W. L. (1982). Suspect botulism - Hooper Bay Alaska (CDC). Morbidity and Mortality Weekly Report.