Next Generation Sequencing Interest Group - ATAC-Seq: a first glimpse into chromatin states

Tuesday, February 18, 2020, 3:00pm to 4:00pm
Eckstein Medical Research Building , Seebohm Conference Room (283)
431 Newton Road, Iowa City, IA 52246
Chromatin accessibility is an essential component of gene regulation of biological processes in specific cells. Assay for Transposase Accessible Chromatin with high-throughput sequencing (ATAC-seq) is an effective way to probe for chromatin accessibility at a genome-wide level and has become a powerful tool to understand dynamic gene expression regulation. In this talk, I will summarize both principle and features of ATAC-seq, and highlight its applications in basic and clinical research