Hearing Protection for All Musicians - Music and Medicine on MondayClick Here

Botox/Xeomin/Botulinum Toxin Injection to Salivary Glands for Drooling, Sialorrhea, Hypersalivation

last modified on: Mon, 08/07/2023 - 16:19

See also: 

  1. Ultrasound Guided FNA Fine Needle Aspiration Biopsy
  2. Botulinum neurotoxin treatment of salivary gland disorders
  3. Botulinum neurotoxin infusion to the parotid via Stensen's duct Research protocol (IRB approved) - and published online: Intraductal Salivary Gland Infusion With Botulinum Toxin - Schwalje - 2019 - Laryngoscope Investigative Otolaryngology - Wiley Online Library
  4. Video of onabotulinumtoxinA (Botox) infusion into left parotid gland with 25 gauge Chiba needle
  5. Hypersalivation Ptyalism Sialorrhea
  6. Botulinum Toxin Treatment for Sialadenitis (OnabotulinumtoxinA - Botox®) (IncobotulinumA - Xeomin®) and (AbobotulinumtoxinA - Dysport®) Salivary Swelling

Case #1: Hyper-salivation addressed with 4 gland Botox insufflation

Case #2: Excessive salivary flow from right parotid following cancer resection accumulating under intraoral flap reconstruction


Walter U and Dressler D: Ultrasound-guided botulinum toxin injections in neurology: technique, indications and future perspectives Expert Rev Neruothe. 2014 Aug;14(8):923-36

Cardona I, Mosseri A, Saint-Martin C, Daniel SJ: The Repetitive Usage of Onabotulinum Toxin type A into Savliary Glands for the management of Sialorrhea in the Pediatric Populatin: an Ultrasound Measurement.  Research Poster accessed on-line 6-28-2015 http://www.researchposters.com/Posters/COSM/COSM2015/H027.pdf

Petracca M, Guidubaldi A, Ricciardi L, Ialongo T, Del Grande A, Mulas D, Di Stasio E, Rita Bentivoglio A: Botulinum Toxin A and B in sialorrhea: Long-term data and literature overview.  Toxicon 107 (2015) 129-140

Schwalje AT, Hoffman HT. Salivary Gland Infusion With Botulinum Toxin.Laryngoscope Investig Otolaryngol. 2019 Sep 3;4(5):520-525. doi: 10.1002/lio2.306. eCollection 2019 Oct.

Ribeiro LB, Xerez DR, Maliska C, de Souza SAL, Costa MMB. Qualitative and quantitative scintigraphy in sialorrhea before and after botulinum toxin injection. Laryngoscope. 2019 Nov;129(11):2521-2526. doi: 10.1002/lary.27826. Epub 2019 Jan 28. PMID: 30693525.

Tiigimäe-Saar J, Taba P, Tamme T. Does Botulinum neurotoxin type A treatment for sialorrhea change oral health? Clin Oral Investig. 2017 Apr;21(3):795-800. doi: 10.1007/s00784-016-1826-z. Epub 2016 Apr 26. PMID: 27114092.