Updated by Piper Wenzel, BS April 2024
return to: Collett-Sicard Syndrome
- Also called neuroschwannoma, neuroma, or neurilemmoma (Loperfido 2023)
- Around 25-45% of extracranial schwannomas occur in the head and neck region (Sandler 2019)
- Benign uncommon tumor of the CN X Schawnn cells (Loperfido 2023)
- Most cases present between the 3rd to 5th decades; female = male (Loperfido 2023)
- Usually asymptomatic but may cause hoarsness due to vocal cord paralysis (Loperfido 2023)
- Larger tumors may present with dysphagia, dysphonia, and dyspnea due to airway obstruction (Loperfido 2023)
- Displaces internal jugular vein posterolaterally; displaces common and internal carotid arteries anteriorly (Sandler 2019)
- Ultrasound: "round or elliptical cross-section with a clear edge and an internal echo reflective of histology"; may have cystic changes (Loperfido 2023)
- On CT: Muscle density mass on non-contrast, uniformly enhancing and well-circumscribed mass with contrast
- On MR: variable signal with no flow voids on T1, hyperintense with possible cystic structures on T2, dense and uniform enhancement of T1 post-contrast
References
Loperfido A, Celebrini A, Fionda B, Bellocchi G, Cristalli G. Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review. Medicina (Kaunas). 2023 May 24;59(6):1013. doi: 10.3390/medicina59061013. PMID: 37374217; PMCID: PMC10303656.
Sandler ML, Sims JR, Sinclair C, Sharif KF, Ho R, Yue LE, Téllez MJ, Ulkatan S, Khorsandi AS, Brandwein-Weber M, Urken ML. Vagal schwannomas of the head and neck: A comprehensive review and a novel approach to preserving vocal cord innervation and function. Head Neck. 2019 Jul;41(7):2450-2466. doi: 10.1002/hed.25758. Epub 2019 Apr 7. PMID: 30957342.