Edwin (Ted) Abel, PhD
Professor and Chair/Department Executive Officier
Neuroscience and Pharmacology
Office: 2314 PBDB
Office Phone: 319-353-4534
Lab: 2400 PBDB
319-353-4534
Lab Website: https://tedabel.lab.uiowa.edu/
Sleep and Memory, Autism
The primary focus of research in the Abel lab is to understand the cellular and molecular mechanisms of long-term memory storage with a focus on the mammalian hippocampus. One of the hallmarks of long-term memory storage is that it requires the synthesis of new genes and new proteins, which act to alter the strength of synaptic connections within appropriate neuronal circuits in the brain. How are the various signals acting on a neuron integrated to give rise to appropriate changes in gene expression? How are changes in gene expression maintained to sustain memories for days, months and even years? What role does sleep play in memory storage? How is hippocampal function altered in mouse models of psychiatric and neurodevelopmental disorders?
PubMed link
Department/Program Affiliations:
Molecular MedicineNeuroscience and Pharmacology