Janice Staber, MD
Associate Professor
Pediatrics
Office: 3080J ML
Office Phone: 319-335-6688
Lab: 3080 ML
Lab Website: https://medicine.uiowa.edu/pediatrics/profile/janice-staber
Neuro-outcomes in hemophilia A
My research explores the effects of cerebral microbleeds and neuroinflammation on brain structure and behavior changes in hemophilia A. We utilize piggyBac-mediated non-viral gene therapy to determine if we can correct these changes. My research focuses on three key knowledge gaps in hemophilia: 1) mechanisms leading to decreased brain volumes in hemophilia A, 2) defining the executive dysfunction and behavior changes in hemophilia A, and 3) neuroinflammatory biomarkers and cell signaling to predict changes in the brain.
PubMed link
Department/Program Affiliations:
Iowa Neuroscience InstitutePediatrics