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Recent REU Research Projects

Characterizing PilZ Domain Protein Interactions with Type IV Pili Effectors in Biased Twitching Motility in Pseudomonas aeruginosa

TRAF3 Regulation of Type I Interferon Signaling in B Cells

Unveiling the differential Impact of MHV-JHM & MHV-A59 on Virulence and Innate Immune Antagonism

Clostridioides difficile: identification of conserved and novel cell division proteins in an important pathogen

Determining the Essential Nature of Hfq in Acinetobacter baumannii

Identification of Putative Divisome Proteins in Clostridioides difficile

The effects of angiogenin overexpression on transfer RNA fragments and the reactivation of Kaposi's Sarcoma-Associated Herpesvirus

Investigating the Role of Lmo2839: A Potential Virulence Factor in Listeria monocytogenes during Animal Infection

Cross-feeding in the gut microbiome: how bacterial contact regulates polysaccharide usage

In vitro characterization of the Chlamydia trachomatis effector protein TmeA and its interactions with host proteins N-WASP and Toca-1

Identifying the Endonuclease Responsible for the Cleavage of Pre-tRNA During Gammaherpesvirus Infection

Examination of Listeria monocytogenes protein P60 for deubiquitination activity

Atypical B-cells and their mysterious roles in Plasmodium infections

Role of CIC in the Regulation of the Antiviral Gene Promoter TRIM22

Utilizing Reverse Genetics to Understand the Functions of Mouse Hepatitis Virus I gene

Interactions between ICP22 and heterodimer proteins UL31 and UL34

Identification of Genes Controlled by CDR1313 and their Role in Lysozyme Resistance in C. difficile

Investigation of Daughter Cell Separation in E. coli

Hypoxia Prevents the Induction of the Immunoproteasome Subunits in Murine Melanoma

Using Whole Genome Sequencing to Identify Mutations in E. coli Leading to Cefsulodin Resistance

The Effects of Glycerol Monolaurate Based Pharmaceuticals on the Function of T Cells

CRISPRi screening of essential genes in the anaerobe C. difficile and characterization of operon important for cell division

The inhibitory domain of IRF7 is required for SAMHD1 interaction

Engineering E. coli Nissle 1917 to be a Methylotroph that Degrades Trimethylamine

Screening of essential genes in C. difficile with CRISPRi identifies operon important in cell wall biogenesis

Conservation of HSV-1 pUL51 Homologs Interaction with Dynactin

Isolation and Characterization of Lysozyme Resistant Mutants in Clostridioides difficile

Targeting Potential Type III Secretion System Regulators Using CRISPRi

Determining the mechanisms of antimicrobial peptide LL-37 protection in a model of necrotizing enterocolitis (NEC)

Role of TET proteins in CD8 T-Cell Differentiation during Plasmodium infection

Impact of H. pylori infected PMNs on T cell Proliferation

Using Cell Culture Evolution to Explore Functional Interactions in Herpes Virus Nuclear Egress

Second messenger signaling and surface colonization strategies in bacteria: defining a c-di-GMP driven regulatory network in Vibrio parahaemolyticus

Determining the Function of Chlamydia trachomatis Effectors Using a Yeast Suppressor Screen

Innate immune response of skin cells to Ebola virus entry

Fishing for new regulators of the enterotoxin gene cluster in Staphylococcus aureus

Transcriptional and post-transcriptional regulation of the Pseudomonas aeruginosa type III secretion system

Effects of glycerol monolaurate on human B cells

Investigating how cyclic dimeric GMP is involved in lifestyle choices of Vibrio parahaemolyticus

Bacterial cell division: localizing enzymes required for peptidoglycan synthesis in the presence of β-lactam antibiotics

The immune response to Maleria: temporal role of host signaling protein IL-10 during Plasmodium infection

Role of Chlamydia trachomatis type III secreted proteins in serovar-specific disease

Phenotypes of individual point mutations that affect function of HSV-1 nuclear egress complex

Alteration of peptidoglycan disrupts surface sensing signal transduction in Vibrio parahaemolyticus

Novel antivirulence molecules that inhibit type III secretion system activity in Pseudomonas aeruginosa

TCR-mediated signaling proteins and their association with nuclear GRB2

Bacterial cell division: how do cell wall binding proteins find the midcell?

The Bacillus subtilis response to lysozyme: mutation analysis of RsiV, the anti-sigma factor that senses lysozyme

Prophages as molecular regulatory switches in Staphylococcus aureus

Biochemical counter-regulation of B cell function by IL-10 and IFN-γ

Peptidoglycan transmits the surface sensing signal to induce swarming in bacteria

Warfare of the skin microbiome: impact of commensal Staphylococcal species on S. aureus biofilm formation

In vitro characterization and validation of two component systems in Neisseria gonorrhoeae FA 1090

Unique features of the RsiV signal peptide and their impact on σVactivation and lysozyme resistance in B. subtilis

Effects of empty expression vectors on Pseudomonas aeruginosa type III secretion

Virus strain dependent inflammasome activation in macrophages infected with RSV

Analyzing the effects of UL7 & glycoprotein E deletion on cell-to-cell-spread in HSV-1