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Fillan Grady, M5G

fillan-grady@uiowa.edu

 

MSTP Learning Community:  Boulware

MSTP Entry Date:  July 23, 2016

PhD Program:

Neuroscience

Mentors:

Gordon Buchanan, MD, PhD

Joel Geerling, MD, PhD

Graduate Profile Lab Website Buchanan

Identifying the neuro-anatomical basis of arousal

Fillan studies the brainstem circuits responsible for autonomic and homeostatic functions. He is particularly interested in the parabrachial nucleus of the pons, and its role in wakefulness, appetite, and temperature regulation. To accomplish this, he uses cell-type-specific manipulations in rodents, and then measures their EEG changes, food intake, and core temperature


Committees:

  • 2016-2017 - MSTP Recruitment Committee
  • 2016-2017 - MSTP Applicant Task Force
  • 2020-2021 - Retreat & I 'Heart' Science (Chair)

Awards:

  • 2017 - The Lauretta Bender Research Award in Psychiatry, Medical Student Research Day, Sept 15
  • 2020 - Post-Comprehensive Research Fellowship
  • 2021 - Pappajohn Biomedical Institute Best Paper by a Graduate Student

Teaching:

  • 2018 Spring - MOHD III tutor
  • 2018 Fall - M1 Foundations Tutor
  • 2019 Spring - MOHD III tutor
  • 2019 Spring - ACB:6252 Functional Neuroanatomy Teaching Assistant

Education:

2015 - BA, Physics, Mathematics, Biology, Integrated Science - Northwestern University

Publications:

ORCiD: 0000-0003-2008-2405

Cox AJ, Grady F, Velez G, Mahajan VB, Ferguson PJ, Kitchen A, Darbro BW, Bassuk AG. In trans variant calling reveals enrichment for compound heterozygous variants in genes involved in neuronal development and growth. Genet Res (Camb). 2019 Jun 13;101:e8. doi: 10.1017/S0016672319000065. PubMed PMID: 31190668; PubMed Central PMCID: PMC7045018.

Grady F, Peltekian L, Iverson G, Geerling JC. Direct Parabrachial-Cortical Connectivity. Cereb Cortex. 2020 Jul 30;30(9):4811-4833. doi: 10.1093/cercor/bhaa072. PubMed PMID: 32383444; PubMed Central PMCID: PMC7391272.

Huang D, Grady FS, Peltekian L, Laing JJ, Geerling JC. Efferent projections of CGRP/Calca-expressing parabrachial neurons in mice. J Comp Neurol. 2021 Aug 1;529(11):2911-2957. doi: 10.1002/cne.25136. Epub 2021 Mar 25. PubMed PMID: 33715169; PubMed Central PMCID: PMC8165036.

Huang D, Grady FS, Peltekian L, Geerling JC. Efferent projections of Vglut2, Foxp2, and Pdyn parabrachial neurons in mice. J Comp Neurol. 2021 Mar;529(4):657-693. doi: 10.1002/cne.24975. Epub 2020 Sep 21. PubMed PMID: 32621762; PubMed Central PMCID: PMC7775907.

Karthik S, Huang D, Delgado Y, Laing JJ, Peltekian L, Iverson GN, Grady F, Miller RL, McCann CM, Fritzsch B, Iskusnykh IY, Chizhikov VV, Geerling JC. Molecular ontology of the parabrachial nucleus. J Comp Neurol. 2022 Feb 8. doi: 10.1002/cne.25307. Epub ahead of print. PMID: 35134251.

Grady FS, Graff SA, Aldridge GM, Geerling JC. BoutonNet: an automatic method to detect anterogradely labeled presynaptic boutons in brain tissue sections. Brain Struct Funct. 2022 Jun 1;. doi: 10.1007/s00429-022-02504-y. [Epub ahead of print] PubMed PMID: 35648216.