Recent Publications

Bierlein-De La Rosa, Gabby

Khan KM, Bierlein-De La Rosa G, Biggerstaff N, Pushpavathi Selvakumar G, Wang R, Mason S, Dailey ME, Marcinkiewcz CA. Adolescent ethanol drinking promotes hyperalgesia, neuroinflammation and serotonergic deficits in mice that persist into adulthood. Brain Behav Immun. 2022 Jul 27:S0889-1591(22)00334-8. doi: 10.1016/j.bbi.2022.07.160. Epub ahead of print. PMID: 35907582.

Bowen, Jayden L.

Murthy S, Baruah S, Bowen JL, Keck K, Wagner BA, Buettner GR, Sykes DB, Klesney-Tait J. TREM-1 is required for enhanced OpZ-induced superoxide generation following priming. J Leukoc Biol. 2022 Jan 24. doi: 10.1002/JLB.3A0421-212R. Epub ahead of print. PMID: 35075692.

Buchanan, Jane L.

Sun M, Hines N, Scerbo D, Buchanan J, Wu C, Ten Eyck P, Zepeda-Orozco D, Taylor EB, Jalal DI. Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD. Antioxidants (Basel). 2022 Jun 29;11(7):1297. doi: 10.3390/antiox11071297. PMID: 35883787; PMCID: PMC9312025.

Brashears CB, Prudner BC, Rathore R, Caldwell KE, Dehner CA, Buchanan JL, Lange SES, Poulin N, Sehn JK, Roszik J, Spitzer D, Jones KB, O'Keefe R, Nielsen TO, Taylor EB, Held JM, Hawkins W, Van Tine BA. Malic Enzyme 1 Absence in Synovial Sarcoma Shifts Antioxidant System Dependence and Increases Sensitivity to Ferroptosis Induction with ACXT-3102. Clin Cancer Res. 2022 Aug 15;28(16):3573-3589. doi: 10.1158/1078-0432.CCR-22-0470. PMID: 35421237; PMCID: PMC9378556.

Dong Q, Xiu Y, Wang Y, Hodgson C, Borcherding N, Jordan C, Buchanan J, Taylor E, Wagner B, Leidinger M, Holman C, Thiele D, O'Brien S, Xue H, Zhao J, Li Q, Meyerson H, Boyce B, Zhao C. HSF1 is a Driver of Leukemia Stem Cell Self-Renewal in Acute Myeloid Leukemia. Nature Communications. (Accepted 10-5-2022)

Dajles, Andres

Dajles A, Cavanaugh J. Probabilistic Pairwise Model Comparisons Based on Bootstrap Estimators of the Kullback–Leibler Discrepancy. Entropy. 2022; 24(10):1483. doi: 10.3390/e24101483

Hurley-Novatny, Amelia C.

Hurley-Novatny AC, Allbritton-King JD, Jha S, Cowen EW, Colbert RA, Navid F, Bhattacharyya T. Fibroblasts from Patients with Melorheostosis Promote Angiogenesis in Healthy Endothelial Cells through Secreted Factors. J Invest Dermatol. 2022 Sep;142(9):2406-2414.e5. doi: 10.1016/j.jid.2022.02.006. Epub 2022 Feb 19. PubMed PMID: 35189151; PubMed Central PMCID: PMC9388700.

Jain, Akansha

Guardia CM, Jain A, Mattera R, Friefeld A, Li Y, Bonifacino JS. RUSC2 and WDR47 oppositely regulate kinesin-1-dependent distribution of ATG9A to the cell periphery. Mol Biol Cell. 2021 Aug 25:mbcE21060295. doi: 10.1091/mbc.E21-06-0295. Epub ahead of print. PMID: 34432492. (Pre-MSTP Publication)

Yu W, Moninger TO, Thurman AL, Xie Y, Jain A, Zarei K, Powers LS, Pezzulo AA, Stoltz DA, Welsh MJ. Cellular and molecular architecture of submucosal glands in wild-type and cystic fibrosis pigs. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4). doi: 10.1073/pnas.2119759119. PubMed PMID: 35046051; PubMed Central PMCID: PMC8794846.

Rehman T, Karp PH, Thurman AL, Mather SE, Jain A, Cooney AL, Sinn PL, Pezzulo AA, Duffey ME, Welsh MJ. WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia. Am J Respir Cell Mol Biol. 2022 Jul 18. doi: 10.1165/rcmb.2022-0172OC. Epub ahead of print. PMID: 35849656.

Jain, A, Kim, B., Yu, W., Moninger, T., Karp, P., Wagner, B., Welsh, M. (2024) Mitochondrial uncoupling proteins protect human airway epithelial ciliated cells from oxidative damage. PNAS. PMID: 38416686.

Johnson,D., Colijn, S., Richee, J., Yano, J., Burns, M., Davis, A. E., Pham, V. N., Saric, A., Jain, A., Yin, Y., Castranova, D., Melani, M., Fujita, M., Grainger, S., Bonifacino, J., Weinstein, B. M., and Stratman, A. N. (2024). Regulation of angiogenesis by endocytic trafficking mediated by cytoplasmic dynein 1 light intermediate chain 1. BioRxiv. doi: https://doi.org/10.1101/2024.04.01.587559.

Abou Alaiwa, M.H. Hilkin, B.M., Price, M.P., Gansemer, N.D., Rector, M.R., Stroik, M.R., Powers, L.S., Whitworth, K.M., Samuel, M.S., Jain, A., Ostedgaard, L.S., Ernst, S.E., Philibet, W., Boyken, L.D., Moninger, T.O., Karp, P.H., Hornick, D.B., Sinn, P.L., Fischer, A.J., Pezzulo, A.A., McCray, P.B., Meyerholz, D.K., Zabner, J., Prather, R.S., Welsh., M.J., Stoltz, D.A.  (2024) Development and initial characterization of pigs with DNAI1 mutations and primary ciliary dyskinesia [Preprint]. doi:10.1101/2024.05.22.594822.

Lozano, Lola A.

Voigt AP, Mullin NK, Mulfaul K, Lozano LP, Wiley LA, Flamme-Wiese MJ, Boese EA, Han IC, Scheetz TE, Stone EM, Tucker BA, Mullins RF. Choroidal Endothelial and Macrophage Gene Expression in Atrophic and Neovascular Macular Degeneration. Hum Mol Genet. 2022 Feb 19:ddac043. doi: 10.1093/hmg/ddac043. Epub ahead of print. PMID: 35181781.

Lozano LP, Tucker BA, Hinz CJ, Boldt HC, Binkley EM. Retinal Capillary Hemangioma Leading to a Diagnosis of von Hippel-Lindau Disease in a Patient with Retinopathy of Prematurity. Case Rep Ophthalmol. 2022 May-Aug;13(2):323-329. doi: 10.1159/000524297. eCollection 2022 May-Aug. PubMed PMID: 35702652; PubMed Central PMCID: PMC9149552.

Miller, Matthew J.

Basisty N, Shulman N, Wehrfritz C, Marsh AN, Shah S, Rose J, Ebert S, Miller M, Dai DF, Rabinovitch PS, Adams CM, MacCoss MJ, MacLean B, Schilling B. TurnoveR: A Skyline External Tool for Analysis of Protein Turnover in Metabolic Labeling Studies. J Proteome Res. 2022 Sep 27. doi: 10.1021/acs.jproteome.2c00173. PMID: 36165806.

Ebert SM, Rasmussen BB, Judge AR, Judge SM, Larsson L, Wek RC, Anthony TG, Marcotte GR, Miller MJ, Yorek MA, Vella A, Volpi E, Stern JI, Strub MD, Ryan Z, Talley JJ, Adams CM. Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy. J Nutr. 2022 Apr 1;152(4):926-938. doi: 10.1093/jn/nxab440. PMID: 34958390; PMCID: PMC8970988.

Mix, Maddie R.

Mix MR, Harty JT. Keeping T cell memories in mind. Trends Immunol. 2022 Dec;43(12):1018-1031. doi: 10.1016/j.it.2022.10.001. Epub 2022 Nov 8. Review. PubMed PMID: 36369103; PubMed Central PMCID: PMC9691610.

Fuller MJ, Mix MR, Voigt E, Hoffmann DS, Geyer PK. Guidelines for organizing accessible and inclusive research retreats. Trends Biochem Sci. 2024 Jan 6:S0968-0004(23)00298-0. doi: 10.1016/j.tibs.2023.12.003. Epub ahead of print. PMID: 38184399.

Todd BP, Luo Z, Gilkes N, Chimenti MS, Peterson Z, Mix MR, Harty JT, Nickl-Jockschat T, Ferguson PJ, Bassuk AG, Newell EA. Selective neuroimmune modulation by type I interferon drives neuropathology and neurologic dysfunction following traumatic brain injury. Acta Neuropthol Commun. 2023 Aug 18;11(1):134. doi: 10.1186/s40478-023-01635-5. PMID: 37596685.

Hassert M, Pewe LL, He R, Heidarian M, Phruttiwanichakun P, van de Wall S, Mix MR, Salem AK, Badovinac VP, Harty JT. Regenerating murine CD8+ lung tissue resident memory T cells after targeted radiation exposure. J Exp Med. 2024 Mar 4;221(3):e20231144. doi: 10.1084/jem.20231144. Epub 2024 Feb 16. PMID: 38363548.

Mullin, Nathaniel K.

Mulfaul K, Mullin NK, Giacalone JC, Voigt AP, DeVore M, Stone EM, Tucker BA, Mullins RF. Local Factor H production by human choroidal endothelial cells mitigates complement deposition: implications for macular degeneration. J Pathol. 2022 Jan 17. doi: 10.1002/path.5867. Epub ahead of print. PMID: 35038170.

Voigt AP, Mullin NK, Mulfaul K, Lozano LP, Wiley LA, Flamme-Wiese MJ, Boese EA, Han IC, Scheetz TE, Stone EM, Tucker BA, Mullins RF. Choroidal Endothelial and Macrophage Gene Expression in Atrophic and Neovascular Macular Degeneration. Hum Mol Genet. 2022 Feb 19:ddac043. doi: 10.1093/hmg/ddac043. Epub ahead of print. PMID: 35181781.

Pape, Daniel J.

Rauckhorst AJ, Borcherding N, Pape DJ, Kraus AS, Scerbo DA, Taylor EB. Mouse tissue harvest-induced hypoxia rapidly alters the in vivo metabolome, between-genotype metabolite level differences, and 13C-tracing enrichments. Mol Metab. 2022 Sep 11:101596. doi: 10.1016/j.molmet.2022.101596. Epub ahead of print. PMID: 36100179.

Romano Ibarra, Guillermo S.

Thurman AL, Li X, Villacreses R, Yu W, Gong H, Mather SE, Romano-Ibarra GS, Meyerholz DK, Stoltz DA, Welsh MJ, Thornell IM, Zabner J, Pezzulo AA. A Single-Cell Atlas of Large and Small Airways at Birth in a Porcine Model of Cystic Fibrosis. Am J Respir Cell Mol Biol. 2022 Mar 2. doi: 10.1165/rcmb.2021-0499OC. Epub ahead of print. PMID: 35235762.

Van Ert, Hannah

Van Ert HA, Bohan DW, Rogers K, Fili M, Rojas Chávez RA, Qing E, Han C, Dempewolf S, Hu G, Schwery N, Sevcik K, Ruggio N, Boyt D, Pentella MA, Gallagher T, Jackson JB, Merrill AE, Knudson CM, Brown GD, Maury W, Haim H. Limited Variation between SARS-CoV-2-Infected Individuals in Domain Specificity and Relative Potency of the Antibody Response against the Spike Glycoprotein. Microbiol Spectr. 2022 Jan 26:e0267621. doi: 10.1128/spectrum.02676-21. Epub ahead of print. PMID: 35080430.

Voigt, Ellen M.

Kohlmeyer JL, Kaemmer CA, Lingo JJ, Voigt E, Leidinger MR, McGivney GR, Scherer A, Koppenhafer SL, Gordon DJ, Breheny P, Meyerholz DK, Tanas MR, Dodd RD, Quelle DE. Oncogenic RABL6A promotes NF1-associated MPNST progression in vivo. Neurooncol Adv. 2022 Apr 9;4(1):vdac047. doi: 10.1093/noajnl/vdac047. PMID: 35571990; PMCID: PMC9092646.

Koppenhafer SL, Goss KL, Voigt E, Croushore E, Terry WW, Ostergaard J, Gordon PM, Gordon DJ. Inhibitor of DNA binding 2 (ID2) regulates the expression of developmental genes and tumorigenesis in ewing sarcoma. Oncogene. 2022 May;41(20):2873-2884. doi: 10.1038/s41388-022-02310-0. Epub 2022 Apr 14. PMID: 35422476; PMCID: PMC9107507.

Wahlen, Madison M.

Wahlen MM, Schroeder MC, Johnson EC, Lizarraga IM, Engelbart JM, Tatman DJ, Wagi C, Charlton ME, Birken SA. Identifying Core Functions of an Evidence-Based Intervention to Improve Cancer Care Quality in Rural Hospitals. Front Health Serv. 2022;2:891574. doi: 10.3389/frhs.2022.891574. Epub 2022 Apr 28. PMID: 36188431; PMCID: PMC9524475.