Recent Publications

Bierlein-De La Rosa, Gabby

Khan KM, Bierlein-De La Rosa G, Biggerstaff N, Pushpavathi Selvakumar G, Wang R, Mason S, Dailey ME, Marcinkiewcz CA. Adolescent ethanol drinking promotes hyperalgesia, neuroinflammation and serotonergic deficits in mice that persist into adulthood. Brain Behav Immun. 2022 Jul 27:S0889-1591(22)00334-8. doi: 10.1016/j.bbi.2022.07.160. Epub ahead of print. PMID: 35907582.

Bowen, Jayden L.

Murthy S, Baruah S, Bowen JL, Keck K, Wagner BA, Buettner GR, Sykes DB, Klesney-Tait J. TREM-1 is required for enhanced OpZ-induced superoxide generation following priming. J Leukoc Biol. 2022 Jan 24. doi: 10.1002/JLB.3A0421-212R. Epub ahead of print. PMID: 35075692.

Buchanan, Jane L.

Sun M, Hines N, Scerbo D, Buchanan J, Wu C, Ten Eyck P, Zepeda-Orozco D, Taylor EB, Jalal DI. Allopurinol Lowers Serum Urate but Does Not Reduce Oxidative Stress in CKD. Antioxidants (Basel). 2022 Jun 29;11(7):1297. doi: 10.3390/antiox11071297. PMID: 35883787; PMCID: PMC9312025.

Brashears CB, Prudner BC, Rathore R, Caldwell KE, Dehner CA, Buchanan JL, Lange SES, Poulin N, Sehn JK, Roszik J, Spitzer D, Jones KB, O'Keefe R, Nielsen TO, Taylor EB, Held JM, Hawkins W, Van Tine BA. Malic Enzyme 1 Absence in Synovial Sarcoma Shifts Antioxidant System Dependence and Increases Sensitivity to Ferroptosis Induction with ACXT-3102. Clin Cancer Res. 2022 Aug 15;28(16):3573-3589. doi: 10.1158/1078-0432.CCR-22-0470. PMID: 35421237; PMCID: PMC9378556.

Dong Q, Xiu Y, Wang Y, Hodgson C, Borcherding N, Jordan C, Buchanan J, Taylor E, Wagner B, Leidinger M, Holman C, Thiele D, O'Brien S, Xue H, Zhao J, Li Q, Meyerson H, Boyce B, Zhao C. HSF1 is a Driver of Leukemia Stem Cell Self-Renewal in Acute Myeloid Leukemia. Nature Communications. (Accepted 10-5-2022)

Burghardt, Elliot L.

Schmitz AH, Wood KE, Burghardt EL, Koestner BP, Wendt LH, Badheka AV, Sharathkumar AA. Thromboprophylaxis for children hospitalized with COVID-19 and MIS-C. Res Pract Thromb Haemost. 2022 Aug 7;6(5):e12780. doi: 10.1002/rth2.12780. PMID: 35949885; PMCID: PMC9357887.

Dajles, Andres

Dajles A, Cavanaugh J. Probabilistic Pairwise Model Comparisons Based on Bootstrap Estimators of the Kullback–Leibler Discrepancy. Entropy. 2022; 24(10):1483. doi: 10.3390/e24101483

Grady, Fillan S.

Karthik S, Huang D, Delgado Y, Laing JJ, Peltekian L, Iverson GN, Grady F, Miller RL, McCann CM, Fritzsch B, Iskusnykh IY, Chizhikov VV, Geerling JC. Molecular ontology of the parabrachial nucleus. J Comp Neurol. 2022 Feb 8. doi: 10.1002/cne.25307. Epub ahead of print. PMID: 35134251.

Grady FS, Graff SA, Aldridge GM, Geerling JC. BoutonNet: an automatic method to detect anterogradely labeled presynaptic boutons in brain tissue sections. Brain Struct Funct. 2022 Jul;227(6):1921-1932. doi: 10.1007/s00429-022-02504-y. Epub 2022 Jun 1. PMID: 35648216.

Grady FS, Boes AD, Geerling JC. A Century Searching for the Neurons Necessary for Wakefulness. Front Neurosci. 2022 Jul 19;16:930514. doi: 10.3389/fnins.2022.930514. PMID: 35928009; PMCID: PMC9344068.

Greiner, Alex

Greiner A, Mehdi H, Cevan C, Gutman R, London B.  Additional Evidence Implicating GPDIL in the Pathogenesis of Brugada Syndrome in a Large Multi-generational Family.  medRxiv 2022.09.17.22280058; https://doi.org/10.1101/2022.09.17.22280058.

Gutierrez, Wade R.

Brockman QR, Scherer A, McGivney GR, Gutierrez WR, Voigt AP, Isaacson AL, Laverty EA, Roughton G, Knepper-Adrian V, Darbro B, Tanas MR, Stipp CS, Dodd RD. PRC2 loss drives MPNST metastasis and matrix remodeling. JCI Insight. 2022 Sep 6;. doi: 10.1172/jci.insight.157502. [Epub ahead of print] PubMed PMID: 36066973.

Gutierrez WR, Scherer A, Rytlewski JD, Laverty EA, Sheehan AP, McGivney GR, Brockman QR, Knepper-Adrian V, Roughton GA, Quelle DE, Gordon DJ, Monga V, Dodd RD. Augmenting chemotherapy with low-dose decitabine through an immune- independent mechanism. JCI Insight. 2022 Oct 13:e159419. doi: 10.1172/jci.insight.159419. Epub ahead of print. PMID: 36227698.

Hurley-Novatny, Amelia C.

Hurley-Novatny AC, Allbritton-King JD, Jha S, Cowen EW, Colbert RA, Navid F, Bhattacharyya T. Fibroblasts from Patients with Melorheostosis Promote Angiogenesis in Healthy Endothelial Cells through Secreted Factors. J Invest Dermatol. 2022 Sep;142(9):2406-2414.e5. doi: 10.1016/j.jid.2022.02.006. Epub 2022 Feb 19. PubMed PMID: 35189151; PubMed Central PMCID: PMC9388700.

Jain, Akansha

Yu W, Moninger TO, Thurman AL, Xie Y, Jain A, Zarei K, Powers LS, Pezzulo AA, Stoltz DA, Welsh MJ. Cellular and molecular architecture of submucosal glands in wild-type and cystic fibrosis pigs. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4). doi: 10.1073/pnas.2119759119. PubMed PMID: 35046051; PubMed Central PMCID: PMC8794846.

Rehman T, Karp PH, Thurman AL, Mather SE, Jain A, Cooney AL, Sinn PL, Pezzulo AA, Duffey ME, Welsh MJ. WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia. Am J Respir Cell Mol Biol. 2022 Jul 18. doi: 10.1165/rcmb.2022-0172OC. Epub ahead of print. PMID: 35849656.

Lozano, Lola A.

Voigt AP, Mullin NK, Mulfaul K, Lozano LP, Wiley LA, Flamme-Wiese MJ, Boese EA, Han IC, Scheetz TE, Stone EM, Tucker BA, Mullins RF. Choroidal Endothelial and Macrophage Gene Expression in Atrophic and Neovascular Macular Degeneration. Hum Mol Genet. 2022 Feb 19:ddac043. doi: 10.1093/hmg/ddac043. Epub ahead of print. PMID: 35181781.

Lozano LP, Tucker BA, Hinz CJ, Boldt HC, Binkley EM. Retinal Capillary Hemangioma Leading to a Diagnosis of von Hippel-Lindau Disease in a Patient with Retinopathy of Prematurity. Case Rep Ophthalmol. 2022 May-Aug;13(2):323-329. doi: 10.1159/000524297. eCollection 2022 May-Aug. PubMed PMID: 35702652; PubMed Central PMCID: PMC9149552.

Miller, Matthew J.

Basisty N, Shulman N, Wehrfritz C, Marsh AN, Shah S, Rose J, Ebert S, Miller M, Dai DF, Rabinovitch PS, Adams CM, MacCoss MJ, MacLean B, Schilling B. TurnoveR: A Skyline External Tool for Analysis of Protein Turnover in Metabolic Labeling Studies. J Proteome Res. 2022 Sep 27. doi: 10.1021/acs.jproteome.2c00173. PMID: 36165806.

Ebert SM, Rasmussen BB, Judge AR, Judge SM, Larsson L, Wek RC, Anthony TG, Marcotte GR, Miller MJ, Yorek MA, Vella A, Volpi E, Stern JI, Strub MD, Ryan Z, Talley JJ, Adams CM. Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy. J Nutr. 2022 Apr 1;152(4):926-938. doi: 10.1093/jn/nxab440. PMID: 34958390; PMCID: PMC8970988.

Mix, Maddie R.

Mix MR, Harty JT. Keeping T cell memories in mind. Trends Immunol. 2022 Dec;43(12):1018-1031. doi: 10.1016/j.it.2022.10.001. Epub 2022 Nov 8. Review. PubMed PMID: 36369103; PubMed Central PMCID: PMC9691610.

Fuller MJ, Mix MR, Voigt E, Hoffmann DS, Geyer PK. Guidelines for organizing accessible and inclusive research retreats. Trends Biochem Sci. 2024 Jan 6:S0968-0004(23)00298-0. doi: 10.1016/j.tibs.2023.12.003. Epub ahead of print. PMID: 38184399.

Todd BP, Luo Z, Gilkes N, Chimenti MS, Peterson Z, Mix MR, Harty JT, Nickl-Jockschat T, Ferguson PJ, Bassuk AG, Newell EA. Selective neuroimmune modulation by type I interferon drives neuropathology and neurologic dysfunction following traumatic brain injury. Acta Neuropthol Commun. 2023 Aug 18;11(1):134. doi: 10.1186/s40478-023-01635-5. PMID: 37596685.

Hassert M, Pewe LL, He R, Heidarian M, Phruttiwanichakun P, van de Wall S, Mix MR, Salem AK, Badovinac VP, Harty JT. Regenerating murine CD8+ lung tissue resident memory T cells after targeted radiation exposure. J Exp Med. 2024 Mar 4;221(3):e20231144. doi: 10.1084/jem.20231144. Epub 2024 Feb 16. PMID: 38363548.

Mullin, Nathaniel K.

Mulfaul K, Mullin NK, Giacalone JC, Voigt AP, DeVore M, Stone EM, Tucker BA, Mullins RF. Local Factor H production by human choroidal endothelial cells mitigates complement deposition: implications for macular degeneration. J Pathol. 2022 Jan 17. doi: 10.1002/path.5867. Epub ahead of print. PMID: 35038170.

Voigt AP, Mullin NK, Mulfaul K, Lozano LP, Wiley LA, Flamme-Wiese MJ, Boese EA, Han IC, Scheetz TE, Stone EM, Tucker BA, Mullins RF. Choroidal Endothelial and Macrophage Gene Expression in Atrophic and Neovascular Macular Degeneration. Hum Mol Genet. 2022 Feb 19:ddac043. doi: 10.1093/hmg/ddac043. Epub ahead of print. PMID: 35181781.

Pape, Daniel J.

Rauckhorst AJ, Borcherding N, Pape DJ, Kraus AS, Scerbo DA, Taylor EB. Mouse tissue harvest-induced hypoxia rapidly alters the in vivo metabolome, between-genotype metabolite level differences, and 13C-tracing enrichments. Mol Metab. 2022 Sep 11:101596. doi: 10.1016/j.molmet.2022.101596. Epub ahead of print. PMID: 36100179.

Romano Ibarra, Guillermo S.

Thurman AL, Li X, Villacreses R, Yu W, Gong H, Mather SE, Romano-Ibarra GS, Meyerholz DK, Stoltz DA, Welsh MJ, Thornell IM, Zabner J, Pezzulo AA. A Single-Cell Atlas of Large and Small Airways at Birth in a Porcine Model of Cystic Fibrosis. Am J Respir Cell Mol Biol. 2022 Mar 2. doi: 10.1165/rcmb.2021-0499OC. Epub ahead of print. PMID: 35235762.

Sabree, Shakoora

Hornick EL, Stunz LL, Sabree S, Wu X, Witzig TE, Bishop GA. The Tumor Suppressor Protein TRAF3 Modulates GSK3 Activity and Susceptibility of B Lymphoma Cells to GSK3 Inhibition. Cancers (Basel). 2022 Oct 14;14(20):5029. doi: 10.3390/cancers14205029. PMID: 36291813; PMCID: PMC9599470.

Swanson, Morgan B.

Georgakakos PK, Swanson MB, Ahmed A, Mohr NM. Rural Stroke Patients Have Higher Mortality: An Improvement Opportunity for Rural Emergency Medical Services Systems. J Rural Health. 2022 Jan;38(1):217-227. doi: 10.1111/jrh.12502. Epub 2020 Aug 5. PubMed PMID: 32757239; PubMed Central PMCID: PMC7862426.

Bolte TB, Swanson MB, Kaldjian AM, Mohr NM, McDanel J, Ahmed A. Hospitals That Report Severe Sepsis and Septic Shock Bundle Compliance Have More Structured Sepsis Performance Improvement. J Patient Saf. 2022 Dec 1;18(8):e1231-e1236. doi: 10.1097/PTS.0000000000001062. Epub 2022 Jul 21. PMID: 35858483; PMCID: PMC9722504.

Mohr NM, Okoro U, Harland KK, Fuller BM, Campbell K, Swanson MB, Wymore C, Faine B, Zepeski A, Parker EA, Mack L, Bell A, DeJong K, Mueller K, Chrischilles E, Carpenter CR, Wallace K, Jones MP, Ward MM. Outcomes Associated With Rural Emergency Department Provider-to-Provider Telehealth for Sepsis Care: A Multicenter Cohort Study. Ann Emerg Med. 2022 Oct 14:S0196-0644(22)00525-X. doi: 10.1016/j.annemergmed.2022.07.024. Epub ahead of print. PMID: 36253295.

Teran-Garza, Frida

Teran FA, Bravo E, Richerson GB. Sudden unexpected death in epilepsy: Respiratory mechanisms. Handb Clin Neurol. 2022;189:153-176. doi: 10.1016/B978-0-323-91532-8.00012-4. PMID: 36031303.

Van Ert, Hannah

Van Ert HA, Bohan DW, Rogers K, Fili M, Rojas Chávez RA, Qing E, Han C, Dempewolf S, Hu G, Schwery N, Sevcik K, Ruggio N, Boyt D, Pentella MA, Gallagher T, Jackson JB, Merrill AE, Knudson CM, Brown GD, Maury W, Haim H. Limited Variation between SARS-CoV-2-Infected Individuals in Domain Specificity and Relative Potency of the Antibody Response against the Spike Glycoprotein. Microbiol Spectr. 2022 Jan 26:e0267621. doi: 10.1128/spectrum.02676-21. Epub ahead of print. PMID: 35080430.

Voigt, Andrew P.

Mulfaul K, Mullin NK, Giacalone JC, Voigt AP, DeVore M, Stone EM, Tucker BA, Mullins RF. Local Factor H production by human choroidal endothelial cells mitigates complement deposition: implications for macular degeneration. J Pathol. 2022 Jan 17. doi: 10.1002/path.5867. Epub ahead of print. PMID: 35038170.

Voigt AP, Mullin NK, Mulfaul K, Lozano LP, Wiley LA, Flamme-Wiese MJ, Boese EA, Han IC, Scheetz TE, Stone EM, Tucker BA, Mullins RF. Choroidal Endothelial and Macrophage Gene Expression in Atrophic and Neovascular Macular Degeneration. Hum Mol Genet. 2022 Feb 19:ddac043. doi: 10.1093/hmg/ddac043. Epub ahead of print. PMID: 35181781.

Brockman QR, Scherer A, McGivney GR, Gutierrez WR, Voigt AP, Isaacson AL, Laverty EA, Roughton G, Knepper-Adrian V, Darbro B, Tanas MR, Stipp CS, Dodd RD. PRC2 loss drives MPNST metastasis and matrix remodeling. JCI Insight. 2022 Sep 6;. doi: 10.1172/jci.insight.157502. [Epub ahead of print] PubMed PMID: 36066973.

Mulfaul K, Russell JF, Voigt AP, Stone EM, Tucker BA, Mullins RF. The Essential Role of the Choriocapillaris in Vision: Novel Insights from Imaging and Molecular Biology. Annu Rev Vis Sci. 2022 Sep 15;8:33-52. doi: 10.1146/annurev-vision-100820-085958. PMID: 36108103.

den Hollander AI, Mullins RF, Orozco LD, Voigt AP, Chen HH, Strunz T, Grassmann F, Haines JL, Kuiper JJW, Tumminia SJ, Allikmets R, Hageman GS, Stambolian D, Klaver CCW, Boeke JD, Chen H, Honigberg L, Katti S, Frazer KA, Weber BHF, Gorin MB. Systems genomics in age-related macular degeneration. Exp Eye Res. 2022 Sep 12:109248. doi: 10.1016/j.exer.2022.109248. Epub ahead of print. PMID: 36108770.

Lehmann GL, Ginsberg M, Nolan DJ, Rodríguez C, Martínez-González J, Zeng S, Voigt AP, Mullins RF, Rafii S, Rodriguez-Boulan E, Benedicto I. Retinal Pigment Epithelium-Secreted VEGF-A Induces Alpha-2-Macroglobulin Expression in Endothelial Cells. Cells. 2022 Sep 24;11(19). doi: 10.3390/cells11192975. PubMed PMID: 36230937.

Voigt, Ellen M.

Kohlmeyer JL, Kaemmer CA, Lingo JJ, Voigt E, Leidinger MR, McGivney GR, Scherer A, Koppenhafer SL, Gordon DJ, Breheny P, Meyerholz DK, Tanas MR, Dodd RD, Quelle DE. Oncogenic RABL6A promotes NF1-associated MPNST progression in vivo. Neurooncol Adv. 2022 Apr 9;4(1):vdac047. doi: 10.1093/noajnl/vdac047. PMID: 35571990; PMCID: PMC9092646.

Koppenhafer SL, Goss KL, Voigt E, Croushore E, Terry WW, Ostergaard J, Gordon PM, Gordon DJ. Inhibitor of DNA binding 2 (ID2) regulates the expression of developmental genes and tumorigenesis in ewing sarcoma. Oncogene. 2022 May;41(20):2873-2884. doi: 10.1038/s41388-022-02310-0. Epub 2022 Apr 14. PMID: 35422476; PMCID: PMC9107507.

Wahlen, Madison M.

Wahlen MM, Schroeder MC, Johnson EC, Lizarraga IM, Engelbart JM, Tatman DJ, Wagi C, Charlton ME, Birken SA. Identifying Core Functions of an Evidence-Based Intervention to Improve Cancer Care Quality in Rural Hospitals. Front Health Serv. 2022;2:891574. doi: 10.3389/frhs.2022.891574. Epub 2022 Apr 28. PMID: 36188431; PMCID: PMC9524475.

Zhu, Eliot Y.

Zhu EY, Riordan JD, Vanneste M, Henry MD, Stipp CS, Dupuy AJ. SRC-RAC1 signaling drives drug resistance to BRAF inhibition in de-differentiated cutaneous melanomas. NPJ Precis Oncol. 2022 Oct 21;6(1):74. doi: 10.1038/s41698-022-00310-7. PubMed PMID: 36271142; PubMed Central PMCID: PMC9587254.