Arvand Asghari Khonakdari, PhD

Address: 3310C PBDBArvand Ashari photo
Phone: (319) 335-7660

Mentor: Matthew J. Potthoff, PhD

PhD Institution: University of Houston, 2021

Research Description

1. Role of FGF21 in Alzheimer’s disease

2. CNS regulation of body weight  


  • Outstanding Dissertation Award, University of Houston, 2021

  • College of Natural Sciences and Mathematics 3-Minute Thesis Competition Winner, University of Houston, 2020

  • Early Career Forum Travel Award, Endocrine Society, 2020

  • Robert Hazelwood Graduate Fellowship for Cancer Research, University of Houston, 2019

  • Travel Grant, Pan American Neuroendocrine Society, 2019

  • Presidential Fellowship Award, University of Houston, 2017-2019

  • College of Science Best Student Award, University of Tehran, Iran, 2014

  • Iran Ministry of Science Research and Technology Fellowship for Exceptional Talents, 2010-2016


  1. Asghari, A., Wall, K., Gill, M., Del Vecchio, N., Allahbakhsh, F., Wu, J., Deng, N., Zheng, W.J., Wu,       H., Umetani, M. and Maroufy, V., 2022. A novel group of genes that cause endocrine resistance in breast cancer identified by dynamic gene expression analysis. Oncotarget, 13, p.600.

  2. Matsubayashi, M., Sakaguchi, Y.M., Sahara, Y., Nanaura, H., Kikuchi, S., Asghari, A., Bui, L., Kobashigawa, S., Nakanishi, M., Nagata, R. and Matsui, T.K., 2021. 27‐Hydroxycholesterol regulates human SLC22A12 gene expression through estrogen receptor action. The FASEB Journal, 35(1), p.e21262.

  3. Asghari, A. and Umetani, M., 2020. Obesity and Cancer: 27-Hydroxycholesterol, the Missing Link. International Journal of Molecular Sciences, 21(14), p.4822.

  4. Maroufy, V., Shah, P., Asghari, A., Deng, N., Le, R.N., Ramirez, J.C., Yaseen, A., Zheng, W.J., Umetani, M. and Wu, H., 2020. Gene expression dynamic analysis reveals co-activation of Sonic Hedgehog and epidermal growth factor followed by dynamic silencing. Oncotarget, 11(15), p.1358.

  5. Asghari, A. And Umetani, M., 2020. ‘Estrogen Receptors and Obesity, with Focus on Adipose Tissues’, In Chen, G.G., Tong, M.C., van Hasselt, C.A., Estrogen Receptors: Structure, Functions and Clinical Aspects. Nova Science Publishers.

  6. Asghari, A., Hiramitsu, S., Ishikawa, T., Lee, W.R., Umetani, J., Korach, K.S. and      Umetani, M., 2019. The Cholesterol Metabolite 27-Hydroxycholesterol Promotes Adiposity via Estrogen Receptor Alpha Function. Endocrinology, 160(10), pp. 2485-2494.

  7. Hiramitsu, S., Ishikawa, T., Lee, W.R., Khan, T., Crumbley, C., Khwaja, N., Zamanian, F., Asghari, A., Sen, M., Zhang, Y. and Hawse, J.R., 2018. Estrogen Receptor Beta-Mediated Modulation of Lung Cancer Cell Proliferation by 27-Hydroxycholesterol. Frontiers in endocrinology, 9. p. 470.

  8. Asghari, A., Marashi, S.A. and Ansari-Pour, N., 2017. A sperm-specific proteome-scale metabolic network model identifies non-glycolytic genes for energy deficiency in asthenozoospermia. Systems biology in reproductive medicine, 63(2), pp. 100-112.