Jacob Rysted, PhD

Address: 2-440 BSBJacob Ryted photo 2019
Phone: (319) 335-6922
Email: jacob-rysted@uiowa.edu

Mentor: Deniz Atasoy, PhD

PhD Institution: University of Iowa, 2018

Research Description

Mechanisms of Mitochondrial Calcium Uptake


  • Multidisciplinary Lung Research Career Development Program (T32 HL007638), 2019-present
  • American Heart Association Predoctoral Fellowship (15PRE25310013), 2015-2017


  1. Rysted, J.E., Lin, Z., Walters, G.C., Rauckhorst, A.J., Noterman, M., Liu, G., Taylor, E.B., Strack, S., Usachev, Y.M.: Distinct Properties of Ca2+ Efflux from Brain, Heart and Liver Mitochondria: The Effects of Na+, Li+ and the Mitochondrial Na+/Ca2+ Exchange Inhibitor CGP37157. Cell Calcium, 96:102382, 2021.  PMCID: PMC8187304
  2. Hamilton, J., Brustovetsky, T., Rysted, J.E., Lin, Z., Usachev, Y.M. and Brustovetsky, N.: Deletion of mitochondrial calcium uniporter incompletely inhibits calcium uptake and induction of the permeability transition pore in brain mitochondria. J Biol Chem. 293(40):15652-63, 2018. PMCID: PMC6177608
  3. Kim, M.S., Shutov, L.P., Gnanasekaran, A., Lin, Z., Rysted, J.E., Ulrich, J.D., Usachev, Y.M.:  Nerve growth factor (NGF) regulates activity of nuclear factor of activated T-cells (NFAT) in neurons via the phosphatidylinositol 3-kinase (PI3K)-Akt-glycogen synthase kinase 3β (GSK3β) pathway.  J Biol Chem 289(45):31349-60, 2014.  PMCID: PMC4223335

Books / Chapters

  1. Rysted, J.E., Lin, Z. and Usachev, Y.M.  (2017)  Techniques for Simultaneous Mitochondrial and Cytosolic Ca2+ Imaging in Neurons.  In: Strack, S. and Usachev, Y. M. (eds) Techniques to Investigate Mitochondrial Function in Neurons, Vol. 123, Springer New York, New York.