Katelin Dannen, PhD
Introduction
Pharmacology (how drugs work) is a critical component of healthcare curriculums. Unfortunately, many students report that the subject is both daunting and confusing. Despite these negative reviews, very little research has been conducted to define the most effective pharmacology pedagogy. To address this deficiency, my research centers around developing active learning strategies that may be integrated into an often lecture-heavy pharmacology curriculum. Specifically, I am interested in assessing the potential benefits of application/critical thinking small group exercises and guided diagramming activities on student engagement with pharmacology material.
In addition to its critical role in healthcare curriculums, Pharmacology may also benefit students whose professions lie outside of healthcare. Drugs, both therapeutic and non-therapeutic, are common on college campuses. Student drug abuse also remains a concern on many campuses, including the University of Iowa. General pharmacology education in college may serve to create a culture of more educated consumers and to reduce drug misuse. Therefore, my research also seeks to address the extent to which elementary and advanced undergraduate pharmacology coursework influences student drug consumer knowledge and use.
Current Positions
- Assistant Professor of Neuroscience and Pharmacology
- Associate Chair for Education, Department of Neuroscience and Pharmacology
Education
- BA in Biology, Augustana College, Sioux Falls, SD
- PhD in Biology with an emphasis in Neurobiology, University of Iowa
- Postdoctoral Fellow in Department of Pharmacology, University of Iowa, Iowa City, Iowa, United States
Selected Publications
- Dannen, K. E. (2023). Critical Thinking Pharmacology Worksheets. Iowa Research Online (ISSN 2476-1680 (online)). *Received favorable peer review from MERLOT.
- Ahlers-Dannen, K. E.*, Yang, J.*, Fu, D., DeVore, A., Spicer, M. M., Fisher, R. A. (2023). A splice acceptor variant in RGS6 associated with intellectual disability, microcephaly, and cataracts disproportionately promotes expression of a subset of RGS6 isoforms. Journal of Human Genetics.
- Yang, J., DeVore, A., Fu, D., Spicer, M., Guo, M., Thompson, S., Ahlers-Dannen, K.E., Polato, F., Nussenzweig, A., Fisher, R.A. (2023) Rapid and precise genotyping of transgene zygosity in mice using an allele-specific method. Life Science Alliance.
- Ahlers-Dannen, K. E.*, Yang, J.*, Spicer, M. M., Maity, B., Stewart, A., Koland, J. G., Fisher, R. A. (2021). Protein profiling of RGS6, a pleiotropic gene implicated in numerous neuropsychiatric disorders, reveals multi-isoformic expression and a novel brain-specific isoform. eNeuro. Dec 7:ENEURO.0379-21.2021. doi: 10.1523/ENEURO.0379-21.2021. Epub ahead of print. PMID: 34880111 *Denotes co-first authors
- Chakravarti, B., Yang*, J., Ahlers-Dannen*, K. E., Luo, Z., Flaherty, H. A., Meyerholz, D. K., Anderson, M. E. & Fisher, R. A. (2017). Essentiality of RGS6 and Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II in Notch Signaling and Cardiovascular Development. J American Heart Association 6 (11). DOI: 10.1161/JAHA.117.007038. PMID: 29079565. PMCID: PMC5721783.
- Yang, J., Platt, L. T., Maity, B., Ahlers, K. E., Luo, Z., Lin, Z., Chakravarti, B., Ibeawuchi, S. R., Askeland, R. W., Bondaruk, J., Czerniak, B. A. & Fisher, R. A. (2016). RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation. Oncotarget 7 (43) 69159-69172. DOI: 10.18632/oncotarget.12473. PMID: 27713144. PMCID: PMC5342467.
- Ahlers, K. E., Karacay, B., Fuller, L., Bonthius, D. J. & Dailey, M. E. (2015). Transient activation of microglia following acute alcohol exposure in developing mouse neocortex is primarily driven by BAX-dependent neurodegeneration. Glia 63 (10) 1694-713. DOI: 10.1002/glia.22835. PMID: 25856413. PMCID: PMC4534325.
- Eyo, U., Miner, S., Ahlers, K., Wu, L. J. & Dailey, M. E. (2013). P2X7 receptor activation regulates microglial cell death during oxygen-glucose deprivation. Neuropharmacology 73 311-319. DOI: 10.1016/j.neuropharm.2013.05.032. PMID: 23770338. PMCID: 3786777.
- Ahlers, K. E., Chakravarti, B. & Fisher, R. A. (2016). RGS6 as a Novel Therapeutic Target in CNS Diseases and Cancer. AAPS J 18 (3) 560-72. DOI: 10.1208/s12248-016-9899-9. PMID: 27002730. PMCID: PMC5256616.