1. People

Christie Thomas, MBBS

Professor of Internal Medicine-Nephrology

Introduction

We have had a long standing and externally funded research program in fundamental biology that has had two broad areas of interest: the first is in the broad area of epithelial sodium transport in the distal nephron and the second is the area of sFlt1 biogenesis and regulation in the trophoblast and its function in the vasculature and in the kidney. We have a growing clinical interest in genetic kidney diseases and working with the Department of Pediatrics and the Genetic Counseling service, we have established a multidisciplinary Renal Genetics Clinic, a first for this region. In collaboration with the Iowa Institute of Human Genetics and Dr. Richard Smith, we have also helped developed the first comprehensive renal genetic panel using targeted genomic enrichment and massively parallel sequencing, called KidneySeq™. Our published works have reported on the usefulness of unbiased renal genetic screening for a variety of kidney diseases and have also demonstrated the role of a dedicated Renal Genetics Clinic in serving as a resource for the nephrology community.

Current Positions

  • Professor of Internal Medicine-Nephrology
  • Vice Chair for Faculty Advancement, Department of Internal Medicine
  • Medical Director, Kidney and Pancreas Transplantation, University of Iowa Hospitals & Clinics

Education

  • MBBS, Christian Medical College, Vellore, India
  • Resident, Nephrology and Transplantation, Royal Hallamshire and Northern General Hospitals (University of Sheffield), Sheffield, United Kingdom
  • Fellow, Nephrology, Case Western Reserve University and University Hospitals, Cleveland, Ohio

Graduate Program Affiliations

Center, Program and Institute Affiliations

Licenses & Certifications

  • Medical License, Iowa Board of Medicine
  • Diplomate, American Board of Internal Medicine
  • Diplomate, American Board of Internal Medicine, Nephrology
  • Member, Royal College of Physicians UK

Selected Publications

  • Doshi, M. D., Gordon, E. J., Freedman, B. I., Glover, C., Locke, J. E. & Thomas, C. P. (2021). Integrating APOL1 Kidney-risk Variant Testing in Live Kidney Donor Evaluation: An Expert Panel Opinion. Transplantation 105 (10) 2132-2134. DOI: 10.1097/TP.0000000000003641. PMID: 33534524. PMCID: PMC8994118.
  • Dollard, S. C., Annambhotla, P., Wong, P., Meneses, K., Amin, M. M., La Hoz, R. M., Lease, E. D., Budev, M., Arrossi, A. V., Basavaraju, S. V. & Thomas, C. P. (2020). Donor-derived human herpesvirus 8 and development of Kaposi sarcoma among 6 recipients of organs from donors with high-risk sexual and substance use behavior. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. DOI: 10.1111/ajt.16181. PMID: 32633035.
  • Mashmoushi, A., Choudhary, A., Thomas, C. P. & Wolf MTF (2020). A rare case of hyporeninemic hypertension: Answers. Pediatric nephrology (Berlin, Germany). DOI: 10.1007/s00467-020-04667-4. PMID: 32607771.
  • Mashmoushi, A., Choudhary, A., Thomas, C. P. & Wolf MTF (2020). A rare case of hyporeninemic hypertension: Questions. Pediatric nephrology (Berlin, Germany). DOI: 10.1007/s00467-020-04658-5. PMID: 32607770.
  • Thomas, C. P., Freese, M. E., Ounda, A., Jetton, J. G., Holida, M., Noureddine, L. & Smith, R. J. (2020). Correction: Initial experience from a renal genetics clinic demonstrates a distinct role in patient management. Genetics in medicine : official journal of the American College of Medical Genetics. DOI: 10.1038/s41436-020-01000-0. PMID: 33024316.
  • Mandelbrot, D. A., Reese, P. P., Garg, N., Thomas, C. P., Rodrigue, J. R., Schinstock, C., Doshi, M., Cooper, M., Friedewald, J., Naik, A. S., Kaul, D. R., Ison, M. G., Rocco, M. V., Verbesey, J., Hladunewich, M. A., Ibrahim, H. N. & Poggio, E. D. (2020). KDOQI US Commentary on the 2017 KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors. American journal of kidney diseases : the official journal of the National Kidney Foundation 75 (3) 299-316. DOI: 10.1053/j.ajkd.2019.10.005. PMID: 32007233.
  • Kumar, A., Howard, A. & Thomas, C. P. (2020). Estimated Glomerular Filtration Rate at Transplant Listing and Other Predictors of Post-Heart Transplant Mortality and the Development of ESRD. Transplantation. DOI: 10.1097/TP.0000000000003159. PMID: 32028343.
  • Crow, L. D., Jambusaria-Pahlajani, A., Chung, C. L., Baran, D. A., Lowenstein, S. E., Abdelmalek, M., Ahmed, R. L., Anadkat, M. J., Arcasoy, S. M., Berg, D., Bibee, K. P., Billingsley, E., Black, W. H., Blalock, T. W., Bleicher, M., Brennan, D. C., Brodland, D. G., Brown, M. R., Carroll, B. T., Carucci, J. A., Chang, T. W., Chaux, G., Cusack, C. A., Dilling, D. F., Doyle, A., Emtiazjoo, A. M., Ferguson, N. H., Fosko, S. W., Fox, M. C., Goral, S., Gray, A. L., Griffin, J. R., Hachem, R. R., Hall, S. A., Hanlon, A. M., Hayes, Jr, D., Hickey, G. W., Holtz, J., Hopkins, R. S., Hu, J., Huang, C. C., Jiang SIB, Kapnadak, S. G., Kraus, E. S., Lease, E. D., Leca, N., Lee, J. C., Leitenberger, J. J., Lim, M. A., Longo, M. I., Malik, S. M., Mallea, J. M., Menter, A., Myers, S. A., Neuburg, M., Nijhawan, R. I., Norman, D. J., Otley, C. C., Paek, S. Y., Parulekar, A. D., Patel, M. J., Patel, V. A., Patton, T. J., Pugliano-Mauro, M., Ranganna, K., Ravichandran, A. K., Redenius, R., Roll, G. R., Samie, F. H., Shin, T., Singer, J. P., Singh, P., Soon, S. L., Soriano, T., Squires, R., Stasko, T., Stein, J. A., Taler, S. J., Terrault, N. A., Thomas, C. P., Tokman, S., Tomic, R., Twigg, A. R., Wigger, M. A., Zeitouni, N. C. & Arron, S. T. (2019). Initial Skin Cancer Screening for Solid Organ Transplant Recipients in the United States: Delphi Method Development of Expert Consensus Guidelines. Transplant international : official journal of the European Society for Organ Transplantation. DOI: 10.1111/tri.13520. PMID: 31502728.
  • Myaskovsky, L., Kendall, K., Li, X., Chang, C. H., Pleis, J. R., Croswell, E., Ford, C. G., Switzer, G. E., Langone, A., Mittal-Henkle, A., Saha, S., Thomas, C. P., Adams Flohr, J., Ramkumar, M. & Dew, M. A. (2019). Unexpected Race and Ethnicity Differences in the U.S. National Veterans Affairs Kidney Transplant Program. Transplantation. DOI: 10.1097/TP.0000000000002905. PMID: 31397801.
  • Tietjen, A., Hays, R., McNatt, G., Howey, R., Lebron-Banks, U., Thomas, C. P. & Lentine, K. L. (2019). Billing for living kidney donor care: Balancing cost recovery, regulatory compliance, and minimized donor burden. Current transplantation reports 6 (2) 155-166. DOI: 10.1007/s40472-019-00239-0. PMID: 31214485. PMCID: PMC6580854.

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