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Matthew D. Karam, MD

Guy and Anita Frumson Professor in Orthopedic Surgery
Residency Director
Vice Chair of Education
Clinical Associate Professor of Orthopedics and Rehabilitation

Contact Information

Primary Office
01019 Colloton Pavilion (JCP)
Iowa City, IA 52242


BS, University of Iowa
MD, Medicine, The Chicago Medical School
Fellow, Orthopaedic Trauma, Hennepin County Medical Center
Resident, Orthopaedic Surgery, University of Iowa Hospitals and Clinics

Licensure and Certifications

Part II American Board of Orthopaedic Surgery
State of Iowa Medical License
Part I American Board of Orthopaedic Surgery

Research Summary

Since joining the faculty in 2011 I have focused my research interests primarily on surgical skills education and surgical simulation techniques. I work collaboratively with multiple labs and groups here at the University of Iowa including our Orthopaedics Biomechanics Laboratory and Human Factors Laboratory in the Department of Engineering. We currently have multiple grants investigating surgical simulations techniques in articular-fracture management, wire navigation with a radiation-free wire navigation simulator, image interpretation, and surgical video capture for use in resident education. Given the current status of graduate medical education with restricted work hours and increased levels of transparency, techniques to ensure surgical proficiency will be increasingly required. It is with this goal in mind, that this line of research is fascinating to me. In the Department of Orthopaedics we have initiated and with great success, began a surgical skills curriculum for PGY-1 resident learners. My goal will be to develop assessment techniques to train junior level learners on skills that will enhance patient safety. I will continue to perform this research within the Department of Orthopaedics and collaborate with multiple groups within our institution at large; including the above mentioned laboratories as well as the UIHC Graduate Medical Education office, the office of Consultation in Research and Medical Education and the Carver College of Medicine.


Long, S., Thomas, G. W., Karam, M. D., Marsh, J. L. & Anderson, D. D. (In Press). Surgical Skill Can be Objectively Measured From Fluoroscopic Images Using a Novel Image-based Decision Error Analysis (IDEA) Score. pp. 1-9. Clinical Orthopaedics and Related Research, The Association of Bone and Joint Surgeons. PMID: 33399401.

Shamrock, A. G., Khazi, Z., Gulbrandsen, T. R., Duchman, K. R., Willey, M. C., Karam, M. D., Hogue, M. H. & Marsh, J. L. (2020). Trends and Complications of Arthroscopic-Assisted Tibial Plateau Fracture Fixation: A Matched Cohort Analysis. Arthroscopy, sports medicine, and rehabilitation, 2(5), e569-e574. PMID: 33134996.

Anthony, C. A., Rojas, E. O., Keffala, V., Glass, N. A., Shah, A. S., Miller, B. J., Hogue, M., Willey, M. C., Karam, M. & Marsh, J. L. (2020). Acceptance and Commitment Therapy Delivered via a Mobile Phone Messaging Robot to Decrease Postoperative Opioid Use in Patients With Orthopedic Trauma: Randomized Controlled Trial. Journal of medical Internet research, 22(7), e17750. PMID: 32723723.

Thomas, G., Long, S., Tatum, M., Kowalewski, T., Mattioli, D., Marsh, J., Kowalski, H., Karam, M., Bechtold, J. & Anderson, D. (2020). A Vision For Using Simulation & Virtual Coaching To Improve The Community Practice Of Orthopedic Trauma Surgery. The Iowa Orthopedic Journal, 40(1), 25-34.

Karam, M. D., Marsh, J. (2020). Classification of Fractures. In Rockwood and Green's Fractures in Adults. (9th Edition), pp. 104-122. Philadelphia: Wolters Kluwer.

Thomas, G. W., Long, S., Tatum, M., Kowalewski, T., Mattioli, D., Marsh, J. L., Kowalski, H. R., Karam, M. D., Bechtold, J. E. & Anderson, D. D. (2020). A Vision for Using Simulation & Virtual Coaching to Improve the Community Practice of Orthopedic Trauma Surgery. The Iowa orthopaedic journal, 40(1), 25-34. PMID: 32742205.

Hancock, K. J., Rice, O. M., Anthony, C. A., Glass, N., Hogue, M., Karam, M., Marsh, J. L. & Willey, M. C. (2019). Efficacy of Multimodal Analgesic Injections in Operatively Treated Ankle Fractures: A Randomized Controlled Trial. Journal of Bone and Joint Surgery - American Volume, 101(24), 2194-2202. DOI: 10.2106/JBJS.19.00293.

Cychosz, C., Khazi, Z. M., Karam, M., Duchman, K., Willey, M. & Westermann, R. (2019). Validation of a novel hip arthroscopy simulator: establishing construct validity. Journal of Hip Preservation Surgery, 6(4), 385-389. PMID: 32015891.

Karam, M., Marsh, J., Long, S., Anderson, D. & Thomas, G. (2019). Looking Beyond the Tip-Apex Distance to Assess Wire Navigation Performance. In American Orthopaedic Association's (AOA) Council of Orthopaedic Residency Directors (CORD) Summer 2018 Conference: Top Abstracts. (Vols. 00-A). (00) The Journal of Bone & Joint Surgery.

Tofte, J. N., Rojas, E. O., Anthony, C. A., Holte, A. J., Volkmar, A., Karam, M. D., Caldwell, L. S. & Lawler, E. A. (2019). Intraoperative Point of View Video Capture and Surgical Segmentation in Carpal Tunnel Release: A Feasibility Analysis. Journal of surgical education. PMID: 31221605.

Plumarom, Y., Wilkinson, B. G., Marsh, J. L., Willey, M. C., An, Q., Gao, Y. & Karam, M. D. (2019). Radiographic Healing of Far Cortical Locking Constructs in Distal Femur Fractures: A Comparative Study With Standard Locking Plates. Journal of orthopaedic trauma, 33(6), 277-283. PMID: 30908342.

Long, S. A., Thomas, G., Karam, M. D. & Anderson, D. D. (2019). Do Skills Acquired from Training with a Wire Navigation Simulator Transfer to a Mock Operating Room Environment?. Clinical Orthopaedics and Related Research. PMID: 31135546.

Goetz, J. E., Szabo, N., Rudert, M. J., Karam, M. D. & Phisitkul, P. (2019). Achilles Tension Mitigates Fibular Malalignment Measured in Cadaveric Studies of Syndesmotic Clamping. Foot & ankle international, 40(4), 465-474. PMID: 30623692.

Carender, C. N., Shamrock, A. G. & Karam, M. D. (2019). Variability in Experience Performing Lower Extremity Amputations between Surgical Residents: an Examination of ACGME Case Logs. Iowa Orthopedic Journal, 39.

Karam, M. D., Agel, J., Marmor, M., Marsh, J. L., Kellam, J. F. & Meinberg, E. (2018). Letter Regarding: Orthopaedic Trauma Association Fracture and Dislocation Classification Compendium. Foot & ankle international, 39(12), 1509. PMID: 30500319.

Goetz, J. E., Davidson, N. P., Rudert, M. J., Szabo, N., Karam, M. D. & Phisitkul, P. (2018). Biomechanical Comparison of Syndesmotic Repair Techniques During External Rotation Stress. Foot & ankle international, 39(11), 1345-1354. PMID: 30005173.

Shinozaki, G., Chan, A., Sparr, N., Zarei, K., Gaul, L., Heinzman, J., Robles, J., Yuki, K., Chronis, T., Ando, T., Wong, T., Sabbagh, S., Weckmann, M., Lee, S., Yamada, T., Karam, M., Noiseux, N., Shinozaki, E. & Cromwell, J. (2018). Delirium detection by a novel bispectral EEG device in general hospital. Psychiatry Clinical Neuroscience. PMID: 30246448.

Osborn, P. M., Ames, S. E., Turner, N. S., Caird, M. S., Karam, M. D., Mormino, M. A. & Krueger, C. A. (2018). An Analysis of Research Quality and Productivity at Six Academic Orthopaedic Residencies. Journal of Surgical Education. PMID: 29884523.

Taylor, L., Thomas, G., Anderson, D., Marsh, J. & Karam, M. (2018). Measures of Hip Fracture Wire Navigation Performance in the Operating Room Reflect Surgical Experience. The Journal of Bone and Joint Surgery, e68(1).

Taylor, L. K., Thomas, G. W., Karam, M. D., Kreiter, C. D. & Anderson, D. D. (2018). Developing an objective assessment of surgical performance from operating room video and surgical imagery. IISE Transactions on Healthcare Systems Engineering, 8(2), 110-116.

Karam, M. D., Marsh, J. (2018). Faculty Development. In P. J. Dougherty , B. L. Joyce (Eds.) The Orthopedic Educator: A Pocket Guide. Springer.

Kellam, J. F., Meinberg, E. G., Agel, J., Karam, M. D. & Dirschl, D. R. (2018). Introduction: Fracture and Dislocation classification Compendium- 2018: International Comprehensive classification of Fractures and Dislocations Committee. Journal of Orthopedic Trauma, S1. PMID: 29256945.

Tantavisut, S., Tofte, J. N., Westerlind, B. O., Karam, M. D., Phisitkul, P. & Marsh, J. L. (2018). Efficacy and Validation of a Simulation-Based Compartment Syndrome Instructional Course. The Iowa orthopaedic journal, 38, 113-121. PMID: 30104933.

Meinberg, E. G., Agel, J., Roberts, C. S., Karam, M. D. & Kellam, J. F. (2018). Fracture and Dislocation Classification Compendium-2018. Journal of orthopaedic trauma, 32 Suppl 1, S1-S170. PMID: 29256945.

Petravick, M. E., Marsh, J. L., Karam, M. D. & Dirschl, D. R. (2018). A Survey on Recent Medical School Graduate Comfort With the Level 1 Milestones. Journal of surgical education, 75(4), 911-917. PMID: 29127019.

Tomas, G., Williams, L., Anderson, D., Karam, M., Kreiter, C. & Alfaro, A. (2017). Developing an Objective Assessment of Surgical Performance from Operating Room Video and Surgical Imagery.

Buckwalter V, J., Westermann, R., Mooers, B., Karam, M. & Wolf, B. (2017). Timing of Surgical Reduction and Stabilization of Talus Fracture-Dislocations. The American Journal of Orthopedics, 46(6), E408-E413. PMID: 29309454.

Camp, C. L., Degen, R. M., Hanssen, A. D., Dines, J. S., Karam, M. D. & Turner, N. S. (2017). Residents and Program Director Perspectives Often Differ on Optimal Preparation Strategies and the Value of the Orthopedic In-Training Examination. Journal of Surgical Education. PMID: 28673803.

Tantavisut, S., Phisitkul, P., Westerlind, B. O., Gao, y., Karam, M. & Marsh, J. L. (2017). Percutaneous Reduction and Screw Fixation of Displaced Intra-articular Fractures of the Calcaneus. Foot & Ankle International, 38(4), 367-374. PMID: 27852648.

Willey, M. C., Karam, M. D. & Marsh, J. (2017). Open Reduction Internal Fixation of Tibial Plateau Fractures. In R. M. Frank , B. Forsythe & M. T. Provencher (Eds.) Case Competencies in Orthopaedic Surgery. pp. 264-278. Philadelphia, PA: Elsevier.

Buckwalter, J., Wolf, B., Karam, M., Westermann, R. & Mooers, B. (2017). Timing of Surgical Reduction of Talar Fracture-Dislocations: Does Timing From Injury to Surgical Reduction of Talus Fracture-Dislocations Matter?. The American Journal of Orthopedics.

Hanley, J., Warren, D., Glass, N., Tranel, D., Karam, M. & Buckwalter, J. (2017). Visual Interpretation of Plain Radiographs in Orthopaedics Using Eye-Tracking Technology. Iowa Orthopedic Journal, 37, 225-231. PMID: 28852362.

Phruetthiphat, O., Willey, M., Karam, M. D., Gao, Y., Westerlind, B. & Marsh, J. (2017). Comparison of Outcomes and Complications of Isolated Acetabular Fractures and Acetabular Fractures With Associated Injuries. Journal of Orthopaedic Trauma, 31(1), 31-36. PMID: 27749508.

Phruetthiphat, O. A., Koehler, D. M., Karam, M. D., Rungprai, C., Gao, Y. & Marsh, J. L. (2016). Preinjury Aerobic Fitness Predicts Postoperative Outcome and Activity Level After Acetabular Fracture Fixation. Journal of Orthopaedic Trauma, 30(8), 267-72. PMID: 26913596.

Karam, M., Marsh, J. (2016). Proximal Tibia Fractures. In C. Court-Brown , M. McQueen , M. F. Swiontkowski , D. Ring , S. M. Friedman , A. D. Duckworth (Eds.) Musculoskeletal Trauma in the Elderly. CRC Press.

Johnson, J. P., Karam, M. D., Schisel, J. & Agel, J. (2016). An evaluation of the OTA-OFC system in clinical practice: A multi-center study with 90 day outcomes. Journal of Orthopaedic Trauma. PMID: 27392160.

Camp, C. L., Sousa, P. L., Hanssen, A. D., Karam, M. D., Haidukewych, G. J., Oakes, D. A. & Turner, N. S. (2016). Orthopedic Surgery Applicants: What They Want in an Interview and How They Are Influenced by Post-Interview Contact. Journal of Surgical Education, 73(4), 709-14. PMID: 27137662.

(METRC), M. (2016). Building a Clinical Research Network in Trauma Orthopaedics: The Major Extremity Trauma Research Consortium (METRC). Journal of Orthopaedic Trauma, 30(7), 353-361. PMID: 27333458.

Camp, C. L., Sousa, P. L., Hanssen, A. D., Karam, M. D., Haidukewych, G. J., Oakes, D. A. & Turner, N. S. (2016). The Cost of Getting Into Orthopedic Residency: Analysis of Applicant Demographics, Expenditures, and the Value of Away Rotations. Journal of Surgical Education. PMID: 27184179.

Taylor, L. K., Thomas, G. W., Karam, M. D., Kreiter, C. D. & Anderson, D. D. (2016). Assessing Wire Navigation Performance in the Operating Room. Journal of Surgical Education. PMID: 27184177.

Willey, M., Karam, M. (2016). Impact of Infection on Fracture Fixation. Orthopedic Clinics of North America, 47(2), 357-364. PMID: 26772944.

Anderson, D. D., Long, S., Thomas, G. W., Putnam, M. D., Bechtold, J. E. & Karam, M. D. (2016). Objective Structured Assessments of Technical Skills (OSATS) Does Not Assess the Quality of the Surgical Result Effectively. Clinical Orthopaedics and Related Research, 474(4), 874-881. PMID: 26502107.

Karam, M. D., Thomas, G. W., Taylor, L., Liu, X., Anthony, C. & Anderson, D. (2016). Value Added: the Case for Point-of-View Camera use in Orthopedic Surgical Education. The Iowa Orthopaedic Journal, 36, 7-12. PMID: 27528828.

Thomas, G. W., Rojas-Murillo, S., Hanley, J. M., Kreiter, C. D., Karam, M. D. & Anderson, D. D. (2016). Skill Assessment in the Interpretation of 3D Fracture Patterns from Radiographs. The Iowa Orthopaedic Journal, 36, 1-6. PMID: 27528827.

Oteror, J. E., Tantavisut, S., Karam, M. D., Phisitkul, P., Akoh, C. C., Goa, Y. & Marsh, J. L. (2015). There is Poor Reliability of Bohler’s Angle and the Crucial angle of Gissane in Assessing Displaced Intra-articular Calcaneal Fractures. Foot and Ankle Surgery, 21(4), 277-81. PMID: 26564731.

Ivestigators, F., Bhandari, M., Jeray, K., Petrisor, B., Devereaux, P., Heels-Ansdell, D., Schemitsch, E., Anglen, J., Della Rocca, G., Kreder, H., Liew, S., McKay, P., Papp, S., Sancheti, P., Sprague, S., Stone, T., Sun, X., Tanner, S., Torentta III, P., Tufescu, T., Walter, S., Guyatt, G. & Karam, M. (2015). A Trial of Wound Irrigation in the Initial Management of Open Fracture Wounds. The New England Journal of Medicine, 373(27), 2629-41. PMID: 26361448.

Kho, J. Y., Johns, B. D., Thomas, G. W., Karam, M. D., Marsh, J. & Anderson, D. D. (2015). A Hybrid Reality Radiation-free Simulator for Teaching Wire Navigation Skills. Journal of Orthopaedic Trauma. PMID: 26165262.

Karam, M. D., Thomas, G. W., Koehler, D. M., Westerlind, B. O., Lafferty, P. M., Ohrt, G. T., Marsh, J., Van Heest, A. E. & Anderson, D. D. (2015). Surgical Coaching from Head-Mounted Video in the Training of Fluoroscopically Guided Articular Fracture Surgery. Journal of Bone and Joint Surgery, 97(12), 1031-1039. PMID: 26085538.

Camp, C., Martin, J., Karam, M. D., Ryssman, D. & Turner, N. (2015). Orthopaedic Surgery Residents and Program Directors Agree on How Time Is Currently Spent in Training and Targets for Improvement. Clinical Orthopaedics and Related Research. PMID: 25809874.

Buckwalter, J., Westerlind, B. & Karam, M. D. (2015). Asymmetric Bilateral Hip Dislocations: A Case Report and Historical Review of the Literature. Iowa Orthopaedic Journal, 35(2015), 70-91. PMID: 26361448.

Santoro, D., Tantavisut, S., Aloj, D. & Karam, M. D. (2014). Diaphyseal Osteotomy After Post-Traumatic Malalignment. Current Reviews in Musculoskeletal Medicine, 7(4), 312-322. PMID: 25270959.

Miller, B. J., Callaghan, J. J., Cram, P., Karam, M. D., Marsh, J. & Noiseux, N. O. (2014). Changing Trends in the Treatment of Femoral Neck Fractures: A Review of the American Board of Orthopaedic Surgery Database. Journal of Bone and Joint Surgery, 96A(17). PMID: 25187593.

Westerlind, B., Karam, M. D., Anderson, D., Yehyawi, T., Kho, J. & Marsh, J. L. (2014). A Surgical Skills Training Curriculum for PGY-1 Residents: AAOS Exhibit Selection. Journal of Bone and Joint Surgery, 96(16), 140-146. PMID: 25143508.

Akoh, C. C., Schick, C., Otero, J. & Karam, M. D. (2014). Fat Embolism Syndrome After Femur Fracture Fixation: a Case Report. The Iowa Orthopaedic Journal, 34, 55-62. PMID: 25328460.

Marsh, J. L., Karam, M. D. (2014). Tibial Plateau Fractures. In C. M. Court-Brown , J. D. Heckman , M. M. McQueen , W. M. Ricci , P. Tornetta III (Eds.) Rookwood and Green's Fractures in Adults. (8), pp. 2303-2368. Philadelphia, PA: Wolters Kluwer.

Yehyawi, T., Thomas, T. P., Ohrt, G. T., Marsh, J. L., Karam, M. D., Brown, T. D. & Anderson, D. D. (2013). A Simulation Trainer for Complex Articular Fracture Surgery. Journal of Bone and Joint Surgery, 95(13), e92. PMID: 23824397.

Karam, M. D., Pedowitz, R. A., Natividad, H., Murray, J. & Marsh, J. L. (2013). Current and Future use of Surgical Skills Training Laboratories in Orthopaedic Resident Education: a National Survey. Journal of Bone and Joint Surgery, 95(1), e4. PMID: 23283381.

Karam, M. D., Westerlind, B., Anderson, D. D., Marsh, J. L. & UI Orthopaedic Surgical Skills Training Committee Corresponding, (2013). Development of an Orthopaedic Surgical Skills Curriculum for Post-graduate Year One Resident Learners - the University of Iowa Experience. Iowa Orthopaedic Journal, 33, 178-84. PMID: 24027480.

Karam, M. D., Templemen, D. C. (2013). Diastasis of the Symphysis Pubis: Open Reduction Internal Fixation. In D. A. Wiss (Eds.) Master Techniques in Orthopaedic Surgery: Fractures. (Third), pp. 771-780. Philadelphia, PA: Wolters Kluwer, Lippincott Williams & Wilkins.

Gao, Y., Pugely, A., Karam, M. D., Phisitkul, P., Mendoza, S. & Johnston, R. C. (2013). Is Hospital Teaching Status a Key Factor in Hospital Charge for Children with Hip Fractures?: Preliminary Findings From KID Database. Iowa Orthopaedic Journal, 33, 130-5. PMID: 24027472.

Karam, M., Templemen, D. (2013). Pelvic Ring Injury II. In M. K. Sethi , A. A. Jahangir , W. T. Obremskey (Eds.) Orthopaedic Traumatology. pp. 195-206. New York, NY: Springer.

Karam, M. D., Schmidt, A. H. (2013). Proximal Humerus Fractures. In D. J. Hak , K. R. Ipaktchi , S. J. Morgan (Eds.) Orthopedic Trauma Call for the Attending Surgeon. pp. 131-138. Thorofare, NJ: SLACK Incorporated.

Karam, M. D., Kho, J., Yehyawi, T., Ohrt, T., Thomas, G. W., Anderson, D. D. & Marsh, J. L. (2012). Application of Surgical Skills Simulation Training and Assessment in Orthopaedic Trauma. Iowa Orthopaedic Journal, 32, 76-82. PMID: 23576925.

Marsh, J. L., Kho, J. Y., Karam, M. D. & Westerlind, B. O. (2012). Fluoroscopic Knowledge and Skills. In Yes. Chapel Hill, NC: ABOS Surgical Skills Modules for PGY-1 Residents; ABOS.org.

Karam, M. D., Marsh, J. & Westerlind, B. O. (2012). Principles and Techniques of Fracture Reduction. In Yes. Chapel Hill, NC: ABOS Surgical Skills Modules for PGY-1 Residents; ABOS.org.

Karam, M. D., Marsh, J. L. & Westerlind, B. O. (2012). Techniques Basic to Internal Fixation of Fractures. ABOS Surgical Skills Modules for PGY-1 Residents; ABOS.org.

Marsh, J. L., Boyer, J. S., Sullivan, J., Phisitkul, P. & Karam, M. D. (2011). A Percutaneous Technique for Reduction and Internal Fixation of Displaced Intra-Articular Calcaneal Fractures. JBJS Essential Surgical Techniques, 1(2), 1-12. DOI: http://dx.doi.org/10.2106/JBJS.ST.K.00016.

Karam, M. D., Gao, Y. & McKinley, T. (2011). Assessment of Walking Pattern Pre and Post Peri-Acetabular Osteotomy. Iowa Orthopaedic Journal, 31, 83-89. PMID: 22096426.

Karam, M. D., Pugely, A., Callaghan, J. J. & Shurr, D. (2011). Hinged Cast Brace for Persistent Flexion Contracture Following Total Knee Replacement. Iowa Orthopaedic Journal, 31, 69-72. PMID: 22096423.

Karam, M., Marsh, J. L. (2010). Does a Trauma Course Improve Resident Performance on the Trauma Domain of the OITE?. Journal of Bone and Joint Surgery, 92(13), e19 1-5. PMID: 20926717.

Gao, Y., Johnston, R. & Karam, M. (2010). Pediatric Sports-Related Lower Extremity Fractures: Hospital Length of stay and Charges: What is the Role of the Primary Payer?. Iowa Orthopaedic Journal, 30, 115-119. PMID: 21045983.

Karam, M., Amendola, A. & Mendoza, S. A. (2010). Successful Treatment of Acute Exertional Paraspinal Compartment Syndrome with Hyperbaric Oxygen Therapy. Iowa Orthopaedic Journal, 30, 188-190. PMID: 21045996.

Karam, M., Willey, M. & Shurr, D. (2010). Total Knee Replacement in Patients with Below-Knee Amputations. Iowa Orthopaedic Journal, 30, 150-152. PMID: 21045987.

Karam, M., McKinley, T. (2008). Traumatic Heterotopic Ossification of the Quadratus Lumborum: A Case Report. Iowa Orthopaedic Journal, 28, 88-91. PMID: 19223956.

Brand, R. A., Karam, M. (2003). The Number and the Scope of Activity of the Orthopaedic Clinician Scientists in the United States. Journal of Bone and Joint Surgery, 85(2), 374-379. PMID: 12571319.

Brand, R. A., Karam, M. & Coutts, M. D. (2002). The Estimated Costs of Manuscripts Associated with OREF Funding. Journal of Bone and Joint Surgery, 84(8), 1470-1472. PMID: 12177279.