Mitchell C. Coleman, PhD

Portrait
Research Assistant Professor of Orthopedics and Rehabilitation

Contact Information

Primary Office
1182 Medical Laboratories
Iowa City, IA 52242
319-335-7550

Education

BSE, Biomedical Engineering, University of Iowa
BA, Religious Studies, University of Iowa
MA, Religious Studies, University of Iowa
PhD, Free Radical and Radiation Biology, University of Iowa
Postdoctoral Scholar, Orthopaedics, University of Iowa Carver College of Medicine

Education/Training Program Affiliations

Free Radical and Radiation Biology Graduate Program

Publications

Coleman, M. C., Brouillette, M. J., Andresen, N. S., Oberley-Deegan, R. E. & Martin, J. A. (2017). Differential Effects of Superoxide Dismutase Mimetics after Mechanical Overload of Articular Cartilage. Antioxidants (Basel Switzerland), 6(4). PMID: 29189731.

Coleman, M. C., Goetz, J. E., Brouillette, M. J., Seol, D., Willey, M. C., Petersen, E. B., Anderson, D. D., Hendrickson, N. R., Compton, J., Khorsand, B., Morris, A. S., Salem, A. K., Fredericks, D. C., McKinley, T. O. & Martin, J. A. (In Press). Mitochondrial Responses to Intraarticular Fracture are a Disease-Modifying Target for Post-Traumatic Osteoarthritis Prevention. Science Translational Medicine.

Goetz, J. E., Coleman, M. C., Fredericks, D. C., Petersen, E. B., Martin, J. A., McKinley, T. O. & Tochigi, Y. (2017). Time-dependent loss of mitochondrial function precedes progressive histologic cartilage degeneration in a rabbit meniscal destabilization model. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 35(3), 590-9. PMID: 27279147.

Coleman, M. C., Ramakrishnan, P. S., Brouillette, M. J. & Martin, J. A. (2016). Injurious Loading of Articular Cartilage Compromises Chondrocyte Respiratory Function. Arthritis & rheumatology (Hoboken, N.J.), 68(3), 662-71. PMID: 26473613.

Coleman, M. C., Olivier, A. K., Jacobus, J. A., Mapuskar, K. A., Mao, G., Martin, S. M., Riley, D. P., Gius, D. & Spitz, D. R. (2014). Superoxide mediates acute liver injury in irradiated mice lacking sirtuin 3. Antioxidants & redox signaling, 20(9), 1423-35. PMID: 23919724.

Jacobus, J. A., Duda, C. G., Coleman, M. C., Martin, S. M., Mapuskar, K., Mao, G., Smith, B. J., Aykin-Burns, N., Guida, P., Gius, D., Domann, F. E., Knudson, C. M. & Spitz, D. R. (2013). Low-dose radiation-induced enhancement of thymic lymphomagenesis in Lck-Bax mice is dependent on LET and gender. Radiation research, 180(2), 156-65. PMID: 23819597.

Tao, R., Coleman, M. C., Pennington, J. D., Ozden, O., Park, S. H., Jiang, H., Kim, H. S., Flynn, C. R., Hill, S., Hayes McDonald, W., Olivier, A. K., Spitz, D. R. & Gius, D. (2010). Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress. Molecular cell, 40(6), 893-904. PMID: 21172655.

Coleman, M. C., Asbury, C. R., Daniels, D., Du, J., Aykin-Burns, N., Smith, B. J., Li, L., Spitz, D. R. & Cullen, J. J. (2008). 2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer. Free radical biology & medicine, 44(3), 322-31. PMID: 18215740.