Christopher S. Stipp, PhD
Professor of Biology
Current Positions
- Associate Professor of Biology
- Associate Professor of Molecular Physiology and Biophysics
Education
- BS in Biochemistry, Indiana University
- PhD in Biology, Massachusetts Institute of Technology
Graduate Program Affiliations
Selected Publications
- Vanneste, M., Feddersen, C. R., Varzavand, A., Zhu, E. Y., Foley, T., Zhao, L., Holt, K. H., Milhem, M., Piper, R., Stipp, C. S., Dupuy, A. J. & Henry, M. D. (2020). Functional Genomic Screening Independently Identifies CUL3 as a Mediator of Vemurafenib Resistance via Src-Rac1 Signaling Axis. Frontiers in oncology 10 442. PMID: 32346533. DOI: 10.3389/fonc.2020.00442.
- Kluz, P. N., Kolb, R., Xie, Q., Borcherding, N., Liu, Q., Luo, Y., Kim, M. C., Wang, L., Zhang, Y., Li, W., Stipp, C., Gibson-Corley, K. N., Zhao, C., Qi, H. H., Bellizzi, A., Tao, A. W., Sugg, S., Weigel, R. J., Zhou, D., Shen, X. & Zhang, W. (2020). Cancer cell-intrinsic function of CD177 in attenuating β-catenin signaling. Oncogene 39 (14) 2877-2889. PMID: 32042113. DOI: 10.1038/s41388-020-1203-x.
- Moose, D. L., Krog, B. L., Kim, T. H., Zhao, L., Williams-Perez, S., Burke, G., Rhodes, L., Vanneste, M., Breheny, P., Milhem, M., Stipp, C. S., Rowat, A. C. & Henry, M. D. (2020). Cancer Cells Resist Mechanical Destruction in Circulation via RhoA/Actomyosin-Dependent Mechano-Adaptation. Cell reports 30 (11) 3864-3874.e6. PMID: 32187555. DOI: 10.1016/j.celrep.2020.02.080.
- Feddersen, C. R., Schillo, J. L., Varzavand, A., Vaughn, H. R., Wadsworth, L. S., Voigt, A. P., Zhu, E. Y., Jennings, B. M., Mullen, S. A., Bobera, J., Riordan, J. D., Stipp, C. S. & Dupuy, A. J. (2019). Src-Dependent DBL Family Members Drive Resistance to Vemurafenib in Human Melanoma. Cancer research 79 (19) 5074-5087. PMID: 31416844. DOI: 10.1158/0008-5472.CAN-19-0244.
- Riordan, J. D., Feddersen, C. R., Tschida, B. R., Beckmann, P. J., Keng, V. W., Linden, M. A., Amin, K., Stipp, C. S., Largaespada, D. A. & Dupuy, A. J. (2018). Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma in mice. Hepatology 67 (3) 924-939. PMID: 28961327.
- Gomez-Contreras, P., Ramior-Diaz, J. M., Sierra, A., Stipp, C., Domann, F. E., Weigel, R. J. & Lal, G. (2017). Extracellular matrix 1 (ECM1) regulates the actin cytoskeletal architecture of aggressive breast cancer cells in part via S100A4 and Rho-family GTPases. Clinical & Experimental Metastasis 34 (1) 37-49. PMID: 27770373.
- Varzavand, A., Hacker, W., Ma, D., Gibson-Corley, K., Hawayek, M., Tayh, O. J., Brown, J. A., Henry, M. D. & Stipp, C. S. (2016). α3β1 Integrin Suppresses Prostate Cancer Metastasis via Regulation of the Hippo Pathway. Cancer Research 76 (22) 6577-6587. PMID: 27680681.
- Fullenkamp, C. A., Hall, S. L., Jaber, O. I., Pakalniskis, B. L., Savage, E. C., Savage, J. M., Ofori-Amanfo, G. K., Lambertz, A. M., Ivins, S. D., Stipp, C. S., Miller, B. J., Milhem, M. M. & Tanas, M. R. (2016). TAZ and YAP are frequently activated oncoproteins in sarcomas. Oncotarget 7 (21) 30094-30108. PMID: 27129148.
- Zevian, S. C., Johnson, J. L., Winterwood, N. E., Walters, K. S., Herndon, M. E., Henry, M. D. & Stipp, C. S. (2015). CD151 promotes α3β1 integrin-dependent organization of carcinoma cell junctions and restrains collective cell invasion. Cancer Biology & Therapy 16 (11) 1626-40. PMID: 26418968. DOI: 10.1080/15384047.2015.1095396.
- Gustafson-Wagner, E. & Stipp, C. S. (2013). The CD9/CD81 tetraspanin complex and tetraspanin CD151 regulate α3β1 integrindependent tumor cell behaviors by overlapping but distinct mechanisms. PLoS One 8 (4) e61834. DOI: 10.1371/journal.pone.0061834.