Michael E. Wright, PhD

Portrait
Associate Professor of Molecular Physiology and Biophysics

Contact Information

Primary Office: 5-630 BSB
51 Newton Road
Iowa City, IA 52242
319-384-1764

Lab: 5-611C BSB
51 Newton Road
Iowa City, IA 52242
319-384-1765

Education

BS, Biology, Minor: Chemistry, University of Nevada
PhD, Molecular and Cellular Biology, University of Washington

Fellow, Howard Hughes
Post Doctoral Fellow, University of Washington
Post Doctoral Fellow, United Negro College
Post Doctoral Fellow, Molecular Biotechnology, Department of Molecular Biotechnology and Institutes for Systems Biology

Education/Training Program Affiliations

Department of Molecular Physiology and Biophysics PhD, Medical Scientist Training Program

Research Summary

My laboratory utilizes quantitative mass spectrometry to study signal transduction pathways in normal and diseased cells. We are studying how perturbations in androgen receptor signaling impacts disease progression in human prostate cancer. Our long-term goals are to build quantitative models of androgen-regulated signaling pathways in prostate cancer. We will use these models to understand the evolution and progression of hormone-refractory prostate cancers. We anticipate our findings will define new biomarkers of diagnostic, prognostic, or therapeutic value to patients afflicted by life-threatening hormone-refractory prostate cancers.