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Peter Snyder, MD

Professor of Internal Medicine-Cardiovascular Medicine

Current Positions

  • Professor of Internal Medicine-Cardiovascular Medicine
  • Professor of Molecular Physiology and Biophysics
  • Associate Dean for Faculty Affairs and Development, University of Iowa Carver College of Medicine

Education

  • MD, University of Iowa College of Medicine, Iowa City, Iowa
  • Resident, Internal Medicine, University of Texas, Southwestern, Dallas, Texas
  • Fellow, Cardiovascular Medicine, University of Iowa Hospitals & Clinics, Iowa City, Iowa
  • Postdoctoral Research Fellow, Howard Hughes Medical Institute, University of Iowa, Iowa City, Iowa

Graduate Program Affiliations

Center, Program and Institute Affiliations

Research Interests

  • Dr. Snyder's clinical interest is general cardiology. His research interest is understanding function and regulation of the DEG/ENaC family of ion channels. Defects in those channels cause hypertension and contribute to the pathogenesis of cystic fibrosis.

Licenses & Certifications

  • Medical License, Iowa Board of Medicine
  • Certification, American Board of Internal Medicine
  • Certification, American Board if Internal Medicine, Cardiovascular Disease

Selected Publications

  • Polgreen, L. A., Carter, C. L., Polgreen, P. M., Snyder, P. M., Sewell, D. K., Bayman, E. O., Francis, S. L., Simmering, J. E., Parker, C. & Finkelstein, R. (2020). A pharmacist intervention for monitoring and treating hypertension using bidirectional texting: PharmText BP. (Vols. 106169). Contemp Clin Trials. PMID: 33038500.
  • Khataei, T., Harding, A. M., Janahmadi, M., El-Geneidy, M., Agha-Alinejad, H., Rajabi, H., Snyder, P. M., Sluka, K. A. & Benson, C. J. (2020). ASICs are required for immediate exercise-induced muscle pain and are downregulated in sensory neurons by exercise training. (Vols. 129). (1), pp. 17-26. J Appl Physiol (1985). PMID: 32463731.
  • Raikwar, N., Braverman, C., Snyder, P. M., Fenton, R. A., Meyerholz, D., Abboud, F. C. & Harwani, S. C. (2019). Renal denervation and CD161a immune ablation prevent cholinergic hypertension and renal sodium retention. (Vols. 317). pp. H517-H530. Am J Physiol Heart Circ Physiol. PMID: 31172810. PMCID: 6766722.
  • Butler, P. L., Staruschenko, A. & Snyder, P. M. (2015). Acetylation stimulates the epithelial sodium channel by reducing its ubiquitination and degradation. J Biol Chem 290 (20) 12497-503. PMCID: 4432271.
  • Collier, D. M., Tomkovicz, V. R., Peterson, Z. J., Benson, C. J. & Snyder, P. M. (2014). Intersubunit conformational changes mediate epithelial sodium channel gating. The Journal of general physiology 144 (4) 337-48. DOI: 10.1085/jgp.201411208. PMID: 25225551.
  • Ly, K., McIntosh, C. J., Biasio, W., Liu, Y., Ke, Y., Olson, D. R., Miller, J. H., Page, R., Snyder, P. M. & McDonald, F. J. (2013). Regulation of the delta and alpha epithelial sodium channel (ENaC) by ubiquitination and Nedd8. Journal of cellular physiology 228 (11) 2190-201. PMID: 23589227.
  • Zhou, R., Tomkovicz, V. R., Butler, P. L., Ochoa, L. A., Peterson, Z. J. & Snyder, P. M. (2013). Ubiquitin-specific peptidase 8 (USP8) regulates endosomal trafficking of the epithelial Na+ channel. J Biol Chem 288 (8) 5389-97. PMID: 23297398. PMCID: 3581384.
  • Kusama, N., Gautam, M., Harding, A. M., Snyder, P. M. & Benson, C. J. (2013). Acid-sensing ion channels (ASICs) are differentially modulated by anions dependent on their subunit composition. Am J Physiol Cell Physiol 304 (1) C89-101. PMID: 23135698. PMCID: 3543573.
  • Sierra, A., Zhu, Z., Sapay, N., Sharotri, V., Kline, C. F., Luczak, E. D., Subbotina, E., Sivaprasadarao, A., Snyder, P. M., Mohler, P. J., Anderson, M. E., Vivaudou, M., Zingman, L. V. & Hodgson-Zingman, D. M. (2013). Regulation of cardiac ATP-sensitive potassium channel surface expression by calcium/calmodulin-dependent protein kinase II. J Biol Chem 288 (3) 1568-81. PMID: 23223335. PMCID: 3548467.
  • Snyder, P. M. (2012). Intoxicated Na(+) channels. Focus on "ethanol stimulates epithelial sodium channels by elevating reactive oxygen species". Am J Physiol Cell Physiol 303 (11) C1125-6. PMID: 22992679. PMCID: 3530772.