Douglas R. Langbehn, MD, PhD

Portrait
Professor of Psychiatry
Professor of Biostatistics

Contact Information

Office: 1-290 Medical Education Building
Iowa City, IA 52242
319-384-4455

Education

BA, Biology, Drake University, Des Moines, IA
MD, University of Iowa College of Medicine, Iowa City, IA
MS, Preventative Medicine, University of Iowa, Iowa City, IA
MS, Preventative Medicine - Biometry, University of Iowa, Iowa City, IA
PhD, Preventative Medicine - Biometry, University of Iowa, Iowa City, IA

Resident, Psychiatry, University of Iowa Hospitals & Clinics
Fellow, NIMH Mental Health Biometry and Epidemiology Training Program, University of Iowa
Fellow, Psychiatry, University of Iowa Hospitals & Clinics

Licensure and Certifications

Psychiatry certification - American Board of Psychiatry & Neurology

Publications

Gregory, S., Crawford, H., Seunarine, K., Leavitt, B., Durr, A., Roos RAC,, Scahill, R. I., Tabrizi, S. J., Rees, G., Langbehn, D. & Orth, M. (2018). Natural biological variation of white matter microstructure is accentuated in Huntington's disease. Human brain mapping. PMID: 29682858.

Hensman Moss, D. J., Pardiñas, A. F., Langbehn, D., Lo, K., Leavitt, B. R., Roos, R., Durr, A., Mead, S., Holmans, P., Jones, L., Tabrizi, S. J. & REGISTRY and TRACK-HD investigators, (2017). Identification of genetic variants associated with Huntington’s disease progression. Lancet Neurology. PMID: 28642124.

Byrne, L. M., Rodrigues, F. B., Blennow, K., Durr, A., Leavitt, B. R., Roos, R. C., Scahill, R. I., Tabrizi, S. J., Zetterberg, H., Langbehn, D. & Wild, E. J. (2017). Huntington's disease: a retrospective cohort analysis. Lancet Neurol.

Hessman Moss, D. J., Flower, M. D., Lo, K. K., Miller, J. R., van Ommen, G. B., t' Hoen, P. A., Stone, T. C., Guinee, A., Langbehn, D. R., Jones, L., Plagnol, V., van Roon-Mom, W. M., Holmans, P. & Tabrizi, S. J. (2017). Huntington's disease blood and brain show a common gene expression pattern and share an immune signature with Alzheimer's disease. Scientific Reports. DOI: 10.1038/srep44849.

Long, J. D., Mills, J. A., Leavitt, B. R., Durr, A., ...,, Langbehn, D. R., et al, (2017). Survival end points for Huntington disease trials prior to a motor diagnosis. JAMA Neurology, 74(11), 1-9.

Coryell, W. H., Langbehn, D. R., Norris, A. W., Yao, J. R., Dindo, L. N. & Calarge, C. A. (2017). Polyunsaturated fatty acid composition and childhood adversity: Independent correlates of depressive symptom persistence. Psychiatry Res, 256, 305-311.

Gregory, S., Long, J. D., Kloppel, S., Razi, A., Scheller, E., Minkova, L., Papoutsi, M., Mills, J. A., Durr, A., Leavitt, B. R., Roos, R. A., Stout, J. C., Scahill, R. I., Langbehn, D. R., Tabrizi, S. J. & Rees, G. (2017). Operationalizing compensation over time in neurodegenerative disease. Brain, 140(4), 1158-1165. PMID: 28334888.

Orth, M., Gregory, S., Scahill, R. I., Mayer, I. S., Minkova, L., Klöppel, S., Seunarine, K. K., Boyd, L., Borowsky, B., Reilmann, R., Bernhard Landwehrmeyer, G., Leavitt, B. R., Roos, R. A., Durr, A., Rees, G., Rothwell, J. C., Langbehn, D. & Tabrizi, S. J. (2016). Natural variation in sensory-motor white matter organization influences manifestations of Huntington's disease. Hum Brain Mapp.

Long, J. D., Langbehn, D. R., Tabrizi, S. J., Landwehrmeyer, B. G., Paulsen, J. S., Warner, J. & Sampaio, C. (2016). Validation of a prognostic index for Huntington's disease. Mov Disord.

Keogh, R., Frost, C., Owen, G., Daniel, R. m., Langbehn, D. R., Leavitt, B., Durr, A., Roos, R. A., Landwehrmeyer, G. B., Reilmann, R., Borowsky, B., Stout, J., Craufurd, D. & Tabrizi, S. J. (2016). Medication Use in Early-HD Participants in Track-HD: an Investigation of its Effects on Clinical Performance. PLoS Curr, 8.

Beglinger, L. J., Adams, W. H., Fiedorowicz, J. G., Duff, K., Langbehn, D., Biglan, K., Caviness, J., Olsen, B. & Paulsen, J. S. (2015). Practice effects of neuropsychological tests and the UHDRS over short retest intervals in Huntington disease. Journal of Huntington’s Disease. PMID: 26444022.

Wild, E. J., Boggio, R., Langbehn, D., Robertson, N., Haider, S., Miller, J. R., Zetterberg, H., Leavitt, B., Kuhn, R., Tabrizi, S., Macdonald, D. & Weiss, A. (2015). Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients. The Journal of Clinical Investigation, 5(125), 1979-86.

Becanovic, K., Nørremølle, A., Neal, S. J., Kay, C., Collins, J. A., Arenillas, D., Lilja, T., Gaudenzi, G., Monoharan, S., Doty, C. N., Beck, J., Lahiri, N., Portales-Casamar, E., Warby, S. C., Connolly, C., De Souza, R. A., Tabrizi, S. J., Hermanson, O., Langbehn, D. R., Hayden, M. R., Wasserman, W. W. & Leavitt, B. R. (2015). A SNP in the HTT promoter alters NF-?B binding and is a bidirectional genetic modifier of Huntington disease. Nature Neuroscience. PMID: 25938884.

Beglinger, L. J., Adams, W. H., Duff, K., Langbehn, D., Fiedorowicz, J. G., Biglan, K., Caviness, J., Olson, B. & Paulsen, J. S. (2015). Practice effects of neuropsychological tests and the UHDRS over short retest intervals in Huntington disease. Journal of Huntington’s Disease, 4(3), 251-260. PMID: 26444022.

Johnson, E. B., Reese, E. M., Labuschangnel, I., Durr, A., Leavitt, B. R., Roos, R. A., Johnson, H., Hobbs, N. Z., Langbehn, D. R., Stout, J. C., Tabrizi, S. J., Scahill, R. I. & TRACK-HD investigators (2015). The impact of occipital lobe cortical thickness on cognitive task performance: An investigation in Huntington's Disease. Neuropsychologia. PMID: 26519555.

Jones, R., Stout, J. C., Labuschagne, I., Say, M., Justo, D., Coleman, A., Dumas, E. M., Hart, E., Owen, G., Durr, A., Leavitt, B. R., Roos, R., O'Reagan, A., Langbehn, D., Tabrizi, S. J. & Frost, C. (2014). The potential of composite cognitive scores for tracking progression in Huntington's disease. J Huntingtons Dis, 3(2), 197-207. PMID: 25062862.

Beglinger, L. J., Adams, W. H., Langbehn, D., Fiedorowicz, J. G., Caviness, J., Biglan, K., Olson, B. & Paulsen, J. S. (2014). Does Interval Between Screening and Baseline Matter in HD Cognitive Clinical Trials?. Journal of Huntington's Disease, 3(2). PMID: 25062857.

Ross, C. A., Aylward, E. H., Wild, E. J., Langbehn, D. R., Long, J. D., Warner, J. H., Scahill, R. I., Leavitt, B. R., Stout, J. C., Paulsen, J. S., Reilmann, R., Unschuld, P. G., Wexler, A., Margolis, R. L. & Tabrizi, S. J. (2014). Huntington disease: natural history, biomarkers and prospects for therapeutics. Nat Rev Neurol. PMID: 24614516.

Langbehn, D. R. (2014). Criteria for success in safety and tolerability trials. The Lancet Neurology. DOI: 10.1016/S1474-4422(14)70265-0.

Munafo, M., Noble, S., Browne, W. J., Brunner, D., Button, K., Ferreira, J., Holmans, P., Langbehn, D., Lewis, G., Lindquist, M., Tilling, D., Wagenmakers, E. & Blumenstein, R. (2014). Scientific rigor and the art of motorcycle maintenance. Nature Biotechnology, 32, 871-873. PMID: 25203032.

Tabrizi, S. J., Scahill, R. I., Owen, G., Durr, A., Leavitt, B. R., Roos, R. A., Borowsky, B., Landwehrmeyer, B., Frost, C., Johnson, H. J., Craufurd, D., Reilmann, R., Stout, J. C., Langbehn, D. (2013). "Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data". The Lancet Neurology.

Scahill, R. I., Hobbs, N. Z., Say, M. J., Bechtel, N., Henley, S. M., Hyare, H., Langbehn, D. R., Jones, R., Leavitt, B. R., Roos, R. A., Durr, A., Johnson, H., Lehéricy, S., Craufurd, D., Kennard, C., Hicks, S. L., Stout, J. C., Reilmann, R. & Tabrizi, S. J. (2013). Clinical impairment in premanifest and early Huntington's disease is associated with regionally specific atrophy. Human brain mapping, 34(3), 519-29. PMID: 22102212.

Crawford, H. E., Hobbs, N. Z., Keough, R., Langbehn, D. R., Frost, C., Johnson, H. J., Landwehrmeyer, B., Reilmann, R., Crauford, D., Stout, J. C., Durr, A., Leavitt, B. R., Roos, R. A., Tabrizi, S. J. & Scahill, R. I. (2013). Corpus callosal atrophy in premanifest and early Huntington's disease. Journal of Huntington's Disease, 2(4), 517-536. PMID: 25062736.

Divino, V., Dekoven, M., Warner, J. H., Giuliano, J., Anderson, K. E., Langbehn, D. & Lee, W. C. (2013). The direct medical costs of Huntington's disease by stage. A retrospective commercial and Medicaid claims data analysis. (Vols. 16). (8), pp. 1043-1050. J Med Econ. PMID: 23789925.

Rowe, K. C., Paulsen, J. S., Langbehn, D. R., Wang, C., Mills, J., Beglinger, L. J., Smith, M. M., Epping, E. A., Fiedorowicz, J. G., Duff, K., Ruggle, A. & Moser, D. J. (2012). Patterns of serotonergic antidepressant usage in prodromal Huntington disease. Psychiatry research, 196(2-3), 309-14. PMID: 22397915.

Stout, J. C., Jones, R., Labuschagne, I., O'Regan, A. M., Say, M. J., Dumas, E. M., Queller, S., Justo, D., Santos, R. D., Coleman, A., Hart, E. P., Dürr, A., Leavitt, B. R., Roos, R. A., Langbehn, D. R., Tabrizi, S. J. & Frost, C. (2012). Evaluation of longitudinal 12 and 24 month cognitive outcomes in premanifest and early Huntington's disease. Journal of neurology, neurosurgery, and psychiatry, 83(7), 687-94. PMID: 22566599.

Chen, T., Wang, Y., Ma, Y., Marder, K. & Langbehn, D. R. (2012). Predicting Disease Onset from Mutation Status Using Proband and Relative Data with Applications to Huntington's Disease. Journal of probability and statistics, 2012. PMID: 23476655.

Tabrizi, S. J., Reilmann, R., Roos, R. A., Durr, A., Leavitt, B., Owen, G., Jones, R., Johnson, H., Craufurd, D., Hicks, S. L., Kennard, C., Landwehrmeyer, B., Stout, J. C., Borowsky, B., Scahill, R. I., Frost, C. & Langbehn, D. R. (2012). Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data. Lancet neurology, 11(1), 42-53. PMID: 22137354.

O'Rourke, J. J., Beglinger, L. J., Smith, M. M., Mills, J., Moser, D. J., Rowe, K. C., Langbehn, D. R., Duff, K., Stout, J. C., Harrington, D. L., Carlozzi, N. & Paulsen, J. S. (2011). The Trail Making Test in prodromal Huntington disease: contributions of disease progression to test performance. Journal of clinical and experimental neuropsychology, 33(5), 567-79. PMID: 21302170.

van den Bogaard, S. J., Dumas, E. M., Acharya, T. P., Johnson, H., Langbehn, D. R., Scahill, R. I., Tabrizi, S. J., van Buchem, M. A., van der Grond, J. & Roos, R. A. (2011). Early atrophy of pallidum and accumbens nucleus in Huntington's disease. Journal of neurology, 258(3), 412-20. PMID: 20936300.

Fiedorowicz, J. G., Mills, J. A., Ruggle, A., Langbehn, D. & Paulsen, J. S. (2011). Suicidal behavior in prodromal Huntington disease. Neuro-degenerative diseases, 8(6), 483-90. PMID: 21659725.

Nopoulos, P. C., Aylward, E. H., Ross, C. A., Mills, J. A., Langbehn, D. R., Johnson, H. J., Magnotta, V. A., Pierson, R. K., Beglinger, L. J., Nance, M. A., Barker, R. A. & Paulsen, J. S. (2011). Smaller intracranial volume in prodromal Huntington's disease: evidence for abnormal neurodevelopment. Brain : a journal of neurology, 134(Pt 1), 137-42. PMID: 20923788.

Stout, J. C., Paulsen, J. S., Queller, S., Solomon, A. C., Whitlock, K. B., Campbell, J. C., Carlozzi, N., Duff, K., Beglinger, L. J., Langbehn, D. R., Johnson, S. A., Biglan, K. M. & Aylward, E. H. (2011). Neurocognitive signs in prodromal Huntington disease. Neuropsychology, 25(1), 1-14. PMID: 20919768.

Aylward, E. H., Nopoulos, P. C., Ross, C. A., Langbehn, D. R., Pierson, R. K., Mills, J. A., Johnson, H. J., Magnotta, V. A., Juhl, A. R. & Paulsen, J. S. (2011). Longitudinal change in regional brain volumes in prodromal Huntington disease. Journal of neurology, neurosurgery, and psychiatry, 82(4), 405-10. PMID: 20884680.

Carlozzi, N. E., Stout, J. C., Mills, J. A., Duff, K., Beglinger, L. J., Aylward, E. H., Whitlock, K. B., Solomon, A. C., Queller, S., Langbehn, D. R., Johnson, S. A. & Paulsen, J. S. (2011). Estimating premorbid IQ in the prodromal phase of a neurodegenerative disease. The Clinical neuropsychologist, 25(5), 757-77. PMID: 21660882.

Tabrizi, S. J., Scahill, R. I., Durr, A., Roos, R. A., Leavitt, B. R., Jones, R., Landwehrmeyer, G. B., Fox, N. C., Johnson, H., Hicks, S. L., Kennard, C., Craufurd, D., Frost, C., Langbehn, D. R., Reilmann, R. & Stout, J. C. (2011). Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis. Lancet neurology, 10(1), 31-42. PMID: 21130037.

Noyes, R., Kukoyi, O. A., Longley, S. L., Langbehn, D. R. & Stuart, S. P. (2011). Effects of continuity of care and patient dispositional factors on the physician-patient relationship. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 23(3), 180-5. PMID: 21808749.

Duff, K., Paulsen, J. S., Beglinger, L. J., Langbehn, D. R., Wang, C., Stout, J. C., Ross, C. A., Aylward, E., Carlozzi, N. E. & Queller, S. (2010). "Frontal" behaviors before the diagnosis of Huntington's disease and their relationship to markers of disease progression: evidence of early lack of awareness. The Journal of neuropsychiatry and clinical neurosciences, 22(2), 196-207. PMID: 20463114.

Paulsen, J. S., Nopoulos, P. C., Aylward, E., Ross, C. A., Johnson, H., Magnotta, V. A., Juhl, A., Pierson, R. K., Mills, J., Langbehn, D. & Nance, M. (2010). Striatal and white matter predictors of estimated diagnosis for Huntington disease. Brain research bulletin, 82(4-Mar), 201-7. PMID: 20385209.

Zhang, J., Peng, Q., Li, Q., Jahanshad, N., Hou, Z., Jiang, M., Masuda, N., Langbehn, D. R., Miller, M. I., Mori, S., Ross, C. A. & Duan, W. (2010). Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images. NeuroImage, 49(3), 2340-51. PMID: 19850133.

Rowe, K. C., Paulsen, J. S., Langbehn, D. R., Duff, K., Beglinger, L. J., Wang, C., O'Rourke, J. J., Stout, J. C. & Moser, D. J. (2010). Self-paced timing detects and tracks change in prodromal Huntington disease. Neuropsychology, 24(4), 435-42. PMID: 20604618.

Noyes, R., Longley, S. L., Langbehn, D. R., Stuart, S. P. & Kukoyi, O. A. (2010). Hypochondriacal symptoms associated with a less therapeutic physician-patient relationship. Psychiatry, 73(1), 57-69. PMID: 20235618.

Duff, K., Paulsen, J., Mills, J., Beglinger, L. J., Moser, D. J., Smith, M. M., Langbehn, D., Stout, J., Queller, S. & Harrington, D. L. (2010). Mild cognitive impairment in prediagnosed Huntington disease. Neurology, 75(6), 500-7. PMID: 20610833.

Bechtel, N., Scahill, R. I., Rosas, H. D., Acharya, T., van den Bogaard, S. J., Jauffret, C., Say, M. J., Sturrock, A., Johnson, H., Onorato, C. E., Salat, D. H., Durr, A., Leavitt, B. R., Roos, R. A., Landwehrmeyer, G. B., Langbehn, D. R., Stout, J. C., Tabrizi, S. J. & Reilmann, R. (2010). Tapping linked to function and structure in premanifest and symptomatic Huntington disease. Neurology, 75(24), 2150-60. PMID: 21068430.

Langbehn, D. R., Hayden, M. R. & Paulsen, J. S. (2010). CAG-repeat length and the age of onset in Huntington disease (HD): a review and validation study of statistical approaches. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 153B(2), 397-408. PMID: 19548255.

Nopoulos, P. C., Aylward, E. H., Ross, C. A., Johnson, H. J., Magnotta, V. A., Juhl, A. R., Pierson, R. K., Mills, J., Langbehn, D. R. & Paulsen, J. S. (2010). Cerebral cortex structure in prodromal Huntington disease. Neurobiology of disease, 40(3), 544-54. PMID: 20688164.

Beglinger, L. J., O'Rourke, J. J., Wang, C., Langbehn, D. R., Duff, K. & Paulsen, J. S. (2010). Earliest functional declines in Huntington disease. Psychiatry research, 178(2), 414-8. PMID: 20471695.

Paulsen, J. S., Wang, C., Duff, K., Barker, R., Nance, M., Beglinger, L., Moser, D., Williams, J. K., Simpson, S., Langbehn, D. & van Kammen, D. P. (2010). Challenges assessing clinical endpoints in early Huntington disease. Movement disorders : official journal of the Movement Disorder Society, 25(15), 2595-603. PMID: 20623772.

Duff, K., Langbehn, D. R., Schoenberg, M. R., Moser, D. J., Baade, L. E., Mold, J. W., Scott, J. G. & Adams, R. L. (2009). Normative data on and psychometric properties of Verbal and Visual Indexes of the RBANS in older adults. The Clinical neuropsychologist, 23(1), 39-50. PMID: 18609313.

Magnotta, V. A., Kim, J., Koscik, T., Beglinger, L. J., Espinso, D., Langbehn, D., Nopoulos, P. & Paulsen, J. S. (2009). Diffusion Tensor Imaging in Preclinical Huntington's Disease. Brain imaging and behavior, 3(1), 77-84. PMID: 21415933.

Biglan, K. M., Ross, C. A., Langbehn, D. R., Aylward, E. H., Stout, J. C., Queller, S., Carlozzi, N. E., Duff, K., Beglinger, L. J. & Paulsen, J. S. (2009). Motor abnormalities in premanifest persons with Huntington's disease: the PREDICT-HD study. Movement disorders : official journal of the Movement Disorder Society, 24(12), 1763-72. PMID: 19562761.

Coryell, M. W., Wunsch, A. M., Haenfler, J. M., Allen, J. E., Schnizler, M., Ziemann, A. E., Cook, M. N., Dunning, J. P., Price, M. P., Rainier, J. D., Liu, Z., Light, A. R., Langbehn, D. R. & Wemmie, J. A. (2009). Acid-sensing ion channel-1a in the amygdala, a novel therapeutic target in depression-related behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience, 29(17), 5381-8. PMID: 19403806.

Tabrizi, S. J., Langbehn, D. R., Leavitt, B. R., Roos, R. A., Durr, A., Craufurd, D., Kennard, C., Hicks, S. L., Fox, N. C., Scahill, R. I., Borowsky, B., Tobin, A. J., Rosas, H. D., Johnson, H., Reilmann, R., Landwehrmeyer, B. & Stout, J. C. (2009). Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data. Lancet neurology, 8(9), 791-801. PMID: 19646924.

Beglinger, L. J., Adams, W. H., Paulson, H., Fiedorowicz, J. G., Langbehn, D. R., Duff, K., Leserman, A. & Paulsen, J. S. (2009). Randomized controlled trial of atomoxetine for cognitive dysfunction in early Huntington disease. Journal of clinical psychopharmacology, 29(5), 484-7. PMID: 19745649.

Carlozzi, N. E., Stout, J. C., Whitlock, K. B., Queller, S., Aylward, E. H., Langbehn, D. R., Duff, K., Beglinger, L. J., Paulsen, J. & The Predict-HD HSG, I. (2008). Estimating premorbid IQ in the prodromal phase of a neurodegenerative disease in the Predict-HD cohort. 35th Annual International Neuropsychological Society meeting.

Whitlock, K. B., Stout, J. C., Queller, S., Carlozzi, N. E., Langbehn, D. R., Paulsen, J. S. & The Predict-HD HSG, I. (2008). Individual and combined item analyses can shorten test length for the University of Pennsylvania Smell ID Test. Featured poster at 35th Annual International Neuropsychological Society meeting.

Beglinger, L. J., Paulsen, J. S., Watson, D. B., Wang, C., Duff, K., Langbehn, D. R., Moser, D. J., Paulson, H. L., Aylward, E. H., Carlozzi, N. E., Queller, S. & Stout, J. C. (2008). Obsessive and compulsive symptoms in prediagnosed Huntington's disease. The Journal of clinical psychiatry, 69(11), 1758-65. PMID: 19012814.

Paulsen, J. S., Langbehn, D. R., Stout, J. C., Aylward, E., Ross, C. A., Nance, M., Guttman, M., Johnson, S., MacDonald, M., Beglinger, L. J., Duff, K., Kayson, E., Biglan, K., Shoulson, I., Oakes, D. & Hayden, M. (2008). Detection of Huntington's disease decades before diagnosis: the Predict-HD study. Journal of neurology, neurosurgery, and psychiatry, 79(8), 874-80. PMID: 18096682.

Spinks, R., Caspers, K., Langbehn, D., Yucuis, R., McKirgan, L. W., Arndt, S., Pfalzgraf, C. J. & Cadoret, R. (2007). Co-morbid health conditions at mid-life in the Iowa adoptees. Addictive behaviors, 32(5), 991-1002. PMID: 16914269.

Stout, J. C., Queller, S., Langbehn, D., Johnson, S. A., Carlozzi, N. E., Duff, K., Beglinger, L. J. & Paulsen, J. S. (2007). Two-Year longitudinal sensitivity of cognitive measures in pre-diagnosis Huntington's disease in the Predict-HD cohort. Poster session presented at the 18th Annual Meeting of the American Neuropsychiatric Association.

Johnson, S. A., Stout, J. C., Solomon, A. C., Langbehn, D. R., Aylward, E. H., Cruce, C. B., Ross, C. A., Nance, M., Kayson, E., Julian-Baros, E., Hayden, M. R., Kieburtz, K., Guttman, M., Oakes, D., Shoulson, I., Beglinger, L., Duff, K., Penziner, E. & Paulsen, J. S. (2007). Beyond disgust: impaired recognition of negative emotions prior to diagnosis in Huntington's disease. Brain : a journal of neurology, 130(Pt 7), 1732-44. PMID: 17584778.

Boes, A. D., Murko, V., Wood, J. L., Langbehn, D. R., Canady, J., Richman, L. & Nopoulos, P. (2007). Social function in boys with cleft lip and palate: relationship to ventral frontal cortex morphology. Behavioural brain research, 181(2), 224-31. PMID: 17537526.

Nopoulos, P., Langbehn, D. R., Canady, J., Magnotta, V. & Richman, L. (2007). Abnormal brain structure in children with isolated clefts of the lip or palate. Archives of pediatrics & adolescent medicine, 161(8), 753-8. PMID: 17679656.

Langbehn, D. R., Paulsen, J. S. (2007). Predictors of diagnosis in Huntington disease. Neurology, 68(20), 1710-7. PMID: 17502553.

Solomon, A. C., Stout, J. C., Johnson, S. A., Langbehn, D. R., Aylward, E. H., Brandt, J., Ross, C. A., Beglinger, L., Hayden, M. R., Kieburtz, K., Kayson, E., Julian-Baros, E., Duff, K., Guttman, M., Nance, M., Oakes, D., Shoulson, I., Penziner, E. & Paulsen, J. S. (2007). Verbal episodic memory declines prior to diagnosis in Huntington's disease. Neuropsychologia, 45(8), 1767-76. PMID: 17303196.

Langbehn, D. (2007). Room for Improved Standardization of the HD Motor Exam Scores and diangositc Confidence Ratings: Evidence form the Predict-HD Study. Presented as a subtopic in program listing: "Reilmann R. Motor Assessment: Rating Scales, Rater Training and Quantitative Testing".

Stout, J. C., Queller, S., Langbehn, D., Johnson, S. A., Carlozzi, N. E., Miura, T. k., Soloman, A. C., Cruce, C. B., Beglinger, L., Duff, K., Aylward, E. H. & Paulsen, J. S. (2007). Detecting cognitive changes in pre-diagnosis HD in the Predict-HD study. Poster session presented at the 35th Annual International Neuropsychological Society meeting.

Carlozzi, N. E., Stout, J. C., Queller, S., Whitlock, K. B., Langbehn, D. R., Beglinger, L., Duff, K., Ross, A., Paulsen, J. & The Predict-HD HSG, I. (2007). Cross-sectional neurocognitive measurement of pre-HD individuals in PREDICT-HD. Poster presentation at the 3rd World Congress on Huntington's Disease.

Carlozzi, N. E., Stout, J. C., Queller, S., Soloman, A., Duff, K., Beglinger, L., Langbehn, D. R. & Paulsen, J. S. (2007). Assessment of intellectual functioning in pre-diagnostic Huntington's disease. Poster session presented at the 35th Annual International Neuropsychological Society meeting.

Duff, K., Paulsen, J. S., Beglinger, L. J., Langbehn, D. R. & Stout, J. C. (2007). Psychiatric symptoms in Huntington's disease before diagnosis: the predict-HD study. Biological psychiatry, 62(12), 1341-6. PMID: 17481592.

Langbehn, D., Paulsen, J. S. & The Predict-HD HSG, I. (2007). Prospective Validation of CAG_Based Age of Diagnosis in Huntington's Disease. 3rd World Congress on Huntington's Disease.

Stout, J. C., Queller, S., Whitlock, K. B., Carlozzi, N. E., Langbehn, D. R., Paulsen, J. S. & The Predict-HD HSG, I. (2007). Controlling for individual differences in neurocognitive markers in pre-diagnosed HD in the Predict-HD cohort. Poster session accepted at the Annual Meeting of the Huntington Study Group.

Stout, J. C., Queller, S., Whitlock, K. B., Carlozzi, N. E., Langbehn, D. R., Paulsen, J. S. & The Predict-HD HSG, I. (2007). Controlling for Individual Differences in Neurocognitive Markers in Pre-Diagnosed HD in the Predict-HD Cohort. Inaugural HD Clinical Research Symposium.

Stout, J. C., Carlozzi, N. E., Queller, S., Whitlock, K. B., Johnson, S. A., Langbehn, D. R., Beglinger, L. J., Duff, K., Paulsen, J. & The Predict-HD HSG, I. (2007). Candidates for Neurocognitive Markers in Pre-HD: Longitudinal Assessment from the Predict-HD Cohort. Inaugural HD Clinical Research Symposium.

Duff, K., Beglinger, L. J., Schultz, S. K., Moser, D. J., McCaffrey, R. J., Haase, R. F., Westervelt, H. J., Langbehn, D. R. & Paulsen, J. S. (2007). Practice effects in the prediction of long-term cognitive outcome in three patient samples: a novel prognostic index. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, 22(1), 15-24. PMID: 17142007.

Caspers, K., Yucuis, R., Troutman, B., Arndt, S. & Langbehn, D. (2007). A sibling adoption study of adult attachment: the influence of shared environment on attachment states of mind. Attachment & human development, 9(4), 375-91. PMID: 18049934.

Whitlock, K. B., Stout, J. C., Queller, S., Langbehn, D. R., Carlozzi, N. E., Paulsen, J. S. & The Predict-HD HSG, I. (2007). Item Reduction of the University of Pennsylvania Smell ID Test: Preparation for Clinical Trials in pre-HD using the Predict HD Cohort. Inaugural HD Clinical Research Symposium.

Johnson, S. A., Stout, J. C., Queller, S., Whitlock, K. B., Langbehn, D. R., Aylward, E., Paulsen, J. S. & The Predict-HD HSG, I. (2007). Longitudinal Decline in Negative Emotion Recognition Prior to Diagnosis in Huntington's Disease. Inaugural HD Clinical Research Symposium.

Langbehn, D. (2007). Overview and Examples of Accomplishments (With Some Comments Generalizable to Clinical Neuro-psychiatric Research). Psychiatry research Rounds.

Ross, C. A., Biglan, K., Stout, J. C., Queller, S., Carlozzi, N. E., Duff, K., Beglinger, L. J., Langbehn, D., Paulsen, J. & The Predict-HD HSG, I. (2007). The UHDRS Motor Exam and Speeded Tapping in the Predict-HD Cohort Abstract. Accepted for Platform Presentation at the 21st Annual Symposium on the Etiology, Pathogenesis and Treatment of Parkinson's Disease and Other Movement Disorders.

Duff, K., Paulsen, J. S., Beglinger, L. J., Stout, J. C., Langbehn, D. R., Wang, C., Queller, S., Carlozzi, N. E. & The Predict-HD HSG, I. (2007). The "depression phenotype" in pre-diagnosed Huntington's disease. Abstract accepted for Platform Presentation at the 21st Annual Symposium on the Etiology, Pathogenesis and Treatment of Parkinson's Disease and Other Movement Disorders.

Carlozzi, N. E., Stout, J. C., Langbehn, D., Soloman, A., Queller, S., Duff, K., Beglinger, L. J. & Paulsen, J. S. (2007). Factor analysis of neuropsychological tasks in pre-diagnosed Huntington's disease. Poster session accepted at the 27th Annual Conference of the National Academy of Neuropsychology.

Swain, S. N., Carlozzi, N. E., Stout, J. C., Queller, S., Soloman, A. C., Beglinger, L., Duff, K., Miura, T. K., Langbehn, D. R. & Paulsen, J. S. (2007). Sensitivity to disease-related changes. Poster session accepted at the 27th Annual Conference of the National Academy of Neuropsychology.

Beglinger, L. J., Langbehn, D. R., Duff, K., Stierman, L., Black, D. W., Nehl, C., Anderson, K., Penziner, E. & Paulsen, J. S. (2007). Probability of obsessive and compulsive symptoms in Huntington's disease. Biological psychiatry, 61(3), 415-8. PMID: 16839521.

Langbehn, D. R., Paulsen, J. S., Ross, C. A., Biglan, K., Landwehrmeyer, B. & The Predict-HD HSG, I. (2007). Poster. Published in the program booklet of the Inaugural Huntington Disease Clinical Research Symposium.

Cadoret, R. J., Langbehn, D., Troughton, E. & Yucuis, R. Paths of genetic and environmental influence: The routes connecting personality disorders with substance use disorders.

Nopoulos, P., Paulsen, J. S., Beglinger, L. J., Johnson, S. A., Magnotta, V., Pierson, R., Langbehn, D. R. & The Predict-HD HSG, I. (2007). Abnormal Structure of Cerebral White and Cortical Gray Matter in Preclinical Huntington's Disease. pp. 20. Published in the program booklet of the Inaugural Huntington Disease Clinical Research Symposium.

Biglan, K. M., Ross, C. A., Langbehn, D., Aylward, E., Stout, J. C., Queller, S., Carlozzi, N., Duff, K., Beglinger, L., Paulsen, J. S. & The Predict-HD Investigators, H. (2007). Subtle Motor Abnormalities in Pre-Manifest HD Are Associated with Gene Status, Probability of Disease Onset, and Striatal Atrophy. Published in the program booklet of the Inaugural Huntington Disease Clinical Research Symposium 2007.

Paulsen, J. S., Langbehn, D. R., Wang, C., Duff, K., Beglinger, L. J., Carlozzi, N. E., Queller, S., Stout, J. C. & The Predict-HD HSG, I. (2007). Cognitive Predictors of HD Diagnosis in PREDICT-HD: A Prospective Study of Cognition in Phenoconversion. pp. 86. Published in the program booklet of World Congress on Huntington's Disease.

Beglinger, L. J., Paulsen, J. S., Duff, K., Wang, C., Langbehn, D. R., Watson, D., Stout, J. C., Carlozzi, N. E., Queller, S. & The Predict-HD HSG, I. (2007). Obsessive and Compulsive Symptoms in Pre-Diagnosed Huntington's Disease. pp. 108. Published in the program booklet of World Congress on Huntington's Disease 2007.

Duff, K., Paulsen, J. S., Beglinger, L. J., Stout, J. C., Carlozzi, N. E., Queller, S., Langbehn, D. R., Wang, C. & The Predict-HD HSG, I. (2007). Abstract. pp. 106. Published in the program booklet of World Congress on Huntington's Disease.

Stout, J. C., Carlozzi, N. E., Queller, S., Whitlock, K. B., Langbehn, D. R., Duff, K., Beglinger, L. J., Ross, A., Paulsen, J. & The Predict-HD HSG, I. (2007). Longitudinal Assessment of Pre-HD From the PREDCIT-HD COHORT: Preparation for Clinical Trials. pp. 63. Published in the program booklet of World Congress on Huntington's Disease.

Stout, J. C., Queller, S., Langbehn, D., Johnson, S. A., Carlozzi, N. E., Miura, T. k., Soloman, A. C., Cruce, C. B., Beglinger, L., Duff, K., Aylward, E. H. & Paulsen, J. S. (2006). Detecting cognitive changes in pre-diagnosis HD in the Predict-HD study. Abstract submitted to International Neuropsycholocial Society.

Soloman, A. C., Johnson, S. A., Stout, J. C., Paulsen, J. S., Duff, K., Langbehn, D. R. & The Predict-HD HSG, I. (2006). Movement initiation, execution and planning in pre-clinical Huntington's disease. Submitted for presentation at the meeting of the International Neuropsychological Society.

Noyes, R., Stuart, S., Watson, D. B. & Langbehn, D. R. (2006). Distinguishing between hypochondriasis and somatization disorder: a review of the existing literature. Psychotherapy and psychosomatics, 75(5), 270-81. PMID: 16899963.

Carlozzi, N. E., Stout, J. C., Queller, S., Soloman, A., Duff, K., Beglinger, L., Langbehn, D. R. & Paulsen, J. S. (2006). Assessment of intellectual functioning in pre-diagnostic Huntington's disease. Abstract submitted to International Neuropsychological Society.

Stout, J. C., Queller, S., Johnson, S. A., Ross, C., Langbehn, D. R. & Paulsen, J. S. (2006). Cognitive, motor and psychomotor function in pre-diagnostic carriers of the Huntington's disease CAG-expansion. Talk presented at Society of Neuroscience 36th Annual Meeting.

Duff, K., Langbehn, D. R., Schoenberg, M. R., Moser, D. J., Baade, L. E., Mold, J., Scott, J. G. & Adams, R. L. (2006). Examining the repeatable battery for the assessment of neuropsychological status: factor analytic studies in an elderly sample. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 14(11), 976-9. PMID: 17068320.

Paulsen, J. S., Hayden, M., Stout, J. C., Langbehn, D. R., Aylward, E., Ross, C. A., Guttman, M., Nance, M., Kieburtz, K., Oakes, D., Shoulson, I., Kayson, E., Johnson, S. & Penziner, E. (2006). Preparing for preventive clinical trials: the Predict-HD study. Archives of neurology, 63(6), 883-90. PMID: 16769871.

Carlozzi, N. E., Stout, J. C., Queller, S., Soloman, A., Duff, K., Beglinger, L., Aylward, E., Langbehn, D. & Paulsen, J. (2006). Relationship between markers of disease progression and intellectual functioning in pre-diagnostic Huntington's disease. Poster session presented at the Annual Meeting of the Huntington Study Group.

Langbehn, D. R., Philibert, R., Caspers, K. M., Yucuis, R. & Cadoret, R. J. (2006). Association of a D2S2944 allele with depression specifically among those with substance abuse or antisocial personality. Drug and alcohol dependence, 83(1), 33-41. PMID: 16289859.

Beglinger, L. J., Duff, K., Van Der Heiden, S., Parrott, K., Langbehn, D. & Gingrich, R. (2006). Incidence of delirium and associated mortality in hematopoietic stem cell transplantation patients. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 12(9), 928-35. PMID: 16920558.

Soloman, A. C., Stout, J. C., Johnson, S. A., Aylward, E., Langbehn, D. R., Duff, K., Brandt, J., Paulsen, J. S. & The Predict-HD HSG, I. (2005). Learning and Memory Performances are Associated with DNA-based Estimates of Onset and Striatal Volume in Presymptomatic HD. Annual Meeting of the International Neuropsychological Society.

Johnson, S. A., Lutring, J. D., Stout, J. C., Ross, C., Aylward, E. H., Langbehn, D. R., Paulsen, J. S. & Predict-HD/HSG, I. (2005). Motor, cognitive, and psychomotor symptoms in individuals at-risk for Huntington's Disease. Annual Meeting of the International Neuropsychological Society.

Ross, C. A., Biglan, E. M., Aylward, E., Stout, J. C., Kayson, E., Hayden, M., Shoulson, I., Oakes, D., Ahuja, A., Langbehn, D. R., Paulsen, J. S. & The Predict-HD Investigators of the HSG (2005). MRI and Cognitive characteristics correlate with predicted years to disease onset in preclinical HD: The Predict-HD Study. Movement Disorders Meeting.

Hoth, K. F., Paulsen, J. S., Beglinger, L. J., Aylward, E., Lagbehn, D., Nehl, C. & Stout, J. C. (2005). Awareness of Executive Dysfunction in Presymptomatic Huntington's Disease is Associated with MRI and Psychiatric Measures.

Cadoret, R. J., Caspers, K. & Langbehn, D. (2005). Genetic and Environmental Factors in Comorbidity of Alcohol Abuse/dependency Between Illicit Drug Abuse/dependency, Conduct Disorder and ADHD. Poster presented at the Guze Symposium for Alcoholism Research.

Spinks, R., Caspers, K., Langbehn, D. & Cadoret, R. J. (2005). Co-Morbid Health Conditions At Mid-Life in The Iowa Adoptees. Poster presented at the Guze Symposium for Alcoholism Research.

Johnson, S. A., Soloman, A. C., Stout, J. C., Cruce, C., Aylward, E. H., Langbehn, D. R., Paulsen, J. S. & Predict-HD HSG, I. (2005). Recognition of facial expressions in the Predict-HD cohort at baseline. Presented at the meeting of the Huntington Study Group.

Soloman, A. C., Johnson, S. A., Stout, J. C., Paulsen, J. S., Duff, K., Langbehn, D. R. & The Predict-HD HSG, I. (2005). Motor function in presymptomatic Huntington's disease: Evidence from a sequential button pressing task. Presented at the meeting of the Huntington Study Group.

Noyes, R., Carney, C. P., Hillis, S. L., Jones, L. E. & Langbehn, D. R. (2005). Prevalence and correlates of illness worry in the general population. Psychosomatics, 46(6), 529-39. PMID: 16288132.

Caspers, K., Cadoret, R. J., Langbehn, D., Spinks, R. & Yucuis, R. (2005). Co-Morbidity of Attachment Insecurity and Adult Psychopathology: Implications for Treatment. Poster presented at the Guze Symposium for Alcoholism Research.

Johnson, S. A., Soloman, A. C., Stout, J. C., Ross, C., Aylward, E. H., Langbehn, D. R., Paulsen, J. S. & Predict-HD HSG, I. (2005). Associations of motor, cognitive and psychomotor symptoms in the Predict-HD cohort at baseline. Presented at the meeting of the Huntington Study Group.

Caspers, K. M., Cadoret, R. J., Langbehn, D., Yucuis, R. & Troutman, B. (2005). Contributions of attachment style and perceived social support to lifetime use of illicit substances. Addictive behaviors, 30(5), 1007-11. PMID: 15893096.

Beglinger, L. J., Nopoulos, P. C., Jorge, R. E., Langbehn, D. R., Mikos, A. E., Moser, D. J., Duff, K., Robinson, R. G. & Paulsen, J. S. (2005). White matter volume and cognitive dysfunction in early Huntington's disease. Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology, 18(2), 102-7. PMID: 15970729.

Soloman, A. C., Queller, S., Johnson, S. A., Stout, J. C., Ross, C. A., Aylward, E., Langbehn, D. R., Paulsen, J. S. & The Predict-HD HSG, I. (2005). The serial reaction time task in individuals at-risk for Huntington's disease. Presented at the meeting of the Huntington Study Group.

Johnson, S. A., Stout, J. C., Langbehn, D., Coneybeare, R., Paulsen, J. S. & the Huntington Study, G. (2004). Recognition of static and dynamic facial expressions in the Predict-HD cohort at baseline. pp. 71. Presented at the 32nd Annual Meeting of the International Neuropsychological Society.

Langbehn, D., Brinkman, R. R., Falush, D., Paulsen, J. S., Hayden, M. R. & International Huntington, D. (2004). International Huntington Disease. Estimated prognosis and cross-sectional analysis of the baseline Predict Data. pp. 122. Presented at the 32nd Annual Meeting of the International Neuropsychological Society.

Duff, K., Langbehn, D., Nehl, D., Beglinger, L. & Paulsen, J. S. (2004). Presymptomatic symptoms in pre-symptomatic, gene positive Huntington Disease: Preliminary results from the Predict-HD study. Presented at the 15th Annual Meeting of the American Neuropsychiatric Association.

Noyes, R., Carney, C. P. & Langbehn, D. R. (2004). Specific phobia of illness: search for a new subtype. Journal of anxiety disorders, 18(4), 531-45. PMID: 15149712.

Spinks, R., Caspers, K., Langbehn, D. & Cadoret, R. J. (2004). The Influence of Genetic Risk for Substance Abuse of Antisociality on School Achievement. The Fourth Annual Guze Symposium on Alcoholism.

Langbehn, D. R., Philibert, R., Caspers, K. M. & Cadoret, R. J. (2004). Interactions between a 124-bp allele at D2s2944 and Alcoholism/Sociopathy Elevate Lifetime Rates of Major Depression. The Fourth Annual Guze Symposium on Alcoholism.

Langbehn, D. R., Brinkman, R. R., Falush, D., Paulsen, J. S. & Hayden, M. R. (2004). A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length. Clinical genetics, 65(4), 267-77. PMID: 15025718.

Hoth, K. F., Stout, J. C., Johnson, S. A., Langbehn, D., Mikos, A., Paulsen, J. S. & the Huntington Study, G. (2004). Simple and choice reaction time is associated with estimated nearness to symptom onset in presymptomatic Huntington's Disease. pp. 71. Presented at the 32nd Annual Meeting of the International Neuropsychological Society.

Rusinak, J. D., Alexander, B., Cook, B. L. & Langbehn, D. R. (2004). A Placebo-controlled trial of Amiloride Versus Hydrochlorothiazidein the Treatment of Lithium-induced Polyuria. University of Iowa College of Pharmacy Research Day.

Stout, J. C., Paulsen, J. S., Langbehn, D., Ross, C., Johnson, S. A., Aylward, E. & Saint-Cyr, J. A. (2004). Integrating clinical and basic science to reveal the neurobiological prodrome of Huntington's Disease (HD). pp. 122. Presented at the 32nd Annual Meeting of the International Neuropsychological Society.

Paulsen, J. S., Zimbelman, J. L., Hinton, S. C., Langbehn, D. R., Leveroni, C. L., Benjamin, M. L., Reynolds, N. C. & Rao, S. M. (2004). fMRI biomarker of early neuronal dysfunction in presymptomatic Huntington's Disease. AJNR. American journal of neuroradiology, 25(10), 1715-21. PMID: 15569736.

Spinks, R., Caspers, K. & Langbehn, D. (2004). The Influence of Genetic Risk of Substance Abuse on School Achievement. SACNAS National Conference.

Caspers, K., Langbehn, D., Spinks, R., Yucius, R. & Cadoret, R. (2004). Biological risk for psychopathology and the moderating role of environmental: Opportunities for intervention and prevention. Presented at the 18th Annual Forensic Conference: Adult antisocial behaviour: Where does it come from and what can we do about it?.

Aylward, E., Langbehn, D., Stout, J. C., Johnson, S. A. & Paulsen, J. S. (2004). Association between cognitive tests and striatal volume in presymptomatic Huntington's disease. Presented at the 2004 Annual Meeting of the Cognitive Neuroscience Society.

Nehl, C., Paulsen, J. S., Johnson, S. A., Langbehn, D., Reese, R., Stout, J. C. & the Huntington Study, G. (2004). Early changes in psychomotor speed in presymptomatic Huntington's Disease. pp. 71. Presented at the 32nd Annual Meeting of the International Neuropsychological Society.

Paulsen, J. S., Stout, J. C., Guttman, M., Aylward, E., Hayden, M. R., Ross, C., Nance, M. A., Langbehn, D., Kayson, E. P., Kieburtz, K., Shoulson, I. & The Huntington Study, G. (2004). A worldwide study of presymptomatic Huntington's Disease (HD). pp. 122. Presented at the 32nd Annual Meeting of the International Neuropsychological Society.

Ross, C., Aylward, E. H., Stout, J. C., Biglan, K., Hayden, M. R., Shoulson, I., Langbehn, D. R., Paulsen, J. S. & the Huntington Study, G. (2004). Clinical and radiographic features of the presymptomatic individuals carrying an expanded CAG repeat in the Huntington's Disease gene: Analysis of baseline characteristics of the Predict-HD cohort. Presented at the 56th Annual Meeting of the American Academy of Neurology.

Noyes, R., Stuart, S. P., Langbehn, D. R., Happel, R. L., Longley, S. L., Muller, B. A. & Yagla, S. J. (2003). Test of an interpersonal model of hypochondriasis. Psychosomatic medicine, 65(2), 292-300. PMID: 12651997.

Riggins-Caspers, K. M., Cadoret, R. J., Knutson, J. F. & Langbehn, D. (2003). Biology-environment interaction and evocative biology-environment correlation: contributions of harsh discipline and parental psychopathology to problem adolescent behaviors. Behavior genetics, 33(3), 205-20. PMID: 12837013.

Langbehn, D. R., Cadoret, R. J., Caspers, K., Troughton, E. P. & Yucuis, R. (2003). Genetic and environmental risk factors for the onset of drug use and problems in adoptees. Drug and alcohol dependence, 69(2), 151-67. PMID: 12609696.

Philibert, R., Caspers, K., Langbehn, D., Troughton, E. P., Yucuis, R., Sandhu, H. K. & Cadoret, R. J. (2003). The association of the D2S2944 124 bp allele with recurrent early onset major depressive disorder in women. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 121B(1), 39-43. PMID: 12898573.

Cadoret, R. J., Langbehn, D., Caspers, K., Troughton, E. P., Yucuis, R., Sandhu, H. K. & Philibert, R. (2003). Associations of the serotonin transporter promoter polymorphism with aggressivity, attention deficit, and conduct disorder in an adoptee population. Comprehensive psychiatry, 44(2), 88-101. PMID: 12658617.

Noyes, R., Stuart, S., Langbehn, D. R., Happel, R. L., Longley, S. L. & Yagla, S. J. (2002). Childhood antecedents of hypochondriasis. Psychosomatics, 43(4), 282-9. PMID: 12189253.

Sarah, H., Douglas, L., Jefferey, D. & William, S. (2002). Evaluation of Personality Disorder Diagnoses Using Cognitive Diagnosis Modeling. The 67th Annual Meeting of the Psychometric Society was held on the campus of the University of North Carolina at Chapel Hill.

Noyes, R., Stuart, S., Longley, S. L., Langbehn, D. R. & Happel, R. L. (2002). Hypochondriasis and fear of death. The Journal of nervous and mental disease, 190(8), 503-9. PMID: 12193834.

Philibert, R., Caspers, K., Langbehn, D., Troughton, E. P., Yucuis, R., Sandhu, H. K. & Cadoret, R. J. (2002). The association of a HOPA polymorphism with major depression and phobia. Comprehensive psychiatry, 43(5), 404-10. PMID: 12216017.

Langbehn, D. R. (2001). The Iowa Personality Disorder Screen. In A Handbook of Pschological Tests. Edwin Mellen Press.

Noyes, R., Langbehn, D. R., Happel, R. L., Stout, L. R., Muller, B. A. & Longley, S. L. (2001). Personality dysfunction among somatizing patients. Psychosomatics, 42(4), 320-9. PMID: 11496021.

Langbehn, D. R., Cadoret, R. J. (2001). The adult antisocial syndrome with and without antecedent conduct disorder: comparisons from an adoption study. Comprehensive psychiatry, 42(4), 272-82. PMID: 11458301.

Langbehn, D. R. (2000). Comments on Donahue, RMJ (1999), 'A Note on Information Seldom Reported Via the P Value'". Am Stat, 54, 227.

Langbehn, D. R. (2000). Comments on Ludbrok, J. and Dudley, H. (1998), "Why Permutation Tests are Superior to t and F Tests in Biomedical Research'". Am Stat, 52, 127-132.

Langbehn, D. R., Alexander, B. (2000). Increased risk of side-effects in psychiatric patients treated with clozapine and carbamazepine: a reanalysis. Pharmacopsychiatry, 33(5), 196. PMID: 11071023.

Rohland, B. M., Langbehn, D. R. & Rohrer, J. E. (2000). Relationship between service effectiveness and satisfaction among persons receiving Medicaid mental health services. Psychiatric services (Washington, D.C.), 51(2), 248-50. PMID: 10655013.

Langbehn, D. R., Pfohl, B. M., Reynolds, S., Clark, L. A., Battaglia, M., Bellodi, L., Cadoret, R., Grove, W., Pilkonis, P. & Links, P. (1999). The Iowa Personality Disorder Screen: development and preliminary validation of a brief screening interview. Journal of personality disorders, 13(1), 75-89. PMID: 10228929.

Langebehn, D. R. (1999). Discrimination via the unweighted sum of predictors. Program and Abstracts, 1999 Spring Meeting of the International Biometric Society Eastern North American Region.

Noyes, R., Langbehn, D. R., Happel, R. L., Sieren, L. R. & Muller, B. A. (1999). Health Attitude Survey. A scale for assessing somatizing patients. Psychosomatics, 40(6), 470-8. PMID: 10581974.

Rohland, B. M., Langbehn, D. R. (1998). Self report of mental health service use in rural versus urban recipients under Medicaid fee-for-service (letter). Psych Serv, 49, 107-108.

Rohland, B. M., Langbehn, D. R. (1998). Use of mental health services in rural areas. Psychiatric services (Washington, D.C.), 49(1), 107-8. PMID: 9444693.

Langbehn, D. R., Cadoret, R. J., Yates, W. R., Troughton, E. P. & Stewart, M. A. (1998). Distinct contributions of conduct and oppositional defiant symptoms to adult antisocial behavior: evidence from an adoption study. Archives of general psychiatry, 55(9), 821-9. PMID: 9736009.

Langbehn, D. R., Woolson, R. F. (1997). Discriminant analysis using the unweighted sum of binary variables: a comparison of model selection methods. Statistics in medicine, 16(23), 2679-700. PMID: 9421869.

Langbehn, D. R., Woolson, R. F. (1997). Discrimination using the unweighted sum of binary variables. 1997 Spring Meeting of the International Biometric Society Eastern North American Region.

Rohland, B. M., Langbehn, D. R. (1997). Self-reported life satisfaction. The American journal of psychiatry, 154(10), 1478-9. PMID: 9326847.

Langbehn, D. R., Cadoret, R. J., Yates, W. R., Troughton, E. P. & Stewart, M. A. (1997). A partially heritable oppositional factor predicts adult antisocial symptoms separately from a conduct factor in an adoption study. pp. 168. New Research Program & Abstracts. Presented at the American Psychiatric Association 150th Annual Meeting.

Rohland, B. M., Langbehn, D. R. & Rohrer, J. E. (1996). Satisfaction as a System Performance Indicator in Persons with Schizophrenia. pp. 277-8. Presented at the American Psychiatric Association 149th Annual Meeting.

Langbehn, D. R. (1996). A comparison of various approaches to model selection and the performance of these models relative to optimally weighted techniques. Bound at University of Iowa Libraries.

Cadoret, R. J., Winokur, G., Langbehn, D., Troughton, E., Yates, W. R. & Stewart, M. A. (1996). Depression spectrum disease, I: The role of gene-environment interaction. The American journal of psychiatry, 153(7), 892-9. PMID: 8659611.

Rohland, B. M., Langbehn, D. R. & Rohrer, J. E. (1995). Characteristics of the Medicaid Population of Iowa Who Receive Mental Health Services: A Managed Mental Health Care Pre-Implementation Survey. Poster presented at the APA Institute on Psych Serv.

Gaffney, G., Langbehn, D., Troutman, B., Rohland, B. M. & Hollingsworth, B. (1995). Characteristics of the Medicaid population of Iowa who receive mental health services: A managed mental health care pre-implementation survey - Report of child survey. Submitted to the Iowa Department of Human Services Mental Health Division.

Rohland, B. M., Langbehn, D., Rohrer, J. E., Hradek, B., Flaum, M., Gaffney, G., Troutman, B. & Hollingsworth, B. (1995). Characteristics of the Medicaid population of Iowa who receive mental health services: A managed mental health care pre-implementation survey. Submitted to the Iowa Department of Human Services Mental Health Division.

Pfohl, B., Langbehn, D. (1993). The detection of personality variables relevant to the treatment of depression in primary care: A review of literature. Non-published review commissioned by the U.S. Agency for Healthcare Policy and Research 1991. Cited as a contributing source in Depression in Primary Care, US Agency for Healthcare Policy and Research.

Langbehn, D. R., Pfohl, B. (1993). Clinical correlates of self-mutilation among psychiatric inpatients. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 5(1), 45-51. PMID: 8348198.

Pfohl, B., Langbehn, D. (1992). The relationship between tridimensional personality questionnaire scores and axis II. pp. 270. American Psychiatric Association 145th Annual Meeting CME Syllabus and Proceedings Summary.

Langbehn, D., Pfohl, B. (1991). Clinical correlates of nonsuicidal self-injury. pp. 96. American Psychiatric Association 144th Annual Meeting New Research Programs and Abstracts.

Fincham, R. W., Lagbehn, D. R. (1990). Ictal catatonia: A case report. American Epilepsy Society Annual Meeting Abstracts.