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David W. Dick, PhD

Clinical Professor of Radiology - Division of Nuclear Medicine

Introduction

Dr. Dick's work focuses on the production of radionuclides for use in positron emission tomography (PET) as well as the design and implementation of radiosynthetic methods for PET radiotracers used in cancer and neurology.

Current Positions

  • Clinical Professor of Radiology - Division of Nuclear Medicine
  • Clinical Professor of Pharmaceutical Sciences and Experimental Therapeutics

Education

  • BS in Physics, Western Washington University, Bellingham, Washington, United States
  • MS in Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin, United States
  • PhD in Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin, United States

Center, Program and Institute Affiliations

Research Interests

  • Design and implementation of radiosynthetic methods for PET radiotracers.
  • Design of equipment for novel synthesis of radiotracers.
  • Develop and maintain regulatory approval for PET radio tracers produced at the University of Iowa PET Imaging Center.
  • Production of nonstandard PET radioisotopes.
  • Using single-mode microwave cavities for radiochemical syntheses.

Selected Publications

  • Yuan F, Gasser GN, Lemire E, Montoro DT, Jagadeesh K, Zhang Y, Duan Y, Ievlev V, Wells KL, Rotti PG, Shahin W, Winter M, Rosen BH, Evans I, Cai Q, Yu M, Walsh SA, Acevedo MR, Pandya DN, Akurathi V, Dick DW, Wadas TJ, Joo NS, Wine JJ, Birket S, Fernandez CM, Leung HM, Tearney GJ, Verkman AS, Haggie PM, Scott K, Bartels D, Meyerholz DK, Rowe SM, Liu X, Yan Z, Haber AL, Sun X, Engelhardt JF. Transgenic ferret models define pulmonary ionocyte diversity and function. Nature. 2023 Sep;621(7980):857-867. doi: 10.1038/s41586-023-06549-9. Epub 2023 Sep 20. PMID: 37730992; PMCID: PMC10533402.
  • Carter, C. S., Huang, S., Searby, C., Cassaidy, B., Miller, M., Grzesik, W., Piorczynski, T. B., Pak, T. K., Walsh, S., Acevedo, M., Zhang, Q., Mapuskar, K., Milne, G., Hinton, Jr, A. O., Guo, D. F., Weiss, R. M., Bradberry, K., Taylor, E. B., Rauckhorst, A., Dick, D., Akurathi, V., Falls-Hubert, K., Wagner, B., Carter, W., Wang, K., Norris, A. W., Rahmouni, K., Buettner, G. R., Hansen, J. M., Spitz, D. R., Abel, E. D. & Sheffield, V. C. (2021). Counterpoint regarding an alternative hypothesis for why exposure to static magnetic and electric fields treat type 2 diabetes. American journal of physiology. Endocrinology and metabolism. DOI: 10.1152/ajpendo.00110.2021. PMID: 33843282.
  • Carter, C. S., Huang, S., Searby, C., Cassaidy, B., Miller, M., Grzesik, W., Piorczynski, T. B., Pak, T. K., Walsh, S., Acevedo, M., Zhang, Q., Mapuskar, K., Milne, G., Hinton, Jr, A. O., Guo, D. F., Weiss, R. M., Bradberry, K., Taylor, E. B., Rauckhorst, A., Dick, D., Akurathi, V., Falls-Hubert, K., Wagner, B., Carter, W., Wang, K., Norris, A. W., Rahmouni, K., Buettner, G. R., Hansen, J. M., Spitz, D. R., Abel, E. D. & Sheffield, V. C. (2021). Response to: An alternative hypothesis for why exposure to static magnetic and electric fields treats type 2 diabetes. American journal of physiology. Endocrinology and metabolism. DOI: 10.1152/ajpendo.00119.2021. PMID: 33843283.
  • Carter, C. S., Huang, S. C., Searby, C. C., Cassaidy, B., Miller, M. J., Grzesik, W. J., Piorczynski, T. B., Pak, T. K., Walsh, S. A., Acevedo, M., Zhang, Q., Mapuskar, K. A., Milne, G. L., Hinton, Jr, A. O., Guo, D. F., Weiss, R., Bradberry, K., Taylor, E. B., Rauckhorst, A. J., Dick, D. W., Akurathi, V., Falls-Hubert, K. C., Wagner, B. A., Carter, W. A., Wang, K., Norris, A. W., Rahmouni, K., Buettner, G. R., Hansen, J. M., Spitz, D. R., Abel, E. D. & Sheffield, V. C. (2020). Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes. (Vols. 32). (6), pp. 1076. Cell metabolism. DOI: 10.1016/j.cmet.2020.11.001. PMID: 33264599.
  • Carter, C. S., Huang, S. C., Searby, C. C., Cassaidy, B., Miller, M. J., Grzesik, W. J., Piorczynski, T. B., Pak, T. K., Walsh, S. A., Acevedo, M., Zhang, Q., Mapuskar, K. A., Milne, G. L., Hinton, A. O., Guo, D. F., Weiss, R., Bradberry, K., Taylor, E. B., Rauckhorst, A. J., Dick, D. W., Akurathi, V., Falls-Hubert, K. C., Wagner, B. A., Carter, W. A., Wang, K., Norris, A. W., Rahmouni, K., Buettner, G. R., Hansen, J. M., Spitz, D. R., Abel, E. D. & Sheffield, V. C. (2020). Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes. Cell Metabolism 32 (4) 561-574.e7. DOI: 10.1016/j.cmet.2020.09.012.
  • Ghobrial, S. N., Menda, Y., Zamba, G. K., Mott, S. L., Gaimari-Varner, K., Dick, D., Dillon, J., Howe, J. R., Graham, M., Sunderland, J., Bellizzi, A., O'Dorisio, T. M. & O'Dorisio, M. S. (2020). Prospective Analysis of the Impact of 68Ga-DOTATOC Positron Emission Tomography-Computerized Axial Tomography on Management of Pancreatic and Small Bowel Neuroendocrine Tumors. Pancreas 49 (8) 1033-1036. DOI: 10.1097/MPA.0000000000001625.
  • Gee, A. D., Andersson, J., Bhalla, R., Choe, Y. S., Dick, D. W., Herth, M. M., Hostetler, E. D., Jáuregui-Haza, U. J., Huang, Y. Y., James, M. L., Jeong, J. M., Korde, A., Kuge, Y., Kung, H. F., Lapi, S. E., Osso, J. A., Parent, E., Patt, M., Pricile, E. F., Riss, P. J., Santos-Oliveira, R., Taylor, S., Vasdev, N., Vercouillie, J., Wadsak, W., Yang, Z., Zhu, H. & Scott, P. J. (2020). Training the next generation of radiopharmaceutical scientists. (Vols. 88-89). pp. 10-13. Nuclear Medicine and Biology. DOI: 10.1016/j.nucmedbio.2020.06.004.
  • Brugarolas, P., Comstock, J., Dick, D. W., Ellmer, T., Engle, J. W., Lapi, S. E., Liang, S. H., Parent, E. E., Kishore Pillarsetty, N. V., Selivanova, S., Sun, X., Vavere, A. & Scott PJH (2020). Fifty Years of Radiopharmaceuticals. Journal of nuclear medicine technology 48 (Suppl 1) 34S-39S. PMID: 32605944.
  • Mixdorf, J. C., Sorlin, A. M., Dick, D. W. & Nguyen, H. M. (2019). Iridium-Catalyzed Radiosynthesis of Branched Allylic [18F]Fluorides. Organic Letters 21 (1) 60-64. DOI: 10.1021/acs.orglett.8b03496. PMID: 30575403.
  • Do, R. K. & Dick, D. W. (2018). PET/MRI Safety Considerations. pp. 115-130. Heidelberg: PET/MRI in Oncology.