Geeta Lal, MD, MSc

Portrait
Associate Professor of Surgery
Associate Chief Quality Officer, Adult Inpatient
Endocrine and Breast Oncology Surgeon
Co-Director, 4JPP, Medical/Surgical Oncology Inpatient Unit
Co-Leader of Endocrine MOG
Associate Professor of Surgery - Surgical Oncology and Endocrine Surgery

Contact Information

Primary Office: 4641 JCP
Iowa City, IA 52242
319-356-1327

Education

BS, Summa cum Laude, McMaster University
MD, Honors, University of Toronto
MSc, University of Toronto and The Samuel Lunenfeld Research Institute

Resident, General Surgery, University of Toronto
Fellow, Endocrine Surgical Oncology, Mt. Zion Medical Center, University of California, San Francisco

Licensure and Certifications

Board Certified, General Surgery - American Board of Surgery
Iowa Medical License - Iowa Board of Medical Examiners
Royal College of Physicians and Surgeons of Canada

Research Summary

Geeta Lal Surgical Oncology Laboratory- http://www.medicine.uiowa.edu/lallab/

Publications

Wu, V. T., Lorenzen, A. W., Beck, A. C., Reid, V. J., Sugg, S. L., Howe, J. R., Pollard, J. H., Lal, G. & Weigel, R. J. (2017). Comparative analysis of radioactive iodine versus thyroidectomy for definitive treatment of Graves disease. Surgery, 161(1), 147-155. PMID: 27863789.

Gómez-Contreras, P., Ramiro-Díaz, J. M., Sierra, A., Stipp, C., Domann, F. E., Weigel, R. J. & Lal, G. (2017). Extracellular matrix 1 (ECM1) regulates the actin cytoskeletal architecture of aggressive breast cancer cells in part via S100A4 and Rho-family GTPases. Clinical & experimental metastasis, 34(1), 37-49. PMID: 27770373.

Park, J. M., Wu, T., Cyr, A. R., Woodfield, G. W., De Andrade, J. P., Spanheimer, P. M., Li, T., Sugg, S. L., Lal, G., Domann, F. E., Zhang, W. & Weigel, R. J. (2015). The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis. Oncogene, 34(50), 6105-14. PMID: 25772240.

Bhama, A. R., Smith, R. J., Robinson, R. A., Weigel, R. J., Sugg, S. L., Howe, J. R. & Lal, G. (2014). Preoperative evaluation of thyroglossal duct cysts: children versus adults--is there a difference?. American journal of surgery, 207(6), 902-6. PMID: 24246260.

Lal, G. (2014). To do or not to do: neck ultrasound and the detection of thyroid pathology in patients with primary hyperparathyroidism. The Journal of surgical research, 190(2), 415-6. PMID: 24969545.

Lal, G., Contreras, P. G., Kulak, M., Woodfield, G., Bair, T., Domann, F. E. & Weigel, R. J. (2013). Human Melanoma cells over-express extracellular matrix 1 (ECM1) which is regulated by TFAP2C. PloS one, 8(9), e73953. PMID: 24023917.

Lal, G., Clark, O. H. (2013). Thyroid, Parathyroid and Adrenal.

Bhama, A. R., Lal, G. (2013). Autoimmune rheumatic disease (polymyositis & dermatomyositis) associated with papillary thyroid carcinoma: Case series and review of the literature. World Journal of Endocrine Surgery.

Spanheimer, P. M., Stoltze, A. J., Howe, J. R., Sugg, S. L., Lal, G. & Weigel, R. J. (2013). Do giant parathyroid adenomas represent a distinct clinical entity?. Surgery, 154(4), 714-8; discussion 718-9. PMID: 23978594.

Carr, J. C., Spanheimer, P. M., Rajput, M., Dahdaleh, F. S., Lal, G., Weigel, R. J., Sugg, S. L., Liao, J. & Howe, J. R. (2013). Discriminating pheochromocytomas from other adrenal lesions: the dilemma of elevated catecholamines. Annals of surgical oncology, 20(12), 3855-61. PMID: 23884753.

Khullar, p., Lal, G. (2012). Hyperthyroidism, thyroiditis and non-toxic goiter.

Lal, G., Groff, M., Howe, J., Weigel, R., Sugg, S. & Lynch, C. (2012). Risk of second primary thyroid cancer following another malignancy: Trends in a population-based study. Ann Surg Oncol.

O'Malley, Y., Lal, G., Howe, J. R., Weigel, R. J., Komorowski, R. A., Shilyansky, J. & Sugg, S. L. (2012). Invasion in follicular thyroid cancer cell lines is mediated by EphA2 and pAkt. Surgery, 152(6), 1218-24. PMID: 23158188.

O’Malley, Y., Lal, G., Howe, J. R., Weigel, R. J. & Sugg, S. L. (2012). Invasion in follicular thyroid cancer (FTC) cell lines is mediated by EphA2 and p-Akt. Surgery, 152(6), 1218-24.

Lal, G., Bhama, A. Thyroidectomy. In Chassin's Operative Strategy in General Surgery: An Expositive Atlas. (4) An Expositive Atlas.

Lal, G., Khullar, P. Hyperthyroidism, thyroiditis and non-toxic goiter.

Lal, G., Groff, M., Howe, J. R., Weigel, R. J., Sugg, S. L. & Lynch, C. F. (2012). Risk of subsequent primary thyroid cancer after another malignancy: latency trends in a population-based study. Annals of surgical oncology, 19(6), 1887-96. PMID: 22227921.

Lal, G., Fang, S. (2011). Parathyroid cancer. (Vols. 1). pp. 36-43. Endocr Pract.

Lal, G., Weigel, R., Kirby, P., Miron, J. & Royer, N. (2011). Incidental finding of Composite pheochromocytoma-ganglioneuroma: Successful management after emergent appendectomy and review of the literature. (Vols. 3). (1), pp. 34-44. World Journal of Endocrine surgery.

Lal, G., Spanheimer, P., Sugg, S., Howe, J. & Weigel, R. (2011). Surveillance and intervention following thyroid lobectomy. (Vols. 18). (6), pp. 1729-33. Ann Surg Oncol.

Spanheimer, P. M., Sugg, S. L., Lal, G., Howe, J. R. & Weigel, R. J. (2011). Surveillance and intervention after thyroid lobectomy. Annals of surgical oncology, 18(6), 1729-33. PMID: 21246403.

Fang, S. H., Lal, G. (2011). Parathyroid cancer. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 17 Suppl 1, 36-43. PMID: 21454239.

Lal, G., Fairchild, T., Howe, J. R., Weigel, R. J., Sugg, S. L. & Menda, Y. (2010). PET-CT scans in recurrent or persistent differentiated thyroid cancer: is there added utility beyond conventional imaging?. Surgery, 148(6), 1082-9; discussion 1089-90. PMID: 21134537.

Lal, G., Weigel, R., Fang, S., Guidroz, J., O’Malley, Y., Sugg, S. & Howe, J. (2010). Expansion of a cell population expressing Stem cell markers in parathyroid glands from patients with Hyperparathyroidism. (Vols. 251). (1), pp. 107-13. Ann Surg.

Lal, G., Gardner, D., Greenspan, F. & Clark, O. (2010). Endocrine Surgery. In Basic and Clinical Endocrinology. (8) McGraw-Hill Companies.

Lal, G., Clark, O. (2010). Management of Differentiated Thyroid cancers – Updated guidelines from the American Thyroid Association.

Lal, G., Fairchild, T., Howe, J., Weigel, R., Sugg, S. & Menda, Y. (2010). PET-CT for recurrent or persistent differentiated thyroid cancer – Is there added utility beyond conventional imaging?. (Vols. 148). (6), pp. 1082-9. Surgery.

Lal, G., Brunicardi & Clark, O. (2009). Thyroid, Parathyroid and Adrenal. In Schwartz’s Principles of Surgery. (9) McGraw-Hill Companies.

Lal, G., Hashimi, S., Smith, B. J., Zhang, L., Lynch, C., Robinson, R. A. & Weigel, R. J. (2009). Extracellular Matrix 1 (ECM1) expression is a novel prognostic marker for poor long-term survival in breast cancer – a hospital-based cohort study in Iowa. (Vols. 16). (8), pp. 2280-7. Ann Surg Oncol.

Lal, G., Nowell, A., Liao, J., Sugg, S., Weigel, R. & Howe, J. (2009). Determinants of survival in patients with calciphylaxis – a multivariate analysis. (Vols. 146). (6), pp. 1028-34. Surgery.

Lal, G., Weigel, R., Howe, J., Sugg, S., Sue O'Dorisio, M., O'Dorisio, T. & Calva, D. (2009). When is prophylactic thyroidectomy indicated for patients with the RET codon 609 mutation?. (Vols. 16). (8), pp. 2237-44. Ann Surg Oncol.

Lal, G., Dawson, Scott-Conner & Maurice, M. (2008). Parathyroidectomy. In Operative Anatomy. (3) Lippincott-Williams and Wilkins.

Lal, G., O’Dorisio, T., McDougall, I., Weigel, R. & Abeloff (2008). Cancer of the Endocrine system. In Abeloff’s Clinical Oncology. (4) Elsevier Publications.

Lal, G. (2008). Large adrenal incidentaloma. In Case Studies in Minimal Access Surgery: A companion to the SAGES manual. Springer.

Lal, G., Domann, F., Padmanabha, L., Provenzano, M. & Fitzgerald, M. (2008). Epigenetic regulation of 14-3-3s expression by aberrant promoter methylation in thyroid carcinoma. (Vols. 267). (1), pp. 165-74. Cancer Lett.

Lal, G., Maurice, M., Scott-Conner & Dawson (2008). Thyroidectomy. In Operative Anatomy. (3) Lippincott-Williams and Wilkins.

Lal, G., Padmanabha, L., Nicholson, R., Smith, B. J., Zhang, L., Robinson, R. & O'Dorisio, M. (2008). ECM1 expression in malignant thyroid neoplasms: A comparison of real-time PCR with immunohistochemistry. (Vols. 149). (1), pp. 62-8. J Surg Res (epub 2007).

Adam, L., Calva-Cerqueira, D., Howe, J., Smith, B. & Lal, G. (2008). Role for limited neck exploration in young adults with apparently sporadic primary hyperparathyroidism. (Vols. 32). (7), pp. 1518-24. World J Surg.

Lal, G., Gardner, D., Clark, O. & Greenspan, F. (2007). Endocrine Surgery. In Basic and Clinical Endocrinology. (8) McGraw-Hill Companies.

Lal, G., Clark, O. H. (2007). Parathyroidectomy -- The bilateral approach. In A. Isgor (Eds.) The Parathyroid. Avrupa publishers (Turkey).

Lal, G., Clark, O. H. (2007). Basic concepts of parathyroid surgery. In A. Isgor (Eds.) The Parathyroid. Avrupa publishers (Turkey).

Lal, G., Padmanabha, L., Nicholson, R., Smith, B. J., Zhang, L., Robinson, R. & O’Dorisio, M. S. (2007). ECM1 expression in malignant thyroid neoplasms: A comparison of real-time PCR with immunohistochemistry. J Surg Res.

Calva-Cerqueira, D., Smith, B. J., Hostetler, M. L., Lal, G., Menda, Y., O'Dorisio, T. M. & Howe, J. (2007). Minimally invasive parathyroidectomy and preoperative MIBI scans: correlation of gland weight and preoperative PTH. (Vols. 205). (4 Suppl), pp. S38-44. J Am Coll Surg.

Howe, J., Larsen-Haidle, J., Lal, G., Bair, J., Song, C., Pechman, B. & Lynch, H. T. (2007). ENG Mutations in SMAD4/BMPR1A Mutation Negative Patients with Juvenile Polyposis. (Vols. 71). pp. 91-92. Clinical Genetics.

Lal, G., Padmanabha, L., Nicholson, R., Smith, B. J., Howe, J., O'Dorisio, M. & Domann, F. E. (2006). RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinomas. (Vols. 107). (12), pp. 2752-9. Cancer.

Kim, W., Bartel, T., Juweid, M., Lal, G. & Graham, M. M. (2006). Renal cyst uptake following I-131 treatment for thyroid cancer. (Vols. 16). (12), pp. 1315-6. Thyroid.

Lal, G., Clark, O. H. (2005). Thyroiditis. In O. H. Clark , D. Q-Y , E. Kebebew (Eds.) Textbook of Endocrine Surgery 2nd edition. Elsevier/Saunders.

Lal, G., Ituarte, P., Kebebew, E., Siperstein, A., Duh, Q. Y. & Clark, O. H. (2005). Should total thyroidectomy become the preferred procedure for surgical management of Graves' disease?. (Vols. 15). (6), pp. 569-74. Thyroid.

Lal, G., Clark, O. H. (2005). Diagnosis of primary hyperparathyroidism and indications for surgery. In O. H. Clark , D. Q-Y , E. Kebebew (Eds.) Textbook of Endocrine Surgery 2nd edition. Elsevier/Saunders.

Lal, G., Clark, O. H. (2004). Thyroid, Parathyroid and Adrenal. In Brunicardi (Eds.) Schwartz's Principles of Surgery 8th edition. McGraw-Hill Companies.

Lal, G., Clark, O. H. (2003). Endocrine Surgery. In F. Greenspan , D. Gardner (Eds.) Basic and Clinical Endocrinology 7th edition. McGraw-Hill Companies.

Clark, O. H., Lal, G. (2003). Novel method for control of mediastinal bleeding during thyroidectomy for substernal goiter. (Vols. 196). (5), pp. 818-20. J Am Coll Surg.

Haciyanli, M., Lal, G., Morita, E., Duh, Q. Y., Kebebew, E. & Clark, O. H. (2003). Accuracy of preoperative localization studies and intraoperative parathyroid hormone assay in patients with primary hyperparathyroidism and double adenoma. (Vols. 197). (5), pp. 739-46. J Am Coll Surg.

Lal, G., Clark, O. H. (2003). Primary hyperparathyroidism -- Controversies in surgical management. (Vols. 14). (9), pp. 417-22. Trends Endocrinol Metab.

Lal, G., Duh, Q. (2003). Laparoscopic Adrenalectomy -- Indications and Technique. (Vols. 12). (2), pp. 105-23. Surg Oncol.

Lal, G., Brennan, T. M., Hambleton, J. & Clark, O. H. (2003). Coagulopathy, marantic endocarditis and cerebrovascular accidents as paraneoplastic features in Medullary thyroid cancer. (Vols. 13). (6), pp. 601-5. Thyroid.

Ghadirian, P., Liu, G., Gallinger, S., Schmocker, B., Paradis, A. J., Lal, G., Brunet, J. S., Foulkes, W. D. & Narod, S. A. (2002). Risk of pancreatic cancer among individuals with a family history of cancer of the pancreas. (Vols. 97). (6), pp. 807-10. Int J Cancer.

Lal, G., Gallinger, S. (2001). Genetics of pancreatic cancer -- What are the risks?. The Canadian Journal of CME, 13(11), 191-209.

Lal, G., Ash, C., Hay, K., Redston, M., Kwong, E., Hancock, B., Mak, T., Kargman, S., Evans, J. F. & Gallinger, S. (2001). Suppression of intestinal polyps in Msh2 deficient and non-Msh2 deficient Min mice by a specific cyclooxygenase-2 inhibitor and by a dual cyclooxygenase-1/2 inhibitor. (Vols. 61). (16), pp. 6131-6. Cancer Res 15.

Liu, G., Ghadirian, P., Vesprini, D., Hamel, N., Paradis, A. J., Lal, G., Gallinger, S., Narod, S. A. & Foulkes, W. D. (2000). Polymorphisms in GSTM1, GSTT1 and CYP1A1 and risk of pancreatic anenocarcinoma. (Vols. 82). (10), pp. 1646-9. Br J Cancer.

Lal, G., Liu, G., Schmocker, B., Kaurah, P., Ozcelik, H., Narod, S., Redston, M. & Gallinger, S. (2000). Inherited predisposition to pancreatic adenocarcinoma: Role of family history and germline p16, BRCA1 and BRCA2 mutations. (Vols. 60). (2), pp. 409-16. Cancer Res 15.

Lal, G., Gallinger, S. (2000). Familial adenomatous polyposis. (Vols. 18). (4), pp. 314-23. Semin Surg Oncol.

Lal, G., Liu, L., Hogg, D., Lassam, N., Redston, M. & Gallinger, S. (2000). Patients with both pancreatic adenocarcinoma and melanoma may harbor germline CDKN2A mutations. (Vols. 27). (4), pp. 358-61. Genes Chromosomes Cancer.

Gryfe, R., Di Nicola, N., Lal, G., Gallinger, S. & Redston, M. (1999). Inherited colorectal polyposis and cancer risk of the APC I1307K polymorphism. (Vols. 64). (2), pp. 378-84. Am J Hum Genet.

Carr, M. M., Jamieson, C. G. & Lal, G. (1996). Blue Rubber Bleb Nevus Syndrome. (Vols. 39). (1), pp. 59-62. Cdn J Surg.

Lal, G., Carr, M. M. & Jamieson, C. G. (1994). Pilonidal Sinus Disease: A Review. (Vols. 72). (1), pp. 26-32. UTMJ.