Patrick W. McGonagill, MD
Clinical Associate Professor of Surgery - Acute Care Surgery
Current Positions
- Clinical Associate Professor of Surgery - Acute Care Surgery
Education
- BA in History, Spanish Minor, University of Iowa, Iowa City, Iowa, United States
- MD in Medicine, University of Iowa, Iowa City, Iowa, United States
- Resident in General Surgery, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, United States
- Chief Resident in Administrative Chief - Surgery, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, United States
- Fellow in Surgical Critical Care, University of Minnesota, Minneapolis, Minnesota, United States
Research Interests
- Trauma safety and public policy.
- Surgical and post-surgical infection control.
- Impact of sepsis on innate and adaptive immunity
- Predicting outcomes in trauma patient based on available clinical data
- Pilonidal Disease
Licenses & Certifications
- General Surgery, American Board of Surgery, United States
- Iowa Board of Medicine, State of Iowa, Iowa, United States
- Minnesota Medical License, State of Minnesota, Minnesota, United States
- Advanced Surgical Skills for Exposure in Trauma (ASSET) Instructor, American College of Surgeons
Selected Publications
- Barrios EA, Mazer MB, McGonagill P, Bergmann CB, Goodman MD, Gould R, Rao M, Polcz V, Davis R, Del Toro D, Dirain M, Dram A, Hale L, Heidarian M, Kucaba TA, Lanz JP, McCray A, Meszaros S, Miles S, Nelson C, Rocha I, Silva EE, Ungaro R, Walton A, Xu J, Zeumer-Spataro L, Drewry A, Liang M, Bible LE, Loftus T, Turnbull I, Efron PA, Remy KE, Brakenridge S, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Adverse Long-Term Outcomes and an Immune Suppressed Endotype in Sepsis Patients with Reduced Interferon-γELISpot: A Multicenter, Prospective Observational Study. medRxiv. 2023 Sep 24;. doi: 10.1101/2023.09.13.23295360. PubMed PMID: 37745385; PubMed Central PMCID: PMC10516075.
- Berton RR, McGonagil PW, Jensen IJ, Ybarra TK, Bishop GA, Harty JT, Griffith TS, Badovinac VP. Sepsis leads to lasting changes in phenotype and function of naïve CD8 T cells. PLoS Pathog. 2023 Oct;19(10):e1011720. doi: 10.1371/journal.ppat.1011720. eCollection 2023 Oct. PubMed PMID: 37824591; PubMed Central PMCID: PMC10597476.
- Barrios EL, Mazer MB, McGonagill PW, Bergmann CB, Goodman MD, Gould RW, Rao M, Polcz VE, Davis RJ, Del Toro DE, Dirain ML, Dram A, Hale LO, Heidarian M, Kim CY, Kucaba TA, Lanz JP, McCray AE, Meszaros S, Miles S, Nelson CR, Rocha IL, Silva EE, Ungaro RF, Walton AH, Xu J, Zeumer-Spataro L, Drewry AM, Liang M, Bible LE, Loftus TJ, Turnbull IR, Efron PA, Remy KE, Brakenridge SC, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Adverse outcomes and an immunosuppressed endotype in septic patients with reduced IFN-γ ELISpot. JCI Insight. 2024 Jan 23;9(2). doi: 10.1172/jci.insight.175785. PubMed PMID: 38100268; PubMed Central PMCID: PMC10906237.
- Kamalumpundi V, Gonzalez Bravo C, Kohn DJ, McGonagill P, Guyton K. Addressing Language Barriers in the Intensive Care Unit: A Case-Based Reflection and Brief Appraisal of the Literature. Cureus. 2024 Mar;16(3):e55646. doi: 10.7759/cureus.55646. eCollection 2024 Mar. PubMed PMID: 38586717; PubMed Central PMCID: PMC10995741.
- Ungaro RF, Xu J, Kucaba TA, Rao M, Bergmann CB, Brakenridge SC, Efron PA, Goodman MD, Gould RW, Hotchkiss RS, Liang M, Mazer MB, McGonagill PW, Moldawer LL, Remy KE, Turnbull IR, Caldwell CC, Badovinac VP, Griffith TS. Development and optimization of a diluted whole blood ELISpot assay to test immune function. J Immunol Methods. 2024 Oct;533:113743. doi: 10.1016/j.jim.2024.113743. Epub 2024 Aug 13. PubMed PMID: 39147231; PubMed Central PMCID: PMC11398710.
- Price AD, Becker ER, Barrios EL, Mazer MB, McGonagill PW, Bergmann CB, Goodman MD, Gould RW, Rao M, Polcz VE, Kucaba TA, Walton AH, Miles S, Xu J, Liang M, Loftus TJ, Efron PA, Remy KE, Brakenridge SC, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Surviving septic patients endotyped with a functional assay demonstrate active immune responses. Front Immunol. 2024;15:1418613. doi: 10.3389/fimmu.2024.1418613. eCollection 2024. PubMed PMID: 39469706; PubMed Central PMCID: PMC11513262.
- Rao M, McGonagill PW, Brackenridge S, Remy KE, Caldwell CC, Hotchkiss RS, Moldawer LL, Griffith TS, Badovinac VP. Functional Immunophenotyping for Precision Therapies in Sepsis. Shock doi: 10.1097/SHK.0000000000002511. [Epub ahead of print] PubMed PMID: 39617419.
- Dornbush C and McGonagill P. Grave robbing, cadaver acquisition evolve from cemetery to classroom. Bulletin of the American College of Surgeons. 2024 Feb 109:2.
- Barrios EL, Mazer MB, McGonagill PW, Bergmann CB, Goodman MD, et al. Adverse outcomes and an immune suppressed endotype in sepsis patients with reduced interferon-γ ELISpot. JCI Insight. 2023 Dec 15:e175785. doi: 10.1172/jci.insight.175785. Online ahead of print. PMID: 38100268
- Serrano E, Voldal EC, Machado-Aranda D, DeUgarte DA, Kao L, Drake T, Winchell R, Cuschieri J, Krishnadasan A, Talan DA, Siparsky N, Ayoung-Chee P, Self WH, McGonagill P, et al. Trial Participation and Outcomes Among English-Speaking and Spanish-Speaking Patients With Appendicitis Randomized to Antibiotics: A Secondary Analysis of the CODA Randomized Clinical Trial. JAMA Surg. 2023 Sep 1;158(9):901-908. doi: 10.1001/jamasurg.2023.2277.PMID: 37379001