Cytogenetics

Gytogenetics Group

Our commitment is to provide high quality cytogenetic services at competitive costs.


Hours:
Weekdays- 8:00 a.m.-5:00 p.m.
Weekends/Holidays- Technologists are on-call during weekends and holidays.

Contact Information:
Phone: 319-356-3877
Fax: 319-353-6704
Pager - Weekends and Holidays: (319) 356-1616 Ask the operator to page 5525.
Pager - Normal Business Hours: (319) 356-1616 Ask the operator to page 5525.

Requisitions:
Comprehensive Hematopathology Analysis Requisition
Constitutional Genetics Pre and Post-Natal Requisition

Reports:  For chromosome analysis, preliminary results are given in 24-48 hours based on 10 cells for specimens with hematological malignancies and newborns.

Final Report Tura-Around-Times:
Chromosome analysis for hematological malignancies - 14 days
Chromosome analysis of newborns - 7 days
Chromosome analysis constitutional studies - 28 days
FISH on blood or bone marrow - 5-7 days
FISH on FFPE slides - 14 days
CMA - 30 days

A written report is mailed or faxed to the referring physician at outside hospitals.

Specimen Shipping:
BONE MARROW – Send in green-top sodium heparin vacutainer. Requires at least 3cc of specimen in a green-topped, sodium heparin vacutainer. Invert tube to mix well. If the appropriate vacutainer is not available, please contact Cytogenetics for alternative instructions. Transport at room temperature.

PARAFFIN EMBEDDED TISSUE – Submit four slides per probe. Sections should be two microns on plus slides. Also submit an H&E slide with the critical region circled.

PERIPHERAL BLOOD - Chromosome study requires 5-10cc of blood for adult patients and a minimum of 2cc for children. Obtain a venous blood specimen in a green-topped, sodium heparin vacutainer. Invert tube to mix well. If the appropriate vacutainer is not available, please contact Cytogenetics for alternative instructions. Transport at room temperature.

TUMOR TISSUE/OTHER TISSUE – Tissues should be obtained as soon after removal as possible. Attempt should be made to obtain viable tissue which is free of bacterial contamination. Place the tissue in a sterile container. DO NOT place tissue in formaldehyde or formalin. Transport at room temperature.

CMA – Requires 3-5cc for adults and children over 1 year and 1-2cc for infants. Obtain a venous blood specimen in a lavender top, EDTA vacutainer. Transport at room temperature or at 4 degrees Celsius.

VOIDED URINE, BLADDER WASH – Collect 40-70 cc and immediately transport to lab in a sterile container. Transport at room temperature or at 4 degrees Celsius.

Shipping Address:
University of Iowa Diagnostic Laboratories (UIDL)
Departmenty of Pathology
200 Hawkins Drive 5231 RCP
Iowa City, IA 52242-1087

Client Services:
Toll-free: 866-844-2522
Local: 319-384-7212
Client Services Fax: 319-384-7213
Billing Fax: 319-356-0729

Consultation is available through our laboratory from board certified clinical/molecular/biochemical geneticists and genetic counselors in the Division of Medical Genetics.

Consultants:
Benjamin Darbro
Benjamin Darbro, MD, PhD
Director, Cytogenetics and Molecular Laboratory
Office: W101 General Hospital
Phone: 319-356-3877
Email: benjamin-darbro@uiowa.edu

Dr. John Bernat
John Bernat, MD, PhD
Office: W125 General Hospital
Phone: 319-356-2675
Email: john-bernat@uiowa.edu

Jamie Nagy
Jaime Nagy, PhD
Office: W101 General Hospital
Phone: 319-356-3877
Email: jaime-nagy@uiowa.edu

Agshin Taghiyev
Agshin Taghiyev, PhD
Office: W101 General Hospital
Phone: 319-356-3878
Email: agshin-taghiyev@uiowa.edu