Cell Biology

Brad A. Amendt, PhD

Martine Dunnwald, PharmD, PhD

  • Mechanisms of IRF6-mediated keratinocyte migration during wound healing
  • Role of cleft-associated genes in wound healing and tissue repair

John F. Engelhardt, PhD 

  • Redox-mediated signal transduction pathways in disease
  • Receptor signaling and endosomal control of NADPH oxidases
  • Cell Biology of adeno-associated virus (AAV) transduction

C. Andrew Frank, PhD

  • Synaptic transmission and muscle-to-nerve retrograde signaling in Drosophila

Masataka Kawai, PhD

  • Molecular mechanisms of force generation in striated muscles
  • Reconstitution of the thin filament in cardiac muscles
  • Positive allosteric effect of tropomyosin on the actomysin interaction 
  • Mechanisms of underlying hypertrophic cardiomyopathy (HCM) 

Fang Lin, MD, PhD

  • Involvement of G protein signaling in the migration of primordial germ cells (PGC)
  • Identification of G proteins and G protein-coupled receptors that regulate gastrulation

Tom Rutkowski, PhD

  • Mechanisms by which cells adapt or succumb to chronic protein misfolding stresses
  • Systems biology of the endoplasmic reticulum stress response—how integration of signals from distinct stress-sensing pathways brings about discrete changes in cellular physiology

Tina Tootle, PhD

  • Mechanisms of prostaglandin-mediated cytoskeleton remodeling during Drosophila oogenesis
  • Border-cell migration as a model for understanding prostaglandin-mediated invasive cell migration

Charles Yeaman, PhD

  • Cellular mechanisms involved in development and maintenance of epithelial-cell polarity
  • Roles of Ras-like GTPases and Exocyst in epithelial membrane trafficking
  • Functions of primary cilia in regulating epithelial-cell growth and differentiation

Sam M. Young, Jr. PhD

  • Cell Biology of Adenovirus transduction
  • Calcium channel trafficking and physiology
  • Regulation of synaptic release and replenishment