Development of 3D printed scaffolds and gene therapies for cleft palate repair
Bone and tissue regeneration using new microRNA biotechnologies
Botand Banfi, MD, PhD
Molecular mechanisms that underlying defects in cystic fibrosis and deafness, with a focus on ROS and NADPH oxidase
Adam Dupuy, PhD
Use of sleeping beauty transposon system to generate tissue specific-models of cancer in mice
John F. Engelhardt, PhD
Development of gene therapies for inherited and environmentally induced diseases
Development of recombinant adeno-associated viral vectors for gene therapy
Investigation of the pathogenesis and treatment of cystic fibrosis lung disease
Mechanisms underlying ischemia/reperfusion injury and applications of gene therapy in the liver
C. Andrew Frank, PhD
Use of Drosophila genetics and pharmacology to understand signaling pathways that link synaptic instability to disorders of the nervous system
Tom Rutkowski, PhD
Mechanistic links between endoplasmic reticulum homeostasis and lipid metabolism in the liver
Mechanisms whereby dysregulation of the ER stress response contributes to diseases of liver function (metabolic syndrome, hepatitis, alcohol steatosis)
Ling Yang, PhD
. Cellular and molecular mechanisms of Nonalcoholic fatty liver disease (NAFLD);
. Organelle function in the context of obesity and diabetes;
. The role of organelle stress responses in maintaining Immuno-metabolic homeostasis in cardiovascular diseases (CVDs)
Charles Yeaman, PhD
Molecular mechanisms underlying renal cystogenesis, with a focus on dysfunction of the primary cilia