Selected recent manuscripts
Ear PH, Li G, Wu M, Abusada E, Bellizzi AM, Howe JR. Establishment and Characterization of Small Bowel Neuroendocrine Tumor Spheroids. Journal of visualized experiments : JoVE. 2019(152). PubMed PMID: 31657801. PMCID: PMC7654522
Umesalma S, Kaemmer CA, Kohlmeyer JL, Letney B, Schab AM, Reilly JA, Sheehy RM, Hagen J, Tiwari N, Zhan F, Leidinger MR, O'Dorisio TM, Dillon J, Merrill RA, Meyerholz DK, Perl AL, Brown BJ, Braun TA, Scott AT, Ginader T, Taghiyev AF, Zamba GK, Howe JR, Strack S, Bellizzi AM, Narla G, Darbro BW, Quelle FW, Quelle DE. RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth. J Clin Invest. 2019;130:1641-53. PubMed PMID: 30721156; PMCID: PMC6436899.
Scott AT, Weitz M, Breheny PJ, Ear PH, Darbro B, Brown BJ, Braun TA, Li G, Umesalma S, Kaemmer CA, Maharjan CK, Quelle DE, Bellizzi AM, Chandrasekharan C, Dillon JS, O'Dorisio TM, Howe JR. Gene Expression Signatures Identify Novel Therapeutics for Metastatic Pancreatic Neuroendocrine Tumors. Clin Cancer Res. 2020;26:2011-21. PubMed PMID: 31937620; PMCID: PMC7165057.
Howe JR. It May not be Too Little or Too Late: Resecting Primary Small Bowel Neuroendocrine Tumors When there is Metastatic Disease (Editorial). Ann Surg Oncol. 2020;27:2583-2585. PMID:32500346
Tran CG, Scott AT, Li G, Sherman S, Ear PH, Howe JR. Metastatic pancreatic neuroendocrine tumors have decreased somatostatin expression and increased Akt signaling. Surgery. 2020 Jun 28:S0039-6060(20)30243-9. doi: 10.1016/j.surg.2020.04.034. Online ahead of print. PMID: 32611516 PMCID: PMC7736292
Tran CG, Sherman S, Scott AT, Ear PH, Chandrasekharan C, Bellizzi AM, Dillon J, O'Dorisio TM, Howe JR. It is Time to Rethink Biomarkers for Surveillance of Small Bowel Neuroendocrine Tumors. Ann Surg Oncol. 2020 Jul 11. doi: 10.1245/s10434-020-08784-0. Online ahead of print. PMID: 32656719 NIHMS1611312
Kaemmer CA, Umesalma S., Maharjan CK, Moose D, Narla G, Mott S, Zamba GKD, Breheny P, Darbro BW, Bellizzi AM, Henry MD, and Quelle DE. Development and comparison of novel bioluminescent mouse models of pancreatic neuroendocrine neoplasm metastasis. Scientific Reports (accepted pending revision).