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Ali Jabbari, MD, PhD, FAAD

Portrait
Associate Professor of Dermatology

Contact Information

Office
40025 Pomerantz Family Pavilion
200 Hawkins Drive
Iowa City, IA 52242
319-356-2856

Primary Office
2110A Medical Laboratories
500 Newton Road
Iowa City, IA 52242
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Lab
2110 Medical Laboratories
500 Newton Road
Iowa City, IA 52242
319-335-1201

Education

BA, Molecular & Cell Biology, University of California, Berkeley
MD/PhD, Medicine-Immunology, University of Iowa
Internship, Internal Medicine, UT Southwestern
Resident, Dermatology, New York University
Fellow, Immunodermatology, Rockefeller University

Licensure and Certifications

Iowa State Medical
Texas State Medical
Fellow - American Academy of Dermatology
Diplomat - American Board of Dermatology
New York State Medical

Publications

Richey, P., Holt, M., Crotts, S. & Jabbari, A. (2019). Pretibial dystrophic epidermolysis bullosa associated with aberrant exon splicing of type VII collagen. (Vols. 5). (9), pp. 779-781. JAAD case reports. PMID: 31516996.

Ortolan, L. S., Kim, S. R., Crotts, S., Liu, L. Y., Craiglow, B. G., Wambier, C., Paschoal, R. S., King, B. A. & Jabbari, A. (2019). IL-12/IL-23 neutralization is ineffective for alopecia areata in mice and humans. The Journal of allergy and clinical immunology. PMID: 31470035.

Petukhova, L., Patel, A. V., Rigo, R. K., Bian, L., Verbitsky, M., Sanna-Cherchi, S., Erjavec, S. O., Abdelaziz, A. R., Cerise, J. E., Jabbari, A. & Christiano, A. M. (2019). Integrative analysis of rare copy number variants and gene expression data in alopecia areata implicates an aetiological role for autophagy. Experimental dermatology. PMID: 31169925.

Borcherding, N., Voigt, A. P., Liu, V., Link, B. K., Zhang, W. & Jabbari, A. (2019). Single-Cell Profiling of Cutaneous T-Cell Lymphoma Reveals Underlying Heterogeneity Associated with Disease Progression. Clinical cancer research : an official journal of the American Association for Cancer Research, 25(10), 2996-3005. PMID: 30718356.

Concha JSS,, Patsatsi, A., Marshak-Rothstein, A., Liu, M. L., Sinha, A. A., Lee, L. A., Merola, J. F., Jabbari, A., Gudjonsson, J. E., Chasset, F., Jarrett, P., Chong, B., Arkin, L., Fernandez, A. P., Caproni, M., Greenberg, S. A., Kim, H. J., Pearson, D. R., Femia, A., Vleugels, R. A., Fiorentino, D., Fujimoto, M., Wenzel, J. & Werth, V. P. (2019). Advances in Cutaneous Lupus Erythematosus and Dermatomyositis: A Report from the 4th International Conference on Cutaneous Lupus Erythematosus-An Ongoing Need for International Consensus and Collaborations. The Journal of investigative dermatology, 139(2), 270-276. PMID: 30243657.

Jabbari, A., Sansaricq, F., Cerise, J., Chen, J. C., Bitterman, A., Ulerio, G., Borbon, J., Clynes, R., Christiano, A. M. & Mackay-Wiggan, J. (2018). An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis. J Invest Dermatol, 138, 1539. PMID: 29452121.

Kennedy, C. M., Ko, J. M., Craiglow, B. G., Li, S., Shankar, G., Urban, J. R., Chen, J. C., Cerise, J. E., Jabbari, A., Winge, M. C., Marinkovich, M. P., Christiano, A. M., Oro, A. E. & King, B. A. (2016). Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata. JCI Insight, 1, e89776. PMID: 27699252.

Mackay-Wiggan*, J., Jabbari*, A., Nguyen, N., Cerise, J. E., Clark, C., Ulerio, G., Furniss, M., Vaughn, R., Christiano, A. M. & Clynes, R. (2016). Oral ruxolitinib induces hair regrowth in patients with moderate-to-severe alopecia areata. JCI Insight, 1, e89790. PMID: 27699253.

Dai, Z., Xing, L., Cerise, J., Wang, E. H., Jabbari, A., de Jong, A., Petukhova, L., Christiano, A. M. & Clynes, R. (2016). CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata. J Immunol, 197(4), 1089-99. PMID: 27412416.

Jabbari, A., Nguyen, N., Cerise, J. E., Ulerio, G., de Jong, A., Clynes, R., Christiano, A. M. & Mackay-Wiggan, J. (2016). Treatment of an alopecia areata patient with tofacitinib results in regrowth of hair and changes in serum and skin biomarkers. Exp Dermatol, 25(8), 642-3. PMID: 27119625.

Jabbari, A., Cerise, J. E., Chen, J. C., Mackay-Wiggan, J., Duvic, M., Price, V., Hordinsky, M., Norris, D., Clynes, R. & Christiano, A. M. (2016). Molecular signatures define alopecia areata subtypes and transcriptional biomarkers. EBioMedicine,(7), 240-7. PMID: 27322477.

Harris, J. E., Rashighi, M., Nguyen, N., Jabbari, A., Ulerio, G., Clynes, R., Christiano, A. M. & Mackay-Wiggan, J. (2016). Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA). J Am Acad Dermatol, 74(2), 370-1. PMID: 26685721.

Chen, J. C., Cerise, J. E., Jabbari, A., Clynes, R. & Christiano, A. M. (2015). Master regulators of infiltrate recruitment in autoimmune disease identified through network-based molecular deconvolution. Cell Syst, 1(5), 326-337. PMID: 26665180.

Chan, E. S., Herlitz, L. C. & Jabbari, A. (2015). Ruxolitinib attenuates cutaneous lupus development in a mouse lupus model. J invest Dermatol, 135(9), 2338-9. PMID: 26134782.

Jabbari, A., Dai, Z., Cerise, J. E., Ramot, Y., Berkun, Y., Sanchez, G. A., Goldbach-Mansky, R., Christiano, A. M., Clynes, R. & Zlotogorski, A. (2015). Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib. EbioMedicine, 2(4), 351-5. PMID: 26137574.

Xing*, L., Dai*, Z., Jabbari*, A., Cerise, J. E., Higgins, C. A., Gong, W., De Jong, A., Harel, S., DeStefano, G. M., Rothman, L., Singh, P., Petukhova, L., Mackay-Wiggan, J., Christiano, A. M. & Clynes, R. (2014). Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition. Nat Med, 20(9), 1043-9. PMID: 25129481.

Jabbari, A., Suarez-Farinas, M., Fuentes-Duculan, J., Gonzalez, J., Cueto, I., Franks Jr, A. G. & Krueger, J. G. (2014). Dominant Th1 and minimal Th17 skewing in discoid lupus revealed by transcriptomic comparison with psoriasis. J Invest Dermatol, 134(1), 87-95. PMID: 23771123.

Rothman, L. R., Levender, M. M., Scharf, M. D., Herman, S. P. & Jabbari, A. (2013). Iododerma following serial computed tomography scans in a lung cancer patient. J Drugs Dermatol, 12(5), 574-6. PMID: 23652954.

Jabbari, A., Petukhova, L., Cabral, R. M., Clynes, R. & Christiano, A. M. (2013). Genetic basis of alopecia areata: a roadmap for translational research. Dermatol Clin, 31(1), 109-17. PMID: 23159180.

Tian, S., Krueger, J. G., Li, K., Jabbari, A., Brodmerkel, C., Lowes, M. A. & Suarez-Farinas, M. (2012). Meta-analysis derived (MAD) transcriptome of psoriasis defines the "core" pathogenesis of disease. PLoS One, 7(9), e44274. PMID: 22957057.

Mandell, J. A., Tlougan, B. E., Jabbari, A., Walters, R. F. & Kundu, R. V. (2012). Erosive plaques on the dorsal surfaces of the hands. JAAD, 66(2), e31-32. DOI: http://dx.doi.org/10.1016/j.jaad.2011.02.027.

Jabbari, A., Suarez-Farinas, M., Dewell, S. & Krueger, J. G. (2012). Transcriptional profiling of psoriasis using RNA-seq reveals previously unidentified differentially expressed genes. J Invest Dermatol, 131(1), 246-249. PMID: 21850022.

Jabbari, A., Levine, V. J. (2011). Ablative Resurfacing: Laser, Chemical Peels, and Dermabrasion. In M. Alam (Eds.) Evidence-Based Procedural Dermatology. pp. 257-270. New York, NY: Springer Science+Business Media LLC.

Jabbari, A., Johnson-Huang, L. M. & Krueger, J. G. (2011). Role of the immune system and immunological circuits in psoriasis. G Ital Dermatol Venereol, 146(1), 17-30. PMID: 21317854.

Jabbari, A., Ralston, J. & Schaffer, J. V. (2010). Incontinentia pigmenti. Dermatol Online, 16(11), 9. PMID: 21163160.

Gonzalez, M. E., Jabbari, A., Tlougan, B. E., Mandal, R. & Schaffer, J. V. (2010). Epidermal Nevus. Dermatol Online, 16(11), 12. PMID: 21163163.

Jabbari, J. A., Gonzalez, M. E., Franks Jr, A. G. & Sanchez, M. (2010). Laugier Hunziker syndrome. Dermatol Online J, 16(11), 23. PMID: 21163174.

Jabbari, A., Cheung, W., Kamino, H. & Soter, N. A. (2009). Interstitial granulomatous dermatitis with arthritis. Dermatol Online, 15(8), 22. PMID: 19891930.

Messingham, K. A., Badovinac, V. P., Jabbari, A. & Harty, J. T. (2007). A role for IFN-gamma from antigen-specific CD8+ T cells in protective immunity to Listeria monocytogenes. J Immunol, 179(4), 2457-66. PMID: 17675507.

Jabbari, A., Legge, K. L. & Harty, J. T. (2006). T cell conditioning explains early disappearance of the memory CD8 T cell response to infection. J Immunol, 177(5), 3012-8. PMID: 16920937.

Jabbari, A., Harty, J. T. (2006). The generation and modulation of antigen-specific memory CD8 T cell responses. J Leukoc Biol, 80(1), 16-23. PMID: 16684891.

Jabbari, A., Harty, J. T. (2006). Simultaneous assessment of antigen-stimulated cytokine production and memory subset composition of memory CD8 T cells. J immunol Methods, 313(1-2), 161-8. PMID: 16762359.

Jabbari, A., Harty, J. T. (2006). Secondary memory CD8+ T cells are more protective but slower to acquire a central-memory phentype. J Exp Med, 203(4), 919-32. PMID: 16567385.

Jabbari, A., Harty, J. T. (2005). Cutting edge: differential self-peptide/MHC requirement for maintaining CD8 T cell function versus homeostatic proliferation. J Immunol, 175(8), 4829-33. PMID: 16210583.

Badovinac, V. P., Messingham, K. A., Jabbari, A., Haring, J. S. & Harty, J. T. (2005). Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination. Nat Med, 11(7), 748-56. PMID: 15951824.