Mark A. Greiner, MD

Portrait
Medical Director, Iowa Lions Eye Bank
Robert and Joell Brightfelt Professor of Cornea Research
Associate Professor of Ophthalmology and Visual Sciences

Contact Information

Staff Contact
11290-A PFP
200 Hawkins Drive
Iowa City, IA 52242
319-356-2861

Staff Contact
319-356-2861

Education

BA, English, University of California, Berkeley
MD, Medicine, University of California, Davis School of Medicine
Internship, University of California, Davis Medical Center, Internal Medicine
Resident, Ophthalmology Resident, University of California, Davis Health System Eye Center
Cornea, Clinical Fellowship, Devers Eye Institute

Licensure and Certifications

ABO diplomate - American Board of Ophthalmology

Center, Program and Institute Affiliations

Fraternal Order of Eagles Diabetes Research Center, Institute for Vision Research

Publications

Wagoner, M. D., Bohrer, L. R., Aldrich, B. T., Greiner, M. A., Mullins, R. F., Worthington, K. S., Tucker, B. A. & Wiley, L. A. (2018). Feeder-free differentiation of cells exhibiting characteristics of corneal endothelium from human induced pluripotent stem cells. Biology open, 7(5). PMID: 29685994.

Chahal, H. S., Estrada, M., Sindt, C. W., Boehme, J. A., Greiner, M. A., Nerad, J. A., Carter, K. D., Allen, R. C. & Shriver, E. M. (2018). Scleral Contact Lenses in an Academic Oculoplastics Clinic: Epidemiology and Emerging Considerations. Ophthalmic plastic and reconstructive surgery, 34(3), 231-236. PMID: 28538612.

Skeie, J. M., Aldrich, B. T., Goldstein, A. S., Schmidt, G. A., Reed, C. R. & Greiner, M. A. (2018). Proteomic analysis of corneal endothelial cell-descemet membrane tissues reveals influence of insulin dependence and disease severity in type 2 diabetes mellitus. PloS one, 13(3), e0192287. PMID: 29529022.

Greenwald, M. F., Niles, P. I., Johnson, A. T., Vislisel, J. M. & Greiner, M. A. (2018). Descemet membrane endothelial keratoplasty for corneal decompensation due to iridoschisis. American journal of ophthalmology case reports, 9, 34-37. PMID: 29468215.

Lass, J. H., Benetz, B. A., Verdier, D. D., Szczotka-Flynn, L. B., Ayala, A. R., Liang, W., Aldave, A. J., Dunn, S. P., McCall, T., Mian, S. I., Navarro, L. C., Patel, S. V., Pramanik, S., Rosenwasser, G. O., Ross, K. W., Terry, M. A., Kollman, C., Gal, R. L. & Beck, R. W. (2017). Corneal Endothelial Cell Loss 3 Years After Successful Descemet Stripping Automated Endothelial Keratoplasty in the Cornea Preservation Time Study: A Randomized Clinical Trial. JAMA ophthalmology, 135(12), 1394-1400. PMID: 29127432.

Rosenwasser, G. O., Szczotka-Flynn, L. B., Ayala, A. R., Liang, W., Aldave, A. J., Dunn, S. P., McCall, T., Navarro, L. C., Pramanik, S., Ross, K. W., Stulting, R. D., Terry, M. A., Tu, E. Y., Verdier, D. D., Kollman, C., Gal, R. L., Beck, R. W. & Lass, J. H. (2017). Effect of Cornea Preservation Time on Success of Descemet Stripping Automated Endothelial Keratoplasty: A Randomized Clinical Trial. JAMA ophthalmology, 135(12), 1401-1409. PMID: 29127431.

Janson, B. J., Alward, W. L., Kwon, Y. H., Bettis, D. I., Fingert, J. H., Provencher, L. M., Goins, K. M., Wagoner, M. D. & Greiner, M. A. (In Press). Glaucoma-associated corneal endothelial cell damage: A review. Survey of ophthalmology. PMID: 29146208.

Greiner, M. A., Terveen, D. C., Vislisel, J. M., Roos, B. R. & Fingert, J. H. (2017). Assessment of a three-generation pedigree with Fuchs endothelial corneal dystrophy with anticipation for expansion of the triplet repeat in the TCF4 gene. Eye (London, England), 31(8), 1250-1252. PMID: 28387761.

Chung, A. T., Lenci, L. T., Wang, K., Collins, T. E., Griess, M. D., Oetting, T. A. & Shriver, E. M. (2017). Effect of fine-motor-skill activities on surgical simulator performance. Journal of cataract and refractive surgery, 43(7), 915-922. PMID: 28823438.

Liaboe, C. A., Aldrich, B. T., Carter, P. C., Skeie, J. M., Burckart, K. A., Schmidt, G. A., Reed, C. R., Zimmerman, M. B. & Greiner, M. A. (2017). Assessing the Impact of Diabetes Mellitus on Donor Corneal Endothelial Cell Density. Cornea, 36(5), 561-566. PMID: 28306601.

Aldrich, B. T., Schlötzer-Schrehardt, U., Skeie, J. M., Burckart, K. A., Schmidt, G. A., Reed, C. R., Zimmerman, M. B., Kruse, F. E. & Greiner, M. A. (2017). Mitochondrial and Morphologic Alterations in Native Human Corneal Endothelial Cells Associated With Diabetes Mellitus. Investigative ophthalmology & visual science, 58(4), 2130-2138. PMID: 28395029.

Vislisel, J. M., Goins, K. M., Wagoner, M. D., Schmidt, G. A., Aldrich, B. T., Skeie, J. M., Reed, C. R., Zimmerman, M. B. & Greiner, M. A. (2017). Incidence and Outcomes of Positive Donor Corneoscleral Rim Fungal Cultures after Keratoplasty. Ophthalmology, 124(1), 36-42. PMID: 27817919.

Schwarz, C., Aldrich, B. T., Burckart, K. A., Schmidt, G. A., Zimmerman, M. B., Reed, C. R., Greiner, M. A. & Sander, E. A. (2016). Descemet membrane adhesion strength is greater in diabetics with advanced disease compared to healthy donor corneas. Experimental eye research, 153, 152-158. PMID: 27777123.

Blitvich, B. J., Wang, T., Saxena, V., Zeng, S., Harmon, K. M., Raymond, M. D., Goins, K. M., Reed, C. R., Mullins, R. F. & Greiner, M. A. (2016). West Nile Virus Infection in Human and Mouse Cornea Tissue. The American journal of tropical medicine and hygiene, 95(5), 1185-1191. PMID: 27672204.

Goins, K. M., Kitzmann, A. S., Greiner, M. A., Kwon, Y. H., Alward, W. L., Ledolter, J. & Wagoner, M. D. (2016). Boston Type 1 Keratoprosthesis: Visual Outcomes, Device Retention, and Complications. Cornea, 35(9), 1165-74. PMID: 27191675.

Flanary, W. E., Vislisel, J. M., Wagoner, M. D., Raecker, M. E., Aldrich, B. T., Zimmerman, M. B., Goins, K. M. & Greiner, M. A. (2016). Incidence of Cystoid Macular Edema After Descemet Membrane Endothelial Keratoplasty as a Staged and Solitary Procedure. Cornea, 35(8), 1040-4. PMID: 27158809.

Hager, J. L., Phillips, D. L., Goins, K. M., Kitzmann, A. S., Greiner, M. A., Cohen, A. W., Welder, J. D. & Wagoner, M. D. (2016). Boston type 1 keratoprosthesis for failed keratoplasty. International ophthalmology, 36(1), 73-8. PMID: 25975459.

Haugsdal, J. M., Goins, K. M., Greiner, M. A., Kwon, Y. H., Alward, W. L. & Wagoner, M. D. (2016). Boston type 1 keratoprosthesis for primary congenital glaucoma. British Journal of Ophthalmology, 100(3), 328-31. PMID: 26206789.

Wagoner, M. D., Welder, J. D., Goins, K. M. & Greiner, M. A. (2016). Microbial Keratitis and Endophthalmitis After the Boston Type 1 Keratoprosthesis. Cornea, 35(4), 486-93. PMID: 26764885.

Aldrich, B. T., Stockman, A. M., Freiburger, M. J., Shinkunas, T. J., Burckart, K. A., Schmidt, G. A., Reed, C. R., Zimmerman, M. B., Goins, K. M., Wagoner, M. D. & Greiner, M. A. (2015). A Simple and Reliable Technique to Orient Donor Corneal Tissue Using the Radial Width of the Surgical Limbus. Cornea, 34(12), 1632-6. PMID: 26488631.

Phillips, D. L., Goins, K. M., Greiner, M. A., Alward, W. L., Kwon, Y. H. & Wagoner, M. D. (2015). Boston Type 1 Keratoprosthesis for Iridocorneal Endothelial Syndromes. Cornea, 34(11), 1383-1386. DOI: 10.1097/ico.0000000000000616.

Donaghy, C. L., Vislisel, J. M., Greiner, M. A., M, G. K. & D, W. M. (2015). Calcific Band Keratopathy. EyeRounds.org.

Vislisel, J. M., Liaboe, C. A., Wagoner, M. D., Goins, K. M., Sutphin, J. E., Schmidt, G. A., Zimmerman, M. B. & Greiner, M. A. (2015). Graft survival of diabetic versus nondiabetic donor tissue after initial keratoplasty. Cornea, 34(4), 370-4. PMID: 25642643.

Greiner, M. A., Burckart, K. A., Wagoner, M. D., Schmidt, G. A., Reed, C. R., Liaboe, C. A., Flamme-Wiese, M. J., Zimmerman, M. B., Mullins, R. F., Kardon, R. H., Goins, K. M. & Aldrich, B. T. (2015). Regional assessment of energy-producing metabolic activity in the endothelium of donor corneas. Investigative Ophthalmology and Visual Science, 56(5), 2803-2810. PMID: 26024071.

Sacher, B. A., Wagoner, M. D., Goins, K. M., Sutphin, J. E., Greiner, M. A. & Kitzmann, A. S. (2015). Treatment of acanthamoeba keratitis with intravenous pentamidine before therapeutic keratoplasty. Cornea, 34(1), 49-53. PMID: 25255139.

Greiner, M. A., Rixen, J. J., Wagoner, M. D., Schmidt, G. A., Stoeger, C. G., Straiko, M. D., Zimmerman, M. B., Kitzmann, A. S. & Goins, K. M. (2014). Diabetes mellitus increases risk of unsuccessful graft preparation in Descemet membrane endothelial keratoplasty: a multicenter study. Cornea, 33(11), 1129-33. PMID: 25222000.

Brown, C. R., Wagoner, M. D., Welder, J. D., Cohen, A. W., Goins, K. M., Greiner, M. A. & Kitzmann, A. S. (2014). Boston Keratoprosthesis Type 1 for Herpes Simplex and Herpes Zoster Keratopathy. Cornea, 33(8), 801-05. PMID: 24932767.

Phillips, D. L., Hager, J. L., Goins, K. M., Kitzmann, A. S., Greiner, M. A., Cohen, A. W., Welder, J. D. & Wagoner, M. D. (2014). Boston type 1 keratoprosthesis for chemical and thermal injury. Cornea, 33(9), 905-909. PMID: 25055151.

Greiner, M. A., Straiko, M. D. & Terry, M. A. (2014). Endothelial Keratoplasty and Anterior Segment Optical Coherence Tomography. In Spectral Domain OCT of the Eye: The A to Z Clinical Atlas. Mumbai: Elsevier India.

Ward, M. S., Goins, K. M., Greiner, M. A., Kitzmann, A. S., Sutphin, J. E., Alward, W. L., Greenlee, E. C., Kwon, Y. H., Zimmerman, M. B. & Wagoner, M. D. (2014). Graft Survival Versus Glaucoma Treatment After Penetrating or Descemet Stripping Automated Endothelial Keratoplasty. Cornea, 33(8), 785-89. PMID: 24915017.

Tandon, A., Tehrani, S., Greiner, M. A., Fingert, J. H. & Alward, W. L. (2014). Thin Central Corneal Thickness and Early-Onset Glaucoma in Lacrimo-auriculo-dento-digital Syndrome. JAMA Ophthalmol, 132(6), 782-84. PMID: 24921174.

Maltry, A. C., Greiner, M. A. (2013). Descemet’s membrane endothelial keratoplasty (DMEK) for Fuchs’ endothelial dystrophy. Eyerounds.org.

Davis-Boozer, D., Terry, M. A., Greiner, M. A., Holiman, J., Saad, H. A., Alqudah, A. A. & LI, J. Y. (2013). In vitro evaluation of endothelial cell loss using the neusidl corneal inserter. Cornea, 32(4), 479-82. PMID: 23187162.

Greiner, M. A., Li, J. Y. & Mannis, M. J. (2013). Boston Keratoprosthesis Complications. In E. J. Holland , M. J. Mannis & W. B. Lee (Eds.) Ocular Surface Disease: Cornea, Conjunctiva and Tear Film. pp. 421-426. London, UK: Elsevier.

Li, J. Y., Greiner, M. A. & Mannis, M. J. (2013). Boston Keratoprosthesis Outcomes. In E. J. Holland , M. J. Mannis & W. B. Lee (Eds.) Ocular Surface Disease: Cornea, Conjunctiva and Tear Film. pp. 413-420. London, UK: Elsevier.

Alqudah, A. A., Terry, M. A., Straiko, M. D., Greiner, M. A. & Davis-Boozer, D. (2013). Immediate endothelial cell loss after penetrating keratoplasty. Cornea, 32(12), 1587-90. PMID: 24145632.

Pangare, M., Makino, A. (2012). Mitochondrial function in vascular endothelial cell in diabetes. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 48(1), 1-26. PMID: 22504486.

LI, J. Y., Greiner, M. A., Brandt, J. D., Lim, M. C. & Mannis, M. J. (2011). Long-term complications associated with glaucoma drainage devices and Boston keratoprosthesis. American Journal of Ophthalmology, 152(2), 209-18. PMID: 21636070.

Greiner, M. A., Li, J. Y. & Mannis, M. J. (2011). Longer-term vision outcomes and complications with the Boston type 1 keratoprosthesis at the University of California, Davis. Ophthalmology, 118(8), 1543-50. PMID: 21397948.

Li, J. Y., Greiner, M. A., Brandt, J. D., Lim, M. C. & Mannis, M. J. (2011). Author's reply [Long-term complications associated with glaucoma drainage devices and Boston keratoprosthesis]. American Journal of Ophthalmology, 152(5), 884-5. PMID: 22017851.

Choi, S. D., Zawadzki, R. H., Greiner, M. A., Werner, J. S. & Keltner, J. L. (2008). Fourier-domain optical coherence tomography and adaptive optics reveal nerve fiber layer loss and photoreceptor changes in a patient with optic nerve drusen. Journal of Neuro-ophthalmology, 28(2), 120-5. PMID: 18562844.

Greiner, M., Nickerson, G. & Rosenberg, S. (2001). State policy context for school-based health centers. Health and Health Care in Schools website.