Logo for University of Iowa Health Care This logo represents the University of Iowa Health Care

Division of Endocrinology and Metabolism

The Division of Endocrinology and Metabolism is proud to be designated a Center of Excellence by the ENETs.

The University of Iowa Neuroendocrine Tumor Clinic is designated as a Center for Excellence by the Pheo Para Alliance

University of Iowa Health Care is listed among the “high performing” institutions in the nation and #1 in Iowa for its adult diabetes and endocrinology care.

Ayotunde Dokun, MD, PhD
Associate Professor and Director
Division of Endocrinology and Metabolism

The Division of Endocrinology and Metabolism is committed to providing excellent clinical care, education of learners at all levels, and the advancement of knowledge through pursuit of biomedical research. Clinical care is provided in the University of Iowa Hospitals and Clinics inpatient units and the Medicine Specialty Clinic. All division faculty members are board certified in endocrinology and are regionally and nationally recognized for their expertise. The faculty, in collaboration with nurse practitioners and specialized nursing staff such as certified diabetes educators, endocrine nurses, dietitians and social workers, are focused on the delivery of excellent clinical care.

Division News

  • Blocking ceramides with fungi extract reverses diabetes, obesity, in mice
    In a recent publication in Scientific Reports, Dr. Bhagirath Chaurasia demonstrates how an over-the-counter fungal extract has the potential to prevent and even reverse diabetes and its associated complications.

  • Dokun, national panel update diabetes care recommendations for US Congress
    Dr. Dokun served on the drafting panel of this report, which acknowledges the impact that social determinants of health have on diabetes prevention and management

  • UI Health Care designated first Pheo Para Cancer Center of Excellence in Iowa and surrounding states
    Pheo Para Alliance has designated UI Health Care as a Center of Excellence for pediatric and adult cancers, the first designation made in Iowa and the surrounding states.

  • Recent pulication: Insulin and IGF-1 receptors regulate complex-I dependent mitochondrial bioenergetics and supercomplexes via FoxOs in muscle.  Bhardwaj G, Penniman CM, Jena J, Suarez Beltran PA, Foster C, Poro K, Junck TL, Hinton AO Jr, Souvenir R, Fuqua JD, Morales PE, Bravo-Sagua R, Sivitz WI, Lira VA, Abel ED, O'Neill BT. J Clin Invest. 2021 Aug 3:146415.

  • Recent publication: Altering Early Life Gut Microbiota Has Long-Term Effect on Immune System and Hypertension in Spontaneously Hypertensive Rats. Francois M. Abboud, Michael Z. Cicha, Aaron Ericsson, Mark W. Chapleau, and Madhu V. Singh. Front. Physiol., 29 October 2021.

  • Recent publication: Efflux of Citrate and Isocitrate Is Fully Dispensable for Glucose-Stimulated Insulin Secretion and Pancreatic Islet β-Cell Function. Casey J Bauchle, Kristen E Rohli, Cierra K Boyer, Vidhant Pal, Jonathan V Rocheleau, Siming Liu, Yumi Imai, Eric B Taylor, Samuel B Stephens. Journal: Diabetes. 2021 Aug;70(8):1717-1728

  • Celebrating the many successes of endocrinologys members
    Members of the Division of Endocrinology and Metabolism gathered in Division Director Dr. Ayotunde Dokun’s backyard to celebrate a number of recent successes.

  • Links between type 2 diabetes and lipid mobilization point to new treatment target
    Yumi Imai, MD, associate professor in Endocrinology and Metabolism, received a four-year, $710,000 VA Merit Award. With this new grant, Imai will build on previous research to investigate type 2 diabetes treatment by identifying correlations between lipolysis and beta cell dysfunction.

  • Congratulations to 2020-2021 Service Award Receipients Bianca Carlson, PA-C, Melissa Collier, ARNP, and Sarah Nolan, PA-C!

  • Sivitz awarded $1.26M to continue study of brown fat (June 15, 2021)
    Dr. William Sivitz received a four-year, $1.26M grant from the Natinal Institute fir Diabetes and Digestive Kidney Diseases to examine the metabolic contral of the citrif acid cycle in brow fat.

  • Dokun publication selected as a feature article in Experimental Biology and Medicine
    Congratualtions to Dr. Dokun and his team for their recent article entitled “Inhibition of PKCβ phosphorylation activates NF-κB and improves post-ischemic recovery in type 1 diabetes,” which has been selected as a feature article in EBM.

  • Pereira investigates brown fat cell role in combating obesity (December 15, 2020)
    Dr. Renata Pereira Alambert has receivd a five-year $1.93M R01 grant from the NIH to investigate methods to increase metabolism in brown fat cells. She proposes to invenstigate whether GDF15 promotes leanness in mice deficient for OPA1.

  • Hinton Selected as Ernest E. Just Postgraduate Fellow (April 7, 2020)
    Antentor (AJ) Hinton, Jr., PhD has been named an E.E. Just Postgraduate Fellow in the Life Sciences by the The United Negro College Fund. This fellowship is aimed at accelerating the career development of African Americans pursuing research careers in academic settings or biopharmaceutical companies. Hinton will receive a large stipend, a research budget, travel funds, and access to mentors andprofessional networks.

  • Stephens receives CDMRP grant (March 23, 2020)
    Sam Stephens, PhD has received a $1.2 million grant awarded by the Congressionally Direct Medical Research Program (CDMRP), administered by the Department of Defense for diabetes research. Stephens’ research project “Exhausted Protein Sorting Capacity Impairs Beta-Cell Function in Type 2 Diabetes” will focus on examining how defects in insulin synthesis and packaging within the pancreatic islet beta-cell contributes to beta-cell dysfunction in T2D. The funds will be awarded in $400,000 increments over a three year period.

  • Yorek Pub Lands on the Wall
    Congratulations to Mark A. Yorek, PhD, for his 2020 induction to the Wall of Scholarship for his publication “Membrane lipid composition and cellular function.” Journal of Lipid Research. 1985 Sep;26(9):1015-35. The Carver College of Medicine Wall of Scholarship recognizes published research articles of current faculty that have been cited over 1,000 times in subsequent published research articles.

  • Nolan receives Endocrine Division Service Award (February 18, 2020)
    In recognition of her five years of excellence, dedication, and contributions to the care of our patients and to the division’s success, the Division of Endocrinology and Metabolism paused recently to award Sarah Nolan, PA-C, with her Service Award. Nolan has been instrumental in the tremendous growth of the inpatient diabetes service and her leadership and diligence have led to major improvements in clinical outcomes. The Division also recognized the exceptional mentorship and training that Amal Shibli-Rahhal, MD, MS, and Janet Schlechte, MD, have provided Nolan along the way.

  • Nolan, Collier Promote Provider Communication Program (February 11, 2020)
    Sara Nolan, PA, and Melissa Collier, ARNP recently participated in the UI Health Care-sponsored Provider Communication Program. The program helped them hone their skills and achieve more effective interactions with patients. The Provider Communication Program is available to all physicians, APPs, PAs, and ARNPs within UI Health Care. Sign up today!

  • Rahmouni and Abel named co-directors of the Obesity Research and Education Initiative
    January 31, 2020 - The UI Carver College of Medicine has announced the appointment of Kamal Rahmouni, PhD, and Dale Abel, MD, PhD, as co-directors of the Obesity Research and Education Initiative.

  • Abel to lead one of four AHA research networks (December 16, 2019)

  • Diabetes research enters "the matrix" (November 13, 2019)
    Work being done within the Fraternal Order of Eagles Diabetes Research Center (FOEDRC) will be featured in an episode titled “Reversing Diabetes”on the program Information Matrix, hosted by Laurence Fishburne.

  • Endocrinology aids in SSI reduction project (November 5, 2019)
    PA Sarah Nolan and Melissa Collier, RN, are two members of a working group within University of Iowa Health Care designed to lower the incidence of surgical site infections. By focusing on people at risk of hyperglycemia and strictly monitoring their blood glucose levels, the two and the rest of the group comprised of members from eight different departments, have successfully prevented all incidences of hyperglycemia and lowered SSIs in patients undergoing colon and cardiothoracic surgery by 40 percent.

  • At the Forefront: Diabetes care at UI Hospitals and Clinics

  • How diabetes harms the heart
    Study in mice reveals heart-damaging pathway triggered by insulin, identifies possible drug targets to prevent or treat heart failure.

Jobs at the University of Iowa: The Academic Difference

Endocrinology Faculty Members
Positions at the rank of Professor on either the clinical or tenure track.  Duties will include inpatient consults at University of Iowa Hospitals and Clinics (UIHC) and outpatient clinics at UIHC and Iowa River Landing (IRL).