Chou-Long Huang, MD, PhD
Professor of Internal Medicine-Nephrology
Current Positions
- Professor of Internal Medicine-Nephrology
Education
- MD, Taipei Medical University, Taipei, Taiwan
- PhD, Physiology, University of California San Francisco, San Francisco, California
- Postdoctoral Fellow, Cardiovascular Research, University of California San Francisco, San Francisco, California
- Resident, Internal Medicine, University of Iowa Hospitals & Clinics, Iowa City, Iowa
- Fellow, Nephrology, University of California San Francisco, San Francisco, California
- Postdoctoral Fellow, Howard Hughes Medical Institute, University of California San Francisco, San Francisco, California
Graduate Program Affiliations
Selected Publications
- Chi, R., Wang, T., Huang, C., Wu, S., Young, S. L., Lydon, J. P. & DeMayo, F. J. (2020).
WNK1 regulates uterine homeostasis and its ability to support pregnancy. JCI Insight 5 (22). DOI: https://doi.org/10.1172/jci.insight.141832. - Sie, Z. L., Li, R. Y., Sampurna, B. P., Hsu, P. J., Liu, S. C., Wang, H. D., Huang, C. L. & Yuh, C. H. (2020). WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis. Cancers 12 (3). DOI: 10.3390/cancers12030575. PMID: 32131390.
- Huang, C. L., Jian, X. & Yuh, C. H. (2020). WNK1-OSR1/SPAK KINASE CASCADE IS IMPORTANT FOR ANGIOGENESIS. Transactions of the American Clinical and Climatological Association 131 140-146. PMID: 32675854. PMCID: PMC7358493.
- Chen, J., Lin, S., Huang, C. & Cheng, C. (2019). Reply to Farfel et al.: Is enhanced chloride reabsorption in proximal tubule a possible mechanism of metabolic acidosis I PHAII?. Proc. Natl. Acad. Sci. USA 116 16175-16176.
- Yang, Y. S., Xie, J., Yang, S. S., Lin, S. H. & Huang, C. L. (2018). Differential roles of WNK4 in regulation of NCC in vivo. American journal of physiology. Renal physiology 314 (5) F999-F1007. DOI: 10.1152/ajprenal.00177.2017. PMID: 29384416. PMCID: PMC6031911.
- Boyd-Shiwarski, C. R., Shiwarski, D. J., Roy, A., Namboodiri, H. N., Nkashama, L. J., Xie, J., McClain, K. L., Marciszyn, A., Kleyman, T. R., Tan, R. J., Stolz, D. B., Puthenveedu, M. A., Huang, C. L. & Subramanya, A. R. (2018). Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent. Molecular biology of the cell 29 (4) 499-509. DOI: 10.1091/mbc.E17-08-0529. PMID: 29237822. PMCID: PMC6014176.
- Cheng, C., Rodan, A. R. & Huang, C. (2017). Emerging targets of diuretic therapy. Clin Pharmacol Ther. DOI: 10.1002/cpt.754.
- Wright, J. D., An, S. W., Xie, J., Yoon, J., Nischan, N., Kohler, J. J., Oliver, N., Lim, C. & Huang, C. L. (2017). Modeled structural basis for the recognition of α2-3-sialyllactose by soluble Klotho. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. DOI: 10.1096/fj.201700043R. PMID: 28442546.
- Wu, Y. L., Xie, J., An, S. W., Oliver, N., Barrezueta, N. X., Lin, M. H., Birnbaumer, L. & Huang, C. L. (2017). Inhibition of TRPC6 channels ameliorates renal fibrosis and contributes to renal protection by soluble klotho. Kidney international 91 (4) 830-841. DOI: 10.1016/j.kint.2016.09.039. PMID: 27979597. PMCID: PMC5357448.
- Dalton, G., An, S., Al-Juboori, S. I., Nischan, N., Yoon, J., Dobrinskikh, E., Hilgemann, D. W., Xie, J., Luby-Phelps, K., Kohler, J. J., Birnbaumer, L. & Huang, C. (2017). Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 114 (4) 752-757. DOI: 10.1073/pnas.1620301114.