Haider Mehdi, PhD

Research Assistant Professor of Internal Medicine - Cardiovascular Medicine


PhD, Biochemistry, AM University/CDRI, Aligarh, UP India
Postdoctoral Fellow, Rush-Presbyterian-St. Lukes Medical Center

Research Summary

Dr. Haider Mehdi’s research interests include genetics of common diseases of public health with special emphasis on cardiovascular disease. Over the past several years, Dr. Mehdi has been instrumental in identifying and characterizing a candidate gene, glycerol-3-phosphate dehydrogenase 1-like (GPD1-L), for Brugada syndrome (BrS), an inherited arrhythmia disorder. Dr. Mehdi has then developed a mouse model for BrS by knocking down GPD1-L which mimicked the Brugada phenotype. In addition to this, his other focus of research is to elucidate the mechanism by which the post-translational modification (may be some novel one?) affects the membrane-trafficking and function of cardiac sodium channel (Nav1.5, SCN5A).