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Jason Barker, MD

Associate Professor of Internal Medicine-Infectious Diseases

Current Positions

  • Associate Professor of Internal Medicine-Infectious Diseases

Education

  • MD, Baylor College of Medicine, Houston, Texas
  • Resident, Internal Medicine, University of Texas Southwestern, Dallas, Texas
  • Fellow, Infectious Diseases, University of Iowa Hospitals & Clinics, Iowa City, Iowa

Center, Program and Institute Affiliations

Selected Publications

  • Kobayashi, T., Amram, A. L., Gehrs, K., Diekema, D. & Barker, J. H. (2021). A 52 year old man with uveitis and altered mental status. Clinical Infectious Diseases 72 (5) 873-875. DOI: 10.1093/cid/ciaa051.
  • Russo, T. A., Olson, R., Fang, C., Stoesser, N., Miller, M., MacDonald, U., Hutson, A., Barker, J. H., La Hoz, R. M., Johnson, J. R. & (2019). Identification of Biomarkers for Differentiation of Hypervirulent Klebsiella pneumoniae from Classical K. pneumoniae. J Clin Microbiol 56 (9) e00776-18. PMCID: PMC6113484.
  • Barker, J. H. & Weiss, J. P. (2019). Detecting lipopolysaccharide in the cytosol of mammalian cells: Lessons from MD-2/TLR4. Journal of Leukocyte Biology 106 (1) 127-132. PMID: 30694581.
  • Weiss, J. & Barker, J. H. (2018). Diverse pro-inflammatory endotoxin recognition systems of mammalian innate immunity. F1000Research 7 516. DOI: 10.12688/f1000research.13977.1.
  • Kinkead, L., Whitmore, L., McCracken, J., Fletcher, J., Ketelsen, B., Kaufman, J., Weiss, D., Barker, J. H. & Allen, L. H. (2018). Bacterial lipoproteins and other factors released by Francisella tularensis modulate human neutrophil lifespan: effects of a TLR1 SNP on apoptosis inhibition. Cellular Microbiology.
  • Wacker, M. A., Teghanemt, A., Weiss, J. P. & Barker, J. H. (2017). High Affinity Caspase-4 Binding to Lipopolysaccharide Presented as High Molecular Weight Aggregates or in Outer Membrane Vesicles. Innate Immunity 23 (4) 336-344. PMCID: PMC5540323.
  • Barker, J. H., Kaufman, J. W., Apicella, M. A. & Weiss, J. P. (2016). Evidence Suggesting That Francisella tularensis O-Antigen Capsule Contains a Lipid A-Like Molecule That Is Structurally Distinct from the More Abundant Free Lipid A. (Vols. 11). pp. e0157842. San Francisco, California: PLoS One. PMCID: PMC4915664.
  • Barker, J. H., Kaufman, J. W., Zhang, D. S. & Weiss, J. P. (2014). Metabolic labeling to characterize the overall composition of Francisella Lipid A and LPS grown in broth and in human phagocytes. Innate immunity 20 (1) 88-103. PMCID: PMC3796033.
  • Yao, C., Dixit, U. G., Barker, J. H., Teesch, L., Love-Homan, L., Donelson, J. & Wilson, M. E. (2013). Attenuation of Leishmania metacyclic promastigotes by sterol depletion. Infection and Immunity 81 (7) 2507-17. PMCID: PMC3697599.
  • Schwartz, J. T., Barker, J. H., Long, M. E., Kaufman, J., McCracken, J. & Allen, L. A. (2012). Natural IgM mediates complement-dependent uptake of Francisella tularensis by human neutrophils via complement receptors 1 and 3 in nonimmune serum. Journal of immunology (Baltimore, Md. : 1950) 189 (6) 3064-77. PMCID: PMC3436988.