Logo for University of Iowa Health Care This logo represents the University of Iowa Health Care

Jeffery L. Meier, MD

Associate Professor of Internal Medicine - Infectious Diseases

Contact Information

Primary Office
C327 GH
Iowa City, IA 52242


MD, University of Iowa
Resident, Internal Medicine, University of Wisconsin Hospital & Clinics, Madison, Wisconsin
Fellow, Infectious Diseases, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Laboratory of Clinical Investigation, Bethesda, Maryland

Licensure and Certifications

Infectious Diseases - American Board of Internal Medicine
Medical License - Iowa Board of Medicine
Internal Medicine - American Board of Internal Medicine

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Molecular Medicine

Research Summary

Dr. Meier's research interests are in human immunodeficiency virus and cytomegalovirus infections. He directs the University of Iowa HIV Clinical Trials Program. His laboratory studies human cytomegalovirus, with particular attention to the molecular mechanisms underlying viral replication, persistence, and reactivation and to the functioning of these mechanisms in different types of human cells and tissues. Cytomegalovirus is the most common infectious cause of birth defects and reactivates to cause life-threatening disease in persons with impaired immunity, such as persons having AIDS or receiving a stem cell or solid organ transplantation. Projects that are currently active in the laboratory include: 1) Characterization of the molecular pathways involved in silencing the human cytomegalovirus major immediate-early enhancer/promoter, the master control switch for viral replication. 2) Determination of the stimuli and signaling pathways involved in human cytomegalovirus reactivation in quiescently infected cells. 3) Characterization of human cytomegalovirus infection in neutrophils, macrophages, dendritic cells, and vascular tissues. 4) Evaluation of the role of human adipose tissue in cytomegalovirus dissemination and disease.