Mark W. Chapleau, PhD

Portrait
Professor of Internal Medicine - Cardiovascular Medicine
Professor of Molecular Physiology and Biophysics

Contact Information

Primary Office: 629 MRC
Iowa City, IA 52242
319-335-8958

Education

BS, Biology/Chemistry, University of Wisconsin
PhD, Physiology, Louisiana State University Medical Center

Post Doctoral Fellow, Research, University of Iowa College of Medicine

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Neuroscience

Center, Program and Institute Affiliations

Cardiovascular Research Center, George M. O’Brien Kidney Research Center

Research Summary

Dr. Chapleau's research focuses on mechanisms of autonomic regulation in health and disease including effects of aging, hypertension, hypercholesterolemia, cardiomyopathy, myocardial infarction (MI), heart failure, and muscular dystrophy. Key hypotheses involve the roles of acid-sensing ion channels in sensory transduction, reactive oxygen species and angiotensin in sensory and sympathetic signaling, and oxidative stress in autonomic dysregulation. Experimental approaches include assessment of the cellular and molecular basis of sensory transduction and neuronal excitability in baroreceptor and sympathetic neurons using patch-clamp, imaging, and molecular techniques; recording of baroreceptor and sympathetic nerve activity in vivo; and assessment of cardiovascular and autonomic function in conscious mice using radiotelemetry.

Publications

Chapleau, M. W., Rotella, D. L., Reho, J. J., Rahmouni, K. & Stauss, H. M. (2016). Chronic vagal nerve stimulation prevents high-salt diet-induced endothelial dysfunction and aortic stiffening in stroke-prone spontaneously hypertensive rats. American journal of physiology. Heart and circulatory physiology, 311(1), H276-85. PMID: 27208157.

Chu, Y., Lund, D. D., Doshi, H., Keen, H. L., Knudtson, K. L., Funk, N. D., Shao, J. Q., Cheng, J., Hajj, G. P., Zimmerman, K. A., Davis, M. K., Brooks, R. M., Chapleau, M. W., Sigmund, C. D., Weiss, R. M. & Heistad, D. D. (2016). Fibrotic Aortic Valve Stenosis in Hypercholesterolemic/Hypertensive Mice. Arterioscler Thromb Vasc Biol. DOI: 10.1161/atvbaha.115.306912.

Sabharwal, R., Rasmussen, L., Sluka, K. A. & Chapleau, M. W. (2016). Exercise prevents development of autonomic dysregulation and hyperalgesia in a mouse model of chronic muscle pain. Pain, 157(2), 387-98. DOI: 10.1097/j.pain.0000000000000330.

Prasad, A. M., Morgan, D. A., Nuno, D. W., Ketsawatsomkron, P., Bair, T. B., Venema, A. N., Dibbern, M. E., Kutschke, W. J., Weiss, R. M., Lamping, K. G., Chapleau, M. W., Sigmund, C. D., Rahmouni, K. & Grumbach, I. M. (2015). Calcium/calmodulin-dependent kinase II inhibition in smooth muscle reduces angiotensin II-induced hypertension by controlling aortic remodeling and baroreceptor function. J Am Heart Assoc, 4(6), e001949. DOI: 10.1161/jaha.115.001949.

Singh, M. V., Cicha, M. Z., Meyerholz, D. K., Chapleau, M. W. & Abboud, F. M. (2015). Dual Activation of TRIF and MyD88 Adaptor Proteins by Angiotensin II Evokes Opposing Effects on Pressure, Cardiac Hypertrophy, and Inflammatory Gene Expression. Hypertension, 66(3), 647-56. DOI: 10.1161/hypertensionaha.115.06011.

Sabharwal, R., Weiss, R. M., Zimmerman, K., Domenig, O., Cicha, M. Z. & Chapleau, M. W. (2015). Angiotensin-dependent autonomic dysregulation precedes dilated cardiomyopathy in a mouse model of muscular dystrophy. Experimental Physiology. DOI: 10.1113/EP085066.

Santana-Filho, V. J., Davis, G. J., Castania, J. A., Ma, X., Salgado, H. C., Abboud, F. M., Fazan, R. & Chapleau, M. W. (2014). Autocrine/paracrine modulation of baroreceptor activity after antidromic stimulation of aortic depressor nerve in vivo. (Vols. 180). pp. 24-31. Autonomic Neuroscience.

Raven, P. B., Chapleau, M. W. (2014). Blood pressure regulation XI: overview and future research directions. Eur J Appl Physiol, 114(3), 579-86. DOI: 10.1007/s00421-014-2823-z.

Chapleau, M. W. (2014). Contributions of skeletal muscle myopathy to heart failure: novel mechanisms and therapies. Introduction. Exp Physiol, 99(4), 607-8. DOI: 10.1113/expphysiol.2013.074294.

Sabharwal, R., Cicha, M. Z., Sinsterra, R. D., de Sousa, F. B., Santos, R. A. & Chapleau, M. W. (2014). Chronic oral administration of Ang-(1-7) improves skeletal muscle, autonomic and locomotor phenotypes in muscular dystrophy. (Vols. 127). pp. 101-109. Clinical Science (London). DOI: 10.1042/CS20130602.

Singh, M. V., Chapleau, M. W., Harwani, S. C. & Abboud, F. M. (2014). The immune system and hypertension. Immunol Res, 59(1-3), 243-53. DOI: 10.1007/s12026-014-8548-6.

Sabharwal, R., Chapleau, M. W. (2014). Autonomic, locomotor and cardiac abnormalities in a mouse model of muscular dystrophy: targeting the renin-angiotensin system. Exp Physiol, 99(4), 627-31. DOI: 10.1113/expphysiol.2013.074336.

Chen, K. H., Anderson, S. W., Grafft, A. & Chapleau, M. W. (2014). Habituation of parasympathetic-mediated heart rate responses to recurring acoustic startle. (Vols. 5). (Article 1288) Frontiers in Psychology.

Freeman, R., Chapleau, M. W. (2013). Testing the autonomic nervous system. Handb Clin Neurol, 115, 115-36. DOI: 10.1016/b978-0-444-52902-2.00007-2.

Lu, Y., Whiteis, C. A., Sluka, K. A., Chapleau, M. W. & Abboud, F. M. (2013). Reply from Y. Lu, C. A. Whiteis, K. A. Sluka, M. W. Chapleau and F. M. Abboud. J Physiol, 591(14), 3669. DOI: 10.1113/jphysiol.2013.256453.

Lu, Y., Whiteis, C. A., Sluka, K. A., Chapleau, M. W. & Abboud, F. M. (2013). Responses of glomus cells to hypoxia and acidosis are uncoupled, reciprocal and linked to ASIC3 expression: selectivity of chemosensory transduction. J Physiol, 591(4), 919-32. DOI: 10.1113/jphysiol.2012.247189.

Harwani, S. C., Chapleau, M. W., Legge, K. L., Ballas, Z. K. & Abboud, F. M. (2012). Neurohormonal modulation of the innate immune system is proinflammatory in the prehypertensive spontaneously hypertensive rat, a genetic model of essential hypertension. Circ Res, 111(9), 1190-7. DOI: 10.1161/circresaha.112.277475.

Robertson, D., Diedrich, A. & Chapleau, M. W. (2012). Editorial on arterial baroreflex issue. Auton Neurosci, 172(1-2), 1-3. DOI: 10.1016/j.autneu.2012.10.010.

Weiss, R. M., Sabharwal, R., Zimmerman, K. & Chapleau, M. W. (2011). Hypercholesterolemia and angiotensin-mediated hypertension act synergistically to produce aortic stenosis in middle-aged mice. (Vols. 25). pp. 641.12. FASEB.

Lu, Y., Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2011). Functional and molecular defects of baroreceptor neurons in genetic hypertension. (Vols. 23). J Physiol Proc Physiol Soc.

Sabharwal, R., Abboud, F. M. & Chapleau, M. W. (2011). Methionine sulfoxide reductase-A is required for normal baroreflex sensitivity and sympathovagal balance: evidence for redox regulation of autonomic function in young mice. (Vols. 21). pp. 218-219. Clin Autonom Res.

Sabharwal, R., Abboud, F. M., Russo, A. F. & Chapleau, M. W. (2011). Nervous system-targeted expression of CGRP/RAMP1 receptors enhances baroreflexes and opposes angiotensin-induced hypertension. (Vols. 23). pp. 101. J Physiol Proc Physiol Soc.

Kaufmann, H., Chapleau, M. W. (2011). Cardiovascular Regulation.

Sabharwal, R., Abboud, F. M., Russo, A. F. & Chapleau, M. W. (2011). Transgenic expression of CGRP receptor subunit RAMP1 in nervous system improves autonomic regulation and prevents angiotensin II hypertension. (Vols. 25). pp. 661.3. FASEB.

Wang, R., Whiteis, C. A., Benson, C. J., Chapleau, M. W. & Abboud, F. M. (2011). pH sensitivity of nodose ganglia neurons: Evidence for a pH conditioned Cl? conductance. Hypertension.

Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2011). Expression of miRNAs targeting genes controlling baroreceptor sensory transduction differs in SHR vs. WKY rats. (Vols. 25). pp. 606. FASEB.

Chapleau, M. W., Sabharwal, R. (2011). Methods of assessing vagus nerve activity and reflexes. Heart failure reviews, 16(2), 109-27. PMID: 20577901.

Harwani, S. C., Chapleau, M. & Abboud, F. M. (2011). Abnormal autonomic regulation of the immune system in genetic hypertension. (Vols. 25). pp. 640.34. FASEB.

Freeman, R., Chapleau, M. W. (2011). Assessment of Cardiovascular Autonomic Function.

Harwani, S. C., Chapleau, M., Legge, K., Ballas, Z. & Abboud, F. M. (2011). Autonomic dysregulation of innate immunity in genetic hypertension. Hypertension.

Peotta, V. A., Weiss, R. M., Zimmerman, K., Lu, Y., Russo, A. F., Abboud, F. M. & Chapleau, M. W. (2010). Consequences of enhanced CGRP receptor signaling on cardiac function and mortality post-myocardial infarction. (Vols. 24). pp. 1037.4. FASEB.

Sabharwal, R., Weiss, R. M., Zimmerman, K. & Chapleau, M. W. (2010). Differential sympathetic activation and blunted cardiovascular diurnal rhythms in a mouse model of hypertrophic cardiomyopathy. (Vols. 24). pp. 809.17. FASEB.

Sabharwal, R., Weiss, R. M., Zimmerman, K. & Chapleau, M. W. (2010). Autonomic dysregulation precedes and predicts cardiac dysfunction and mortality in a mouse model of muscular dystrophy. (Vols. 20). (5), pp. 300. Clin Autonom Res.

Sabharwal, R., Weiss, R. M. & Chapleau, M. W. (2010). Dysautonomia precedes cardiomyopathy in a mouse model of muscular dystrophy. (Vols. 51-52). pp. 51-52. Clin Autonom Res.

Lu, Y., Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2010). Molecular and functional phenotyping of baroreceptor neurons in spontaneously hypertensive rats. (Vols. 56). (5), pp. 108-109. Hypertension.

Sabharwal, R., Morgan, D. A., Whiteis, C. A., Rahmouni, K., Chapleau, M. W. & Abboud, F. M. (2010). ASIC2 dependent activation of the baroreceptors is required for the arterial baroreflex. (Vols. 24). pp. 625.1. FASEB.

Lu, Y., Whiteis, C. A., Chapleau, M. W., Sluka, K. & Abboud, F. M. (2010). Sensitivity to low pH in mouse glomus type 1 cells correlates with ASIC3 expression. (Vols. 24). pp. 691. FASEB.

Chapleau, M. W. (2010). CIH: from sleep apnea to breath-hold diving. Is sympathetic activation inevitable?. Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 20(2), 53-5. PMID: 20405161.

Flanagan, D. W., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2010). Angiotensin II-induced reactive oxygen species signaling in sympathetic ganglia. (Vols. 20). (5), pp. 321. Clin Autonom Res.

Sabharwal, R., Zhang, Z., Lu, Y., Abboud, F. M., Russo, A. F. & Chapleau, M. W. (2010). Receptor activity-modifying protein 1 increases baroreflex sensitivity and attenuates Angiotensin-induced hypertension. Hypertension, 55(3), 627-35. PMID: 20100989.

Lataro, R. M., Castania, J. A., Chapleau, M. W., Salgado, H. C. & Fazan, R. (2010). Baroreceptor and chemoreceptor contributions to the hypertensive response to bilateral carotid occlusion in conscious mice. American journal of physiology. Heart and circulatory physiology, 299(6), H1990-5. PMID: 20852042.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Simms, A. E., Paton, J. F., Chapleau, M. W. & Abboud, F. M. (2010). Chemoreceptor hypersensitivity, sympathetic excitation, and overexpression of ASIC and TASK channels before the onset of hypertension in SHR. Circulation research, 106(3), 536-45. PMID: 20019330.

Sabharwal, R., Weiss, R. M., Zimmerman, K. & Chapleau, M. W. (2010). Angiotensin II contributes to skeletal muscle fibrosis, reduced locomotor activity and autonomic dysfunction in ?-sarcoglycan deficient mice with muscular dystrophy. (Vols. 56). (5), pp. 301. Hypertension.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2009). Inhibition of TASK currents contributes to enhanced pH sensitivity of chemoreceptors in prehypertensive SHR. (Vols. 120). pp. 1160. Circulation.

Santana-Filho, V. J., Abboud, F. M. & Chapleau, M. W. (2009). Hydrogen peroxide mediates post-excitatory depression of baroreceptor afferent activity in vivo. (Vols. 23). pp. 1008.15. FASEB.

Fazan, V. P., Santana Filho, V. J., Fazan, R., Salgado, H. C., Moore, K. C. & Chapleau, M. W. (2009). Morphological differences in aortic depressor nerves of rats and mice: Implications for understanding the molecular/structural basis of baroreceptor function. (Vols. 14). pp. 46. Peripheral Nervous System.

Sabharwal, R., Weiss, R. M. & Chapleau, M. W. (2009). Dysautonomia precedes cardiomyopathy in a mouse model of muscular dystrophy. (Vols. 149). pp. 89-90. Autonomic Neuroscience.

Sabharwal, R., Weiss, R. M., Zimmerman, K. & Chapleau, M. W. (2009). Severe autonomic dysregulation in tropomyosin mutant mice: A possible contributor to arrhythmias and sudden death in hypertrophic cardiomyopathy. (Vols. 54). (4), pp. 85-86. Hypertension.

Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2009). Differential sensitivity of carotid body glomus cells to hypoxia and acidosis. (Vols. 23). pp. 1002.2. FASEB.

Roghair, R. D., Segar, J. L., Volk, K. A., Chapleau, M. W., Dallas, L. M., Sorenson, A. R., Scholz, T. D. & Lamb, F. S. (2009). Vascular nitric oxide and superoxide anion contribute to sex-specific programmed cardiovascular physiology in mice. American journal of physiology. Regulatory, integrative and comparative physiology, 296(3), R651-62. PMID: 19144750.

Fazan, R., Lu, Y. & Chapleau, M. W. (2009). CGRP selectively activates a subpopulation of nodose sensory neurons with tonic action potential firing properties. (Vols. 23). pp. 1008.16. FASEB.

Lu, Y., Ma, X., Sabharwal, R., Snitsarev, V., Morgan, D., Rahmouni, K., Drummond, H. A., Whiteis, C. A., Costa, V., Price, M., Benson, C., Welsh, M. J., Chapleau, M. W. & Abboud, F. M. (2009). The ion channel ASIC2 is required for baroreceptor and autonomic control of the circulation. Neuron, 64(6), 885-97. PMID: 20064394.

Sabharwal, R., Allen, J. E., Ziemann, A. E., Welsh, M. J., Wemmie, J. A. & Chapleau, M. W. (2009). Acid-sensing ion channel-1a contributes to fear-evoked behavioral and cardiovascular responses.

Sabharwal, R., Weiss, R. M. & Chapleau, M. W. (2009). Autonomic dysregulation in a mouse model of muscular dystrophy destined to develop dilated cardiomyopathy. (Vols. 23). pp. 1008.11. FASEB.

Sabharwal, R., Zhang, H. J., Stauss, H. M., Abboud, F. M., Russo, A. F. & Chapleau, M. W. (2008). Transgenic enhancement of CGRP signaling abrogates deleterious effects of angiotensin II on heart rate and blood pressure variability. (Vols. 52). (4), pp. 65. Hypertension.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2008). Molecular basis for hypersensitivity of chemoreceptor reflexes in spontaneously hypertensive rats (SHRs). (Vols. 52). (4), pp. 44. Hypertension.

Chapleau, M. W. (2008). Arterial Baroreflexes.

Lataro, R. M., Castania, J. A., Chapleau, M. W., Salgado, H. C. & Fazan, R. (2008). Contributions of baro- and chemoreceptors in mediating the hypertensive response to bilateral carotid occlusion in conscious mice. (Vols. 22). pp. 739.8. FASEB.

Sabharwal, R., Wemmie, J. A., Abboud, F. M. & Chapleau, M. W. (2008). Contrasting autonomic and cardiovascular phenotypes in ASIC1a and ASIC2 deficient mice. (Vols. 22). pp. 953.11. FASEB.

Lu, Y., Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2008). Single cell RT-PCR indicates lower ASIC2a mRNA expression in aortic baroreceptor neurons of adult SHR vs. WKY rats. (Vols. 22). pp. 953.6. FASEB.

Sabharwal, R., Zhang, H. J., Stauss, H. M., Abboud, F. M., Russo, A. F. & Chapleau, M. W. (2008). Enhancement of CGRP receptor signaling: A novel approach to improving autonomic regulation in normal and hypertensive states. (Vols. 18). (5), pp. 252-253. Clin Autonom Res.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2008). Molecular substrates of carotid body chemoreceptor activation. (Vols. 118). (18), pp. 360. Circulation.

Ziemann, A. E., Sabharwal, R., Welsh, M. J., Chapleau, M. W. & Wemmie, J. A. (2008). Acid-sensing ion channel-1a (ASIC1a) contributes to fear and associated autonomic/cardiovascular responses. (Vols. 22). pp. 946.8. FASEB.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2008). Selective sensitization of transduction pathways in carotid body glomus cells of spontaneously hypertensive rats. (Vols. 23). pp. 1002.4. FASEB.

Lin, M., Ai, J., Li, L., Huang, C., Chapleau, M. W., Liu, R., Gozal, D., Wead, W. B., Wurster, R. D. & Cheng, Z. '. (2008). Structural remodeling of nucleus ambiguus projections to cardiac ganglia following chronic intermittent hypoxia in C57BL/6J mice. The Journal of comparative neurology, 509(1), 103-17. PMID: 18425809.

Sabharwal, R., Wemmie, J. A., Abboud, F. M. & Chapleau, M. W. (2008). Acid-sensing ion channel-1a differentially contributes to blood pressure and heart rate responses to hypoxia and hypercapnia. (Vols. 22). pp. 739.5. FASEB.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2008). pH sensitive ion channels contribute to carotid body hypersensitivity in spontaneously hypertensive rats. (Vols. 18). (5), pp. 243. Clin Autonom Res.

Santana-Filho, V. J., Castania, J. A., Salgado, H. C., Chapleau, M. W. & Fazan, R. (2007). Endogenous cyclooxygenase metabolites limit post-excitatory depression of aortic baroreceptor activity in rats. pp. 36. Hypertension.

Sabharwal, R., Weiss, R. M., Stauss, H. M., Sigmund, C. D., Abboud, F. M. & Chapleau, M. W. (2007). Autonomic/baroreflex phenotypes in a novel mouse model of spontaneous congestive heart failure. (Vols. 17). (5), pp. 264. Clin Autonom Res.

Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2007). Decreased mRNA expression of ASIC2a in nodose sensory ganglia is associated with development of hypertension in SHR. (Vols. 21). (6), pp. 1405. FASEB.

Sabharwal, R., Weiss, R. M., Stauss, H. M., Sigmund, C. D. & Abboud, F. M. (2007). Autonomic and cardiovascular dysfunction in ApoE?/?R+A+ mice with chronic congestive heart failure. pp. 42. Hypertension.

Gu, H., Lin, M., Gozal, D., Scrogin, K. E., Chapleau, M. W. & Cheng, Z. (2007). Functional changes in afferent, central, and efferent components of the arterial baroreflex circuitry in F344 rats following chronic intermittent hypoxia. (Vols. 21). (6), pp. 823. FASEB.

Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2007). M-current in nodose sensory neurons mediates the depolarizing effect of prostacyclin. (Vols. 21). (6), pp. 1407. FASEB.

Mulvaney, J. M., Brooks, V. L., Roberts, D., Chapleau, M. W. & Goldman, R. K. (2007). Gain of baroreflex control of heart rate decreases during late pregnancy in rats. (Vols. 21). (5), pp. 512. FASEB.

Tan, Z. Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2007). pH sensitivity of carotid body glomus cells is augmented in spontaneously hypertensive rats. (Vols. 21). (6), pp. 1407. FASEB.

Peotta, V. A., Weiss, R. M., Sabharwal, R., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2007). Associations between cardiac dysfunction and decreased baroreflex sensitivity post-myocardial infarction in mice. pp. 45. Hypertension.

Abboud, F. M., Lu, Y. & Chapleau, M. W. (2007). Molecular Components of Neural Sensory Transduction: DEG/ENaC Proteins in Baro- and Chemoreceptors.

Sabharwal, R., Zhang, H. J., Abboud, F. M., Russo, A. F. & Chapleau, M. W. (2007). Genetic enhancement of CGRP receptor signaling increases baroreflex sensitivity and attenuates angiotensin-dependent hypertension. (Vols. 50). (4), pp. 86. Hypertension.

Chapleau, M. W., Lu, Y. & Abboud, F. M. (2007). Mechanosensitive Ion Channels in Blood-Pressure-Sensing Baroreceptor Neurons.

Snitsarev, V., Tan, Z. Y., Lu, Y., Sabharwal, R., Chapleau, M. W. & Abboud, F. M. (2007). Molecular mechanisms of reciprocal dysautonomia. (Vols. 17). (5), pp. 264. Clin Autonom Res.

Lin, M., Liu, R., Gozal, D., Wead, W. B., Chapleau, M. W., Wurster, R. & Cheng, Z. J. (2007). Chronic intermittent hypoxia impairs baroreflex control of heart rate but enhances heart rate responses to vagal efferent stimulation in anesthetized mice. American journal of physiology. Heart and circulatory physiology, 293(2), H997-1006. PMID: 17384123.

Ai, J., Gozal, D., Li, L., Wead, W. B., Chapleau, M. W., Wurster, R., Yang, B., Li, H., Liu, R. & Cheng, Z. (2007). Degeneration of vagal efferent axons and terminals in cardiac ganglia of aged rats. The Journal of comparative neurology, 504(1), 74-88. PMID: 17614301.

Chapleau, M. W. (2007). The continuing saga of neuronal oxidative stress in hypertension: Nox, Nox who's there, and where?. Hypertension, 50(4), 600-2. PMID: 17698720.

Gu, H., Lin, M., Liu, J., Gozal, D., Scrogin, K. E., Wurster, R., Chapleau, M. W., Ma, X. & Cheng, Z. J. (2007). Selective impairment of central mediation of baroreflex in anesthetized young adult Fischer 344 rats after chronic intermittent hypoxia. American journal of physiology. Heart and circulatory physiology, 293(5), H2809-18. PMID: 17693540.

Snitsarev, V., Costa-Bartlett, V., Petroff, E., Whiteis, C. A., Lu, Y., Chapleau, M. W., Welsh, M. J. & Abboud, F. M. (2007). ASIC2 expression is an important determinant of mechanotransduction in nodose neurons. Circulation.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Benson, C. J., Chapleau, M. W. & Abboud, F. M. (2007). Acid-sensing ion channels contribute to transduction of extracellular acidosis in rat carotid body glomus cells. Circulation research, 101(10), 1009-19. PMID: 17872465.

Sabharwal, R., Weiss, R. M., Stauss, H. M., Sigmund, C. D., Abboud, F. M. & Chapleau, M. W. (2007). ApoE?/?R+A+ mice with hypercholesterolemia, hypertension, and decreased baroreflex sensitivity spontaneously develop heart failure with age. (Vols. 21). (6), pp. 893. FASEB.

Chapleau, M. W. (2007). Exciting times in sensory transduction from A(drian) to Z. The Journal of physiology, 582(Pt 1), 13-4. PMID: 17463034.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Benson, C. J., Chapleau, M. W. & Abboud, F. M. (2007). Acid-sensing ion channels (ASICs) contribute to transduction of extracellular acidosis in rat carotid body glomus cells. Circulation.

Sabharwal, R., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Davisson, R. L., Price, M. P., Welsh, M. J., Abboud, F. M. & Chapleau, M. W. (2007). Abnormalities in baroreflex sensitivity and autonomic control in conscious ASIC2?/? mice. International Conference on Cardiopulmonary Regulation in Health Disease.

Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2007). Mechano- and chemosensitivity of rat nodose neurones--selective excitatory effects of prostacyclin. The Journal of physiology, 582(Pt 1), 177-94. PMID: 17478531.

Salgado, H. C., Barale, A. R., Castania, J. A., Machado, B. H., Chapleau, M. W. & Fazan, R. (2007). Baroreflex responses to electrical stimulation of aortic depressor nerve in conscious SHR. American journal of physiology. Heart and circulatory physiology, 292(1), H593-600. PMID: 16951050.

Sabharwal, R., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Price, M. P., Welsh, M. J., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2006). ASIC2-/- mice: A genetic model of impaired baroreceptor activation and oxidative stress-dependent neurogenic hypertension. Circulation.

Sabharwal, R., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Price, M. P., Welsh, M. J., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2006). ASIC2-/- mice: A genetic model of impaired baroreceptor activation and oxidative stress-dependent neurogenic hypertension. (Vols. 48). (4), pp. 31. Hypertension.

Lu, Y., Whiteis, C. A., Tan, Z. Y., Chapleau, M. W. & Abboud, F. M. (2006). Differential expression of acid-sensing ion channel (ASIC) subunits in rat carotid body. (Vols. 20). (5), pp. 1230. FASEB.

Tan, Z. Y., Whiteis, C. A., Lu, Y., Chapleau, M. W. & Abboud, F. M. (2006). Role of BK and ASIC in the activation of glomus cells by extracellular acidosis and hypoxia. (Vols. 20). (5), pp. 1230. FASEB.

Lu, Y., Whiteis, C. A., Benson, C. J., Chapleau, M. W. & Abboud, F. M. (2006). Expression and localization of acid-sensing ion channels in mouse nodose ganglia. (Vols. 20). (4), pp. 775. FASEB.

Sabharwal, R., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Price, M. P., Welsh, M. J., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2006). ASIC2-/- mice: A genetic model of impaired baroreceptor activation and neurogenic hypertension. (Vols. 16). (5), pp. 328. Clin Autonom Res.

Ma, X. Y., Tan, Z. Y., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2006). Sympathetic neurons isolated from apolipoprotein E deficient mice exhibit increased excitability: Role of oxidative stress. (Vols. 48). (4), pp. 35. Hypertension.

Peotta, V. A., Sabharwal, R., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2006). Gender differences in baroreflex sensitivity and lifespan in renin-angiotensinogen transgenic hypertensive mice. (Vols. 48). (4), pp. 46. Hypertension.

Santos, C. M., Chapleau, M., Young, M. E. & Michelini, L. (2006). The role of angiotensin II in isoproterenol-induced cardiomyocyte hypertrophy in mice. Brazilian Physiological Society.

Stauss, H. M., Moffitt, J. A., Chapleau, M. W., Abboud, F. M. & Johnson, A. K. (2006). Baroreceptor reflex sensitivity estimated by the sequence technique is reliable in rats. American journal of physiology. Heart and circulatory physiology, 291(1), H482-3. PMID: 16772526.

Ma, X., Bielefeldt, K., Tan, Z. Y., Whiteis, C. A., Snitsarev, V., Abboud, F. M. & Chapleau, M. W. (2006). Dual mechanisms of angiotensin-induced activation of mouse sympathetic neurones. The Journal of physiology, 573(Pt 1), 45-63. PMID: 16543267.

Ma, X. Y., Tian, X., Abboud, F. M. & Chapleau, M. W. (2006). Angiotensin-dependent upregulation of AT1 receptors increases NADPH oxidase expression in sympathetic ganglia of atherosclerotic mice. (Vols. 20). (5), pp. 1208. FASEB.

Morris, M., Jones, T. D., Rocha, M. J., Fazan, R., Chapleau, M. W., Salgado, H. C., Johnson, A. K., Irigoyen, M. C., Michelini, L. C. & Goldstein, D. L. (2006). International student exchange and the medical curriculum: evaluation of a medical sciences translational physiology course in Brazil. Advances in physiology education, 30(3), 119-23. PMID: 16912146.

Peotta, V. A., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Sabharwal, R., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2006). Aging-induced abnormalities in baroreflex and feed-forward control of heart rate at rest and during spontaneous activity in mice. (Vols. 20). (5), pp. 1209. FASEB.

Ma, X., Zhang, H. J., Whiteis, C. A., Tian, X., Davisson, R. L., Kregel, K. C., Abboud, F. M. & Chapleau, M. W. (2006). NAD(P)H oxidase-induced oxidative stress in sympathetic ganglia of apolipoprotein E deficient mice. Autonomic neuroscience : basic & clinical, 126-127, 285-91. PMID: 16584925.

Ma, X. Y., Tan, Z. Y., Tian, X., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2006). Angiotensin-dependent oxidative stress in sympathetic ganglia causes sympathoexcitation in apoE-/- mice. (Vols. 16). (5), pp. 330. Clin Autonom Res.

Sabharwal, R., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Davisson, R. L., Price, M. P., Welsh, M. J., Abboud, F. M. & Chapleau, M. W. (2006). Abnormalities in baroreflex sensitivity and autonomic control in conscious ASIC2?/? mice. (Vols. 20). (5), pp. 1186. FASEB.

Sabharwal, R., Chapleau, M., Price, M. P., Welsh, M. J. & Abboud, F. M. (2005). Molecular Mechanisms of Baro- and Chemoreceptor Activation: Evidence that ASIC1 and ASIC3 Contribute to Chemoreceptor Activation. (Vols. 46). (4), pp. 832. Hypertension.

Sabharwal, R., Chapleau, M., Price, M. P., Welsh, M. J. & Abboud, F. M. (2005). Molecular Mechanisms of Baro- and Chemoreceptor Activation: Evidence that ASIC1 and ASIC3 Contribute to Chemoreceptor Activation. (Vols. 112). (17), pp. II-156. Circulation.

Ma, X. Y., Tian, X., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2005). Increased Expression of NADPH Oxidase in Sympathetic Ganglia of Atherosclerotic Mice. (Vols. 119). pp. 133. Basic and Clinical.

Sabharwal, R., Chapleau, M., Price, M. P., Welsh, M. J. & Abboud, F. M. (2005). Subunits of Acid-sensing Ion Channels (ASICs) Differentially Mediate Baroreceptor and Chemoreceptor Reflexes. (Vols. 19). (5), pp. 1617-1618. FASEB.

Snitsarev, V., Iyer, K. S., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2005). Novel Molecular Defects in Mechanosensitivity of Aortic Baroreceptor Neurons from Spontaneously Hypertensive Rats. (Vols. 19). (4), pp. 607. FASEB.

Sabharwal, R., Chapleau, M., Price, M. P., Welsh, M. J. & Abboud, F. M. (2005). Subunits of Acid-sensing Ion Channels (ASICs) Differentially Mediate Baroreceptor and Chemoreceptor Reflexes. Iowa Physiological Society Meeting.

Lin, M., Chapleau, M., Liu, R., Gozal, D. & Cheng, Z. (2005). Chronic Intermittent Hypoxia Impairs Baroreflex Control of Heart Rate Despite Enhanced Heart Rate Response to Vagal Stimulation in Mice. Soc Neurosci Abstr.

Snitsarev, V., Iyer, K. S., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2005). Potassium Channel Defects Contribute to Decreased Excitability of Nodose Neurons in Spontaneously Hypertensive Rats. (Vols. 19). (4), pp. 606. FASEB.

Salgado, H., Rocha, M., Fazan, R., Michelini, L., Irigoyen, M. C., Chapleau, M. W., Johnson, A. K., Goldstein, D., Sulentic, C., Jones, D. & Beckley, C. (2005). Developing a Global Curriculum for the Medical Sciences.

Chapleau, M. W. (2005). Predicting cardiovascular risk--the madness is in the methods. Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 15(1), 10-2. PMID: 15768195.

Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2005). Neuronal prostacyclin is an autocrine regulator of arterial baroreceptor activity. Hypertension, 46(3), 540-6. PMID: 16061731.

Maheshwari, N., Lazartigues, E., Whiteis, C. A., Yerke, M., Davisson, R. L., Sigmund, C. D. & Chapleau, M. W. (2005). Cardiovascular Dysregulation and Reduced Lifespan in a Novel Mouse Model of Hypertension and Hypercholesterolemia. (Vols. 15). (5), pp. 322. Clin Autonom Res.

Fazan, R., de Oliveira, M., da Silva, V. J., Joaquim, L. F., Montano, N., Porta, A., Chapleau, M. W. & Salgado, H. C. (2005). Frequency-dependent baroreflex modulation of blood pressure and heart rate variability in conscious mice. American journal of physiology. Heart and circulatory physiology, 289(5), H1968-75. PMID: 15951338.

Morris, M., Michelini, L., Irigoyen, M. C., Chapleau, M. W., Johnson, A. K., Goldstein, D., Beckley, C. & Farah, V. D. (2005). Biomedical Research as a Key to International Education.

Lazartigues, E., Stauss, H. M., Yerke, M., Whiteis, C. A., Davisson, R. L., Sigmund, C. D., Abboud, F. M. & Chapleau, M. W. (2005). A Novel Mouse Model of Hypertension and Hypercholesterolemia with Reduced Life Span and Baroreflex Impairment. Hypertension.

Santos, C. M., Chapleau, M. & Michelini, L. C. (2005). Angiotensin II Contributes to Isoproterenol-induced Cardiomyocyte Hypertrophy in Normotensive Mice. FASEB.

Stauss, H. M., Lazartigues, E., Habib, A., Whiteis, C. A., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2005). Abnormalities in Baroreflex and Feed-Forward Control of Heart Rate in Conscious Hypertensive and Hypercholesterolemic Mice. (Vols. 46). (4), pp. 816. Hypertension.

Ma, X. Y., Zhang, H. J., Whiteis, C. A., Kregel, K. C., Abboud, F. M. & Chapleau, M. W. (2004). Oxidative Stress in Sympathetic Ganglia: A Possible Mechanism of Increased Sympathetic Nerve Activity and Impaired Baroreflex Sensitivity in Atherosclerosis. (Vols. 44). (4), pp. 523. Hypertension.

Lazartigues, E., Whiteis, C. A., Maheshwari, N., Abboud, F. M., Stauss, H. M., Davisson, R. L. & Chapleau, M. W. (2004). Oxidative Stress Contributes to Increased Sympathetic Vasomotor Tone and Decreased Baroreflex Sensitivity in Hypertensive and Hypercholesterolemic Mice. Iowa Physiological Society Meeting.

Lazartigues, E., Whiteis, C. A., Maheshwari, N., Abboud, F. M., Stauss, H. M., Davisson, R. L. & Chapleau, M. W. (2004). Oxidative Stress Contributes to Increased Sympathetic Vasomotor Tone and Decreased Baroreflex Sensitivity in Hypertensive and Hypercholesterolemic Mice. (Vols. 18). (4), pp. 299. FASEB.

Maheshwari, N., Lazartigues, E., Whiteis, C. A., Stauss, H. M., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2004). Partial Reversal of Baroreflex and Autonomic Dysfunction in Old Mice by Short-Duration (1-week) Antioxidant Therapy. Iowa Physiological Society Meeting.

Ma, X. Y., Sigmund, C. D., Hingtgen, S. D., Tian, X., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2004). Significant Contribution of a Ganglionic Action of Endogenous Angiotensin to Sympathetic Nerve Activity in Renin-Angiotensinogen Double Transgenic Mice. Iowa Physiological Society Meeting.

Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2004). Prostacyclin is an Autocrine Regulator of Excitability and Resetting of Baroreceptor Neurons. (Vols. 44). (4), pp. 524. Hypertension.

Chapleau, M. W., Abboud, F. M. (2004). The Baroreceptor Reflex: Novel Methods and Mechanisms.

Ma, X. Y., Sigmund, C. D., Hingtgen, S. D., Tian, X., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2004). Significant Contribution of a Ganglionic Action of Endogenous Angiotensin to Sympathetic Nerve Activity in Renin-Angiotensinogen Double Transgenic Mice. Iowa Physiological Society Meeting.

Stauss, H. M., Lazartigues, E., Sabharwal, R., Whiteis, C. A., Maheshwari, N., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2004). Role of Baroreflex in Short and Long-term Blood Pressure Regulation Assessed in Conscious Genetically-modified Mice.

Lazartigues, E., Maheshwari, N., Whiteis, C. A., Stauss, H. M., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2004). Restoration of Baroreflex Sensitivity and Cardiovagal Tone in Old Mice by Short-duration Antioxidant Therapy. (Vols. 14). (5), pp. 339. Clin Autonom Res.

Lazartigues, E., Whiteis, C. A., Maheshwari, N., Abboud, F. M., Stauss, H. M., Davisson, R. L. & Chapleau, M. W. (2004). Oxidative Stress Contributes to Increased Sympathetic Vasomotor Tone and Decreased Baroreflex Sensitivity in Hypertensive and Hypercholesterolemic Mice. (Vols. 18). (4), pp. 299. FASEB.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2004). Differential Expression of Transient K? Current (IA) in Tonic and Phasic Sympathetic Neurons and Its Inhibition by Angiotensin. FASEB.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2004). Differential Expression of Transient K+ Current and Its Inhibition by Angiotensin in Tonic and Phasic Sympathetic Neurons. Exp Biol.

Chapleau, M. W. (2004). Modulation of baroreflex function by altering inspiratory impedance: potential mechanisms and clinical implications. Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 14(4), 217-9. PMID: 15316837.

Sakai, K., Chapleau, M. W., Morimoto, S., Cassell, M. D. & Sigmund, C. D. (2004). Differential modulation of baroreflex control of heart rate by neuron- vs. glia-derived angiotensin II. Physiological genomics, 20(1), 66-72. PMID: 15467015.

Snitsarev, V., Yermolaieva, O., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2004). Hydrogen Peroxide/Hydroxyl Radical Generated during Action Potential Firing Inhibits Membrane Excitability of Baroreceptor and Vagal Afferent Neurons. (Vols. 14). (5), pp. 304. Clin Autonom Res.

Ma, X., Sigmund, C. D., Hingtgen, S. D., Tian, X., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2004). Ganglionic action of angiotensin contributes to sympathetic activity in renin-angiotensinogen transgenic mice. Hypertension, 43(2), 312-6. PMID: 14699002.

Snitsarev, V., Yermolaieva, O., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2004). Activity-dependent Resetting of Baroreceptor and Vagal Afferent Neurons Mediated by Endogenous Generation of Hydrogen Peroxide/Hydroxyl Radical. (Vols. 43). (6), pp. 1349. Hypertension.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2004). Differential Expression of Transient K? Current and Its Inhibition by Angiotensin in Tonic and Phasic Sympathetic Neurons. Exp Biol.

Snitsarev, V., Yermolaieva, O., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2004). Activity-dependent Resetting of Baroreceptor and Vagal Afferent Neurons Mediated by Hydrogen Peroxide/Hydroxyl Radical. Iowa Physiological Society Meeting.

Lazartigues, E., Whiteis, C. A., Maheshwari, N., Abboud, F. M., Stauss, H. M., Davisson, R. L. & Chapleau, M. W. (2004). Effects of Hypercholesterolemia, Hypertension, and their Interaction on Baroreflex Sensitivity and Cardiac Autonomic Tone: Role of Oxidative Stress. FASEB.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2004). Differential Expression of Transient K? Current and Its Inhibition by Angiotensin in Tonic and Phasic Sympathetic Neurons. Iowa Physiological Society Meeting.

Snitsarev, V., Yermolaieva, O., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2003). Modulation of Sensory Neuron Excitability by Endogenous ROS and Autocrine Factors. (Vols. 108). (17), pp. IV-57. Circulation.

Snitsarev, V., Sullivan, M. J., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2003). Molecular Basis of Mechanotransduction in Baroreceptor Neurons: Roles of Calcium-activated K? Current (IKca) and Actin. (Vols. 108). (17), pp. IV-57. Circulation.

Snitsarev, V., Yermolaieva, O., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2003). Modulation of Sensory Neuron Excitability by Endogenous ROS and Autocrine Factors. (Vols. 108). (17), pp. IV-57. Circulation.

Sakai, K., Chapleau, M. & Sigmund, C. D. (2003). Neuron-derived Angiotensin Causes Cardiac-Sympathetic Baroreflex Resetting in the Absence of Hypertension. (Vols. 42). (3), pp. 398. Hypertension.

Sakai, K., Morimoto, S., Chapleau, M. W. & Sigmund, C. D. (2003). Neuron- vs. Glia-derived Angiotensin II Differentially Modulate Baroreflex Control of Heart Rate in Conscious Transgenic Mice. Hypertension.

Ma, X. Y., Whiteis, C. A., Sigmund, C. D., Bielefeldt, K., Abboud, F. M. & Chapleau, M. W. (2003). Ganglionic Actions of Angiotensin Increase Sympathetic Nerve Activity: Contribution to Sympathoexcitation in Hypertension and Cellular Mechanisms. (Vols. 13). pp. 362. Clin Autonom Res.

Ma, X. Y., Sigmund, C. D., Hingtgen, S. D., Tian, X., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2003). Significant Contribution of a Ganglionic Action of Endogenous Angiotensin to Sympathetic Nerve Activity in Renin-Angiotensinogen Double Transgenic Mice. (Vols. 42). (3), pp. 408. Hypertension.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2003). Enhancement of Excitability of Tonic and Phasic Sympathetic Neurons by Angiotensin. (Vols. 17). (5), pp. 1294. FASEB.

Meyrelles, S. S., Sharma, R. V., Mao, H. Z., Abboud, F. M. & Chapleau, M. W. (2003). Modulation of baroreceptor activity by gene transfer of nitric oxide synthase to carotid sinus adventitia. American journal of physiology. Regulatory, integrative and comparative physiology, 284(5), R1190-8. PMID: 12676743.

Ma, X., Abboud, F. M. & Chapleau, M. W. (2003). Neurocardiovascular regulation in mice: experimental approaches and novel findings. Clinical and experimental pharmacology & physiology, 30(11), 885-93. PMID: 14678254.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2003). Enhancement of Excitability of Tonic and Phasic Sympathetic Neurons by Angiotensin. Iowa Physiological Society Meeting.

Chapleau, M. W. (2003). Determinants of baroreflex sensitivity in health and disease: from correlates to causality. Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 13(5), 310-3. PMID: 14564651.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2003). Activity-dependent Resetting of Baroreceptor Neurons in Culture: Role of Mechanosensitive vs. Voltage-gated Ion Channels. Iowa Physiological Society Meeting.

Fazan, R., de Oliveira, M., Dias da Silva, V. J., Chapleau, M. W. & Salgado, H. C. (2003). Effect of Autonomic Blockage on Arterial Pressure and Pulse Interval Variability in Conscious Mice. Hypertension.

Fazan, R., de Oliveira, M., Dias da Silva, V. J., Chapleau, M. W. & Salgado, H. C. (2003). Blood Pressure and Heart Rate Variability Spectra in Conscious Sinoaortic Denervated C57Bl Mice. (Vols. 17). (5), pp. 1230. FASEB.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Does Baroreceptor Resetting Occur in Isolated Baroreceptor Neurons in Culture. Nebraska Physiological Society.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Direct Activation of Sympathetic Neurons by Angiotensin is Mediated by Both Protein Kinase C-dependent and PKC-independent Mechanisms. Nebraska Physiological Society.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Does Baroreceptor Resetting Occur in Isolated Baroreceptor Neurons in Culture. (Vols. 16). (5), pp. 832. FASEB.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Nitric Oxide Functions as an Autocrine Negative-feedback Inhibitor of Membrane Excitability in Nodose Sensory Neurons. Society for Neuroscience.

Ma, X. Y., Sun, W., Snitsarev, V., Abboud, F. M. & Chapleau, M. W. (2002). Mechanisms of Baroreflex Impairment in Apo-E Knockout Mice with Atherosclerosis. (Vols. 29). pp. 92. Clin Exp Pharmacol Physiol.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Direct Activation of Sympathetic Neurons by Angiotensin is Mediated by Both Protein Kinase C-dependent and PKC-independent Mechanisms. (Vols. 16). (4), pp. 498. FASEB.

Snitsarev, V., Yermolaieva, O., Whiteis, C. A., Abboud, F. M., Heinemann, S. H., Hosi, T. & Chapleau, M. W. (2002). Reactive Oxygen Species Generated during Action Potential Discharge Mediate "Activity-dependent Resetting" of Baroreceptor and Vagal Afferent Neurons in Culture. (Vols. 106). (19), pp. II-66. Circulation.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Activity-dependent "Resetting" of Baroreceptor Neurons in Culture: Role of Mechanosensitive vs. Voltage-gated Ion Channels. (Vols. 106). (19), pp. II-294. Circulation.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Mechanosensory transduction of vagal and baroreceptor afferents revealed by study of isolated nodose neurons in culture. Autonomic neuroscience : basic & clinical, 98(1-2), 59-63. PMID: 12144042.

Fazan, V. P., Ma, X., Chapleau, M. W. & Barreira, A. A. (2002). Qualitative and quantitative morphology of renal nerves in C57BL/6J mice. The Anatomical record, 268(4), 399-404. PMID: 12420288.

Hausberg, M., Morgan, D. A., Chapleau, M. W., Sivitz, W. I., Mark, A. L. & Haynes, W. G. (2002). Differential Modulation of Leptin-induced Sympathoexcitation by Baroreflex Activation. J Hypertens, 20, 1633-1641.

Ma, X., Abboud, F. M. & Chapleau, M. W. (2002). Analysis of afferent, central, and efferent components of the baroreceptor reflex in mice. American journal of physiology. Regulatory, integrative and comparative physiology, 283(5), R1033-40. PMID: 12376395.

Chapleau, M. W., Sun, W. & Abboud, F. M. (2002). Altered Baro- and Chemoreflex Sensitivity in Young ApoE Knockout Mice before Development of Atherosclerotic Lesions. (Vols. 16). (5), pp. 828. FASEB.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Differential Activity-dependent "Resetting" of Subtypes of Isolated Baroreceptor Neurons in Culture. (Vols. 12). (4), pp. 305. Clin Autonom Res.

Sun, W., Ma, X. Y., Abboud, F. M. & Chapleau, M. W. (2002). Differential Effects of Aging on Baro- and Chemoreflex Regulation of Arterial Pressure: Selective Impairment of Baroreflex in Senescent Mice. (Vols. 12). (4), pp. 323. Clin Autonom Res.

Chapleau, M. W., Sun, W. & Abboud, F. M. (2002). Altered Baro- and Chemoreflex Sensitivity in Young ApoE Knockout Mice before Development of Atherosclerotic Lesions. Nebraska Physiological Society.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2001). Distinction Between Activation of Mechanosensitive Channels and Membrane Excitability in Isolated Nodose Sensory Neurons. (Vols. 15). (5), pp. 1150. FASEB.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2001). Effect of Prostacyclin Analog on Mechanosensitive vs. Voltage-gated Ion Channels in Nodose Neurons. (Vols. 27). pp. 1812. Soc Neurosci Abstr.

Chapleau, M. W., Abboud, F. M. (Eds.) (2001). Neuro-Cardiovascular Regulation: From Molecules to Man. (Vols. 940). Annals of the New York Academy of Sciences.

Sun, W., Ma, X. Y., Abboud, F. M. & Chapleau, M. W. (2001). Impaired Baroreflex and Enhanced Chemoreflex Sensitivity in Normotensive Atherosclerotic Mice. (Vols. 11). (3), pp. 187. Clin Autonom Res.

Ma, X. Y., Chapleau, M., Whiteis, C. A., Snitsarev, V., Abboud, F. M. & Bielefeldt, K. (2001). Differential Effects of Angiotensin on Membrane Potential and Action Potential Discharge of Phasic and Tonic Sympathetic Neurons of Mice. (Vols. 104). (17), pp. II-320. Circulation.

Abboud, F. M., Chapleau, M., Snitsarev, V. & Whiteis, C. A. (2001). Independent Assessment of Mechanosensitivity and Membrane Excitability in Isolated Nodose Sensory Neurons: Effect of the DEG/ENaC Blocker Amiloride. IUPS.

Ma, X., Abboud, F. M. & Chapleau, M. W. (2001). A novel effect of angiotensin on renal sympathetic nerve activity in mice. Journal of hypertension, 19(3 Pt 2), 609-18. PMID: 11327637.

Sun, W., Abboud, F. M. & Chapleau, M. W. (2001). Altered Baro- and Chemoreflex Sensitivity Revealed by Carotid Artery Occlusion Reflex in Apo-E Knockout Mice. (Vols. 15). (5), pp. 1146. FASEB.

Chapleau, M. W., Li, Z., Meyrelles, S. S., Ma, X. & Abboud, F. M. (2001). Mechanisms determining sensitivity of baroreceptor afferents in health and disease. Annals of the New York Academy of Sciences, 940, 1-19. PMID: 11458669.

Vasquez, E. C., Meyrelles, S. S., Chapleau, M. W. & Johnson, A. K. (2001). Approaches for gene delivery to the subfornical organ and magnocellular neurons. Clinical and experimental pharmacology & physiology, 28(7), 602-9. PMID: 11458888.

Chapleau, M. W., Abboud, F. M. (2001). Neuro-cardiovascular regulation: from molecules to man. Introduction. Annals of the New York Academy of Sciences, 940, xiii-xxii. PMID: 11458711.

Ma, X., Chapleau, M. W., Whiteis, C. A., Abboud, F. M. & Bielefeldt, K. (2001). Angiotensin selectively activates a subpopulation of postganglionic sympathetic neurons in mice. Circulation research, 88(8), 787-93. PMID: 11325870.

Abboud, F. M., Chapleau, M. & Sun, W. (2001). Altered Baro- and Chemoreflex Sensitivity in Apo-E Knockout Mice Revealed by Carotid Artery Occlusion. IUPS.

Fazan, R., Whiteis, C. A., Chapleau, M. W., Abboud, F. M. & Bielefeldt, K. (2001). Slow inactivation of sodium currents in the rat nodose neurons. Autonomic neuroscience : basic & clinical, 87(2-3), 209-16. PMID: 11476281.

Hausberg, M., Morgan, D. A., Chapleau, M. W., Mark, A. L. & Haynes, W. G. (2001). Regional Nonuniform Modulation of Leptin-induced Sympathoexcitation by Baroreflex Activation. Hypertension.

Ma, X. Y., Price, M. P., Drummond, H. A., Welsh, M. J., Chapleau, M. W. & Abboud, F. M. (2001). The DEG/ENaC Ion Channel Family Member BNC1 Mediates Mechanical Transduction of Arterial Baroreceptor Nerve Activity in Vivo. (Vols. 15). (5), pp. 1146. FASEB.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2001). Sensory Transduction of Vagal and Baroreceptor Afferents Revealed by Study of Isolated Nodose Neurons in Culture. Autonomic Neuroscience.

Abboud, F. M., Chapleau, M., Drummond, H. A., Ma, X. Y., Price, M. P. & Welsh, M. J. (2001). The DEG/ENaC Ion Channel Family Member BNC1 Contributes to Baroreceptor Mechanoelectrical Transduction in Vivo. IUPS.

Chapleau, M. W. (2000). Mechanisms Determining Sensitivity and Dysfunction of Baroreceptor Afferents in Health & Disease. (Vols. 43). (4), pp. 257. The Physiologist.

Sun, W., Chapleau, M. (2000). Paradoxical Dual Effects of Lidocaine on Carotid Occlusion Reflex in Mice. (Vols. 14). (4), pp. 382. FASEB.

Meyrelles, S. S., Abboud, F. M. & Chapleau, M. W. (2000). Reversal of Impaired Carotid Occlusion Reflex by Gene Transfer in Young Apo-E Deficient Mice. (Vols. 43). (4), pp. 276. The Physiologist.

Sun, W., Chapleau, M. (2000). Paradoxical Dual Effects of Lidocaine on Carotid Occlusion Reflex in Mice. (Vols. 18). (4), pp. 233. Hypertension.

Ma, X. Y., Bielefeldt, K., Abboud, F. M. & Chapleau, M. W. (2000). Selective Direct Activation of Subtype of Sympathetic Neurons by Angiotensin in Mice. (Vols. 18). (4), pp. 75. Hypertension.

Sun, W., Abboud, F. M. & Chapleau, M. W. (2000). Impaired Carotid Occlusion Reflex in ApoE Deficient Mice is Normalized with Age and Increasing Severity of Atherosclerotic Lesions. (Vols. 43). (4), pp. 276. The Physiologist.

Chapleau, M. W., Drummond, H. A., Meyrelles, S. S., Li, Z., Welsh, M. J. & Abboud, F. M. (2000). Molecular Mechanisms Determining Baroreceptor Sensitivity and their Modulation by Gene Transfer. (Vols. 82). pp. 9. Autonomic Neuroscience.

Ma, X. Y., Chapleau, M., Whiteis, C. A., Abboud, F. M. & Bielefeldt, K. (2000). Angiotensin Selectively Activates a Subpopulation of Post-ganglionic Sympathetic Neurons in Mice. (Vols. 14). (4), pp. 625. FASEB.

Whiteis, C. A., Fazan, R., Abboud, F. M. & Chapleau, M. W. (2000). Analysis of Baroreflex Sensitivity in Conscious Mice using Spectral Analysis. (Vols. 43). (4), pp. 275. The Physiologist.

Meyrelles, S. S., Chapleau, M. (2000). Impaired Carotid Occlusion Reflex in apoE Deficient Mice and its Reversal by Gene Transfer to Carotid Sinus. (Vols. 18). (4), pp. 202. Hypertension.

Ma, X. Y., Abboud, F. M. & Chapleau, M. W. (2000). Altered Baroreflex Control of Renal Sympathetic Nerve Activity in Normotensive Apo-E Deficient Atherosclerotic Mice. (Vols. 43). (4), pp. 275. The Physiologist.

Ma, X. Y., Fazan, R., Sun, W., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2000). Approaches to Define Autonomic Reflex Abnormalities in Genetically Modified Mice. (Vols. 10). (4), pp. 231. Clin Autonom Res.

Sun, W., Abboud, F. M. & Chapleau, M. W. (2000). Evaluation of Baroreflex and Chemoreflex by Carotid Artery Occlusion in Mice: A Method for Phenotypic Analysis of Deletion of Candidate Sensory Molecules. (Vols. 102). (18), pp. II-700. Circulation.

Ma, X. Y., Chapleau, M., Abboud, F. M. & Bielefeldt, K. (2000). Cellular Mechanism of Angiotensin-induced Activation of Postganglionic Sympathetic Neurons. (Vols. 26). (2), pp. 1953. Soc Neurosci Abstr.

Fazan, R., Ma, X. Y., Barreira, A. A., Abboud, F. M. & Chapleau, M. W. (1999). Qualitative and Quantitative Electron Microscopy Study of the Renal Nerves in C57 Black Mice. J Med Biol Res.

Fazan, R., Shaffer, R. A., Abboud, F. M. & Chapleau, M. W. (1999). Parasympathetic and Sympathetic Contributions to Heart Rate and Arterial Pressure Variability in Conscious Mice. (Vols. 13). (4), pp. 453. FASEB.

Meyrelles, S. S., Chapleau, M. (1999). Analysis of Carotid Baroreflex using Sequential Carotid Occlusion and Gene Transfer in Mice. (Vols. 33). (4), pp. 1085. Hypertension.

Fazan, R., Ma, X. Y., Abboud, F. M. & Chapleau, M. W. (1999). An Electron Microscopy Study of the Renal Nerves in C57 Black Mice. (Vols. 13). (4), pp. 143. FASEB.

Chapleau, M. W., Ma, X. Y. & Abboud, F. M. (1999). Novel Dual Effects of Angiotensin on the Pattern and Type of Sympathetic Outflow to Kidney in Mice. (Vols. 33). (4), pp. 1071. Hypertension.

Ma, X. Y., Abboud, F. M. & Chapleau, M. W. (1999). Angiotensin-induced Activation of "Silent" Renal Sympathetic Nerves in Mice. (Vols. 13). (5), pp. 776. FASEB.

Chapleau, M. W., Drummond, H. A., Welsh, M. J. & Abboud, F. M. (1999). Mechanisms of Sensory Transduction of Blood-Pressure-Sensing-Neurons in the Cardiovascular System. Japan Neuroscience Symposium.

Fazan, R., Abboud, F. M., Chapleau, M. W. & Bielefeldt, K. (1999). Effects of Nitric Oxide on Inactivation Processes of Sodium Currents in Nodose Neurons. (Vols. 13). (5), pp. 777. FASEB.

Meyrelles, S. S., Chapleau, M. (1999). Carotid Baroreflex Control of Arterial Pressure Studied by Sequential Carotid Occlusion in Mice. (Vols. 13). (5), pp. 775. FASEB.

Bielefeldt, K., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (1999). Nitric oxide enhances slow inactivation of voltage-dependent sodium currents in rat nodose neurons. Neuroscience letters, 271(3), 159-62. PMID: 10507693.

Chapleau, M. W. (1999). Arterial Baroreflexes.

Ma, X. Y., Sigmund, C. D., Abboud, F. M. & Chapleau, M. W. (1999). Impaired Central Mediation of the Baroreflex in Human Renin/Human Angiotensinogen Double Transgenic Hypertensive Mice. (Vols. 25). (2), pp. 1948. Soc Neurosci Abstr.

Ma, X. Y., Shaffer, R. A., Sigmund, C. D., Abboud, F. M. & Chapleau, M. W. (1999). Mechanisms of Impaired Baroreflex Control of Sympathetic Nerve Activity in Hypertensive Renin-Angiotensinogen Double Transgenic Mice. (Vols. 13). (5), pp. 775. FASEB.

Fazan, R., Shaffer, R. A., Abboud, F. M. & Chapleau, M. W. (1999). Mechanisms of Heart Rate and Arterial Pressure Variability in Conscious Mice. (Vols. 33). (4), pp. 1076. Hypertension.

Meyrelles, S. S., Sharma, R. V. & Chapleau, M. W. (1998). Gene Transfer to Nodose Sensory Neurons in Culture and to Carotid Sinus in Vivo. American Society of Gene Therapy.

Fazan, R., Chapleau, M., Abboud, F. M. & Bielefeldt, K. (1998). Use-dependent Modulation of Sodium Channels in Nodose Sensory Neurons. (Vols. 24). (1), pp. 1076. Soc Neurosci Abstr.

Ma, X. Y., Shaffer, R. A., Abboud, F. M. & Chapleau, M. W. (1998). Functional Genomics: Analysis of Afferent, Central and Efferent Components of Baroreceptor Reflex in Mice. (Vols. 12). (4), pp. 359. FASEB.

Davis, G. J., Fazan, R., Abboud, F. M. & Chapleau, M. W. (1998). Brief Activation of Baroreceptor C-Fibers Causes Sustained Inhibition of Baroreceptor Activity: Possible Mechanism of Baroreceptor Resetting Following Acute Hypertension. (Vols. 46). (3), pp. 200. J Invest Med.

Li, Z., Chapleau, M. W., Bates, J. N., Bielefeldt, K., Lee, H. C. & Abboud, F. M. (1998). Nitric oxide as an autocrine regulator of sodium currents in baroreceptor neurons. Neuron, 20(5), 1039-49. PMID: 9620707.

Ma, X. Y., Abboud, F. M. & Chapleau, M. W. (1998). Baroreceptor Sensitivity and Baroreflex Control of Renal Sympathetic Nerve Activity in Mice. (Vols. 46). (3), pp. 200. J Invest Med.

Kraske, S., Cunningham, J. T., Hajduczok, G., Chapleau, M. W., Abboud, F. M. & Wachtel, R. E. (1998). Mechanosensitive ion channels in putative aortic baroreceptor neurons. The American journal of physiology, 275(4 Pt 2), H1497-501. PMID: 9746502.

Davis, G. J., Fazan, R., Abboud, F. M. & Chapleau, M. W. (1998). "Autocrine" Activity-dependent Inhibition of Baroreceptor Activity: A Novel Mechanism of Baroreceptor Resetting. (Vols. 24). (1), pp. 871. Soc Neurosci Abstr.

Meyrelles, S. S., Mao, H. Z., Sharma, R. V. & Chapleau, M. W. (1998). Baroreceptor Resetting and Vessel Remodeling after Gene Transfer of Nitric Oxide Synthase to Carotid Sinus. (Vols. 12). (5), pp. 687. FASEB.

Meyrelles, S. S., Mao, H. Z., Sharma, R. V., Heistad, D. D. & Chapleau, M. W. (1997). Modulation of Baroreceptor Sensitivity by Gene Transfer of Nitric Oxide Synthase to Carotid Sinus Adventitia. (Vols. 30). (3), pp. 471. Hypertension.

Abboud, F. M., Chapleau, M. W. (1997). Modulation of Mechanotransduction in Aortic Baroreceptor Neurons. Fundam Clin Pharmacol, 11(1), 58s-63s.

Li, Z., Lee, H., Bates, J. N., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (1997). Nitric Oxide Inhibits Sodium Current of Rat Aortic Baroreceptor Neurons. (Vols. 45). (3), pp. 221. J Invest Med.

Li, Z., Bates, J. N., Lee, H., Abboud, F. M. & Chapleau, M. W. (1997). Oxidation Selectively Inhibits Tetrodotoxin-Sensitive Sodium Current in Isolated Baroreceptor Neurons. (Vols. 23). (2), pp. 1519. Soc Neurosci Abstr.

Li, Z., Lee, H., Bates, J. N., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (1997). Nitric Oxide Inhibits Sodium Currents of Baroreceptor Neurons by Nitrosylation Independent of Cyclic GMP. (Vols. 96). (8), pp. I-444. Circulation.

Heistad, D., Faraci, F., Ooboshi, H. & Chapleau, M. W. (1997). Gene Transfer to Blood Vessels and Carotid Sinus. (Vols. 65). pp. 67. J Auton Nerv Syst.

Meyrelles, S. S., Sharma, R. V., Davidson, B. L. & Chapleau, M. W. (1997). Selective Induction of Endogenous ?-Gal Gene Expression in Nodose Sensory Neurons In Vivo. (Vols. 11). (3), pp. 17. FASEB.

Chapleau, M. W., Li, Z., Lee, H., Bates, J. N., Whiteis, C. A. & Abboud, F. M. (1997). Inhibition of Sodium Currents in Cultured Baroreceptor Neurons by Nitric Oxide. Proc Int Union Physiol Sci.

Li, Z., Chapleau, M., Bates, J. N., Lee, H., Whiteis, C. A. & Abboud, F. M. (1997). Differential Inhibitory Effects of Nitric Oxide and the Oxidizing Agent Dithiodipyridine on Sodium Currents of Baroreceptor Neurons. (Vols. 96). (8), pp. I-444. Circulation.

Li, Z., Lee, H. C., Bielefeldt, K., Chapleau, M. W. & Abboud, F. M. (1997). The prostacyclin analogue carbacyclin inhibits Ca(2+)-activated K+ current in aortic baroreceptor neurones of rats. The Journal of physiology, 501 ( Pt 2), 275-87. PMID: 9192300.

Sullivan, M. J., Sharma, R. V., Wachtel, R. E., Chapleau, M. W., Waite, L. J., Bhalla, R. C. & Abboud, F. M. (1997). Non-voltage-gated Ca2+ influx through mechanosensitive ion channels in aortic baroreceptor neurons. Circulation research, 80(6), 861-7. PMID: 9168789.

Chapleau, M. W., Meyrelles, S. S., Mao, H. Z., Sharma, R. V. & Heistad, D. D. (1997). Gene Transfer into Nodose Sensory Neurons in Culture and into Carotid Sinus In Vivo. Proc Int Union Physiol Sci.

Meyrelles, S. S., Mao, H. Z., Heistad, D. D. & Chapleau, M. W. (1997). Gene transfer to carotid sinus in vivo: a novel approach to investigation of baroreceptors. Hypertension, 30(3 Pt 2), 708-13. PMID: 9323010.

Su, X., Chapleau, M. & Gebhart, G. F. (1997). Effect of Antidepressants on Mechanosensitive Pelvic Nerve Afferent Fibers Innervating the Colon of the Rat. (Vols. 112). pp. 833. Gastroenterology.

Meyrelles, S. S., Mao, H. Z., Mora, M., Sharma, R. V., Ooboshi, H. & Chapleau, M. W. (1997). Gene Transfer into Baroreceptor Sensory Neurons and Carotid Sinus. (Vols. 45). (3), pp. 221. J Invest Med.

Meyrelles, S. S., Sharma, R. V., Whiteis, C. A., Davidson, B. L. & Chapleau, M. W. (1997). Adenovirus-mediated gene transfer to cultured nodose sensory neurons. Brain research. Molecular brain research, 51(1-2), 33-41. PMID: 9427504.

Meyrelles, S. S., Mao, H. Z., Mora, M., Sharma, R. V., Ooboshi, H. & Chapleau, M. W. (1997). Gene Transfer into Baroreceptor Sensory Neurons and Carotid Sinus. (Vols. 29). (3), pp. 888. Hypertension.

Li, Z., Lee, H., Bielefeldt, K., Abboud, F. M. & Chapleau, M. W. (1996). K+ Channels Mediate Prostacyclin-induced Increase in Excitability of Mechanosensitive Baroreceptor Neurons. Neuropharmacology.

Li, Z., Lee, H., Bielefeldt, K., Abboud, F. M. & Chapleau, M. W. (1996). K+ Current Inhibition by Prostacyclin Analog Carbacyclin in Baroreceptor Neurons Requires G-Protein Activation and cAMP Formation. (Vols. 10). (3), pp. 16. FASEB.

Li, Z., Chapleau, M., Lee, H., Bates, J. N. & Abboud, F. M. (1996). Nitric Oxide Inhibits Na+ Current of Isolated Baroreceptor Neurons in Culture. (Vols. 44). (3), pp. 247. J Invest Med.

Li, Z., Lee, H., Bates, J. N., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (1996). Nitric Oxide (NO) Inhibits Sodium Current of Rat Aortic Baroreceptor Neurons. (Vols. 94). (8), pp. I-491. Circulation.

Nuyt, A. M., Holley, A. T., Chemtob, S., Chapleau, M. W., Segar, J. L. & Robillard, J. E. (1996). Role of Endogenous Prostaglandins in the Regulation of Arterial Baroreceptor Activity During Development. (Vols. 39). (4), pp. 234. Pediatric Res.

Nuyt, A. M., Holley, A. T., Chapleau, M. W. & Robillard, J. E. (1996). Effect of Nitric Oxide (NO) on Arterial Baroreflex Baroreceptor Activity During Development. (Vols. 39). (4), pp. 77. Pediatric Res.

Li, Z., Mao, H. Z., Abboud, F. M. & Chapleau, M. W. (1996). Oxygen-derived free radicals contribute to baroreceptor dysfunction in atherosclerotic rabbits. Circulation research, 79(4), 802-11. PMID: 8831504.

Nuyt, A. M., Merrill, D. C., Segar, J. L., Chapleau, M. W. & Robillard, J. E. (1996). Autonomic Adjustments to Severe Hypotension During Fetal and Postnatal Life: Ontogeny of the Bezold-Jarisch Reflex. (Vols. 39). (4), pp. 33. Pediatric Res.

Nuyt, A. M., Segar, J. L., Holley, A. T., O'Mara, M. S., Chapleau, M. W. & Robillard, J. E. (1996). Arginine vasopressin modulation of arterial baroreflex responses in fetal and newborn sheep. The American journal of physiology, 271(6 Pt 2), R1643-53. PMID: 8997365.

Mao, H. Z., Li, Z. & Chapleau, M. W. (1996). Platelet activation in carotid sinuses triggers reflex sympathoinhibition and hypotension. Hypertension, 27(3 Pt 2), 584-90. PMID: 8613208.

Meyrelles, S. S., Sharma, R. V., Whiteis, C. A., Davidson, B. L. & Chapleau, M. W. (1996). Adenoviral-mediated Gene Transfer into Baroreceptor Neurons. (Vols. 10). (3), pp. 62. FASEB.

Chapleau, M. W., Su, X. & Li, Z. (1995). Platelets Aggregating in Carotid Sinus Selectively Modulate Activity of Baroreceptor Fiber Types. (Vols. 9). (3), pp. 7. FASEB.

Mao, H. Z., Chapleau, M. (1995). Platelets Aggregating in Carotid Sinuses Trigger Reflex Inhibition of Sympathetic Nerve Activity and Hypotension. (Vols. 26). (3), pp. 559. Hypertension.

Li, Z., Lee, H., Bielefeldt, K., Chapleau, M. W. & Abboud, F. M. (1995). The Prostacyclin Analog Carbacyclin Increases the Excitability of Isolated Baroreceptor Neurons and Inhibits Outward K+ Current. (Vols. 43). (3), pp. 451. J Invest Med.

Li, Z., Lee, H., Bielefeldt, K., Chapleau, M. W. & Abboud, F. M. (1995). Prostacyclin Analog Carbacyclin Inhibits Ca2+- Activated K+ Current in Cultured Baroreceptor Neurons. (Vols. 21). (3), pp. 1831. Soc Neurosci Abstr.

Su, X., Li, Z. & Chapleau, M. W. (1995). Activated Platelets Alter Activity of Baroreceptor Fiber Types in a Selective and Differential Manner. AHA.

Li, Z., Lee, H., Bielefeldt, K., Abboud, F. M. & Chapleau, M. W. (1995). The Prostacyclin Analog Carbacyclin Enhances Membrane Excitability of Isolated Baroreceptor Neurons in Culture. (Vols. 92). (8), pp. I-134. Circulation.

Chapleau, M. W., Sullivan, M. J., Cunningham, J. T., Wachtel, R. E. & Abboud, F. M. (1995). Mechanoelectrical Transduction in Baroreceptor Neurons - Evidence of Stretch-Activated Ion Channels. (Vols. 16). pp. 458. Eur Heart J.

Sharma, R. V., Chapleau, M. W., Hajduczok, G., Wachtel, R. E., Waite, L. J., Bhalla, R. C. & Abboud, F. M. (1995). Mechanical stimulation increases intracellular calcium concentration in nodose sensory neurons. Neuroscience, 66(2), 433-41. PMID: 7477884.

Li, Z., Su, X. & Chapleau, M. W. (1995). Role of cyclooxygenase metabolites in mediating platelet-induced baroreceptor dysfunction. The American journal of physiology, 269(2 Pt 2), H599-608. PMID: 7653624.

Nuyt, A. M., Mao, H. Z., Abboud, F. M. & Chapleau, M. W. (1995). Nitric Oxide Modulates Arterial Baroreceptor Activity via Ca-Activated K Channels In Vivo. (Vols. 37). (4), pp. 31. Pediatric Res.

Chapleau, M. W., Cunningham, J. T., Sullivan, M. J., Wachtel, R. E. & Abboud, F. M. (1995). Structural versus functional modulation of the arterial baroreflex. Hypertension, 26(2), 341-7. PMID: 7543454.

Matsuda, T., Bates, J. N., Lewis, S. J., Abboud, F. M. & Chapleau, M. W. (1995). Modulation of baroreceptor activity by nitric oxide and S-nitrosocysteine. Circulation research, 76(3), 426-33. PMID: 7859388.

Chapleau, M. W., Hajduczok, G., Sharma, R. V., Wachtel, R. E., Cunningham, J. T., Sullivan, M. J. & Abboud, F. M. (1995). Mechanisms of baroreceptor activation. Clinical and experimental hypertension (New York, N.Y. : 1993), 17(1-2), 1-13. PMID: 7735260.

Li, Z., Chapleau, M. W. (1995). Platelet-induced suppression of baroreceptor activity is mediated by a stable diffusible factor. Journal of the autonomic nervous system, 51(1), 59-65. PMID: 7722216.

Chapleau, M. W., Matsuda, T., Mao, H. Z., Su, X. & Abboud, F. M. (1994). Modulation of Baroreceptor Activity by NO: Implications for Blood Pressure Regulation. Therapeutic Application and Commercial Development.

Su, X., Chapleau, M. (1994). Nitric Oxide Released from Carotid Sinus Sensory Nerves Inhibits Activity of Baroreceptor A-Fibers. (Vols. 37). (4), pp. A-8. The Physiologist.

Cunningham, J. T., Kraske, S., Fankhauser, L., Wachtel, R. E., Chapleau, M. W. & Abboud, F. M. (1994). Whole Cell Currents Induced by Hypoosmotic Stretch in Nodose Ganglion Neurons. (Vols. 8). (4), pp. 332. FASEB.

Mao, H. Z., Su, X. & Chapleau, M. W. (1994). The Antidepressant Phenelzine Causes Centrally-Mediated Inhibition of Sympathetic Nerve Activity: A Possible Cause of Orthostatic Hypotension. (Vols. 90). (4), pp. I-474. Circulation.

Mao, H. Z., Li, Z. & Chapleau, M. W. (1994). The Antidepressant Phenelzine Suppresses Baroreceptor Activity through a Nitric Oxide Dependent Mechanism. (Vols. 8). (4), pp. 334. FASEB.

Chapleau, M. W., Sullivan, M. J., Cunningham, J. T., Wachtel, R. E., Mao, H. Z. & Abboud, F. M. (1994). Evidence that Gadolinium-Sensitive Stretch-Activated Ion Channels Are the Arterial Baroreceptor Mechano-transducers. FASEB.

Hajduczok, G., Chapleau, M. W., Ferlic, R. J., Mao, H. Z. & Abboud, F. M. (1994). Gadolinium inhibits mechanoelectrical transduction in rabbit carotid baroreceptors. Implication of stretch-activated channels. The Journal of clinical investigation, 94(6), 2392-6. PMID: 7527431.

Sullivan, M. J., Sharma, R. V., Wachtel, R. E., Chapleau, M. W., Fankhauser, L., Bhalla, R. C. & Abboud, F. M. (1994). Mechanism of Mechano-electrical Transduction in Putative Baroreceptor Neurons. (Vols. 42). (2), pp. 257. Clin Res.

Chapleau, M. W., Abboud, F. M. (1994). Modulation of baroreceptor activity by ionic and paracrine mechanisms: an overview. Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], 27(4), 1001-15. PMID: 7522078.

McDowell, T. S., Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1994). Baroreflex dysfunction in diabetes mellitus. I. Selective impairment of parasympathetic control of heart rate. The American journal of physiology, 266(1 Pt 2), H235-43. PMID: 8304504.

Sullivan, M. J., Sharma, R. V., Chapleau, M. W., Wachtel, R. E., Fankhauser, L., Bhalla, R. C. & Abboud, F. M. (1994). Baroreceptor Neurons Respond to Mechanical Stimulation with Increases in Intracellular Calcium. (Vols. 8). (4), pp. 334. FASEB.

McDowell, T. S., Hajduczok, G., Abboud, F. M. & Chapleau, M. W. (1994). Baroreflex dysfunction in diabetes mellitus. II. Site of baroreflex impairment in diabetic rabbits. The American journal of physiology, 266(1 Pt 2), H244-9. PMID: 8304505.

Abboud, F. M., Chapleau, M. (1993). Mechanisms of Adaptation and Resetting of the Baroreceptor Reflex. Proc Int Union Physiol Sci.

Mao, H. Z., Li, Z. & Chapleau, M. W. (1993). The Antidepressant Tranylcypromine Causes Profound Impairment of Baroreceptor Sensitivity. (Vols. 88). (4), pp. I-362. Circulation.

Li, Z., Abboud, F. M. & Chapleau, M. W. (1993). Oxygen-Derived Free Radicals Contribute to Baroreceptor Dysfunction in Atherosclerosis. (Vols. 7). (3), pp. 94. FASEB.

Chapleau, M. W., Abboud, F. M. (1993). Mechanisms of Adaptation and Resetting of the Baroreceptor Reflex.

Chapleau, M. W., Li, Z. & Abboud, F. M. (1993). Oxygen-Derived Free Radicals Suppress Baroreceptor Activity: A Mechanism of Baroreceptor Dysfunction in Atherosclerosis. Proc Int Union Physiol Sci.

Chapleau, M. W., Lu, J., Hajduczok, G. & Abboud, F. M. (1993). Mechanism of baroreceptor adaptation in dogs: attenuation of adaptation by the K+ channel blocker 4-aminopyridine. The Journal of physiology, 462, 291-306. PMID: 8331585.

Li, Z., Chapleau, M. (1993). Mechanisms Involved in Platelet-Induced Baroreceptor Dysfunction. Proc Int Union Physiol Sci.

Segar, J. L., Merrill, D. C., Chapleau, M. W. & Robillard, J. E. (1993). Hemodynamic changes during endotracheal suctioning are mediated by increased autonomic activity. Pediatric research, 33(6), 649-52. PMID: 8378127.

Mao, H. Z., Li, Z. & Chapleau, M. W. (1993). Antidepressant Agents Impair Baroreceptor Sensitivity: A Possible Mechanism of Orthostatic Hypotension. (Vols. 41). (3), pp. 628. Clin Res.

Ma, S., Felder, R. B., Chapleau, M. W. & Abboud, F. M. (1993). Effects of Nitroglycerin on Neuronal Activity in the Solitary Tract Nucleus In Vivo and In Vitro. (Vols. 7). (3), pp. 99. FASEB.

Sharma, R. V., Wachtel, R. E., Hajduczok, G., Chapleau, M. W., Fankhauser, L., Bhalla, R. C. & Abboud, F. M. (1993). Calcium Influx Mediates Mechano-sensitive Intracellular Calcium Transients in Nodose Sensory Neurons. (Vols. 7). (3), pp. 94. FASEB.

Chapleau, M. W., Li, Z. (1992). Endogenous Prostanoids Oppose Platelet-Induced Suppression of Baroreceptor Activity. (Vols. 86). (4), pp. I-15. Circulation.

Matsuda, T., Chapleau, M., Lewis, S. J., Bates, J. N. & Abboud, F. M. (1992). Endothelial Factors S-Nitrosocysteine (CysNO) and Nitric Oxide (NO) Suppress Baroreceptor Activity. (Vols. 6). (4), pp. 952. FASEB.

Ma, S., Chapleau, M. & Abboud, F. M. (1992). Paradoxical Bradycardia and Sympathoinhibition by Nitroglycerin Occurs in Old but Not Young Rats and is Related to Impaired Baroreflexes. (Vols. 40). (2), pp. 155. Clin Res.

Matsuda, T., Chapleau, M., Bates, J. N., Lewis, S. J. & Abboud, F. M. (1992). Modulation of Baroreceptor Activity by Nitric Oxide. (Vols. 40). (3), pp. 702. Clin Res.

Matsuda, T., Chapleau, M., Bates, J. N., Lewis, S. J. & Abboud, F. M. (1992). Endogenous Nitric Oxide Suppresses Barorecep¬tor Activity by a cGMP Independent Mechanism. (Vols. 86). (4), pp. I-482. Circulation.

Li, Z., Abboud, F. M. & Chapleau, M. W. (1992). Oxygen Derived Free Radicals Suppress Carotid Sinus Nerve Activity: Possible Mechanism of Baroreceptor Dysfunction in Atherosclerosis. (Vols. 86). (4), pp. I-483. Circulation.

Ma, S., Chapleau, M. & Abboud, F. M. (1992). Defect in Central Mediation of the Baroreflex with Aging. (Vols. 6). (4), pp. 951. FASEB.

Chapleau, M. W., Abboud, F. M. (1992). Does prostacyclin sensitize arterial baroreceptors?. The American journal of physiology, 262(2 Pt 2), H621-2. PMID: 1610443.

Chapleau, M. W. (1992). Are arterial pressure and deformation the sole determinants of baroreceptor activity? Importance of humoral and endothelial modulation in normal and disease states. Hypertension, 19(3), 278-80. PMID: 1548052.

Li, Z., Abboud, F. M. & Chapleau, M. W. (1992). Aggregating human platelets in carotid sinus of rabbits decrease sensitivity of baroreceptors. Circulation research, 70(4), 644-50. PMID: 1551191.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1992). Suppression of baroreceptor discharge by endothelin at high carotid sinus pressure. The American journal of physiology, 263(1 Pt 2), R103-8. PMID: 1636777.

Lu, J. J., Abboud, F. M. & Chapleau, M. W. (1992). Absence of Acute Resetting in a Subpopulation of Baroreceptors (BR) During Hypertension. (Vols. 6). (4), pp. 1524. FASEB.

Chapleau, M. W. (1992). Cardiovascular Mechanoreceptors.

Li, Z., Chapleau, M. (1992). Activated Platelets Release a Stable Diffusible Mediator that Suppresses Baroreceptor Activity. (Vols. 40). (3), pp. 727. Clin Res.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1991). Paracrine role of prostanoids in activation of arterial baroreceptors: an overview. Clinical and experimental hypertension. Part A, Theory and practice, 13(5), 817-24. PMID: 1773513.

Li, Z., Chapleau, M. (1991). Platelet Products Modulate Sensitivity of Arterial Baroreceptors: Role of Thromboxane, Serotonin, and ADP. (Vols. 84). (4), pp. II-99. Circulation.

Hajduczok, G., Chapleau, M. W. & Abboud, F. M. (1991). Rapid adaptation of central pathways explains the suppressed baroreflex with aging. Neurobiology of aging, 12(5), 601-4. PMID: 1770991.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1991). Resetting of the Arterial Baroreflex: Peripheral and Central Mechanisms.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1991). Paracrine Modulation of Baroreceptor Activity by Vascular Endothelium. News Physiol Sci, 6, 210-214.

Li, Z., Abboud, F. M. & Chapleau, M. W. (1991). Neural Discharge from Arterial Baroreceptors is Suppressed by Aggregating Platelets and Damaged Endothelium - Possible Mechanism of Neurogenic Hypertension in Atherosclerosis. (Vols. 39). (2), pp. 296. Clin Res.

Chapleau, M. W. (1991). Types of baroreceptor afferent neurons. Circulation research, 68(2), 619-20. PMID: 1991360.

Hajduczok, G., Chapleau, M. W. & Abboud, F. M. (1991). Increase in sympathetic activity with age. II. Role of impairment of cardiopulmonary baroreflexes. The American journal of physiology, 260(4 Pt 2), H1121-7. PMID: 2012218.

Hajduczok, G., Chapleau, M. W., Johnson, S. L. & Abboud, F. M. (1991). Increase in sympathetic activity with age. I. Role of impairment of arterial baroreflexes. The American journal of physiology, 260(4 Pt 2), H1113-20. PMID: 1901459.

Xie, P. L., McDowell, T. S., Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1991). Rapid baroreceptor resetting in chronic hypertension. Implications for normalization of arterial pressure. Hypertension, 17(1), 72-9. PMID: 1986984.

Li, Z., Chapleau, M. (1991). Aggregated Platelets Release a Factor that Suppresses Baroreceptor Activity. (Vols. 5). (5), pp. 1033. FASEB.

Li, Z., Chapleau, M. (1991). Activated Platelets Release a Stable Diffusible Mediator that Suppresses Baroreceptor Activity. AHA.

Hajduczok, G., Chapleau, M. & Abboud, F. M. (1990). Rapid Adaptation Rather than Impaired Neurons Explain the Suppressed Baroreflex with Aging. Winner: Henry Christian Memorial Award. (Vols. 38). (2), pp. 412. Clin Res.

McDowell, T. S., Chapleau, M., Hajduczok, G. & Abboud, F. M. (1990). Selective Impairment of Parasympathetic Control of Heart Rate in Conscious Diabetic Rabbits. (Vols. 4). (3), pp. 285. FASEB.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1990). Selective Modulation of Dynamic vs. Sustained Baroreceptor Responses by Na+ Pump and A-Current. (Vols. 82). (4), pp. II-9. Circulation.

McDowell, T. S., Chapleau, M., Hajduczok, G. & Abboud, F. M. (1990). Site of Baroreflex Dysfunction in Diabetes. (Vols. 82). (4), pp. III-335. Circulation.

Hajduczok, G., Ferlic, R. J., Chapleau, M. W. & Abboud, F. M. (1990). Mechanism of Mechano-transduction of Arterial Baroreceptors. (Vols. 4). (3), pp. 285. FASEB.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1990). Mechanism of Adaptation of Baroreceptors in Acute Hypertension: Role of A-Current. (Vols. 16). (3), pp. 348. Hypertension.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1990). Central Adaptation of the Baroreflex During Sustained Elevations in Arterial Pressure. International Symposium on SHR.

Xie, P. L., Chapleau, M. W., McDowell, T. S., Hajduczok, G. & Abboud, F. M. (1990). Mechanism of decreased baroreceptor activity in chronic hypertensive rabbits. Role of endogenous prostanoids. The Journal of clinical investigation, 86(2), 625-30. PMID: 2117025.

Hajduczok, G., Chapleau, M. & Abboud, F. M. (1990). Increased Renal Sympathetic Activity with Aging: Role of Arterial and Cardiopulmonary Reflexes. (Vols. 8). (3), pp. 54. Hypertension.

Chapleau, M. W., Johnson, S. L., Hajduczok, G. & Abboud, F. M. (1990). Carotid Sinus Nerve Activity is Flow-Dependent During Static and Pulsatile Pressure. (Vols. 8). (3), pp. 64. Hypertension.

Xie, P., McDowell, T. S., Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1990). Decreased Prostacyclin Production Contributes to Baroreceptor Impairment in Hypertensive Rabbits. International Symposium on SHR.

Chen, H. I., Chapleau, M. W., McDowell, T. S. & Abboud, F. M. (1990). Prostaglandins contribute to activation of baroreceptors in rabbits. Possible paracrine influence of endothelium. Circulation research, 67(6), 1394-404. PMID: 2245501.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1990). Dual Effects of Endothelin on Baroreceptor Activity. (Vols. 82). (4), pp. II-11. Circulation.

Hajduczok, G., Chapleau, M. W. & Abboud, F. M. (1989). Mechanisms of Activation of Arterial Baroreceptors and the Central Integration of Baroreceptor Activity.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Pattern of Baroreceptor Discharge Determines the Magnitude of Inhibition of Sympathetic Nerve Activity. (Vols. 17). pp. 158. Proc Int Union Physiol Sci.

Chapleau, M. W., McDowell, T. S., Hajduczok, G. & Abboud, F. M. (1989). Sensitization of Baroreceptors Following Pulsatile Pressure is Not Caused by Prostacyclin or Other Endothelial Factors. (Vols. 3). (3), pp. 857. FASEB.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Peripheral and central mechanisms of baroreflex resetting. Clinical and experimental pharmacology & physiology. Supplement, 15, 31-43. PMID: 2680188.

Hajduczok, G., Chapleau, M., Johnson, S. L. & Abboud, F. M. (1989). Exercise Training Does Not Restore the Impaired Baroreflex with Age. (Vols. 80). (4), pp. II289. Circulation.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Pulsatile Pressure Attenuates both Baroreceptor and CNS Components of Baroreflex Resetting. (Presented at IUPS Satellite Symposium. (Vols. 136). (584), pp. 8. Acta Physiol Scand.

Hajduczok, G., Chapleau, M. & Abboud, F. M. (1989). Loss of Cardiopulmonary (CP) Inhibition of Baroreflex Function with Age. (Vols. 3). (3), pp. 857. FASEB.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Pulsatile activation of baroreceptors causes central facilitation of baroreflex. The American journal of physiology, 256(6 Pt 2), H1735-41. PMID: 2735443.

McDowell, T. S., Axtelle, T. S., Chapleau, M. W. & Abboud, F. M. (1989). Prostaglandins in carotid sinus enhance baroreflex in rabbits. The American journal of physiology, 257(2 Pt 2), R445-50. PMID: 2504063.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Endothelin Suppresses Baroreceptor Activity: A New Mechanism Contributing to Hypertension. (Vols. 14). (3), pp. 336-337. Hypertension.

Chapleau, M. W., Abboud, F. M. (1989). Determinants of sensitization of carotid baroreceptors by pulsatile pressure in dogs. Circulation research, 65(3), 566-77. PMID: 2766484.

Chapleau, M. W., Johnson, S. L., Hajduczok, G. & Abboud, F. M. (1989). "Rheoreceptors" in the Carotid Sinus are Activated by Flow at Constant Pressure: Interactions Between Flow and Pulsatility. (Vols. 37). (4), pp. 874. Clin Res.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Contrasting Effects of Static and Pulsatile Pressure on Reset¬ting of Baroreceptors and on Central Adaptation of the Baroreflex. IUPS.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Adaptation of Baroreceptors with Elevated Static Arterial Pressure is Absent or Attenuated with Pulsatile Pressure. (Vols. 15). pp. 336. Soc Neurosci Abstr.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1988). New insights into the influence of pulsatile pressure on the arterial baroreceptor reflex. Clinical and experimental hypertension. Part A, Theory and practice, 10 Suppl 1, 179-91. PMID: 3072123.

Xie, P., Chapleau, M., McDowell, T. S. & Abboud, F. M. (1988). Mechanism of Fluctuation of Arterial Pressure in Hypertension - Impaired Resetting of Baroreceptors. (Vols. 36). (3), pp. 547. Clin Res.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1988). Escape of Sympathetic Activity from Baroreflex Inhibition: Critical Role of Adaptation of Central Neurons. (Vols. 36). (6), pp. 862. Clin Res.

Chapleau, M. W., Johnson, S. L., Hajduczok, G. & Abboud, F. M. (1988). Relative Contribution of Pulse Amplitude and Frequency to Post-Pulsatile Pressure Sensitization of Barore¬ceptors. (Vols. 31). (4), pp. 198. The Physiologist.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1988). Phasic Baroreceptor Activity Causes Greater Reflex Sympathetic Inhibition Regardless of Changes in Afferent Activity per Unit Time. (Vols. 2). (4), pp. 718. FASEB.

Abboud, F. M., Chapleau, M. & Hajduczok, G. (1988). Types and Mechanisms of Baroreceptor Resetting. International Society of Hypertension.

McDowell, T. S., Xie, P., Chapleau, M. W. & Abboud, F. M. (1988). Rapid Reversal of Chronic Resetting in Renal Hypertensive Rabbits by Acute Hypotension. (Vols. 2). (5), pp. 1279. FASEB.

Xie, P., McDowell, T. S., Hajduczok, G., Chapleau, M. W. & Abboud, F. M. (1988). Contribution of Cyclooxygenase Metabolites to Baroreceptor Activation in Hypercholesterolemic (HC) Rab¬bits. (Vols. 78). (4), pp. II-177. Circulation.

Chapleau, M. W., Hajduczok, G., Shasby, D. M. & Abboud, F. M. (1988). Activated endothelial cells in culture suppress baroreceptors in the carotid sinus of dog. Hypertension, 11(6 Pt 2), 586-90. PMID: 3134304.

Abboud, F. M., Chapleau, M. W. (1988). Effects of pulse frequency on single-unit baroreceptor activity during sine-wave and natural pulses in dogs. The Journal of physiology, 401, 295-308. PMID: 3171989.

Xie, P., Chapleau, M., McDowell, T. S. & Abboud, F. M. (1988). Cyclooxygenase Metabolites Contribute to Baroreceptor Activation in Normotensive but Not Hypertensive Rabbits. (Vols. 2). (6), pp. 1716. FASEB.

Hajduczok, G., Chapleau, M. W. & Abboud, F. M. (1988). Rheoreceptors in the carotid sinus of dog. Proceedings of the National Academy of Sciences of the United States of America, 85(19), 7399-403. PMID: 3174642.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1988). Mechanisms of resetting of arterial baroreceptors: an overview. The American journal of the medical sciences, 295(4), 327-34. PMID: 2834951.

Xie, P., Chapleau, M., McDowell, T. S., Hajduczok, G. & Abboud, F. M. (1988). Chronic Resetting of Baroreceptors Differs in Hypercholesterolemic vs. Renal Hypertensive Rabbits. (Vols. 31). (4), pp. 198. The Physiologist.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1988). Adaptation of "Central Neurons" Causes Escape of Sympathetic Activity from Baroreflex Inhibition. (Vols. 78). (4), pp. II-543. Circulation.

Chapleau, M. W., Wilson, L. B., Gregory, T. J. & Levitzky, M. G. (1988). Chemoreceptor stimulation interferes with regional hypoxic pulmonary vasoconstriction. Respiration physiology, 71(2), 185-200. PMID: 3340818.

Chapleau, M. W., Hajduczok, G., Brotherton, A. & Abboud, F. M. (1987). Role of Endothelium in Baroreceptor Activation - Acute Effect of Endothelial Denudation. (Vols. 46). (3), pp. 320. Fed Proc.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1987). The Pattern of Baroreceptor Afferent Impulses is More Important than the Number of Impulses per Unit Time in Reflex Inhibi¬tion of Sympathetic Activity. (Vols. 35). (6), pp. 875. Clin Res.

Chen, H. I., Chapleau, M. & Abboud, F. M. (1987). Role of Prostaglandins in "Acute Resetting" of Arterial Baroreceptors. (Vols. 46). (4), pp. 1250. Fed Proc.

Chen, H. I., McDowell, T. S., Chapleau, M. W. & Abboud, F. M. (1987). The Role of Endothelium in Baroreceptor Activation: Endothelial Denudation Suppresses Baroreceptor Activity. (Vols. 76). (4), pp. 348. Circulation.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1987). Endothelial Factors May Alter Baroreceptor Activity. (Vols. 10). (4), pp. 355. Hypertension.

Chapleau, M. W., Abboud, F. M. (1987). Contrasting effects of static and pulsatile pressure on carotid baroreceptor activity in dogs. Circulation research, 61(5), 648-58. PMID: 3664974.

Hajduczok, G., Chapleau, M. & Abboud, F. M. (1987). Differential Effects of Flow on Carotid Sinus Baroreceptor Nerve Activity at Constant Pressures. (Vols. 46). (3), pp. 320. Fed Proc.

Chapleau, M. W., Heesch, C. M. & Abboud, F. M. (1987). Prevention or attenuation of baroreceptor resetting by pulsatility during elevated pressure. Hypertension, 9(6 Pt 2), III137-41. PMID: 3596780.

Hajduczok, G., Chapleau, M. & Abboud, F. M. (1987). Are the Arterial Baroreceptors Sensitive to Change in Flow at a Constant Pressure. (Vols. 35). (3), pp. 284. Clin Res.

Chapleau, M. W., Abboud, F. M. (1986). Sensitization of Baroreceptors Following Pulsatile Pressure is Related to Pulsatile Strain. (Vols. 29). (4), pp. 108. The Physiologist.

Axtelle, T. S., Chapleau, M., McDowell, T. S. & Abboud, F. M. (1986). The Role of Endothelium in Activation of the Arterial Baroreflex. (Vols. 29). (4), pp. 108. The Physiologist.

Chapleau, M. W., Abboud, F. M. (1986). Sensitization of Arterial Baroreceptors by Pulsatile Pressure. (Vols. 8). (9), pp. 831. Hypertension.

Chapleau, M. W., Heesch, C. M. & Abboud, F. M. (1986). Pulsatility may Sensitize Arterial Baroreceptors and Prevent the Phenomenon of "Acute Resetting.". (Vols. 24). (4), pp. 959. Clin Res.

McDowell, T. S., Chapleau, M. & Abboud, F. M. (1986). Arachidonic Acid Enhances Baroreflex Inhibition of Sympathetic Nerve Activity and Heart Rate. (Vols. 34). (2), pp. 482. Clin Res.

Chapleau, M. W., Abboud, F. M. (1986). Mechanisms of Carotid Baroreceptor Stimulation with Static and Dynamic Stretch. (Vols. 16). pp. 43. Proc Int Union Physiol Sci.

Abboud, F. M., Chapleau, M. (1986). "Diastolic Silence" of Carotid Baroreceptors at Pulsatile Pressures Above Threshold - Role of Ionic Mechanisms. (Vols. 45). (3), pp. 296. Fed Proc.

Chapleau, M. W., Abboud, F. M. (1986). Effect of a Change from Static to Pulsatile Pressure on Single and Multiunit Baroreceptor Activity - Unit Recruitment vs. Diastolic Silence. (Vols. 45). (3), pp. 155. Fed Proc.

Axtelle, T. S., Chapleau, M., McDowell, T. S. & Abboud, F. M. (1986). Indomethacin Inhibits Carotid Baroreceptors - Possible Role of Endothelium in Activation of Arterial Baroreceptors. (Vols. 34). (4), pp. 918. Clin Res.

Gregory, T. J., Weinberg, A. B., Chapleau, M. W., Summer, W. R. & Levitzky, M. G. (1985). Sex vs. Age as the Cause of Attenuation of Hypoxic Pulmonary Vasoconstriction in Ferrets. (Vols. 131). pp. 415. Am Rev Resp Dis.

Chapleau, M. W., Wilson, L. B., Gregory, T. J. & Levitzky, M. G. (1985). The Influence of Arterial Chemoreceptor Stimulation on Hypoxic Pulmonary Vasoconstriction. (Vols. 44). (3), pp. 820. Fed Proc.

Chapleau, M. W., Fankhauser, L. J. & Abboud, F. M. (1985). Influence of Pulse Frequency on Single Unit Baroreceptor Discharge. (Vols. 28). (4), pp. 273. The Physiologist.

Hall, S. M., Chapleau, M., Cairo, J. & Levitzky, M. G. (1985). Effect of high-frequency positive-pressure ventilation on halothane ablation of hypoxic pulmonary vasoconstriction. Critical care medicine, 13(8), 641-5. PMID: 3893888.

Chapleau, M. W. (1985). Hypoxic Pulmonary Vasoconstriction in Dogs: Modification by Arterial Chemoreceptor Stimulation and Heartworm Disease.

Chapleau, M. W., Fish, R. E. & Levitzky, M. G. (1985). Regional hypoxic pulmonary vasoconstriction in dogs with asymptomatic dirofilariasis. American journal of veterinary research, 46(6), 1341-5. PMID: 4026011.

Gregory, T. J., Weinberg, A. B., Chapleau, M. W., Summer, W. R. & Levitzky, M. G. (1985). Age Decreases Non-Starling Resistance in Ferret Lungs. (Vols. 44). (5), pp. 1755. Fed Proc.

Gregory, T. J., Chapleau, M., Summer, W. R. & Levitzky, M. G. (1984). The Effects of Aging on Hypoxic Pulmonary Vasoconstriction. (Vols. 27). (4), pp. 263. The Physiologist.

Chapleau, M. W., Gouaux, E. S. & Levitzky, M. G. (1984). The Effect of Carotid Body Chemoreceptor Stimulation on Pulmonary Blood Flow During Unilateral Alveolar Hypoxia. (Vols. 43). (4), pp. 921. Fed Proc.

Chapleau, M. W., Levitzky, M. G. (1984). Canine Heartworms (Dirofilaria immitis) Attenuate Hypoxic Pulmonary Vasoconstriction. (Vols. 27). (4), pp. 263. The Physiologist.

Gregory, T. J., Chapleau, M., Summer, W. R. & Levitzky, M. G. (1984). Aging Attenuates Hypoxic Pulmonary Vasoconstriction in Ferrets. (Vols. 32). (5), pp. 856. Clin Res.

Hall, S. M., Chapleau, M., Cairo, J. & Levitzky, M. G. (1983). The Effect of High Frequency Ventilation on Halothane ablation of Hypoxic Pulmonary Vasoconstriction. (Vols. 42). (4), pp. 595. Fed Proc.