Mark Chapleau | Department of Internal Medicine

Professor of Molecular Physiology and Biophysics
Professor of Internal Medicine - Cardiovascular Medicine

Contact Information

Primary Office
629 Medical Research Center (MRC)
Iowa City, IA 52242
319-335-8958

mark-chapleau@uiowa.edu

Deputy Editor-in-Chief USA, Experimental Physiology (EP) Editorial Board

Education

BS, Biology/Chemistry, University of Wisconsin
PhD, Physiology, Louisiana State University Medical Center

Postdoctoral Fellow, Research, University of Iowa College of Medicine

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Neuroscience

Center, Program and Institute Affiliations

Cardiovascular Research Center, George M. O’Brien Kidney Research Center

Research Summary

Dr. Chapleau's research focuses on mechanisms of autonomic regulation in health and disease including effects of aging, hypertension, hypercholesterolemia, cardiomyopathy, myocardial infarction (MI), heart failure, and muscular dystrophy. Key hypotheses involve the roles of acid-sensing ion channels in sensory transduction, reactive oxygen species and angiotensin in sensory and sympathetic signaling, and oxidative stress in autonomic dysregulation. Experimental approaches include assessment of the cellular and molecular basis of sensory transduction and neuronal excitability in baroreceptor and sympathetic neurons using patch-clamp, imaging, and molecular techniques; recording of baroreceptor and sympathetic nerve activity in vivo; and assessment of cardiovascular and autonomic function in conscious mice using radiotelemetry.

Publications

Chapleau, M. W., Rotella, D. L., Reho, J. J., Rahmouni, K. & Stauss, H. M. (2016). Chronic vagal nerve stimulation prevents high-salt diet-induced endothelial dysfunction and aortic stiffening in stroke-prone spontaneously hypertensive rats. American journal of physiology. Heart and circulatory physiology, 311(1), H276-85. PMID: 27208157.

Sabharwal, R., Rasmussen, L., Sluka, K. A. & Chapleau, M. W. (2016). Exercise prevents development of autonomic dysregulation and hyperalgesia in a mouse model of chronic muscle pain. Pain, 157(2), 387-98. DOI: 10.1097/j.pain.0000000000000330.

Chu, Y., Lund, D. D., Doshi, H., Keen, H. L., Knudtson, K. L., Funk, N. D., Shao, J. Q., Cheng, J., Hajj, G. P., Zimmerman, K. A., Davis, M. K., Brooks, R. M., Chapleau, M. W., Sigmund, C. D., Weiss, R. M. & Heistad, D. D. (2016). Fibrotic Aortic Valve Stenosis in Hypercholesterolemic/Hypertensive Mice. Arterioscler Thromb Vasc Biol. DOI: 10.1161/atvbaha.115.306912.

Sabharwal, R., Weiss, R. M., Zimmerman, K., Domenig, O., Cicha, M. Z. & Chapleau, M. W. (2015). Angiotensin-dependent autonomic dysregulation precedes dilated cardiomyopathy in a mouse model of muscular dystrophy. Experimental Physiology. DOI: 10.1113/EP085066.

Prasad, A. M., Morgan, D. A., Nuno, D. W., Ketsawatsomkron, P., Bair, T. B., Venema, A. N., Dibbern, M. E., Kutschke, W. J., Weiss, R. M., Lamping, K. G., Chapleau, M. W., Sigmund, C. D., Rahmouni, K. & Grumbach, I. M. (2015). Calcium/calmodulin-dependent kinase II inhibition in smooth muscle reduces angiotensin II-induced hypertension by controlling aortic remodeling and baroreceptor function. J Am Heart Assoc, 4(6), e001949. DOI: 10.1161/jaha.115.001949.

Singh, M. V., Cicha, M. Z., Meyerholz, D. K., Chapleau, M. W. & Abboud, F. M. (2015). Dual Activation of TRIF and MyD88 Adaptor Proteins by Angiotensin II Evokes Opposing Effects on Pressure, Cardiac Hypertrophy, and Inflammatory Gene Expression. Hypertension, 66(3), 647-56. DOI: 10.1161/hypertensionaha.115.06011.

Chen, K. H., Anderson, S. W., Grafft, A. & Chapleau, M. W. (2014). Habituation of parasympathetic-mediated heart rate responses to recurring acoustic startle. (Vols. 5). (Article 1288) Frontiers in Psychology.

Santana-Filho, V. J., Davis, G. J., Castania, J. A., Ma, X., Salgado, H. C., Abboud, F. M., Fazan, R. & Chapleau, M. W. (2014). Autocrine/paracrine modulation of baroreceptor activity after antidromic stimulation of aortic depressor nerve in vivo. (Vols. 180). pp. 24-31. Autonomic Neuroscience.

Sabharwal, R., Chapleau, M. W. (2014). Autonomic, locomotor and cardiac abnormalities in a mouse model of muscular dystrophy: targeting the renin-angiotensin system. Exp Physiol, 99(4), 627-31. DOI: 10.1113/expphysiol.2013.074336.

Raven, P. B., Chapleau, M. W. (2014). Blood pressure regulation XI: overview and future research directions. Eur J Appl Physiol, 114(3), 579-86. DOI: 10.1007/s00421-014-2823-z.

Sabharwal, R., Cicha, M. Z., Sinsterra, R. D., de Sousa, F. B., Santos, R. A. & Chapleau, M. W. (2014). Chronic oral administration of Ang-(1-7) improves skeletal muscle, autonomic and locomotor phenotypes in muscular dystrophy. (Vols. 127). pp. 101-109. Clinical Science (London). DOI: 10.1042/CS20130602.

Chapleau, M. W. (2014). Contributions of skeletal muscle myopathy to heart failure: novel mechanisms and therapies. Introduction. Exp Physiol, 99(4), 607-8. DOI: 10.1113/expphysiol.2013.074294.

Singh, M. V., Chapleau, M. W., Harwani, S. C. & Abboud, F. M. (2014). The immune system and hypertension. Immunol Res, 59(1-3), 243-53. DOI: 10.1007/s12026-014-8548-6.

Lu, Y., Whiteis, C. A., Sluka, K. A., Chapleau, M. W. & Abboud, F. M. (2013). Reply from Y. Lu, C. A. Whiteis, K. A. Sluka, M. W. Chapleau and F. M. Abboud. J Physiol, 591(14), 3669. DOI: 10.1113/jphysiol.2013.256453.

Lu, Y., Whiteis, C. A., Sluka, K. A., Chapleau, M. W. & Abboud, F. M. (2013). Responses of glomus cells to hypoxia and acidosis are uncoupled, reciprocal and linked to ASIC3 expression: selectivity of chemosensory transduction. J Physiol, 591(4), 919-32. DOI: 10.1113/jphysiol.2012.247189.

Freeman, R., Chapleau, M. W. (2013). Testing the autonomic nervous system. Handb Clin Neurol, 115, 115-36. DOI: 10.1016/b978-0-444-52902-2.00007-2.

Robertson, D., Diedrich, A. & Chapleau, M. W. (2012). Editorial on arterial baroreflex issue. Auton Neurosci, 172(1-2), 1-3. DOI: 10.1016/j.autneu.2012.10.010.

Harwani, S. C., Chapleau, M. W., Legge, K. L., Ballas, Z. K. & Abboud, F. M. (2012). Neurohormonal modulation of the innate immune system is proinflammatory in the prehypertensive spontaneously hypertensive rat, a genetic model of essential hypertension. Circ Res, 111(9), 1190-7. DOI: 10.1161/circresaha.112.277475.

Chapleau, M. W., Sabharwal, R. (2011). Methods of assessing vagus nerve activity and reflexes. Heart failure reviews, 16(2), 109-27. PMID: 20577901.

Harwani, S. C., Chapleau, M. & Abboud, F. M. (2011). Abnormal autonomic regulation of the immune system in genetic hypertension. (Vols. 25). pp. 640.34. FASEB.

Freeman, R., Chapleau, M. W. (2011). Assessment of Cardiovascular Autonomic Function.

Harwani, S. C., Chapleau, M., Legge, K., Ballas, Z. & Abboud, F. M. (2011). Autonomic dysregulation of innate immunity in genetic hypertension. Hypertension.

Kaufmann, H., Chapleau, M. W. (2011). Cardiovascular Regulation.

Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2011). Expression of miRNAs targeting genes controlling baroreceptor sensory transduction differs in SHR vs. WKY rats. (Vols. 25). pp. 606. FASEB.

Lu, Y., Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2011). Functional and molecular defects of baroreceptor neurons in genetic hypertension. (Vols. 23). J Physiol Proc Physiol Soc.

Weiss, R. M., Sabharwal, R., Zimmerman, K. & Chapleau, M. W. (2011). Hypercholesterolemia and angiotensin-mediated hypertension act synergistically to produce aortic stenosis in middle-aged mice. (Vols. 25). pp. 641.12. FASEB.

Sabharwal, R., Abboud, F. M. & Chapleau, M. W. (2011). Methionine sulfoxide reductase-A is required for normal baroreflex sensitivity and sympathovagal balance: evidence for redox regulation of autonomic function in young mice. (Vols. 21). pp. 218-219. Clin Autonom Res.

Sabharwal, R., Abboud, F. M., Russo, A. F. & Chapleau, M. W. (2011). Nervous system-targeted expression of CGRP/RAMP1 receptors enhances baroreflexes and opposes angiotensin-induced hypertension. (Vols. 23). pp. 101. J Physiol Proc Physiol Soc.

Wang, R., Whiteis, C. A., Benson, C. J., Chapleau, M. W. & Abboud, F. M. (2011). pH sensitivity of nodose ganglia neurons: Evidence for a pH conditioned Cl? conductance. Hypertension.

Sabharwal, R., Abboud, F. M., Russo, A. F. & Chapleau, M. W. (2011). Transgenic expression of CGRP receptor subunit RAMP1 in nervous system improves autonomic regulation and prevents angiotensin II hypertension. (Vols. 25). pp. 661.3. FASEB.

Lataro, R. M., Castania, J. A., Chapleau, M. W., Salgado, H. C. & Fazan, R. (2010). Baroreceptor and chemoreceptor contributions to the hypertensive response to bilateral carotid occlusion in conscious mice. American journal of physiology. Heart and circulatory physiology, 299(6), H1990-5. PMID: 20852042.

Chapleau, M. W. (2010). CIH: from sleep apnea to breath-hold diving. Is sympathetic activation inevitable?. Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 20(2), 53-5. PMID: 20405161.

Sabharwal, R., Zhang, Z., Lu, Y., Abboud, F. M., Russo, A. F. & Chapleau, M. W. (2010). Receptor activity-modifying protein 1 increases baroreflex sensitivity and attenuates Angiotensin-induced hypertension. Hypertension, 55(3), 627-35. PMID: 20100989.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Simms, A. E., Paton, J. F., Chapleau, M. W. & Abboud, F. M. (2010). Chemoreceptor hypersensitivity, sympathetic excitation, and overexpression of ASIC and TASK channels before the onset of hypertension in SHR. Circulation research, 106(3), 536-45. PMID: 20019330.

Sabharwal, R., Weiss, R. M., Zimmerman, K. & Chapleau, M. W. (2010). Angiotensin II contributes to skeletal muscle fibrosis, reduced locomotor activity and autonomic dysfunction in ?-sarcoglycan deficient mice with muscular dystrophy. (Vols. 56). (5), pp. 301. Hypertension.

Flanagan, D. W., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2010). Angiotensin II-induced reactive oxygen species signaling in sympathetic ganglia. (Vols. 20). (5), pp. 321. Clin Autonom Res.

Sabharwal, R., Morgan, D. A., Whiteis, C. A., Rahmouni, K., Chapleau, M. W. & Abboud, F. M. (2010). ASIC2 dependent activation of the baroreceptors is required for the arterial baroreflex. (Vols. 24). pp. 625.1. FASEB.

Sabharwal, R., Weiss, R. M., Zimmerman, K. & Chapleau, M. W. (2010). Autonomic dysregulation precedes and predicts cardiac dysfunction and mortality in a mouse model of muscular dystrophy. (Vols. 20). (5), pp. 300. Clin Autonom Res.

Peotta, V. A., Weiss, R. M., Zimmerman, K., Lu, Y., Russo, A. F., Abboud, F. M. & Chapleau, M. W. (2010). Consequences of enhanced CGRP receptor signaling on cardiac function and mortality post-myocardial infarction. (Vols. 24). pp. 1037.4. FASEB.

Sabharwal, R., Weiss, R. M., Zimmerman, K. & Chapleau, M. W. (2010). Differential sympathetic activation and blunted cardiovascular diurnal rhythms in a mouse model of hypertrophic cardiomyopathy. (Vols. 24). pp. 809.17. FASEB.

Sabharwal, R., Weiss, R. M. & Chapleau, M. W. (2010). Dysautonomia precedes cardiomyopathy in a mouse model of muscular dystrophy. (Vols. 51-52). pp. 51-52. Clin Autonom Res.

Lu, Y., Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2010). Molecular and functional phenotyping of baroreceptor neurons in spontaneously hypertensive rats. (Vols. 56). (5), pp. 108-109. Hypertension.

Lu, Y., Whiteis, C. A., Chapleau, M. W., Sluka, K. & Abboud, F. M. (2010). Sensitivity to low pH in mouse glomus type 1 cells correlates with ASIC3 expression. (Vols. 24). pp. 691. FASEB.

Lu, Y., Ma, X., Sabharwal, R., Snitsarev, V., Morgan, D., Rahmouni, K., Drummond, H. A., Whiteis, C. A., Costa, V., Price, M., Benson, C., Welsh, M. J., Chapleau, M. W. & Abboud, F. M. (2009). The ion channel ASIC2 is required for baroreceptor and autonomic control of the circulation. Neuron, 64(6), 885-97. PMID: 20064394.

Roghair, R. D., Segar, J. L., Volk, K. A., Chapleau, M. W., Dallas, L. M., Sorenson, A. R., Scholz, T. D. & Lamb, F. S. (2009). Vascular nitric oxide and superoxide anion contribute to sex-specific programmed cardiovascular physiology in mice. American journal of physiology. Regulatory, integrative and comparative physiology, 296(3), R651-62. PMID: 19144750.

Sabharwal, R., Allen, J. E., Ziemann, A. E., Welsh, M. J., Wemmie, J. A. & Chapleau, M. W. (2009). Acid-sensing ion channel-1a contributes to fear-evoked behavioral and cardiovascular responses.

Sabharwal, R., Weiss, R. M. & Chapleau, M. W. (2009). Autonomic dysregulation in a mouse model of muscular dystrophy destined to develop dilated cardiomyopathy. (Vols. 23). pp. 1008.11. FASEB.

Fazan, R., Lu, Y. & Chapleau, M. W. (2009). CGRP selectively activates a subpopulation of nodose sensory neurons with tonic action potential firing properties. (Vols. 23). pp. 1008.16. FASEB.

Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2009). Differential sensitivity of carotid body glomus cells to hypoxia and acidosis. (Vols. 23). pp. 1002.2. FASEB.

Sabharwal, R., Weiss, R. M. & Chapleau, M. W. (2009). Dysautonomia precedes cardiomyopathy in a mouse model of muscular dystrophy. (Vols. 149). pp. 89-90. Autonomic Neuroscience.

Santana-Filho, V. J., Abboud, F. M. & Chapleau, M. W. (2009). Hydrogen peroxide mediates post-excitatory depression of baroreceptor afferent activity in vivo. (Vols. 23). pp. 1008.15. FASEB.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2009). Inhibition of TASK currents contributes to enhanced pH sensitivity of chemoreceptors in prehypertensive SHR. (Vols. 120). pp. 1160. Circulation.

Fazan, V. P., Santana Filho, V. J., Fazan, R., Salgado, H. C., Moore, K. C. & Chapleau, M. W. (2009). Morphological differences in aortic depressor nerves of rats and mice: Implications for understanding the molecular/structural basis of baroreceptor function. (Vols. 14). pp. 46. Peripheral Nervous System.

Sabharwal, R., Weiss, R. M., Zimmerman, K. & Chapleau, M. W. (2009). Severe autonomic dysregulation in tropomyosin mutant mice: A possible contributor to arrhythmias and sudden death in hypertrophic cardiomyopathy. (Vols. 54). (4), pp. 85-86. Hypertension.

Lin, M., Ai, J., Li, L., Huang, C., Chapleau, M. W., Liu, R., Gozal, D., Wead, W. B., Wurster, R. D. & Cheng, Z. '. (2008). Structural remodeling of nucleus ambiguus projections to cardiac ganglia following chronic intermittent hypoxia in C57BL/6J mice. The Journal of comparative neurology, 509(1), 103-17. PMID: 18425809.

Ziemann, A. E., Sabharwal, R., Welsh, M. J., Chapleau, M. W. & Wemmie, J. A. (2008). Acid-sensing ion channel-1a (ASIC1a) contributes to fear and associated autonomic/cardiovascular responses. (Vols. 22). pp. 946.8. FASEB.

Sabharwal, R., Wemmie, J. A., Abboud, F. M. & Chapleau, M. W. (2008). Acid-sensing ion channel-1a differentially contributes to blood pressure and heart rate responses to hypoxia and hypercapnia. (Vols. 22). pp. 739.5. FASEB.

Chapleau, M. W. (2008). Arterial Baroreflexes.

Sabharwal, R., Wemmie, J. A., Abboud, F. M. & Chapleau, M. W. (2008). Contrasting autonomic and cardiovascular phenotypes in ASIC1a and ASIC2 deficient mice. (Vols. 22). pp. 953.11. FASEB.

Lataro, R. M., Castania, J. A., Chapleau, M. W., Salgado, H. C. & Fazan, R. (2008). Contributions of baro- and chemoreceptors in mediating the hypertensive response to bilateral carotid occlusion in conscious mice. (Vols. 22). pp. 739.8. FASEB.

Sabharwal, R., Zhang, H. J., Stauss, H. M., Abboud, F. M., Russo, A. F. & Chapleau, M. W. (2008). Enhancement of CGRP receptor signaling: A novel approach to improving autonomic regulation in normal and hypertensive states. (Vols. 18). (5), pp. 252-253. Clin Autonom Res.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2008). Molecular basis for hypersensitivity of chemoreceptor reflexes in spontaneously hypertensive rats (SHRs). (Vols. 52). (4), pp. 44. Hypertension.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2008). Molecular substrates of carotid body chemoreceptor activation. (Vols. 118). (18), pp. 360. Circulation.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2008). pH sensitive ion channels contribute to carotid body hypersensitivity in spontaneously hypertensive rats. (Vols. 18). (5), pp. 243. Clin Autonom Res.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2008). Selective sensitization of transduction pathways in carotid body glomus cells of spontaneously hypertensive rats. (Vols. 23). pp. 1002.4. FASEB.

Lu, Y., Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2008). Single cell RT-PCR indicates lower ASIC2a mRNA expression in aortic baroreceptor neurons of adult SHR vs. WKY rats. (Vols. 22). pp. 953.6. FASEB.

Sabharwal, R., Zhang, H. J., Stauss, H. M., Abboud, F. M., Russo, A. F. & Chapleau, M. W. (2008). Transgenic enhancement of CGRP signaling abrogates deleterious effects of angiotensin II on heart rate and blood pressure variability. (Vols. 52). (4), pp. 65. Hypertension.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Benson, C. J., Chapleau, M. W. & Abboud, F. M. (2007). Acid-sensing ion channels contribute to transduction of extracellular acidosis in rat carotid body glomus cells. Circulation research, 101(10), 1009-19. PMID: 17872465.

Gu, H., Lin, M., Liu, J., Gozal, D., Scrogin, K. E., Wurster, R., Chapleau, M. W., Ma, X. & Cheng, Z. J. (2007). Selective impairment of central mediation of baroreflex in anesthetized young adult Fischer 344 rats after chronic intermittent hypoxia. American journal of physiology. Heart and circulatory physiology, 293(5), H2809-18. PMID: 17693540.

Chapleau, M. W. (2007). The continuing saga of neuronal oxidative stress in hypertension: Nox, Nox who's there, and where?. Hypertension, 50(4), 600-2. PMID: 17698720.

Ai, J., Gozal, D., Li, L., Wead, W. B., Chapleau, M. W., Wurster, R., Yang, B., Li, H., Liu, R. & Cheng, Z. (2007). Degeneration of vagal efferent axons and terminals in cardiac ganglia of aged rats. The Journal of comparative neurology, 504(1), 74-88. PMID: 17614301.

Lin, M., Liu, R., Gozal, D., Wead, W. B., Chapleau, M. W., Wurster, R. & Cheng, Z. J. (2007). Chronic intermittent hypoxia impairs baroreflex control of heart rate but enhances heart rate responses to vagal efferent stimulation in anesthetized mice. American journal of physiology. Heart and circulatory physiology, 293(2), H997-1006. PMID: 17384123.

Chapleau, M. W. (2007). Exciting times in sensory transduction from A(drian) to Z. The Journal of physiology, 582(Pt 1), 13-4. PMID: 17463034.

Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2007). Mechano- and chemosensitivity of rat nodose neurones--selective excitatory effects of prostacyclin. The Journal of physiology, 582(Pt 1), 177-94. PMID: 17478531.

Sabharwal, R., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Davisson, R. L., Price, M. P., Welsh, M. J., Abboud, F. M. & Chapleau, M. W. (2007). Abnormalities in baroreflex sensitivity and autonomic control in conscious ASIC2?/? mice. International Conference on Cardiopulmonary Regulation in Health Disease.

Tan, Z. Y., Lu, Y., Whiteis, C. A., Benson, C. J., Chapleau, M. W. & Abboud, F. M. (2007). Acid-sensing ion channels (ASICs) contribute to transduction of extracellular acidosis in rat carotid body glomus cells. Circulation.

Sabharwal, R., Weiss, R. M., Stauss, H. M., Sigmund, C. D., Abboud, F. M. & Chapleau, M. W. (2007). ApoE?/?R+A+ mice with hypercholesterolemia, hypertension, and decreased baroreflex sensitivity spontaneously develop heart failure with age. (Vols. 21). (6), pp. 893. FASEB.

Snitsarev, V., Costa-Bartlett, V., Petroff, E., Whiteis, C. A., Lu, Y., Chapleau, M. W., Welsh, M. J. & Abboud, F. M. (2007). ASIC2 expression is an important determinant of mechanotransduction in nodose neurons. Circulation.

Peotta, V. A., Weiss, R. M., Sabharwal, R., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2007). Associations between cardiac dysfunction and decreased baroreflex sensitivity post-myocardial infarction in mice. pp. 45. Hypertension.

Sabharwal, R., Weiss, R. M., Stauss, H. M., Sigmund, C. D. & Abboud, F. M. (2007). Autonomic and cardiovascular dysfunction in ApoE?/?R+A+ mice with chronic congestive heart failure. pp. 42. Hypertension.

Sabharwal, R., Weiss, R. M., Stauss, H. M., Sigmund, C. D., Abboud, F. M. & Chapleau, M. W. (2007). Autonomic/baroreflex phenotypes in a novel mouse model of spontaneous congestive heart failure. (Vols. 17). (5), pp. 264. Clin Autonom Res.

Salgado, H. C., Barale, A. R., Castania, J. A., Machado, B. H., Chapleau, M. W. & Fazan, R. (2007). Baroreflex responses to electrical stimulation of aortic depressor nerve in conscious SHR. American journal of physiology. Heart and circulatory physiology, 292(1), H593-600. PMID: 16951050.

Lu, Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2007). Decreased mRNA expression of ASIC2a in nodose sensory ganglia is associated with development of hypertension in SHR. (Vols. 21). (6), pp. 1405. FASEB.

Santana-Filho, V. J., Castania, J. A., Salgado, H. C., Chapleau, M. W. & Fazan, R. (2007). Endogenous cyclooxygenase metabolites limit post-excitatory depression of aortic baroreceptor activity in rats. pp. 36. Hypertension.

Gu, H., Lin, M., Gozal, D., Scrogin, K. E., Chapleau, M. W. & Cheng, Z. (2007). Functional changes in afferent, central, and efferent components of the arterial baroreflex circuitry in F344 rats following chronic intermittent hypoxia. (Vols. 21). (6), pp. 823. FASEB.

Mulvaney, J. M., Brooks, V. L., Roberts, D., Chapleau, M. W. & Goldman, R. K. (2007). Gain of baroreflex control of heart rate decreases during late pregnancy in rats. (Vols. 21). (5), pp. 512. FASEB.

Sabharwal, R., Zhang, H. J., Abboud, F. M., Russo, A. F. & Chapleau, M. W. (2007). Genetic enhancement of CGRP receptor signaling increases baroreflex sensitivity and attenuates angiotensin-dependent hypertension. (Vols. 50). (4), pp. 86. Hypertension.

Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2007). M-current in nodose sensory neurons mediates the depolarizing effect of prostacyclin. (Vols. 21). (6), pp. 1407. FASEB.

Chapleau, M. W., Lu, Y. & Abboud, F. M. (2007). Mechanosensitive Ion Channels in Blood-Pressure-Sensing Baroreceptor Neurons.

Abboud, F. M., Lu, Y. & Chapleau, M. W. (2007). Molecular Components of Neural Sensory Transduction: DEG/ENaC Proteins in Baro- and Chemoreceptors.

Snitsarev, V., Tan, Z. Y., Lu, Y., Sabharwal, R., Chapleau, M. W. & Abboud, F. M. (2007). Molecular mechanisms of reciprocal dysautonomia. (Vols. 17). (5), pp. 264. Clin Autonom Res.

Tan, Z. Y., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2007). pH sensitivity of carotid body glomus cells is augmented in spontaneously hypertensive rats. (Vols. 21). (6), pp. 1407. FASEB.

Morris, M., Jones, T. D., Rocha, M. J., Fazan, R., Chapleau, M. W., Salgado, H. C., Johnson, A. K., Irigoyen, M. C., Michelini, L. C. & Goldstein, D. L. (2006). International student exchange and the medical curriculum: evaluation of a medical sciences translational physiology course in Brazil. Advances in physiology education, 30(3), 119-23. PMID: 16912146.

Stauss, H. M., Moffitt, J. A., Chapleau, M. W., Abboud, F. M. & Johnson, A. K. (2006). Baroreceptor reflex sensitivity estimated by the sequence technique is reliable in rats. American journal of physiology. Heart and circulatory physiology, 291(1), H482-3. PMID: 16772526.

Ma, X., Zhang, H. J., Whiteis, C. A., Tian, X., Davisson, R. L., Kregel, K. C., Abboud, F. M. & Chapleau, M. W. (2006). NAD(P)H oxidase-induced oxidative stress in sympathetic ganglia of apolipoprotein E deficient mice. Autonomic neuroscience : basic & clinical, 126-127, 285-91. PMID: 16584925.

Ma, X., Bielefeldt, K., Tan, Z. Y., Whiteis, C. A., Snitsarev, V., Abboud, F. M. & Chapleau, M. W. (2006). Dual mechanisms of angiotensin-induced activation of mouse sympathetic neurones. The Journal of physiology, 573(Pt 1), 45-63. PMID: 16543267.

Sabharwal, R., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Davisson, R. L., Price, M. P., Welsh, M. J., Abboud, F. M. & Chapleau, M. W. (2006). Abnormalities in baroreflex sensitivity and autonomic control in conscious ASIC2?/? mice. (Vols. 20). (5), pp. 1186. FASEB.

Peotta, V. A., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Sabharwal, R., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2006). Aging-induced abnormalities in baroreflex and feed-forward control of heart rate at rest and during spontaneous activity in mice. (Vols. 20). (5), pp. 1209. FASEB.

Ma, X. Y., Tan, Z. Y., Tian, X., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2006). Angiotensin-dependent oxidative stress in sympathetic ganglia causes sympathoexcitation in apoE-/- mice. (Vols. 16). (5), pp. 330. Clin Autonom Res.

Ma, X. Y., Tian, X., Abboud, F. M. & Chapleau, M. W. (2006). Angiotensin-dependent upregulation of AT1 receptors increases NADPH oxidase expression in sympathetic ganglia of atherosclerotic mice. (Vols. 20). (5), pp. 1208. FASEB.

Sabharwal, R., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Price, M. P., Welsh, M. J., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2006). ASIC2-/- mice: A genetic model of impaired baroreceptor activation and neurogenic hypertension. (Vols. 16). (5), pp. 328. Clin Autonom Res.

Sabharwal, R., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Price, M. P., Welsh, M. J., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2006). ASIC2-/- mice: A genetic model of impaired baroreceptor activation and oxidative stress-dependent neurogenic hypertension. Circulation.

Sabharwal, R., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Price, M. P., Welsh, M. J., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2006). ASIC2-/- mice: A genetic model of impaired baroreceptor activation and oxidative stress-dependent neurogenic hypertension. (Vols. 48). (4), pp. 31. Hypertension.

Lu, Y., Whiteis, C. A., Tan, Z. Y., Chapleau, M. W. & Abboud, F. M. (2006). Differential expression of acid-sensing ion channel (ASIC) subunits in rat carotid body. (Vols. 20). (5), pp. 1230. FASEB.

Lu, Y., Whiteis, C. A., Benson, C. J., Chapleau, M. W. & Abboud, F. M. (2006). Expression and localization of acid-sensing ion channels in mouse nodose ganglia. (Vols. 20). (4), pp. 775. FASEB.

Peotta, V. A., Sabharwal, R., Stauss, H. M., Lazartigues, E., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2006). Gender differences in baroreflex sensitivity and lifespan in renin-angiotensinogen transgenic hypertensive mice. (Vols. 48). (4), pp. 46. Hypertension.

Tan, Z. Y., Whiteis, C. A., Lu, Y., Chapleau, M. W. & Abboud, F. M. (2006). Role of BK and ASIC in the activation of glomus cells by extracellular acidosis and hypoxia. (Vols. 20). (5), pp. 1230. FASEB.

Ma, X. Y., Tan, Z. Y., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2006). Sympathetic neurons isolated from apolipoprotein E deficient mice exhibit increased excitability: Role of oxidative stress. (Vols. 48). (4), pp. 35. Hypertension.

Santos, C. M., Chapleau, M., Young, M. E. & Michelini, L. (2006). The role of angiotensin II in isoproterenol-induced cardiomyocyte hypertrophy in mice. Brazilian Physiological Society.

Fazan, R., de Oliveira, M., da Silva, V. J., Joaquim, L. F., Montano, N., Porta, A., Chapleau, M. W. & Salgado, H. C. (2005). Frequency-dependent baroreflex modulation of blood pressure and heart rate variability in conscious mice. American journal of physiology. Heart and circulatory physiology, 289(5), H1968-75. PMID: 15951338.

Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2005). Neuronal prostacyclin is an autocrine regulator of arterial baroreceptor activity. Hypertension, 46(3), 540-6. PMID: 16061731.

Chapleau, M. W. (2005). Predicting cardiovascular risk--the madness is in the methods. Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 15(1), 10-2. PMID: 15768195.

Lazartigues, E., Stauss, H. M., Yerke, M., Whiteis, C. A., Davisson, R. L., Sigmund, C. D., Abboud, F. M. & Chapleau, M. W. (2005). A Novel Mouse Model of Hypertension and Hypercholesterolemia with Reduced Life Span and Baroreflex Impairment. Hypertension.

Stauss, H. M., Lazartigues, E., Habib, A., Whiteis, C. A., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2005). Abnormalities in Baroreflex and Feed-Forward Control of Heart Rate in Conscious Hypertensive and Hypercholesterolemic Mice. (Vols. 46). (4), pp. 816. Hypertension.

Santos, C. M., Chapleau, M. & Michelini, L. C. (2005). Angiotensin II Contributes to Isoproterenol-induced Cardiomyocyte Hypertrophy in Normotensive Mice. FASEB.

Morris, M., Michelini, L., Irigoyen, M. C., Chapleau, M. W., Johnson, A. K., Goldstein, D., Beckley, C. & Farah, V. D. (2005). Biomedical Research as a Key to International Education.

Maheshwari, N., Lazartigues, E., Whiteis, C. A., Yerke, M., Davisson, R. L., Sigmund, C. D. & Chapleau, M. W. (2005). Cardiovascular Dysregulation and Reduced Lifespan in a Novel Mouse Model of Hypertension and Hypercholesterolemia. (Vols. 15). (5), pp. 322. Clin Autonom Res.

Lin, M., Chapleau, M., Liu, R., Gozal, D. & Cheng, Z. (2005). Chronic Intermittent Hypoxia Impairs Baroreflex Control of Heart Rate Despite Enhanced Heart Rate Response to Vagal Stimulation in Mice. Soc Neurosci Abstr.

Salgado, H., Rocha, M., Fazan, R., Michelini, L., Irigoyen, M. C., Chapleau, M. W., Johnson, A. K., Goldstein, D., Sulentic, C., Jones, D. & Beckley, C. (2005). Developing a Global Curriculum for the Medical Sciences.

Ma, X. Y., Tian, X., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2005). Increased Expression of NADPH Oxidase in Sympathetic Ganglia of Atherosclerotic Mice. (Vols. 119). pp. 133. Basic and Clinical.

Sabharwal, R., Chapleau, M., Price, M. P., Welsh, M. J. & Abboud, F. M. (2005). Molecular Mechanisms of Baro- and Chemoreceptor Activation: Evidence that ASIC1 and ASIC3 Contribute to Chemoreceptor Activation. (Vols. 112). (17), pp. II-156. Circulation.

Snitsarev, V., Iyer, K. S., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2005). Novel Molecular Defects in Mechanosensitivity of Aortic Baroreceptor Neurons from Spontaneously Hypertensive Rats. (Vols. 19). (4), pp. 607. FASEB.

Snitsarev, V., Iyer, K. S., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2005). Potassium Channel Defects Contribute to Decreased Excitability of Nodose Neurons in Spontaneously Hypertensive Rats. (Vols. 19). (4), pp. 606. FASEB.

Sabharwal, R., Chapleau, M., Price, M. P., Welsh, M. J. & Abboud, F. M. (2005). Subunits of Acid-sensing Ion Channels (ASICs) Differentially Mediate Baroreceptor and Chemoreceptor Reflexes. (Vols. 19). (5), pp. 1617-1618. FASEB.

Sakai, K., Chapleau, M. W., Morimoto, S., Cassell, M. D. & Sigmund, C. D. (2004). Differential modulation of baroreflex control of heart rate by neuron- vs. glia-derived angiotensin II. Physiological genomics, 20(1), 66-72. PMID: 15467015.

Chapleau, M. W. (2004). Modulation of baroreflex function by altering inspiratory impedance: potential mechanisms and clinical implications. Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 14(4), 217-9. PMID: 15316837.

Ma, X., Sigmund, C. D., Hingtgen, S. D., Tian, X., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2004). Ganglionic action of angiotensin contributes to sympathetic activity in renin-angiotensinogen transgenic mice. Hypertension, 43(2), 312-6. PMID: 14699002.

Snitsarev, V., Yermolaieva, O., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2004). Activity-dependent Resetting of Baroreceptor and Vagal Afferent Neurons Mediated by Endogenous Generation of Hydrogen Peroxide/Hydroxyl Radical. (Vols. 43). (6), pp. 1349. Hypertension.

Snitsarev, V., Yermolaieva, O., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2004). Activity-dependent Resetting of Baroreceptor and Vagal Afferent Neurons Mediated by Hydrogen Peroxide/Hydroxyl Radical. Iowa Physiological Society Meeting.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2004). Differential Expression of Transient K+ Current and Its Inhibition by Angiotensin in Tonic and Phasic Sympathetic Neurons. Exp Biol.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2004). Differential Expression of Transient K? Current (IA) in Tonic and Phasic Sympathetic Neurons and Its Inhibition by Angiotensin. FASEB.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2004). Differential Expression of Transient K? Current and Its Inhibition by Angiotensin in Tonic and Phasic Sympathetic Neurons. Exp Biol.

Lazartigues, E., Whiteis, C. A., Maheshwari, N., Abboud, F. M., Stauss, H. M., Davisson, R. L. & Chapleau, M. W. (2004). Effects of Hypercholesterolemia, Hypertension, and their Interaction on Baroreflex Sensitivity and Cardiac Autonomic Tone: Role of Oxidative Stress. FASEB.

Snitsarev, V., Yermolaieva, O., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2004). Hydrogen Peroxide/Hydroxyl Radical Generated during Action Potential Firing Inhibits Membrane Excitability of Baroreceptor and Vagal Afferent Neurons. (Vols. 14). (5), pp. 304. Clin Autonom Res.

Lazartigues, E., Whiteis, C. A., Maheshwari, N., Abboud, F. M., Stauss, H. M., Davisson, R. L. & Chapleau, M. W. (2004). Oxidative Stress Contributes to Increased Sympathetic Vasomotor Tone and Decreased Baroreflex Sensitivity in Hypertensive and Hypercholesterolemic Mice. (Vols. 18). (4), pp. 299. FASEB.

Ma, X. Y., Zhang, H. J., Whiteis, C. A., Kregel, K. C., Abboud, F. M. & Chapleau, M. W. (2004). Oxidative Stress in Sympathetic Ganglia: A Possible Mechanism of Increased Sympathetic Nerve Activity and Impaired Baroreflex Sensitivity in Atherosclerosis. (Vols. 44). (4), pp. 523. Hypertension.

Maheshwari, N., Lazartigues, E., Whiteis, C. A., Stauss, H. M., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2004). Partial Reversal of Baroreflex and Autonomic Dysfunction in Old Mice by Short-Duration (1-week) Antioxidant Therapy. Iowa Physiological Society Meeting.

Snitsarev, V., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2004). Prostacyclin is an Autocrine Regulator of Excitability and Resetting of Baroreceptor Neurons. (Vols. 44). (4), pp. 524. Hypertension.

Lazartigues, E., Maheshwari, N., Whiteis, C. A., Stauss, H. M., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2004). Restoration of Baroreflex Sensitivity and Cardiovagal Tone in Old Mice by Short-duration Antioxidant Therapy. (Vols. 14). (5), pp. 339. Clin Autonom Res.

Stauss, H. M., Lazartigues, E., Sabharwal, R., Whiteis, C. A., Maheshwari, N., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2004). Role of Baroreflex in Short and Long-term Blood Pressure Regulation Assessed in Conscious Genetically-modified Mice.

Ma, X. Y., Sigmund, C. D., Hingtgen, S. D., Tian, X., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2004). Significant Contribution of a Ganglionic Action of Endogenous Angiotensin to Sympathetic Nerve Activity in Renin-Angiotensinogen Double Transgenic Mice. Iowa Physiological Society Meeting.

Chapleau, M. W., Abboud, F. M. (2004). The Baroreceptor Reflex: Novel Methods and Mechanisms.

Ma, X., Abboud, F. M. & Chapleau, M. W. (2003). Neurocardiovascular regulation in mice: experimental approaches and novel findings. Clinical and experimental pharmacology & physiology, 30(11), 885-93. PMID: 14678254.

Chapleau, M. W. (2003). Determinants of baroreflex sensitivity in health and disease: from correlates to causality. Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 13(5), 310-3. PMID: 14564651.

Meyrelles, S. S., Sharma, R. V., Mao, H. Z., Abboud, F. M. & Chapleau, M. W. (2003). Modulation of baroreceptor activity by gene transfer of nitric oxide synthase to carotid sinus adventitia. American journal of physiology. Regulatory, integrative and comparative physiology, 284(5), R1190-8. PMID: 12676743.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2003). Activity-dependent Resetting of Baroreceptor Neurons in Culture: Role of Mechanosensitive vs. Voltage-gated Ion Channels. Iowa Physiological Society Meeting.

Fazan, R., de Oliveira, M., Dias da Silva, V. J., Chapleau, M. W. & Salgado, H. C. (2003). Blood Pressure and Heart Rate Variability Spectra in Conscious Sinoaortic Denervated C57Bl Mice. (Vols. 17). (5), pp. 1230. FASEB.

Fazan, R., de Oliveira, M., Dias da Silva, V. J., Chapleau, M. W. & Salgado, H. C. (2003). Effect of Autonomic Blockage on Arterial Pressure and Pulse Interval Variability in Conscious Mice. Hypertension.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2003). Enhancement of Excitability of Tonic and Phasic Sympathetic Neurons by Angiotensin. (Vols. 17). (5), pp. 1294. FASEB.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2003). Enhancement of Excitability of Tonic and Phasic Sympathetic Neurons by Angiotensin. Iowa Physiological Society Meeting.

Ma, X. Y., Whiteis, C. A., Sigmund, C. D., Bielefeldt, K., Abboud, F. M. & Chapleau, M. W. (2003). Ganglionic Actions of Angiotensin Increase Sympathetic Nerve Activity: Contribution to Sympathoexcitation in Hypertension and Cellular Mechanisms. (Vols. 13). pp. 362. Clin Autonom Res.

Snitsarev, V., Yermolaieva, O., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2003). Modulation of Sensory Neuron Excitability by Endogenous ROS and Autocrine Factors. (Vols. 108). (17), pp. IV-57. Circulation.

Snitsarev, V., Sullivan, M. J., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (2003). Molecular Basis of Mechanotransduction in Baroreceptor Neurons: Roles of Calcium-activated K? Current (IKca) and Actin. (Vols. 108). (17), pp. IV-57. Circulation.

Sakai, K., Morimoto, S., Chapleau, M. W. & Sigmund, C. D. (2003). Neuron- vs. Glia-derived Angiotensin II Differentially Modulate Baroreflex Control of Heart Rate in Conscious Transgenic Mice. Hypertension.

Sakai, K., Chapleau, M. & Sigmund, C. D. (2003). Neuron-derived Angiotensin Causes Cardiac-Sympathetic Baroreflex Resetting in the Absence of Hypertension. (Vols. 42). (3), pp. 398. Hypertension.

Ma, X. Y., Sigmund, C. D., Hingtgen, S. D., Tian, X., Davisson, R. L., Abboud, F. M. & Chapleau, M. W. (2003). Significant Contribution of a Ganglionic Action of Endogenous Angiotensin to Sympathetic Nerve Activity in Renin-Angiotensinogen Double Transgenic Mice. (Vols. 42). (3), pp. 408. Hypertension.

Fazan, V. P., Ma, X., Chapleau, M. W. & Barreira, A. A. (2002). Qualitative and quantitative morphology of renal nerves in C57BL/6J mice. The Anatomical record, 268(4), 399-404. PMID: 12420288.

Ma, X., Abboud, F. M. & Chapleau, M. W. (2002). Analysis of afferent, central, and efferent components of the baroreceptor reflex in mice. American journal of physiology. Regulatory, integrative and comparative physiology, 283(5), R1033-40. PMID: 12376395.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Mechanosensory transduction of vagal and baroreceptor afferents revealed by study of isolated nodose neurons in culture. Autonomic neuroscience : basic & clinical, 98(1-2), 59-63. PMID: 12144042.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Activity-dependent "Resetting" of Baroreceptor Neurons in Culture: Role of Mechanosensitive vs. Voltage-gated Ion Channels. (Vols. 106). (19), pp. II-294. Circulation.

Chapleau, M. W., Sun, W. & Abboud, F. M. (2002). Altered Baro- and Chemoreflex Sensitivity in Young ApoE Knockout Mice before Development of Atherosclerotic Lesions. (Vols. 16). (5), pp. 828. FASEB.

Chapleau, M. W., Sun, W. & Abboud, F. M. (2002). Altered Baro- and Chemoreflex Sensitivity in Young ApoE Knockout Mice before Development of Atherosclerotic Lesions. Nebraska Physiological Society.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Differential Activity-dependent "Resetting" of Subtypes of Isolated Baroreceptor Neurons in Culture. (Vols. 12). (4), pp. 305. Clin Autonom Res.

Sun, W., Ma, X. Y., Abboud, F. M. & Chapleau, M. W. (2002). Differential Effects of Aging on Baro- and Chemoreflex Regulation of Arterial Pressure: Selective Impairment of Baroreflex in Senescent Mice. (Vols. 12). (4), pp. 323. Clin Autonom Res.

Hausberg, M., Morgan, D. A., Chapleau, M. W., Sivitz, W. I., Mark, A. L. & Haynes, W. G. (2002). Differential Modulation of Leptin-induced Sympathoexcitation by Baroreflex Activation. J Hypertens, 20, 1633-1641.

Ma, X. Y., Bielefeldt, K., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Direct Activation of Sympathetic Neurons by Angiotensin is Mediated by Both Protein Kinase C-dependent and PKC-independent Mechanisms. (Vols. 16). (4), pp. 498. FASEB.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Does Baroreceptor Resetting Occur in Isolated Baroreceptor Neurons in Culture. (Vols. 16). (5), pp. 832. FASEB.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Does Baroreceptor Resetting Occur in Isolated Baroreceptor Neurons in Culture. Nebraska Physiological Society.

Ma, X. Y., Sun, W., Snitsarev, V., Abboud, F. M. & Chapleau, M. W. (2002). Mechanisms of Baroreflex Impairment in Apo-E Knockout Mice with Atherosclerosis. (Vols. 29). pp. 92. Clin Exp Pharmacol Physiol.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2002). Nitric Oxide Functions as an Autocrine Negative-feedback Inhibitor of Membrane Excitability in Nodose Sensory Neurons. Society for Neuroscience.

Snitsarev, V., Yermolaieva, O., Whiteis, C. A., Abboud, F. M., Heinemann, S. H., Hosi, T. & Chapleau, M. W. (2002). Reactive Oxygen Species Generated during Action Potential Discharge Mediate "Activity-dependent Resetting" of Baroreceptor and Vagal Afferent Neurons in Culture. (Vols. 106). (19), pp. II-66. Circulation.

Vasquez, E. C., Meyrelles, S. S., Chapleau, M. W. & Johnson, A. K. (2001). Approaches for gene delivery to the subfornical organ and magnocellular neurons. Clinical and experimental pharmacology & physiology, 28(7), 602-9. PMID: 11458888.

Chapleau, M. W., Li, Z., Meyrelles, S. S., Ma, X. & Abboud, F. M. (2001). Mechanisms determining sensitivity of baroreceptor afferents in health and disease. Annals of the New York Academy of Sciences, 940, 1-19. PMID: 11458669.

Chapleau, M. W., Abboud, F. M. (2001). Neuro-cardiovascular regulation: from molecules to man. Introduction. Annals of the New York Academy of Sciences, 940, xiii-xxii. PMID: 11458711.

Ma, X., Chapleau, M. W., Whiteis, C. A., Abboud, F. M. & Bielefeldt, K. (2001). Angiotensin selectively activates a subpopulation of postganglionic sympathetic neurons in mice. Circulation research, 88(8), 787-93. PMID: 11325870.

Ma, X., Abboud, F. M. & Chapleau, M. W. (2001). A novel effect of angiotensin on renal sympathetic nerve activity in mice. Journal of hypertension, 19(3 Pt 2), 609-18. PMID: 11327637.

Fazan, R., Whiteis, C. A., Chapleau, M. W., Abboud, F. M. & Bielefeldt, K. (2001). Slow inactivation of sodium currents in the rat nodose neurons. Autonomic neuroscience : basic & clinical, 87(2-3), 209-16. PMID: 11476281.

Abboud, F. M., Chapleau, M. & Sun, W. (2001). Altered Baro- and Chemoreflex Sensitivity in Apo-E Knockout Mice Revealed by Carotid Artery Occlusion. IUPS.

Sun, W., Abboud, F. M. & Chapleau, M. W. (2001). Altered Baro- and Chemoreflex Sensitivity Revealed by Carotid Artery Occlusion Reflex in Apo-E Knockout Mice. (Vols. 15). (5), pp. 1146. FASEB.

Ma, X. Y., Chapleau, M., Whiteis, C. A., Snitsarev, V., Abboud, F. M. & Bielefeldt, K. (2001). Differential Effects of Angiotensin on Membrane Potential and Action Potential Discharge of Phasic and Tonic Sympathetic Neurons of Mice. (Vols. 104). (17), pp. II-320. Circulation.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2001). Distinction Between Activation of Mechanosensitive Channels and Membrane Excitability in Isolated Nodose Sensory Neurons. (Vols. 15). (5), pp. 1150. FASEB.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2001). Effect of Prostacyclin Analog on Mechanosensitive vs. Voltage-gated Ion Channels in Nodose Neurons. (Vols. 27). pp. 1812. Soc Neurosci Abstr.

Sun, W., Ma, X. Y., Abboud, F. M. & Chapleau, M. W. (2001). Impaired Baroreflex and Enhanced Chemoreflex Sensitivity in Normotensive Atherosclerotic Mice. (Vols. 11). (3), pp. 187. Clin Autonom Res.

Abboud, F. M., Chapleau, M., Snitsarev, V. & Whiteis, C. A. (2001). Independent Assessment of Mechanosensitivity and Membrane Excitability in Isolated Nodose Sensory Neurons: Effect of the DEG/ENaC Blocker Amiloride. IUPS.

Chapleau, M. W., Abboud, F. M. (Eds.) (2001). Neuro-Cardiovascular Regulation: From Molecules to Man. (Vols. 940). Annals of the New York Academy of Sciences.

Hausberg, M., Morgan, D. A., Chapleau, M. W., Mark, A. L. & Haynes, W. G. (2001). Regional Nonuniform Modulation of Leptin-induced Sympathoexcitation by Baroreflex Activation. Hypertension.

Snitsarev, V., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2001). Sensory Transduction of Vagal and Baroreceptor Afferents Revealed by Study of Isolated Nodose Neurons in Culture. Autonomic Neuroscience.

Abboud, F. M., Chapleau, M., Drummond, H. A., Ma, X. Y., Price, M. P. & Welsh, M. J. (2001). The DEG/ENaC Ion Channel Family Member BNC1 Contributes to Baroreceptor Mechanoelectrical Transduction in Vivo. IUPS.

Ma, X. Y., Price, M. P., Drummond, H. A., Welsh, M. J., Chapleau, M. W. & Abboud, F. M. (2001). The DEG/ENaC Ion Channel Family Member BNC1 Mediates Mechanical Transduction of Arterial Baroreceptor Nerve Activity in Vivo. (Vols. 15). (5), pp. 1146. FASEB.

Ma, X. Y., Abboud, F. M. & Chapleau, M. W. (2000). Altered Baroreflex Control of Renal Sympathetic Nerve Activity in Normotensive Apo-E Deficient Atherosclerotic Mice. (Vols. 43). (4), pp. 275. The Physiologist.

Whiteis, C. A., Fazan, R., Abboud, F. M. & Chapleau, M. W. (2000). Analysis of Baroreflex Sensitivity in Conscious Mice using Spectral Analysis. (Vols. 43). (4), pp. 275. The Physiologist.

Ma, X. Y., Chapleau, M., Whiteis, C. A., Abboud, F. M. & Bielefeldt, K. (2000). Angiotensin Selectively Activates a Subpopulation of Post-ganglionic Sympathetic Neurons in Mice. (Vols. 14). (4), pp. 625. FASEB.

Ma, X. Y., Fazan, R., Sun, W., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (2000). Approaches to Define Autonomic Reflex Abnormalities in Genetically Modified Mice. (Vols. 10). (4), pp. 231. Clin Autonom Res.

Ma, X. Y., Chapleau, M., Abboud, F. M. & Bielefeldt, K. (2000). Cellular Mechanism of Angiotensin-induced Activation of Postganglionic Sympathetic Neurons. (Vols. 26). (2), pp. 1953. Soc Neurosci Abstr.

Sun, W., Abboud, F. M. & Chapleau, M. W. (2000). Evaluation of Baroreflex and Chemoreflex by Carotid Artery Occlusion in Mice: A Method for Phenotypic Analysis of Deletion of Candidate Sensory Molecules. (Vols. 102). (18), pp. II-700. Circulation.

Meyrelles, S. S., Chapleau, M. (2000). Impaired Carotid Occlusion Reflex in apoE Deficient Mice and its Reversal by Gene Transfer to Carotid Sinus. (Vols. 18). (4), pp. 202. Hypertension.

Sun, W., Abboud, F. M. & Chapleau, M. W. (2000). Impaired Carotid Occlusion Reflex in ApoE Deficient Mice is Normalized with Age and Increasing Severity of Atherosclerotic Lesions. (Vols. 43). (4), pp. 276. The Physiologist.

Chapleau, M. W. (2000). Mechanisms Determining Sensitivity and Dysfunction of Baroreceptor Afferents in Health & Disease. (Vols. 43). (4), pp. 257. The Physiologist.

Chapleau, M. W., Drummond, H. A., Meyrelles, S. S., Li, Z., Welsh, M. J. & Abboud, F. M. (2000). Molecular Mechanisms Determining Baroreceptor Sensitivity and their Modulation by Gene Transfer. (Vols. 82). pp. 9. Autonomic Neuroscience.

Sun, W., Chapleau, M. (2000). Paradoxical Dual Effects of Lidocaine on Carotid Occlusion Reflex in Mice. (Vols. 14). (4), pp. 382. FASEB.

Sun, W., Chapleau, M. (2000). Paradoxical Dual Effects of Lidocaine on Carotid Occlusion Reflex in Mice. (Vols. 18). (4), pp. 233. Hypertension.

Meyrelles, S. S., Abboud, F. M. & Chapleau, M. W. (2000). Reversal of Impaired Carotid Occlusion Reflex by Gene Transfer in Young Apo-E Deficient Mice. (Vols. 43). (4), pp. 276. The Physiologist.

Ma, X. Y., Bielefeldt, K., Abboud, F. M. & Chapleau, M. W. (2000). Selective Direct Activation of Subtype of Sympathetic Neurons by Angiotensin in Mice. (Vols. 18). (4), pp. 75. Hypertension.

Bielefeldt, K., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (1999). Nitric oxide enhances slow inactivation of voltage-dependent sodium currents in rat nodose neurons. Neuroscience letters, 271(3), 159-62. PMID: 10507693.

Fazan, R., Ma, X. Y., Abboud, F. M. & Chapleau, M. W. (1999). An Electron Microscopy Study of the Renal Nerves in C57 Black Mice. (Vols. 13). (4), pp. 143. FASEB.

Meyrelles, S. S., Chapleau, M. (1999). Analysis of Carotid Baroreflex using Sequential Carotid Occlusion and Gene Transfer in Mice. (Vols. 33). (4), pp. 1085. Hypertension.

Ma, X. Y., Abboud, F. M. & Chapleau, M. W. (1999). Angiotensin-induced Activation of "Silent" Renal Sympathetic Nerves in Mice. (Vols. 13). (5), pp. 776. FASEB.

Chapleau, M. W. (1999). Arterial Baroreflexes.

Meyrelles, S. S., Chapleau, M. (1999). Carotid Baroreflex Control of Arterial Pressure Studied by Sequential Carotid Occlusion in Mice. (Vols. 13). (5), pp. 775. FASEB.

Fazan, R., Abboud, F. M., Chapleau, M. W. & Bielefeldt, K. (1999). Effects of Nitric Oxide on Inactivation Processes of Sodium Currents in Nodose Neurons. (Vols. 13). (5), pp. 777. FASEB.

Ma, X. Y., Sigmund, C. D., Abboud, F. M. & Chapleau, M. W. (1999). Impaired Central Mediation of the Baroreflex in Human Renin/Human Angiotensinogen Double Transgenic Hypertensive Mice. (Vols. 25). (2), pp. 1948. Soc Neurosci Abstr.

Fazan, R., Shaffer, R. A., Abboud, F. M. & Chapleau, M. W. (1999). Mechanisms of Heart Rate and Arterial Pressure Variability in Conscious Mice. (Vols. 33). (4), pp. 1076. Hypertension.

Ma, X. Y., Shaffer, R. A., Sigmund, C. D., Abboud, F. M. & Chapleau, M. W. (1999). Mechanisms of Impaired Baroreflex Control of Sympathetic Nerve Activity in Hypertensive Renin-Angiotensinogen Double Transgenic Mice. (Vols. 13). (5), pp. 775. FASEB.

Chapleau, M. W., Drummond, H. A., Welsh, M. J. & Abboud, F. M. (1999). Mechanisms of Sensory Transduction of Blood-Pressure-Sensing-Neurons in the Cardiovascular System. Japan Neuroscience Symposium.

Chapleau, M. W., Ma, X. Y. & Abboud, F. M. (1999). Novel Dual Effects of Angiotensin on the Pattern and Type of Sympathetic Outflow to Kidney in Mice. (Vols. 33). (4), pp. 1071. Hypertension.

Fazan, R., Shaffer, R. A., Abboud, F. M. & Chapleau, M. W. (1999). Parasympathetic and Sympathetic Contributions to Heart Rate and Arterial Pressure Variability in Conscious Mice. (Vols. 13). (4), pp. 453. FASEB.

Fazan, R., Ma, X. Y., Barreira, A. A., Abboud, F. M. & Chapleau, M. W. (1999). Qualitative and Quantitative Electron Microscopy Study of the Renal Nerves in C57 Black Mice. J Med Biol Res.

Kraske, S., Cunningham, J. T., Hajduczok, G., Chapleau, M. W., Abboud, F. M. & Wachtel, R. E. (1998). Mechanosensitive ion channels in putative aortic baroreceptor neurons. The American journal of physiology, 275(4 Pt 2), H1497-501. PMID: 9746502.

Li, Z., Chapleau, M. W., Bates, J. N., Bielefeldt, K., Lee, H. C. & Abboud, F. M. (1998). Nitric oxide as an autocrine regulator of sodium currents in baroreceptor neurons. Neuron, 20(5), 1039-49. PMID: 9620707.

Davis, G. J., Fazan, R., Abboud, F. M. & Chapleau, M. W. (1998). "Autocrine" Activity-dependent Inhibition of Baroreceptor Activity: A Novel Mechanism of Baroreceptor Resetting. (Vols. 24). (1), pp. 871. Soc Neurosci Abstr.

Meyrelles, S. S., Mao, H. Z., Sharma, R. V. & Chapleau, M. W. (1998). Baroreceptor Resetting and Vessel Remodeling after Gene Transfer of Nitric Oxide Synthase to Carotid Sinus. (Vols. 12). (5), pp. 687. FASEB.

Ma, X. Y., Abboud, F. M. & Chapleau, M. W. (1998). Baroreceptor Sensitivity and Baroreflex Control of Renal Sympathetic Nerve Activity in Mice. (Vols. 46). (3), pp. 200. J Invest Med.

Davis, G. J., Fazan, R., Abboud, F. M. & Chapleau, M. W. (1998). Brief Activation of Baroreceptor C-Fibers Causes Sustained Inhibition of Baroreceptor Activity: Possible Mechanism of Baroreceptor Resetting Following Acute Hypertension. (Vols. 46). (3), pp. 200. J Invest Med.

Ma, X. Y., Shaffer, R. A., Abboud, F. M. & Chapleau, M. W. (1998). Functional Genomics: Analysis of Afferent, Central and Efferent Components of Baroreceptor Reflex in Mice. (Vols. 12). (4), pp. 359. FASEB.

Meyrelles, S. S., Sharma, R. V. & Chapleau, M. W. (1998). Gene Transfer to Nodose Sensory Neurons in Culture and to Carotid Sinus in Vivo. American Society of Gene Therapy.

Fazan, R., Chapleau, M., Abboud, F. M. & Bielefeldt, K. (1998). Use-dependent Modulation of Sodium Channels in Nodose Sensory Neurons. (Vols. 24). (1), pp. 1076. Soc Neurosci Abstr.

Meyrelles, S. S., Sharma, R. V., Whiteis, C. A., Davidson, B. L. & Chapleau, M. W. (1997). Adenovirus-mediated gene transfer to cultured nodose sensory neurons. Brain research. Molecular brain research, 51(1-2), 33-41. PMID: 9427504.

Meyrelles, S. S., Mao, H. Z., Heistad, D. D. & Chapleau, M. W. (1997). Gene transfer to carotid sinus in vivo: a novel approach to investigation of baroreceptors. Hypertension, 30(3 Pt 2), 708-13. PMID: 9323010.

Sullivan, M. J., Sharma, R. V., Wachtel, R. E., Chapleau, M. W., Waite, L. J., Bhalla, R. C. & Abboud, F. M. (1997). Non-voltage-gated Ca2+ influx through mechanosensitive ion channels in aortic baroreceptor neurons. Circulation research, 80(6), 861-7. PMID: 9168789.

Li, Z., Lee, H. C., Bielefeldt, K., Chapleau, M. W. & Abboud, F. M. (1997). The prostacyclin analogue carbacyclin inhibits Ca(2+)-activated K+ current in aortic baroreceptor neurones of rats. The Journal of physiology, 501 ( Pt 2), 275-87. PMID: 9192300.

Li, Z., Chapleau, M., Bates, J. N., Lee, H., Whiteis, C. A. & Abboud, F. M. (1997). Differential Inhibitory Effects of Nitric Oxide and the Oxidizing Agent Dithiodipyridine on Sodium Currents of Baroreceptor Neurons. (Vols. 96). (8), pp. I-444. Circulation.

Su, X., Chapleau, M. & Gebhart, G. F. (1997). Effect of Antidepressants on Mechanosensitive Pelvic Nerve Afferent Fibers Innervating the Colon of the Rat. (Vols. 112). pp. 833. Gastroenterology.

Meyrelles, S. S., Mao, H. Z., Mora, M., Sharma, R. V., Ooboshi, H. & Chapleau, M. W. (1997). Gene Transfer into Baroreceptor Sensory Neurons and Carotid Sinus. (Vols. 29). (3), pp. 888. Hypertension.

Meyrelles, S. S., Mao, H. Z., Mora, M., Sharma, R. V., Ooboshi, H. & Chapleau, M. W. (1997). Gene Transfer into Baroreceptor Sensory Neurons and Carotid Sinus. (Vols. 45). (3), pp. 221. J Invest Med.

Chapleau, M. W., Meyrelles, S. S., Mao, H. Z., Sharma, R. V. & Heistad, D. D. (1997). Gene Transfer into Nodose Sensory Neurons in Culture and into Carotid Sinus In Vivo. Proc Int Union Physiol Sci.

Heistad, D., Faraci, F., Ooboshi, H. & Chapleau, M. W. (1997). Gene Transfer to Blood Vessels and Carotid Sinus. (Vols. 65). pp. 67. J Auton Nerv Syst.

Chapleau, M. W., Li, Z., Lee, H., Bates, J. N., Whiteis, C. A. & Abboud, F. M. (1997). Inhibition of Sodium Currents in Cultured Baroreceptor Neurons by Nitric Oxide. Proc Int Union Physiol Sci.

Meyrelles, S. S., Mao, H. Z., Sharma, R. V., Heistad, D. D. & Chapleau, M. W. (1997). Modulation of Baroreceptor Sensitivity by Gene Transfer of Nitric Oxide Synthase to Carotid Sinus Adventitia. (Vols. 30). (3), pp. 471. Hypertension.

Abboud, F. M., Chapleau, M. W. (1997). Modulation of Mechanotransduction in Aortic Baroreceptor Neurons. Fundam Clin Pharmacol, 11(1), 58s-63s.

Li, Z., Lee, H., Bates, J. N., Whiteis, C. A., Chapleau, M. W. & Abboud, F. M. (1997). Nitric Oxide Inhibits Sodium Current of Rat Aortic Baroreceptor Neurons. (Vols. 45). (3), pp. 221. J Invest Med.

Li, Z., Lee, H., Bates, J. N., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (1997). Nitric Oxide Inhibits Sodium Currents of Baroreceptor Neurons by Nitrosylation Independent of Cyclic GMP. (Vols. 96). (8), pp. I-444. Circulation.

Li, Z., Bates, J. N., Lee, H., Abboud, F. M. & Chapleau, M. W. (1997). Oxidation Selectively Inhibits Tetrodotoxin-Sensitive Sodium Current in Isolated Baroreceptor Neurons. (Vols. 23). (2), pp. 1519. Soc Neurosci Abstr.

Meyrelles, S. S., Sharma, R. V., Davidson, B. L. & Chapleau, M. W. (1997). Selective Induction of Endogenous ?-Gal Gene Expression in Nodose Sensory Neurons In Vivo. (Vols. 11). (3), pp. 17. FASEB.

Nuyt, A. M., Segar, J. L., Holley, A. T., O'Mara, M. S., Chapleau, M. W. & Robillard, J. E. (1996). Arginine vasopressin modulation of arterial baroreflex responses in fetal and newborn sheep. The American journal of physiology, 271(6 Pt 2), R1643-53. PMID: 8997365.

Li, Z., Mao, H. Z., Abboud, F. M. & Chapleau, M. W. (1996). Oxygen-derived free radicals contribute to baroreceptor dysfunction in atherosclerotic rabbits. Circulation research, 79(4), 802-11. PMID: 8831504.

Mao, H. Z., Li, Z. & Chapleau, M. W. (1996). Platelet activation in carotid sinuses triggers reflex sympathoinhibition and hypotension. Hypertension, 27(3 Pt 2), 584-90. PMID: 8613208.

Meyrelles, S. S., Sharma, R. V., Whiteis, C. A., Davidson, B. L. & Chapleau, M. W. (1996). Adenoviral-mediated Gene Transfer into Baroreceptor Neurons. (Vols. 10). (3), pp. 62. FASEB.

Nuyt, A. M., Merrill, D. C., Segar, J. L., Chapleau, M. W. & Robillard, J. E. (1996). Autonomic Adjustments to Severe Hypotension During Fetal and Postnatal Life: Ontogeny of the Bezold-Jarisch Reflex. (Vols. 39). (4), pp. 33. Pediatric Res.

Nuyt, A. M., Holley, A. T., Chapleau, M. W. & Robillard, J. E. (1996). Effect of Nitric Oxide (NO) on Arterial Baroreflex Baroreceptor Activity During Development. (Vols. 39). (4), pp. 77. Pediatric Res.

Li, Z., Lee, H., Bielefeldt, K., Abboud, F. M. & Chapleau, M. W. (1996). K+ Channels Mediate Prostacyclin-induced Increase in Excitability of Mechanosensitive Baroreceptor Neurons. Neuropharmacology.

Li, Z., Lee, H., Bielefeldt, K., Abboud, F. M. & Chapleau, M. W. (1996). K+ Current Inhibition by Prostacyclin Analog Carbacyclin in Baroreceptor Neurons Requires G-Protein Activation and cAMP Formation. (Vols. 10). (3), pp. 16. FASEB.

Li, Z., Lee, H., Bates, J. N., Whiteis, C. A., Abboud, F. M. & Chapleau, M. W. (1996). Nitric Oxide (NO) Inhibits Sodium Current of Rat Aortic Baroreceptor Neurons. (Vols. 94). (8), pp. I-491. Circulation.

Li, Z., Chapleau, M., Lee, H., Bates, J. N. & Abboud, F. M. (1996). Nitric Oxide Inhibits Na+ Current of Isolated Baroreceptor Neurons in Culture. (Vols. 44). (3), pp. 247. J Invest Med.

Nuyt, A. M., Holley, A. T., Chemtob, S., Chapleau, M. W., Segar, J. L. & Robillard, J. E. (1996). Role of Endogenous Prostaglandins in the Regulation of Arterial Baroreceptor Activity During Development. (Vols. 39). (4), pp. 234. Pediatric Res.

Li, Z., Su, X. & Chapleau, M. W. (1995). Role of cyclooxygenase metabolites in mediating platelet-induced baroreceptor dysfunction. The American journal of physiology, 269(2 Pt 2), H599-608. PMID: 7653624.

Chapleau, M. W., Cunningham, J. T., Sullivan, M. J., Wachtel, R. E. & Abboud, F. M. (1995). Structural versus functional modulation of the arterial baroreflex. Hypertension, 26(2), 341-7. PMID: 7543454.

Sharma, R. V., Chapleau, M. W., Hajduczok, G., Wachtel, R. E., Waite, L. J., Bhalla, R. C. & Abboud, F. M. (1995). Mechanical stimulation increases intracellular calcium concentration in nodose sensory neurons. Neuroscience, 66(2), 433-41. PMID: 7477884.

Matsuda, T., Bates, J. N., Lewis, S. J., Abboud, F. M. & Chapleau, M. W. (1995). Modulation of baroreceptor activity by nitric oxide and S-nitrosocysteine. Circulation research, 76(3), 426-33. PMID: 7859388.

Su, X., Li, Z. & Chapleau, M. W. (1995). Activated Platelets Alter Activity of Baroreceptor Fiber Types in a Selective and Differential Manner. AHA.

Chapleau, M. W., Hajduczok, G., Sharma, R. V., Wachtel, R. E., Cunningham, J. T., Sullivan, M. J. & Abboud, F. M. (1995). Mechanisms of baroreceptor activation. Clinical and experimental hypertension (New York, N.Y. : 1993), 17(1-2), 1-13. PMID: 7735260.

Chapleau, M. W., Sullivan, M. J., Cunningham, J. T., Wachtel, R. E. & Abboud, F. M. (1995). Mechanoelectrical Transduction in Baroreceptor Neurons - Evidence of Stretch-Activated Ion Channels. (Vols. 16). pp. 458. Eur Heart J.

Nuyt, A. M., Mao, H. Z., Abboud, F. M. & Chapleau, M. W. (1995). Nitric Oxide Modulates Arterial Baroreceptor Activity via Ca-Activated K Channels In Vivo. (Vols. 37). (4), pp. 31. Pediatric Res.

Li, Z., Chapleau, M. W. (1995). Platelet-induced suppression of baroreceptor activity is mediated by a stable diffusible factor. Journal of the autonomic nervous system, 51(1), 59-65. PMID: 7722216.

Chapleau, M. W., Su, X. & Li, Z. (1995). Platelets Aggregating in Carotid Sinus Selectively Modulate Activity of Baroreceptor Fiber Types. (Vols. 9). (3), pp. 7. FASEB.

Mao, H. Z., Chapleau, M. (1995). Platelets Aggregating in Carotid Sinuses Trigger Reflex Inhibition of Sympathetic Nerve Activity and Hypotension. (Vols. 26). (3), pp. 559. Hypertension.

Li, Z., Lee, H., Bielefeldt, K., Chapleau, M. W. & Abboud, F. M. (1995). Prostacyclin Analog Carbacyclin Inhibits Ca2+- Activated K+ Current in Cultured Baroreceptor Neurons. (Vols. 21). (3), pp. 1831. Soc Neurosci Abstr.

Li, Z., Lee, H., Bielefeldt, K., Abboud, F. M. & Chapleau, M. W. (1995). The Prostacyclin Analog Carbacyclin Enhances Membrane Excitability of Isolated Baroreceptor Neurons in Culture. (Vols. 92). (8), pp. I-134. Circulation.

Li, Z., Lee, H., Bielefeldt, K., Chapleau, M. W. & Abboud, F. M. (1995). The Prostacyclin Analog Carbacyclin Increases the Excitability of Isolated Baroreceptor Neurons and Inhibits Outward K+ Current. (Vols. 43). (3), pp. 451. J Invest Med.

Hajduczok, G., Chapleau, M. W., Ferlic, R. J., Mao, H. Z. & Abboud, F. M. (1994). Gadolinium inhibits mechanoelectrical transduction in rabbit carotid baroreceptors. Implication of stretch-activated channels. The Journal of clinical investigation, 94(6), 2392-6. PMID: 7527431.

Chapleau, M. W., Abboud, F. M. (1994). Modulation of baroreceptor activity by ionic and paracrine mechanisms: an overview. Brazilian journal of medical and biological research = Revista brasileira de pesquisas mÃ©dicas e biolÃ³gicas / Sociedade Brasileira de BiofÃsica ... [et al.], 27(4), 1001-15. PMID: 7522078.

Sullivan, M. J., Sharma, R. V., Chapleau, M. W., Wachtel, R. E., Fankhauser, L., Bhalla, R. C. & Abboud, F. M. (1994). Baroreceptor Neurons Respond to Mechanical Stimulation with Increases in Intracellular Calcium. (Vols. 8). (4), pp. 334. FASEB.

McDowell, T. S., Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1994). Baroreflex dysfunction in diabetes mellitus. I. Selective impairment of parasympathetic control of heart rate. The American journal of physiology, 266(1 Pt 2), H235-43. PMID: 8304504.

McDowell, T. S., Hajduczok, G., Abboud, F. M. & Chapleau, M. W. (1994). Baroreflex dysfunction in diabetes mellitus. II. Site of baroreflex impairment in diabetic rabbits. The American journal of physiology, 266(1 Pt 2), H244-9. PMID: 8304505.

Chapleau, M. W., Sullivan, M. J., Cunningham, J. T., Wachtel, R. E., Mao, H. Z. & Abboud, F. M. (1994). Evidence that Gadolinium-Sensitive Stretch-Activated Ion Channels Are the Arterial Baroreceptor Mechano-transducers. FASEB.

Sullivan, M. J., Sharma, R. V., Wachtel, R. E., Chapleau, M. W., Fankhauser, L., Bhalla, R. C. & Abboud, F. M. (1994). Mechanism of Mechano-electrical Transduction in Putative Baroreceptor Neurons. (Vols. 42). (2), pp. 257. Clin Res.

Chapleau, M. W., Matsuda, T., Mao, H. Z., Su, X. & Abboud, F. M. (1994). Modulation of Baroreceptor Activity by NO: Implications for Blood Pressure Regulation. Therapeutic Application and Commercial Development.

Su, X., Chapleau, M. (1994). Nitric Oxide Released from Carotid Sinus Sensory Nerves Inhibits Activity of Baroreceptor A-Fibers. (Vols. 37). (4), pp. A-8. The Physiologist.

Mao, H. Z., Su, X. & Chapleau, M. W. (1994). The Antidepressant Phenelzine Causes Centrally-Mediated Inhibition of Sympathetic Nerve Activity: A Possible Cause of Orthostatic Hypotension. (Vols. 90). (4), pp. I-474. Circulation.

Mao, H. Z., Li, Z. & Chapleau, M. W. (1994). The Antidepressant Phenelzine Suppresses Baroreceptor Activity through a Nitric Oxide Dependent Mechanism. (Vols. 8). (4), pp. 334. FASEB.

Cunningham, J. T., Kraske, S., Fankhauser, L., Wachtel, R. E., Chapleau, M. W. & Abboud, F. M. (1994). Whole Cell Currents Induced by Hypoosmotic Stretch in Nodose Ganglion Neurons. (Vols. 8). (4), pp. 332. FASEB.

Segar, J. L., Merrill, D. C., Chapleau, M. W. & Robillard, J. E. (1993). Hemodynamic changes during endotracheal suctioning are mediated by increased autonomic activity. Pediatric research, 33(6), 649-52. PMID: 8378127.

Chapleau, M. W., Lu, J., Hajduczok, G. & Abboud, F. M. (1993). Mechanism of baroreceptor adaptation in dogs: attenuation of adaptation by the K+ channel blocker 4-aminopyridine. The Journal of physiology, 462, 291-306. PMID: 8331585.

Mao, H. Z., Li, Z. & Chapleau, M. W. (1993). Antidepressant Agents Impair Baroreceptor Sensitivity: A Possible Mechanism of Orthostatic Hypotension. (Vols. 41). (3), pp. 628. Clin Res.

Sharma, R. V., Wachtel, R. E., Hajduczok, G., Chapleau, M. W., Fankhauser, L., Bhalla, R. C. & Abboud, F. M. (1993). Calcium Influx Mediates Mechano-sensitive Intracellular Calcium Transients in Nodose Sensory Neurons. (Vols. 7). (3), pp. 94. FASEB.

Ma, S., Felder, R. B., Chapleau, M. W. & Abboud, F. M. (1993). Effects of Nitroglycerin on Neuronal Activity in the Solitary Tract Nucleus In Vivo and In Vitro. (Vols. 7). (3), pp. 99. FASEB.

Li, Z., Chapleau, M. (1993). Mechanisms Involved in Platelet-Induced Baroreceptor Dysfunction. Proc Int Union Physiol Sci.

Chapleau, M. W., Abboud, F. M. (1993). Mechanisms of Adaptation and Resetting of the Baroreceptor Reflex.

Abboud, F. M., Chapleau, M. (1993). Mechanisms of Adaptation and Resetting of the Baroreceptor Reflex. Proc Int Union Physiol Sci.

Li, Z., Abboud, F. M. & Chapleau, M. W. (1993). Oxygen-Derived Free Radicals Contribute to Baroreceptor Dysfunction in Atherosclerosis. (Vols. 7). (3), pp. 94. FASEB.

Chapleau, M. W., Li, Z. & Abboud, F. M. (1993). Oxygen-Derived Free Radicals Suppress Baroreceptor Activity: A Mechanism of Baroreceptor Dysfunction in Atherosclerosis. Proc Int Union Physiol Sci.

Mao, H. Z., Li, Z. & Chapleau, M. W. (1993). The Antidepressant Tranylcypromine Causes Profound Impairment of Baroreceptor Sensitivity. (Vols. 88). (4), pp. I-362. Circulation.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1992). Suppression of baroreceptor discharge by endothelin at high carotid sinus pressure. The American journal of physiology, 263(1 Pt 2), R103-8. PMID: 1636777.

Li, Z., Abboud, F. M. & Chapleau, M. W. (1992). Aggregating human platelets in carotid sinus of rabbits decrease sensitivity of baroreceptors. Circulation research, 70(4), 644-50. PMID: 1551191.

Chapleau, M. W. (1992). Are arterial pressure and deformation the sole determinants of baroreceptor activity? Importance of humoral and endothelial modulation in normal and disease states. Hypertension, 19(3), 278-80. PMID: 1548052.

Chapleau, M. W., Abboud, F. M. (1992). Does prostacyclin sensitize arterial baroreceptors?. The American journal of physiology, 262(2 Pt 2), H621-2. PMID: 1610443.

Lu, J. J., Abboud, F. M. & Chapleau, M. W. (1992). Absence of Acute Resetting in a Subpopulation of Baroreceptors (BR) During Hypertension. (Vols. 6). (4), pp. 1524. FASEB.

Li, Z., Chapleau, M. (1992). Activated Platelets Release a Stable Diffusible Mediator that Suppresses Baroreceptor Activity. (Vols. 40). (3), pp. 727. Clin Res.

Chapleau, M. W. (1992). Cardiovascular Mechanoreceptors.

Ma, S., Chapleau, M. & Abboud, F. M. (1992). Defect in Central Mediation of the Baroreflex with Aging. (Vols. 6). (4), pp. 951. FASEB.

Matsuda, T., Chapleau, M., Bates, J. N., Lewis, S. J. & Abboud, F. M. (1992). Endogenous Nitric Oxide Suppresses Barorecep¬tor Activity by a cGMP Independent Mechanism. (Vols. 86). (4), pp. I-482. Circulation.

Chapleau, M. W., Li, Z. (1992). Endogenous Prostanoids Oppose Platelet-Induced Suppression of Baroreceptor Activity. (Vols. 86). (4), pp. I-15. Circulation.

Matsuda, T., Chapleau, M., Lewis, S. J., Bates, J. N. & Abboud, F. M. (1992). Endothelial Factors S-Nitrosocysteine (CysNO) and Nitric Oxide (NO) Suppress Baroreceptor Activity. (Vols. 6). (4), pp. 952. FASEB.

Matsuda, T., Chapleau, M., Bates, J. N., Lewis, S. J. & Abboud, F. M. (1992). Modulation of Baroreceptor Activity by Nitric Oxide. (Vols. 40). (3), pp. 702. Clin Res.

Li, Z., Abboud, F. M. & Chapleau, M. W. (1992). Oxygen Derived Free Radicals Suppress Carotid Sinus Nerve Activity: Possible Mechanism of Baroreceptor Dysfunction in Atherosclerosis. (Vols. 86). (4), pp. I-483. Circulation.

Ma, S., Chapleau, M. & Abboud, F. M. (1992). Paradoxical Bradycardia and Sympathoinhibition by Nitroglycerin Occurs in Old but Not Young Rats and is Related to Impaired Baroreflexes. (Vols. 40). (2), pp. 155. Clin Res.

Hajduczok, G., Chapleau, M. W., Johnson, S. L. & Abboud, F. M. (1991). Increase in sympathetic activity with age. I. Role of impairment of arterial baroreflexes. The American journal of physiology, 260(4 Pt 2), H1113-20. PMID: 1901459.

Hajduczok, G., Chapleau, M. W. & Abboud, F. M. (1991). Increase in sympathetic activity with age. II. Role of impairment of cardiopulmonary baroreflexes. The American journal of physiology, 260(4 Pt 2), H1121-7. PMID: 2012218.

Chapleau, M. W. (1991). Types of baroreceptor afferent neurons. Circulation research, 68(2), 619-20. PMID: 1991360.

Li, Z., Chapleau, M. (1991). Activated Platelets Release a Stable Diffusible Mediator that Suppresses Baroreceptor Activity. AHA.

Li, Z., Chapleau, M. (1991). Aggregated Platelets Release a Factor that Suppresses Baroreceptor Activity. (Vols. 5). (5), pp. 1033. FASEB.

Li, Z., Abboud, F. M. & Chapleau, M. W. (1991). Neural Discharge from Arterial Baroreceptors is Suppressed by Aggregating Platelets and Damaged Endothelium - Possible Mechanism of Neurogenic Hypertension in Atherosclerosis. (Vols. 39). (2), pp. 296. Clin Res.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1991). Paracrine Modulation of Baroreceptor Activity by Vascular Endothelium. News Physiol Sci, 6, 210-214.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1991). Paracrine role of prostanoids in activation of arterial baroreceptors: an overview. Clinical and experimental hypertension. Part A, Theory and practice, 13(5), 817-24. PMID: 1773513.

Li, Z., Chapleau, M. (1991). Platelet Products Modulate Sensitivity of Arterial Baroreceptors: Role of Thromboxane, Serotonin, and ADP. (Vols. 84). (4), pp. II-99. Circulation.

Hajduczok, G., Chapleau, M. W. & Abboud, F. M. (1991). Rapid adaptation of central pathways explains the suppressed baroreflex with aging. Neurobiology of aging, 12(5), 601-4. PMID: 1770991.

Xie, P. L., McDowell, T. S., Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1991). Rapid baroreceptor resetting in chronic hypertension. Implications for normalization of arterial pressure. Hypertension, 17(1), 72-9. PMID: 1986984.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1991). Resetting of the Arterial Baroreflex: Peripheral and Central Mechanisms.

Chen, H. I., Chapleau, M. W., McDowell, T. S. & Abboud, F. M. (1990). Prostaglandins contribute to activation of baroreceptors in rabbits. Possible paracrine influence of endothelium. Circulation research, 67(6), 1394-404. PMID: 2245501.

Xie, P. L., Chapleau, M. W., McDowell, T. S., Hajduczok, G. & Abboud, F. M. (1990). Mechanism of decreased baroreceptor activity in chronic hypertensive rabbits. Role of endogenous prostanoids. The Journal of clinical investigation, 86(2), 625-30. PMID: 2117025.

Chapleau, M. W., Johnson, S. L., Hajduczok, G. & Abboud, F. M. (1990). Carotid Sinus Nerve Activity is Flow-Dependent During Static and Pulsatile Pressure. (Vols. 8). (3), pp. 64. Hypertension.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1990). Central Adaptation of the Baroreflex During Sustained Elevations in Arterial Pressure. International Symposium on SHR.

Xie, P., McDowell, T. S., Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1990). Decreased Prostacyclin Production Contributes to Baroreceptor Impairment in Hypertensive Rabbits. International Symposium on SHR.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1990). Dual Effects of Endothelin on Baroreceptor Activity. (Vols. 82). (4), pp. II-11. Circulation.

Hajduczok, G., Chapleau, M. & Abboud, F. M. (1990). Increased Renal Sympathetic Activity with Aging: Role of Arterial and Cardiopulmonary Reflexes. (Vols. 8). (3), pp. 54. Hypertension.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1990). Mechanism of Adaptation of Baroreceptors in Acute Hypertension: Role of A-Current. (Vols. 16). (3), pp. 348. Hypertension.

Hajduczok, G., Ferlic, R. J., Chapleau, M. W. & Abboud, F. M. (1990). Mechanism of Mechano-transduction of Arterial Baroreceptors. (Vols. 4). (3), pp. 285. FASEB.

Hajduczok, G., Chapleau, M. & Abboud, F. M. (1990). Rapid Adaptation Rather than Impaired Neurons Explain the Suppressed Baroreflex with Aging. Winner: Henry Christian Memorial Award. (Vols. 38). (2), pp. 412. Clin Res.

McDowell, T. S., Chapleau, M., Hajduczok, G. & Abboud, F. M. (1990). Selective Impairment of Parasympathetic Control of Heart Rate in Conscious Diabetic Rabbits. (Vols. 4). (3), pp. 285. FASEB.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1990). Selective Modulation of Dynamic vs. Sustained Baroreceptor Responses by Na+ Pump and A-Current. (Vols. 82). (4), pp. II-9. Circulation.

McDowell, T. S., Chapleau, M., Hajduczok, G. & Abboud, F. M. (1990). Site of Baroreflex Dysfunction in Diabetes. (Vols. 82). (4), pp. III-335. Circulation.

Chapleau, M. W., Abboud, F. M. (1989). Determinants of sensitization of carotid baroreceptors by pulsatile pressure in dogs. Circulation research, 65(3), 566-77. PMID: 2766484.

McDowell, T. S., Axtelle, T. S., Chapleau, M. W. & Abboud, F. M. (1989). Prostaglandins in carotid sinus enhance baroreflex in rabbits. The American journal of physiology, 257(2 Pt 2), R445-50. PMID: 2504063.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Pulsatile activation of baroreceptors causes central facilitation of baroreflex. The American journal of physiology, 256(6 Pt 2), H1735-41. PMID: 2735443.

Chapleau, M. W., Johnson, S. L., Hajduczok, G. & Abboud, F. M. (1989). "Rheoreceptors" in the Carotid Sinus are Activated by Flow at Constant Pressure: Interactions Between Flow and Pulsatility. (Vols. 37). (4), pp. 874. Clin Res.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Adaptation of Baroreceptors with Elevated Static Arterial Pressure is Absent or Attenuated with Pulsatile Pressure. (Vols. 15). pp. 336. Soc Neurosci Abstr.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Contrasting Effects of Static and Pulsatile Pressure on Reset¬ting of Baroreceptors and on Central Adaptation of the Baroreflex. IUPS.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Endothelin Suppresses Baroreceptor Activity: A New Mechanism Contributing to Hypertension. (Vols. 14). (3), pp. 336-337. Hypertension.

Hajduczok, G., Chapleau, M., Johnson, S. L. & Abboud, F. M. (1989). Exercise Training Does Not Restore the Impaired Baroreflex with Age. (Vols. 80). (4), pp. II289. Circulation.

Hajduczok, G., Chapleau, M. & Abboud, F. M. (1989). Loss of Cardiopulmonary (CP) Inhibition of Baroreflex Function with Age. (Vols. 3). (3), pp. 857. FASEB.

Hajduczok, G., Chapleau, M. W. & Abboud, F. M. (1989). Mechanisms of Activation of Arterial Baroreceptors and the Central Integration of Baroreceptor Activity.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Pattern of Baroreceptor Discharge Determines the Magnitude of Inhibition of Sympathetic Nerve Activity. (Vols. 17). pp. 158. Proc Int Union Physiol Sci.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Peripheral and central mechanisms of baroreflex resetting. Clinical and experimental pharmacology & physiology. Supplement, 15, 31-43. PMID: 2680188.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1989). Pulsatile Pressure Attenuates both Baroreceptor and CNS Components of Baroreflex Resetting. (Presented at IUPS Satellite Symposium. (Vols. 136). (584), pp. 8. Acta Physiol Scand.

Chapleau, M. W., McDowell, T. S., Hajduczok, G. & Abboud, F. M. (1989). Sensitization of Baroreceptors Following Pulsatile Pressure is Not Caused by Prostacyclin or Other Endothelial Factors. (Vols. 3). (3), pp. 857. FASEB.

Hajduczok, G., Chapleau, M. W. & Abboud, F. M. (1988). Rheoreceptors in the carotid sinus of dog. Proceedings of the National Academy of Sciences of the United States of America, 85(19), 7399-403. PMID: 3174642.

Abboud, F. M., Chapleau, M. W. (1988). Effects of pulse frequency on single-unit baroreceptor activity during sine-wave and natural pulses in dogs. The Journal of physiology, 401, 295-308. PMID: 3171989.

Chapleau, M. W., Hajduczok, G., Shasby, D. M. & Abboud, F. M. (1988). Activated endothelial cells in culture suppress baroreceptors in the carotid sinus of dog. Hypertension, 11(6 Pt 2), 586-90. PMID: 3134304.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1988). Mechanisms of resetting of arterial baroreceptors: an overview. The American journal of the medical sciences, 295(4), 327-34. PMID: 2834951.

Chapleau, M. W., Wilson, L. B., Gregory, T. J. & Levitzky, M. G. (1988). Chemoreceptor stimulation interferes with regional hypoxic pulmonary vasoconstriction. Respiration physiology, 71(2), 185-200. PMID: 3340818.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1988). Adaptation of "Central Neurons" Causes Escape of Sympathetic Activity from Baroreflex Inhibition. (Vols. 78). (4), pp. II-543. Circulation.

Xie, P., Chapleau, M., McDowell, T. S., Hajduczok, G. & Abboud, F. M. (1988). Chronic Resetting of Baroreceptors Differs in Hypercholesterolemic vs. Renal Hypertensive Rabbits. (Vols. 31). (4), pp. 198. The Physiologist.

Xie, P., McDowell, T. S., Hajduczok, G., Chapleau, M. W. & Abboud, F. M. (1988). Contribution of Cyclooxygenase Metabolites to Baroreceptor Activation in Hypercholesterolemic (HC) Rab¬bits. (Vols. 78). (4), pp. II-177. Circulation.

Xie, P., Chapleau, M., McDowell, T. S. & Abboud, F. M. (1988). Cyclooxygenase Metabolites Contribute to Baroreceptor Activation in Normotensive but Not Hypertensive Rabbits. (Vols. 2). (6), pp. 1716. FASEB.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1988). Escape of Sympathetic Activity from Baroreflex Inhibition: Critical Role of Adaptation of Central Neurons. (Vols. 36). (6), pp. 862. Clin Res.

Xie, P., Chapleau, M., McDowell, T. S. & Abboud, F. M. (1988). Mechanism of Fluctuation of Arterial Pressure in Hypertension - Impaired Resetting of Baroreceptors. (Vols. 36). (3), pp. 547. Clin Res.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1988). New insights into the influence of pulsatile pressure on the arterial baroreceptor reflex. Clinical and experimental hypertension. Part A, Theory and practice, 10 Suppl 1, 179-91. PMID: 3072123.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1988). Phasic Baroreceptor Activity Causes Greater Reflex Sympathetic Inhibition Regardless of Changes in Afferent Activity per Unit Time. (Vols. 2). (4), pp. 718. FASEB.

McDowell, T. S., Xie, P., Chapleau, M. W. & Abboud, F. M. (1988). Rapid Reversal of Chronic Resetting in Renal Hypertensive Rabbits by Acute Hypotension. (Vols. 2). (5), pp. 1279. FASEB.

Chapleau, M. W., Johnson, S. L., Hajduczok, G. & Abboud, F. M. (1988). Relative Contribution of Pulse Amplitude and Frequency to Post-Pulsatile Pressure Sensitization of Barore¬ceptors. (Vols. 31). (4), pp. 198. The Physiologist.

Abboud, F. M., Chapleau, M. & Hajduczok, G. (1988). Types and Mechanisms of Baroreceptor Resetting. International Society of Hypertension.

Chapleau, M. W., Abboud, F. M. (1987). Contrasting effects of static and pulsatile pressure on carotid baroreceptor activity in dogs. Circulation research, 61(5), 648-58. PMID: 3664974.

Chapleau, M. W., Heesch, C. M. & Abboud, F. M. (1987). Prevention or attenuation of baroreceptor resetting by pulsatility during elevated pressure. Hypertension, 9(6 Pt 2), III137-41. PMID: 3596780.

Hajduczok, G., Chapleau, M. & Abboud, F. M. (1987). Are the Arterial Baroreceptors Sensitive to Change in Flow at a Constant Pressure. (Vols. 35). (3), pp. 284. Clin Res.

Hajduczok, G., Chapleau, M. & Abboud, F. M. (1987). Differential Effects of Flow on Carotid Sinus Baroreceptor Nerve Activity at Constant Pressures. (Vols. 46). (3), pp. 320. Fed Proc.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1987). Endothelial Factors May Alter Baroreceptor Activity. (Vols. 10). (4), pp. 355. Hypertension.

Chapleau, M. W., Hajduczok, G., Brotherton, A. & Abboud, F. M. (1987). Role of Endothelium in Baroreceptor Activation - Acute Effect of Endothelial Denudation. (Vols. 46). (3), pp. 320. Fed Proc.

Chen, H. I., Chapleau, M. & Abboud, F. M. (1987). Role of Prostaglandins in "Acute Resetting" of Arterial Baroreceptors. (Vols. 46). (4), pp. 1250. Fed Proc.

Chapleau, M. W., Hajduczok, G. & Abboud, F. M. (1987). The Pattern of Baroreceptor Afferent Impulses is More Important than the Number of Impulses per Unit Time in Reflex Inhibi¬tion of Sympathetic Activity. (Vols. 35). (6), pp. 875. Clin Res.

Chen, H. I., McDowell, T. S., Chapleau, M. W. & Abboud, F. M. (1987). The Role of Endothelium in Baroreceptor Activation: Endothelial Denudation Suppresses Baroreceptor Activity. (Vols. 76). (4), pp. 348. Circulation.

Abboud, F. M., Chapleau, M. (1986). "Diastolic Silence" of Carotid Baroreceptors at Pulsatile Pressures Above Threshold - Role of Ionic Mechanisms. (Vols. 45). (3), pp. 296. Fed Proc.

McDowell, T. S., Chapleau, M. & Abboud, F. M. (1986). Arachidonic Acid Enhances Baroreflex Inhibition of Sympathetic Nerve Activity and Heart Rate. (Vols. 34). (2), pp. 482. Clin Res.

Chapleau, M. W., Abboud, F. M. (1986). Effect of a Change from Static to Pulsatile Pressure on Single and Multiunit Baroreceptor Activity - Unit Recruitment vs. Diastolic Silence. (Vols. 45). (3), pp. 155. Fed Proc.

Axtelle, T. S., Chapleau, M., McDowell, T. S. & Abboud, F. M. (1986). Indomethacin Inhibits Carotid Baroreceptors - Possible Role of Endothelium in Activation of Arterial Baroreceptors. (Vols. 34). (4), pp. 918. Clin Res.

Chapleau, M. W., Abboud, F. M. (1986). Mechanisms of Carotid Baroreceptor Stimulation with Static and Dynamic Stretch. (Vols. 16). pp. 43. Proc Int Union Physiol Sci.

Chapleau, M. W., Heesch, C. M. & Abboud, F. M. (1986). Pulsatility may Sensitize Arterial Baroreceptors and Prevent the Phenomenon of "Acute Resetting.". (Vols. 24). (4), pp. 959. Clin Res.

Chapleau, M. W., Abboud, F. M. (1986). Sensitization of Arterial Baroreceptors by Pulsatile Pressure. (Vols. 8). (9), pp. 831. Hypertension.

Chapleau, M. W., Abboud, F. M. (1986). Sensitization of Baroreceptors Following Pulsatile Pressure is Related to Pulsatile Strain. (Vols. 29). (4), pp. 108. The Physiologist.

Axtelle, T. S., Chapleau, M., McDowell, T. S. & Abboud, F. M. (1986). The Role of Endothelium in Activation of the Arterial Baroreflex. (Vols. 29). (4), pp. 108. The Physiologist.

Hall, S. M., Chapleau, M., Cairo, J. & Levitzky, M. G. (1985). Effect of high-frequency positive-pressure ventilation on halothane ablation of hypoxic pulmonary vasoconstriction. Critical care medicine, 13(8), 641-5. PMID: 3893888.

Chapleau, M. W., Fish, R. E. & Levitzky, M. G. (1985). Regional hypoxic pulmonary vasoconstriction in dogs with asymptomatic dirofilariasis. American journal of veterinary research, 46(6), 1341-5. PMID: 4026011.

Gregory, T. J., Weinberg, A. B., Chapleau, M. W., Summer, W. R. & Levitzky, M. G. (1985). Age Decreases Non-Starling Resistance in Ferret Lungs. (Vols. 44). (5), pp. 1755. Fed Proc.

Chapleau, M. W. (1985). Hypoxic Pulmonary Vasoconstriction in Dogs: Modification by Arterial Chemoreceptor Stimulation and Heartworm Disease.

Chapleau, M. W., Fankhauser, L. J. & Abboud, F. M. (1985). Influence of Pulse Frequency on Single Unit Baroreceptor Discharge. (Vols. 28). (4), pp. 273. The Physiologist.

Gregory, T. J., Weinberg, A. B., Chapleau, M. W., Summer, W. R. & Levitzky, M. G. (1985). Sex vs. Age as the Cause of Attenuation of Hypoxic Pulmonary Vasoconstriction in Ferrets. (Vols. 131). pp. 415. Am Rev Resp Dis.

Chapleau, M. W., Wilson, L. B., Gregory, T. J. & Levitzky, M. G. (1985). The Influence of Arterial Chemoreceptor Stimulation on Hypoxic Pulmonary Vasoconstriction. (Vols. 44). (3), pp. 820. Fed Proc.

Gregory, T. J., Chapleau, M., Summer, W. R. & Levitzky, M. G. (1984). Aging Attenuates Hypoxic Pulmonary Vasoconstriction in Ferrets. (Vols. 32). (5), pp. 856. Clin Res.

Chapleau, M. W., Levitzky, M. G. (1984). Canine Heartworms (Dirofilaria immitis) Attenuate Hypoxic Pulmonary Vasoconstriction. (Vols. 27). (4), pp. 263. The Physiologist.

Chapleau, M. W., Gouaux, E. S. & Levitzky, M. G. (1984). The Effect of Carotid Body Chemoreceptor Stimulation on Pulmonary Blood Flow During Unilateral Alveolar Hypoxia. (Vols. 43). (4), pp. 921. Fed Proc.

Gregory, T. J., Chapleau, M., Summer, W. R. & Levitzky, M. G. (1984). The Effects of Aging on Hypoxic Pulmonary Vasoconstriction. (Vols. 27). (4), pp. 263. The Physiologist.

Hall, S. M., Chapleau, M., Cairo, J. & Levitzky, M. G. (1983). The Effect of High Frequency Ventilation on Halothane ablation of Hypoxic Pulmonary Vasoconstriction. (Vols. 42). (4), pp. 595. Fed Proc.

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Mark W. Chapleau, PhD

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Mark W. Chapleau, PhD

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