1. People

Allyn Mark, MD

Emeritus Professor of Internal Medicine-Cardiovascular Medicine

Current Positions

  • Emeritus Professor of Internal Medicine-Cardiovascular Medicine
  • Co-Founding Director, UI Obesity Research and Education Initiative (2011-2018)

Education

  • MD, University of Iowa College of Medicine, Iowa City, Iowa
  • Resident, Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
  • Resident, Medicine, The University of Iowa, Iowa City, Iowa
  • Fellow, Cardiology, The University of Iowa, Iowa City, Iowa

Center, Program and Institute Affiliations

Selected Publications

  • Young, C. N., Morgan, D. A., Butler, S. D., Rahmouni, K., Gurley, S. B., Coffman, T. M., Mark, A. L. & Davisson, R. L. (2015). Angiotensin type 1a receptors in the forebrain subfornical organ facilitate leptin-induced weight loss through brown adipose tissue thermogenesis. Molecular metabolism 4 (4) 337-43. DOI: 10.1016/j.molmet.2015.01.007. PMID: 25830096.
  • Hilzendeger, A. M., Cassell, M. D., Davis, D. R., Stauss, H. M., Mark, A. L., Grobe, J. L. & Sigmund, C. D. (2013). Angiotensin type 1a receptors in the subfornical organ are required for deoxycorticosterone acetate-salt hypertension. Hypertension (Dallas, Tex. : 1979) 61 (3) 716-22. DOI: 10.1161/HYPERTENSIONAHA.111.00356. PMID: 23266541.
  • Hilzendeger, A. M., Morgan, D. A., Brooks, L., Dellsperger, D., Liu, X., Grobe, J. L., Rahmouni, K., Sigmund, C. D. & Mark, A. L. (2012). A brain leptin-renin angiotensin system interaction in the regulation of sympathetic nerve activity. American journal of physiology. Heart and circulatory physiology 303 (2) H197-206. DOI: 10.1152/ajpheart.00974.2011. PMID: 22610169.
  • Harlan, S. M., Morgan, D. A., Agassandian, K., Guo, D. F., Cassell, M. D., Sigmund, C. D., Mark, A. L. & Rahmouni, K. (2011). Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation. Circulation research 108 (7) 808-12. DOI: 10.1161/CIRCRESAHA.111.240226. PMID: 21311043.
  • Ribeiro, A. C., Ceccarini, G., Dupré, C., Friedman, J. M., Pfaff, D. W. & Mark, A. L. (2011). Contrasting effects of leptin on food anticipatory and total locomotor activity. PloS one 6 (8) e23364. DOI: 10.1371/journal.pone.0023364. PMID: 21853117.
  • Grobe, J. L., Grobe, C. L., Beltz, T. G., Westphal, S. G., Morgan, D. A., Xu, D., de Lange, W. J., Li, H., Sakai, K., Thedens, D. R., Cassis, L. A., Rahmouni, K., Mark, A. L., Johnson, A. K. & Sigmund, C. D. (2010). The brain Renin-angiotensin system controls divergent efferent mechanisms to regulate fluid and energy balance. Cell metabolism 12 (5) 431-42. DOI: 10.1016/j.cmet.2010.09.011. PMID: 21035755.
  • Mark, A. L. (2009). Cardiovascular side effects of antiobesity drugs: a yellow flag in the race to safe pharmacotherapy for obesity. (Vols. 120). (9), pp. 719-21. Circulation. DOI: 10.1161/CIRCULATIONAHA.109.888529. PMID: 19687353.
  • Rahmouni, K., Sigmund, C. D., Haynes, W. G. & Mark, A. L. (2009). Hypothalamic ERK mediates the anorectic and thermogenic sympathetic effects of leptin. Diabetes 58 (3) 536-42. DOI: 10.2337/db08-0822. PMID: 19066310.
  • Mark, A. L. (2008). Dietary therapy for obesity: an emperor with no clothes. Hypertension (Dallas, Tex. : 1979) 51 (6) 1426-34; discussion 1434. DOI: 10.1161/HYPERTENSIONAHA.106.085944. PMID: 18474832.
  • Mark, A. L. (2007). Weight reduction for treatment of obesity-associated hypertension: nuances and challenges. Current hypertension reports 9 (5) 368-72. PMID: 18177582.

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