Mary E. Wilson, MD

Portrait
Professor of Internal Medicine - Infectious Diseases
Professor of Microbiology and Immunology
Professor of Epidemiology

Contact Information

Primary Office
401 EMRB
431 Newton Rd
Iowa City, IA 52242
319-356-3169

Lab
400 EMRB
431 Newton Rd
Iowa City, IA 52242
319-335-6808

Education

BA, Carleton College, Northfield, MN
MD, University of Rochester School of Medicine and Dentistry, Rochester, New York
Post Graduate, Bioinformatics, University of Iowa
Fellow, Infectious Diseases, University of Virginia, Charlottesville, VA
Resident, Internal Medicine, University of Michigan
Internship, Internal Medicine, University of Michigan

Licensure and Certifications

Certificate in Tropical Medicine and Travelers’ Health - American Society of Tropical Medicine and Hygiene
Subspecialty Board of Infectious Diseases - American Board of Internal Medicine
Medicine - Iowa Board of Medicine
- American Board of Internal Medicine
- National Board of Medical Examiners

Education/Training Program Affiliations

Biomedical Science Program, Department of Microbiology Graduate Program, Interdisciplinary Graduate Program in Genetics, Interdisciplinary Graduate Program in Immunology, Interdisciplinary Graduate Program in Molecular Medicine, Interdisciplinary Graduate Program in Translational Biomedicine, Medical Scientist Training Program

Center, Program and Institute Affiliations

Center for Gene Therapy of Cystic Fibrosis and other Genetic Diseases, Center for Immunology and Immune-based Diseases, Holden Comprehensive Cancer Center, Institute for Clinical and Translational Science, NIH Vaccine Treatment and Evaluation Unit

Research Summary

Dr. Wilson's research studies address the molecular, cellular and immunobiology of infection with the Leishmania species protozoa. Human infection with these parasites leads to a wide spectrum of clinical syndromes. Both human immunogenetic and parasite-encoded virulence factors lead to divergent disease manifestations. Dr. Wilson’s studies focus on the contributions of both host and parasite molecular characteristics that determine the outcome of leishmaniasis.

Leishmania are spread through the bite of a sand fly vector, and reside intracellularly in macrophages in human or other mammalian hosts. The parasite causes dramatic changes in gene expression in the host phagocyte, and lab members are investigating host mRNAs, host microRNAs and the parasite encoded virulence molecules underlying these changes. Other projects utilize both murine models and cultured human cells to address the contributions of macrophages, monocyte subsets, neutrophils, dendritic cells and keratinocytes to the local immune responses. The group hypothesizes that Leishmania manipulate the local immune response through the release of exosomes containing virulence-related proteins into the host environment. Techniques of protein chemistry, mass spectrometry, confocal microscopy, gene knockout/transgenic parasites and in vivo imaging of luminescent or fluorescent parasites are used to address these goals.

Dr. Wilson also participates in two Tropical Medicine Research Centers that fund collaborative field studies in India and Brazil. The Wilson lab works toward application of molecular techniques to understand both human genetic and molecular parasitic determinants leading to the diverse forms of human leishmaniasis. Genotyping of subjects in large family studies in India and Brazil has revealed several immune-related genes potentially associated with the outcome of visceral leishmaniasis. Studies of parasite genomes, and polymorphisms within genomes, are revealing contributions of the parasite strain to pathologic changes observed in leishmaniasis.

Publications

Yorek, M. S., Poudel, B., Mazgaeen, L., Pope, R. M., Wilson, M. E. & Gurung, P. (2019). Leishmania major degrades murine CXCL1 - An immune evasion strategy. PLoS Negl Trop Dis, 13(7), e0007533. PMID: 31260451.

Borbón, T. Y., Scorza, B. M., Clay, G. M., Lima Nobre de Queiroz, F., Sariol, A. J., Bowen, J. L., Chen, Y., Zhanbolat, B., Parlet, C. P., Valadares, D. G., Cassel, S. L., Nauseef, W. M., Horswill, A. R., Sutterwala, F. S. & Wilson, M. E. (2019). Coinfection with Leishmania major and Staphylococcus aureus enhances the pathologic responses to both microbes through a pathway involving IL-17A. PLoS Negl Trop Dis, 13(5), e0007247. PMID: 31107882.

Chakravarty, J., Hasker, E., Kansal, S., Singh, O. P., Malaviya, P., Singh, A. K., Chourasia, A., Singh, T., Sudarshan, M., Singh, A. P., Singh, B., Singh, R. P., Ostyn, B., Fakiola, M., Picado, A., Menten, J., Blackwell, J. M., Wilson, M. E., Sacks, D., Boelaert, M. & Sundar, S. (2019). Determinants for progression from asymptomatic infection to symptomatic visceral leishmaniasis: A cohort study. PLoS Negl Trop Dis, 13(3), e0007216. PMID: 30917114.

Lockard, R. D., Wilson, M. E. & Rodriguez, N. E. (2019). Sex-Related Differences in Immune Response and Symptomatic Manifestations to Infection with Leishmania Species. J Immunol Research, 2019, 4103819. PMID: 30756088.

Urak, K. T., Blanco, G. N., Shubham, S., Lin, L. H., Dassie, J. P., Thiel, W. H., Chen, Y., Sonkar, V. K., Lei, B., Murthy, S., Gutierrez, W. R., Wilson, M. E., Stiber, J. A., Klesney-Tait, J., Dayal, S., Miller, Jr, F. J. & Giangrande, P. H. (2019). RNA inhibitors of nuclear proteins responsible for multiple organ dysfunction syndrome. Nat Commun, 10(1), 116. PMID: 30631065.

Sousa, R., Andrade, V. M., Bair, T., Ettinger, N. A., Guimarães, L., Andrade, L., Guimarães, L. H., Machado, P. R., Carvalho, E. M., Wilson, M. E. & Schriefer, A. (2018). Early Suppression of Macrophage Gene Expression by Leishmania braziliensis. Front Microbiol, 9, 2464. PMID: 30374342.

Ozanne, M. V., Brown, G. D., Oleson, J. J., Lima, I. D., Queiroz, J. W., Jeronimo, S. M., Petersen, C. A. & Wilson, M. E. (2018). Bayesian compartmental model for an infectious disease with dynamic states of infection. Journal of Applied Statistics, 46(6), 1043-1065. DOI: 10.1080/02664763.2018.1531979.

Marshall, S., Kelly, P. H., Singh, B. K., Pope, R. M., Kim, P., Zhanbolat, B., Wilson, M. E. & Yao, C. (2018). Extracellular release of virulence factor major surface protease via exosomes in Leishmania infantum promastigotes. Parasit Vectors, 11(1), 355. PMID: 29921321.

Lago, A. S., Nascimento, M., Carvalho, A. M., Lago, N., Silva, J., Queiroz, J. R., Carvalho, L. P., Schriefer, A., Wilson, M. E., Machado, P. & Carvalho, E. M. (2018). The Elderly Respond to Antimony Therapy for Cutaneous Leishmaniasis Similarly to Young Patients but have Severe Adverse Reactions. Am J Trop Med Hyg, 98(5), 1317-1324. PMID: 29582733.

Lima, I. D., Lima, A. L., Mendes-Aguiar, C. O., Coutinho, J. F., Wilson, M. E., Pearson, R. D., Queiroz, J. W. & Jeronimo, S. M. (2018). Changing demographics of visceral leishmaniasis in northeast Brazil: Lessons for the future. PLoS Negl Trop Dis, 12(3), e0006164. PMID: 29509765.

Hornick, E. E., Banoth, B., Miller, A. M., Zacharias, Z. R., Jain, N., Wilson, M. E., Gibson-Corley, K. N., Legge, K. L., Bishop, G. A., Sutterwala, F. S. & Cassel, S. L. (2018). Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection. J Immunol, 200(3), 1188-1197. PMID: 29282312.

Rodríguez, N. E., Lima, I. D., Gaur Dixit, U., Turcotte, E. A., Lockard, R. D., Batra-Sharma, H., Nascimento, E. L., Jeronimo, S. M. & Wilson, M. E. (2018). Epidemiological and Experimental Evidence for Sex-Dependent Differences in the Outcome of Leishmania infantum Infection. Am J Trop Med Hyg, 98(1), 142-145. PMID: 29165220.

Silva, J., Queiroz, A., Moura, I., Sousa, R. S., Guimarães, L. H., Machado, P. R., Lessa, M., Lago, E., Wilson, M. E. & Schriefer, A. (2017). Dynamics of American tegumentary leishmaniasis in a highly endemic region for Leishmania (Viannia) braziliensis infection in northeast Brazil. PLoS Negl Trop Dis, 11(11), e0006015. PMID: 29095818.

Clay, G. M., Valadares, D. G., Graff, J. W., Ulland, T. K., Davis, R. E., Scorza, B. M., Zhanbolat, B. S., Chen, Y., Sutterwala, F. S. & Wilson, M. E. (2017). An Anti-Inflammatory Role for NLRP10 in Murine Cutaneous Leishmaniasis. J Immunol, 199(8), 2823-2833. PMID: 28931602.

Scorza, B. M., Wacker, M. A., Messingham, K., Kim, P., Klingelhutz, A., Fairley, J. & Wilson, M. E. (2017). Differential Activation of Human Keratinocytes by Leishmania Species Causing Localized or Disseminated Disease. J Invest Dermatol, 137(10), 2149-2156. PMID: 28647347.

Lima, A. L., de Lima, I. D., Coutinho, J. F., de Sousa, U. P., Rodrigues, M. A., Wilson, M. E., Pearson, R. D., Queiroz, J. W. & Jerônimo, S. M. (2017). Changing epidemiology of visceral leishmaniasis in northeastern Brazil: a 25-year follow-up of an urban outbreak. Trans R Soc Trop Med Hyg, 111(10), 440-447. PMID: 29394411.

Lima, A. L., de Lima, I. D., Coutinho, J. F., de Sousa, U. P., Rodrigues, M. A., Wilson, M. E., Pearson, R. D., Queiroz, J. W. & Jeronimo, S. M. (2017). Changing epidemiology of visceral leishmaniasis in northeastern Brazil: a 25-year follow-up of an urban outbreak. Trans R Soc Trop Med Hyg, 111(10), 440-447. PMID: 29394411.

Teixeira, D. G., Monteiro, G. R., Martins, D. R., Fernandes, M. Z., Macedo-Silva, V., Ansaldi, M., Nascimento, P. R., Kurtz, M. A., Streit, J. A., Ximenes, M. F., Pearson, R. D., Miles, A., Blackwell, J. M., Wilson, M. E., Kitchen, A., Donelson, J. E., Lima, J. P. & Jeronimo, S. M. (2017). Comparative analyses of whole genome sequences of Leishmania infantum isolates from humans and dogs in northeastern Brazil. Int J Parasitol, 47(10-11), 655-665. PMID: 28606698.

Sharma, S., Srivastva, S., Davis, R. E., Singh, S. S., Kumar, R., Nylén, S., Wilson, M. E. & Sundar, S. (2017). The Phenotype of Circulating Neutrophils during Visceral Leishmaniasis. Am J Trop Med Hyg, 97(3), 767-770. PMID: 28820688.

Rodríguez, N. E., Lockard, R. D., Turcotte, E. A., Araújo-Santos, T., Bozza, P. T., Borges, V. M. & Wilson, M. E. (2017). Lipid bodies accumulation in Leishmania infantum-infected C57BL/6 macrophages. Parasite Immunol, 39(8). PMID: 28518475.

Christiaansen, A. F., Dixit, U. G., Coler, R. N., Marie Beckmann, A., Reed, S. G., Winokur, P. L., Zimmerman, M. B., Varga, S. M. & Wilson, M. E. (2017). CD11a and CD49d enhance the detection of antigen-specific T cells following human vaccination. Vaccine, 35(33), 4255-4261. PMID: 28662951.

Scorza, B. M., Carvalho, E. M. & Wilson, M. E. (2017). Cutaneous Manifestations of Human and Murine Leishmaniasis. Int J Mol Sci, 18(6), E1296. PMID: 28629171.

Tucker, J. D., Hughes, M. A., Durvasula, R. V., Vinetz, J. M., McGovern, V. P., Schultz, R., Dunavan, C. P., Wilson, M. E., Milner, D. A., LaRocque, R. C., Calderwood, S. B., Guerrant, R. L., Weller, P. F. & Taylor, T. E. (2017). Measuring Success in Global Health Training: Data From 14 Years of a Postdoctoral Fellowship in Infectious Diseases and Tropical Medicine. Clin Infect Dis, 64(12), 1768-1772. PMID: 28369324.

Davis, R. E., Sharma, S., Conceição, J., Carneiro, P., Novais, F., Scott, P., Sundar, S., Bacellar, O., Carvalho, E. M. & Wilson, M. E. (2017). Phenotypic and functional characteristics of HLA-DR+ neutrophils in Brazilians with cutaneous leishmaniasis. J Leukoc Biol, 101(3), 739-749. PMID: 28076241.

Kelly, P. H., Bahr, S. M., Serafim, T. D., Ajami, N. J., Petrosino, J. F., Meneses, C., Kirby, J. R., Valenzuela, J. G., Kamhawi, S. & Wilson, M. E. (2017). The Gut Microbiome of the Vector Lutzomyia longipalpis Is Essential for Survival of Leishmania infantum. MBio, 8(1), e01121-16. PMID: 28096483.

Weirather, J. L., Duggal, P., Nascimento, E. L., Monteiro, G. R., Martins, D. R., Lacerda, H. G., Fakiola, M., Blackwell, J. M., Jeronimo, S. M. & Wilson, M. E. (2017). Comprehensive candidate gene analysis for symptomatic or asymptomatic outcomes of Leishmania infantum infection in Brazil. Ann Hum Genet, 81(1), 41-48. PMID: 28054334.

Guimarães, L. H., Queiroz, A., Silva, J. A., Silva, S. C., Magalhães, V., Lago, E. L., Machado, P. R., Bacellar, O., Wilson, M. E., Beverley, S. M., Carvalho, E. M. & Schriefer, A. (2016). Atypical Manifestations of Cutaneous Leishmaniasis in a Region Endemic for Leishmania braziliensis: Clinical, Immunological and Parasitological Aspects. PLoS Negl Trop Dis, 10(12), e0005100. PMID: 27906988.

Sharma, S., Davis, R. E., Srivastva, S., Nylén, S., Sundar, S. & Wilson, M. E. (2016). A Subset of Neutrophils Expressing Markers of Antigen-Presenting Cells in Human Visceral Leishmaniasis. J Infect Dis, 214(10), 1531-1538. PMID: 27601622.

Ulland, T. K., Jain, N., Hornick, E. E., Elliott, E. I., Clay, G. M., Sadler, J. J., Mills, K. A., Janowski, A. M., Volk, A. P., Wang, K., Legge, K. L., Gakhar, L., Bourdi, M., Ferguson, P. J., Wilson, M. E., Cassel, S. L. & Sutterwala, F. S. (2016). Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment. Nat Commun, 7, 13180. PMID: 27779193.

Medina, L. S., Souza, B. A., Queiroz, A., Guimarães, L. H., Lima Machado, P. R., Carvalho, E., Wilson, M. E. & Schriefer, A. (2016). The gp63 Gene Cluster Is Highly Polymorphic in Natural Leishmania (Viannia) braziliensis Populations, but Functional Sites Are Conserved. PLoS One, 11(9), e0163284. PMID: 27648939.

Weirather, J. L., Duggal, P., Nascimento, E. L., Monteiro, G. R., Martins, D. R., Lacerda, H. G., Fakiola, M., Blackwell, J. M., Jeronimo, S. M. & Wilson, M. E. (2016). Fine mapping under linkage peaks for symptomatic or asymptomatic outcomes of Leishmania infantum infection in Brazil. Infect Genet Evol, 43, 1-5. PMID: 27155051.

Sudan, B., Wacker, M. A., Wilson, M. E. & Graff, J. W. (2016). A Systematic Approach to Identify Markers of Distinctly Activated Human Macrophages. Front Immunol, 6, 253. PMID: 26074920.

Schaut, R. G., Lamb, I. M., Toepp, A. J., Scott, B., Mendes-Aguiar, C. O., Coutinho, J. F., Jeronimo, S. M., Wilson, M. E., Harty, J. T., Waldschmidt, T. J. & Petersen, C. A. (2016). Regulatory IgDhi B Cells Suppress T Cell Function via IL-10 and PD-L1 during Progressive Visceral Leishmaniasis. J Immunol, 196(10), 4100-9. PMID: 27076677.

Conceição, J., Davis, R., Carneiro, P. P., Giudice, A., Muniz, A. C., Wilson, M. E., Carvalho, E. M. & Bacellar, O. (2016). Characterization of Neutrophil Function in Human Cutaneous Leishmaniasis Caused by Leishmania braziliensis. PLoS Negl Trop Dis, 10(5), e0004715. PMID: 27167379.

Davis, R. E., Thalhofer, C. J. & Wilson, M. E. (2016). Infection and Activation of Human Neutrophils with Fluorescent Leishmania infantum. J Immunol Tech Infect Dis, 5(3). DOI: 10.4172/2329-9541.1000146.

Yao, C., Wilson, M. E. (2016). Dynamics of sterol synthesis during development of Leishmania spp. parasites to their virulent form. Parasit Vectors, 9, 200. PMID: 27071464.

Dupnik, K. M., Bair, T. B., Maia, A. O., Amorim, F. M., Costa, M. R., Keesen, T. S., Valverde, J. G., Queiroz, M. D., Medeiros, L. L., de Lucena, N. L., Wilson, M. E., Nobre, M. L., Johnson, W. D. & Jeronimo, S. M. (2015). Transcriptional changes that characterize the immune reactions of leprosy. J Infect Dis, 211(10), 1658-76. PMID: 25398459.

Araújo-Santos, T., Rodríguez, N. E., Moura-Pontes, S., Dixt, U. G., Abánades, D. R., Bozza, P. T., Wilson, M. E. & Borges, V. M. (2014). Role of Prostaglandin F2a Production in Lipid Bodies From Leishmania infantum chagasi: Insights on Virulence. J Infect Dis, 210(12), 1951-61. PMID: 24850789.

Sudarshan, M., Singh, T., Singh, A. K., Chourasia, A., Singh, B., Wilson, M. E., Chakravarty, J. & Sundar, S. (2014). Quantitative PCR in epidemiology for early detection of visceral leishmaniasis cases in India. PLoS Negl Trop Dis, 8(12), e3366. PMID: 25503103.

Dassie, J. P., Hernandez, L. I., Thomas, G. S., Long, M. E., Rockey, W. M., Howell, C. A., Chen, Y., Hernandez, F. J., Liu, X. Y., Wilson, M. E., Allen, L. H., Vaena, D. A., Meyerholz, D. K. & Giangrande, P. H. (2014). Targeted Inhibition of Prostate Cancer Metastases with an RNA Aptamer to Prostate-specific Membrane Antigen. Mol Ther, 22(11), 1910-22. PMID: 24954476.

de Morais, S. M., Vila-Nova, N. S., Bevilaqua, C. M., Rondon, F. C., Lobo, C. H., de Alencar Araripe Noronha Moura, A., Sales, A. D., Rodrigues, A. P., de Figuereido, J. R., Campello, C. C., Wilson, M. E. & de Andrade Jr., H. F. (2014). Thymol and eugenol derivatives as potential antileishmanial agents. Bioorg Med Chem, 22(21), 6250-5. PMID: 25281268.

Eigsti, R. L., Sudan, B., Wilson, M. E. & Graff, J. W. (2014). Regulation of Activation-associated MicroRNA Accumulation Rates during Monocyte-to-macrophage Differentiation. J Biol Chem, 289(41), 28433-47. PMID: 25148686.

Rodríguez, N. E., Wilson, M. E. (2014). Eosinophils and mast cells in leishmaniasis. Immunol Res, 59(1-3), 129-41. PMID: 24838146.

Clay, G. M., Sutterwala, F. S. & Wilson, M. E. (2014). NLR proteins and parasitic disease. Immunol Res, 59(1-3), 142-52. PMID: 24989828.

Hasker, E., Malaviya, P., Gidwani, K., Picado, A., Ostyn, B., Kansal, S., Singh, R. P., Singh, O. P., Chourasia, A., Kumar Singh, A., Shankar, R., Wilson, M. E., Khanal, B., Rijal, S., Boelaert, M. & Sundar, S. (2014). Strong association between serological status and probability of progression to clinical visceral leishmaniasis in prospective cohort studies in India and Nepal. PLoS Negl Trop Dis, 8(1), e2657. PMID: 24466361.

Macedo-Silva, V. P., Martins, D. R., De Queiroz, P. V., Pinheiro, M. P., Freier, C. C., Queiroz, J. W., Dupnik, K. M., Pearson, R. D., Wilson, M. E., Jeronimo, S. M. & Ximenes Mde, F. (2014). Feeding preferences of Lutzomyia longipalpis (Diptera: Psychodidae), the sand fly vector, for Leishmania infantum (Kinetoplastida: Trypanosomatidae). J Med Entomol, 51(1), 237-44. PMID: 24605474.

D'Antonio, E. L., Ullman, B., Roberts, S. C., Dixit, U. G., Wilson, M. E., Hai, Y. & Christianson, D. W. (2013). Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections. Arch Biochem Biophys, 535(2), 163-76. PMID: 23583962.

Yao, C., Gaur Dixit, U., Barker, J. H., Teesch, L. M., Love-Homan, L., Donelson, J. E. & Wilson, M. E. (2013). Attenuation of Leishmania infantum chagasi metacyclic promastigotes by sterol depletion. Infect Immun, 81(7), 2507-17. PMID: 23630964.

Novais, F. O., Carvalho, L. P., Graff, J. W., Beiting, D. P., Ruthel, G., Roos, D. S., Betts, M. R., Goldschmidt, M. H., Wilson, M. E., de Oliveira, C. I. & Scott, P. (2013). Cytotoxic T cells mediate pathology and metastasis in cutaneous leishmaniasis. PLoS Pathog, 9(7), e1003504. PMID: 23874205.

Polando, R., Dixit, U. G., Carter, C. R., Jones, B., Whitcomb, J. P., Ballhorn, W., Harintho, M., Jerde, C. L., Wilson, M. E. & McDowell, M. A. (2013). The roles of complement receptor 3 and Fc? receptors during Leishmania phagosome maturation. J Leukoc Biol, 93(6), 921-32. PMID: 23543768.

Vila-Nova, N. S., de Morais, S. M., Falcão, M. J., Alcantara, T. T., Ferreira, P. A., Cavalcanti, E. S., Vieira, I. G., Campello, C. C. & Wilson, M. E. (2013). Different susceptibilities of Leishmania spp. promastigotes to the Annona muricata acetogenins annonacinone and corossolone, and the Platymiscium floribundum coumarin scoparone. Exp Parasitol, 133(3), 334-8. PMID: 23232251.

LeishGEN Consortium,, Wellcome Trust Case Control Consortium 2,, Fakiola, M., Strange, A., Cordell, H. J., Miller, E. N., Pirinen, M., Su, Z., Mishra, A., Mehrotra, S., Monteiro, G. R., Band, G., Bellenguez, C., Dronov, S., Edkins, S., Freeman, C., Giannoulatou, E., Gray, E., Hunt, S. E., Lacerda, H. G., Langford, C., Pearson, R., Pontes, N. N., Rai, M., Singh, S. P., Smith, L., Sousa, O., Vukcevic, D., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Wilson, M. E., Deloukas, P., Peltonen, L., Christiansen, F., Witt, C., Jeronimo, S. M., Sundar, S., Spencer, C. C., Blackwell, J. M. & Donnelly, P. (2013). Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. Nat Genet, 45(2), 208-13. PMID: 23291585.

Hasker, E., Kansal, S., Malaviya, P., Gidwani, K., Picado, A., Singh, R. P., Chourasia, A., Singh, A. K., Shankar, R., Menten, J., Wilson, M. E., Boelaert, M. & Sundar, S. (2013). Latent infection with Leishmania donovani in highly endemic villages in Bihar, India. PLoS Negl Trop Dis, 7(2), e2053. PMID: 23459501.

Queiroz, A., Sousa, R., Heine, C., Cardoso, M., Guimarães, L. H., Machado, P. R., Carvalho, E. M., Riley, L. W., Wilson, M. E. & Schriefer, A. (2012). Association between an emerging disseminated form of leishmaniasis and Leishmania (Viannia) braziliensis strain polymorphisms. J Clin Microbiol, 50(12), 4028-34. PMID: 23035200.

Wendlandt, E. B., Graff, J. W., Gioannini, T. L., McCaffrey, A. P. & Wilson, M. E. (2012). The role of microRNAs miR-200b and miR-200c in TLR4 signaling and NF-?B activation. Innate Immun, 18(6), 846-55. PMID: 22522429.

Vila-Nova, N. S., Morais, S. M., Falcão, M. J., Bevilaqua, C. M., Rondon, F. C., Wilson, M. E., Vieira, I. G. & Andrade, H. F. (2012). Leishmanicidal and cholinesterase inhibiting activities of phenolic compounds of Dimorphandra gardneriana and Platymiscium floribundum, native plants from Caatinga biome. Pesq Vet Bras, 32(11), 1164-8.

Ueno, N., Wilson, M. E. (2012). Receptor-mediated phagocytosis of Leishmania: implications for intracellular survival. Trends Parasitol, 28(8), 335-44. PMID: 22726697.

Graff, J. W., Dickson, A. M., Clay, G., McCaffrey, A. P. & Wilson, M. E. (2012). Identifying functional microRNAs in macrophages with polarized phenotypes. J Biol Chem, 287(26), 21816-25. PMID: 22549785.

Bruhn, K. W., Birnbaum, R., Haskell, J., Vanchinathan, V., Greger, S., Narayan, R., Chang, P. L., Tran, T. A., Hickerson, S. M., Beverley, S. M., Wilson, M. E. & Craft, N. (2012). Killed but metabolically active Leishmania infantum as a novel whole-cell vaccine for visceral leishmaniasis. Clin Vaccine Immunol, 19(4), 490-8. PMID: 22323556.

Weirather, J. L., Wilson, M. E. & Donelson, J. E. (2012). Mapping of VSG similarities in Trypanosoma brucei. Mol Biochem Parasitol, 181(2), 141-52. PMID: 22079099.

Graff, J. W., Powers, L. S., Dickson, A. M., Kim, J., Reisetter, A. C., Hassan, I. H., Kremens, K., Gross, T. J., Wilson, M. E. & Monick, M. M. (2012). Cigarette smoking decreases global microRNA expression in human alveolar macrophages. PloS One, 7(8), e44066. PMID: 22952876.

Ramírez, C., Díaz-Toro, Y., Tellez, J., Castilho, T. M., Rojas, R., Ettinger, N. A., Tikhonova, I., Alexander, N. D., Valderrama, L., Hager, J., Wilson, M. E., Lin, A., Zhao, H., Saravia, N. G. & McMahon-Pratt, D. (2012). Human macrophage response to L. (Viannia) panamensis: microarray evidence for an early inflammatory response. PLoS Negl Trop Dis, 6(10), e1866. PMID: 23145196.

Lima, I. D., Queiroz, J. W., Lacerda, H. G., Queiroz, P. V., Pontes, N. N., Barbosa, J. D., Martins, D. R., Weirather, J. L., Pearson, R. D., Wilson, M. E. & Jeronimo, S. M. (2012). Leishmania infantum chagasi in northeastern Brazil: asymptomatic infection at the urban perimeter. Am J Trop Med Hyg, 86(1), 99-107. PMID: 22232458.

Weirather, J. L., Jeronimo, S. M., Gautam, S., Sundar, S., Kang, M., Kurtz, M. A., Haque, R., Schriefer, A., Talhari, S., Carvalho, E. M., Donelson, J. E. & Wilson, M. E. (2011). Serial quantitative PCR assay for detection, species discrimination, and quantification of Leishmania spp. in human samples. J Clin Microbiol, 49(11), 3892-904. PMID: 22042830.

Hsiao, C. H., Ueno, N., Shao, J. Q., Schroeder, K. R., Moore, K. C., Donelson, J. E. & Wilson, M. E. (2011). The effects of macrophage source on the mechanism of phagocytosis and intracellular survival of Leishmania. Microbes Infect, 13(12-13), 1033-44. PMID: 21723411.

Sudarshan, M., Weirather, J. L., Wilson, M. E. & Sundar, S. (2011). Study of parasite kinetics with antileishmanial drugs using real-time quantitative PCR in Indian visceral leishmaniasis. J Antimicrob Chemother, 66(8), 1751-5. PMID: 21609983.

Nascimento, E. T., Moura, M. L., Queiroz, J. W., Barroso, A. W., Araujo, A. F., Rego, E. F., Wilson, M. E., Pearson, R. D. & Jeronimo, S. M. (2011). The emergence of concurrent HIV-1/AIDS and visceral leishmaniasis in Northeast Brazil. Trans R Soc Trop Med Hyg, 105(5), 298-300. PMID: 21474157.

Rodríguez, N. E., Gaur Dixit, U., Allen, L. A. & Wilson, M. E. (2011). Stage-specific pathways of Leishmania infantum chagasi entry and phagosome maturation in macrophages. PLoS One, 6(4), e19000. PMID: 21552562.

Thalhofer, C. J., Chen, Y., Sudan, B., Love-Homan, L. & Wilson, M. E. (2011). Leukocytes infiltrate the skin and draining lymph nodes in response to the protozoan Leishmania infantum chagasi. Infect Immun, 79(1), 108-17. PMID: 20937764.

DebRoy, S., Keenan, A. B., Ueno, N., Jeronimo, S. M., Donelson, J. E. & Wilson, M. E. (2010). Leishmania infantum chagasi: a genome-based approach to identification of excreted/secreted proteins. Exp Parasitol, 126(4), 582-91. PMID: 20542033.

Bruhn, K. W., Marathe, C., Maretti-Mira, A. C., Nguyen, H., Haskell, J., Tran, T. A., Vanchinathan, V., Gaur, U., Wilson, M. E., Tontonoz, P. & Craft, N. (2010). LXR deficiency confers increased protection against visceral Leishmania infection in mice. PLoS Negl Trop Dis, 4(11), e886. PMID: 21103366.

Thalhofer, C. J., Graff, J. W., Love-Homan, L., Hickerson, S. M., Craft, N., Beverley, S. M. & Wilson, M. E. (2010). In vivo imaging of transgenic Leishmania parasites in a live host. J Vis Exp,(41), 1980. PMID: 20689512.

Souza, A. S., Giudice, A., Pereira, J. M., Guimarães, L. H., de Jesus, A. R., de Moura, T. R., Wilson, M. E., Carvalho, E. M. & Almeida, R. P. (2010). Resistance of Leishmania (Viannia) braziliensis to nitric oxide: correlation with antimony therapy and TNF-alpha production. BMC Infect Dis, 10, 209. PMID: 20633260.

Ramasawmy, R., Menezes, E., Magalhães, A., Oliveira, J., Castellucci, L., Almeida, R., Rosa, M. E., Guimarães, L. H., Lessa, M., Noronha, M., Wilson, M. E., Jamieson, S. E., Kalil, J., Blackwell, J. M., Carvalho, E. M. & de Jesus, A. R. (2010). The -2518 A/G promoter polymorphism in the gene (CCL2/ MCP1) encoding monocyte chemotactic protein 1 influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil. Infect Genet Evol, 10(5), 607-13. PMID: 20430117.

Yao, C., Li, Y., Donelson, J. E. & Wilson, M. E. (2010). Proteomic examination of Leishmania chagasi plasma membrane proteins: Contrast between avirulent and virulent (metacyclic) parasite forms. Proteomics Clin Appl, 4(1), 4-16. PMID: 21137013.

Ueno, N., Bratt, C. L., Rodriguez, N. E. & Wilson, M. E. (2009). Differences in human macrophage receptor usage, lysosomal fusion kinetics and survival between logarithmic and metacyclic Leishmania infantum chagasi promastigotes. Cell Microbiol, 11(12), 1827-41. PMID: 19702651.

Gaur, U., Showalter, M., Hickerson, S., Dalvi, R., Turco, S. J., Wilson, M. E. & Beverley, S. M. (2009). Leishmania donovani lacking the Golgi GDP-Man transporter LPG2 exhibit attenuated virulence in mammalian hosts. Exp Parasitol, 122(3), 182-91. PMID: 19328787.

Ettinger, N. A., Duggal, P., Braz, R. F., Nascimento, E. T., Beaty, T. H., Jeronimo, S. M., Pearson, R. D., Blackwell, J. M., Moreno, L. & Wilson, M. E. (2009). Genetic admixture in Brazilians exposed to infection with Leishmania chagasi. Ann Hum Genet, 73(Pt 3), 304-13. PMID: 19397557.

Blackwell, J. M., Fakiola, M., Ibrahim, M. E., Jamieson, S. E., Jeronimo, S. B., Miller, E. N., Mishra, A., Mohamed, H. S., Peacock, C. S., Raju, M., Sundar, S. & Wilson, M. E. (2009). Genetics and visceral leishmaniasis: of mice and man. Parasite Immunol, 31(5), 254-66. PMID: 19388946.

Boitz, J. M., Yates, P. A., Kline, C., Gaur, U., Wilson, M. E., Ullman, B. & Roberts, S. C. (2009). Leishmania donovani ornithine decarboxylase is indispensable for parasite survival in the mammalian host. Infect Immun, 77(2), 756-63. PMID: 19064633.

Helm, J. R., Wilson, M. E. & Donelson, J. E. (2009). Differential expression of a protease gene family in African trypanosomes. Mol Biochem Parasitol, 163(1), 8-18. PMID: 18848586.

Haleem, A., Wilson, M. E. (2009). Visceral Leishmaniasis (Kala Azar). In A. Satoskar , G. Simon , P. Hotez , M. Tsuji (Eds.) Medical Parasitology (Vademecum). Landes Bioscience.

Schriefer, A., Wilson, M. E. & Carvalho, E. M. (2008). Recent developments leading toward a paradigm switch in the diagnostic and therapeutic approach to human leishmaniasis. Curr Opin Infect Dis, 21(5), 483-8. PMID: 18725797.

Ettinger, N. A., Wilson, M. E. (2008). Macrophage and T-cell gene expression in a model of early infection with the protozoan Leishmania chagasi. PLoS Negl Trop Dis, 2(6), e252. PMID: 18575603.

Helm, J. R., Wilson, M. E. & Donelson, J. E. (2008). Different trans RNA splicing events in bloodstream and procyclic Trypanosoma brucei. Mol Biochem Parasitol, 159(2), 134-7. PMID: 18384893.

Hsiao, C. H., Yao, C., Storlie, P., Donelson, J. E. & Wilson, M. E. (2008). The major surface protease (MSP or GP63) in the intracellular amastigote stage of Leishmania chagasi. Mol Biochem Parasitol, 157(2), 148-59. PMID: 18067978.

Wilson, M. E. (2008). Giardiasis. In R. B. Wallace (Eds.) Wallace/Maxcy-Rosenau-Last public health & preventive medicine. (15th edtion), pp. chapter 13. New York: McGraw-Hill Medical.

Wilson, M. E. (2008). Leishmaniasis. In R. Wallace (Eds.) Wallace/Maxcy-Rosenau-Last public health & preventive medicine. (15th edition), pp. Chapter 15. New York: McGraw-Hill Medical.

Blackwell, J. M., McMahon-Pratt, D. & Wilson, M. E. (2008). Impact of the Leishmania genome on vaccine development. In P. J. Myler , N. Fasel (Eds.) Leishmania: After the Genome. Caister Academic Press.

Yao, C., Chen, Y., Sudan, B., Donelson, J. E. & Wilson, M. E. (2008). Leishmania chagasi: homogenous metacyclic promastigotes isolated by buoyant density are highly virulent in a mouse model. Exp Parasitol, 118(1), 129-33. PMID: 17706646.

Duarte, I., Maciel, B. L., Monteiro, G. R., Queiroz, J. W., Nascimento, E. T., Lacerda, H. G., Braz, R. F., Sousa, O. N., Ximenes, M. F., Sampaio, G. A., Gomes, C. E., Pontes, N. N., Martins, D. R., Blackwell, J. M., Wilson, M. E., Pearson, R. D. & Jeronimo, S. M. (2008). Risk factors associated with Leishmania infection and the development of visceral leishmaniasis. Revista da Sociedade Brasileira de Medicina Tropical, 41(Suppl 3), 168-71.

Gaur, U., Roberts, S. C., Dalvi, R. P., Corraliza, I., Ullman, B. & Wilson, M. E. (2007). An effect of parasite-encoded arginase on the outcome of murine cutaneous leishmaniasis. J Immunol, 179(12), 8446-53. PMID: 18056391.

Grandgenett, P. M., Otsu, K., Wilson, H. R., Wilson, M. E. & Donelson, J. E. (2007). A function for a specific zinc metalloprotease of African trypanosomes. PLoS Pathog, 3(10), 1432-45. PMID: 17953481.

Jeronimo, S. M., Duggal, P., Ettinger, N. A., Nascimento, E. T., Monteiro, G. R., Cabral, A. P., Pontes, N. N., Lacerda, H. G., Queiroz, P. V., Gomes, C. E., Pearson, R. D., Blackwell, J. M., Beaty, T. H. & Wilson, M. E. (2007). Genetic predisposition to self-curing infection with the protozoan Leishmania chagasi: a genome wide scan. J Infect Dis, 196(8), 1261-9. PMID: 17955446.

Jeronimo, S. M., Holst, A. K., Jamieson, S. E., Francis, R., Martins, D. R., Bezerra, F. L., Ettinger, N. A., Nascimento, E. T., Monteiro, G. R., Lacerda, H. G., Miller, E. N., Cordell, H. J., Duggal, P., Beaty, T. H., Blackwell, J. M. & Wilson, M. E. (2007). Genes at human chromosome 5q31.1 regulate delayed-type hypersensitivity responses associated with Leishmania chagasi infection. Genes Immun, 8(7), 539-51. PMID: 17713557.

Yao, C., Donelson, J. E. & Wilson, M. E. (2007). Internal and surface-localized major surface proteases of Leishmania spp. and their differential release from promastigotes. Eukaryot Cell, 6(10), 1905-12. PMID: 17693594.

Yao, C., Luo, J., Hsiao, C. H., Donelson, J. E. & Wilson, M. E. (2007). Leishmania chagasi: a tetracycline-inducible cell line driven by T7 RNA polymerase. Exp Parasitol, 116(3), 205-13. PMID: 17320870.

Giudice, A., Camada, I., Leopoldo, P. T., Pereira, J. M., Riley, L. W., Wilson, M. E., Ho, J. L., de Jesus, A. R., Carvalho, E. M. & Almeida, R. P. (2007). Resistance of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensis to nitric oxide correlates with disease severity in Tegumentary Leishmaniasis. BMC infect Dis, 7, 7. PMID: 17316450.

Chang, H. K., Thalhofer, C., Duerkop, B. A., Mehling, J. S., Verma, S., Gollob, K. J., Almeida, R. & Wilson, M. E. (2007). Oxidant generation by single infected monocytes after short-term fluorescence labeling of a protozoan parasite. Infect Immun, 75(2), 1017-24. PMID: 17118986.

Jamieson, S. E., Miller, E. N., Peacock, C. S., Fakiola, M., Wilson, M. E., Bales-Holst, A., Shaw, M. A., Silveira, F., Shaw, J. J., Jeronimo, S. M. & Blackwell, J. M. (2007). Genome-wide scan for visceral leishmaniasis susceptibility genes in Brazil. Genes Immun, 8(1), 84-90. PMID: 17122780.

Martins, D. R., Jeronimo, S. M., Donelson, J. E. & Wilson, M. E. (2006). Leishmania chagasi T-cell antigens identified through a double library screen. Infect Immun, 74(12), 6940-8. PMID: 17000724.

Castellucci, L., Menezes, E., Oliveira, J., Magalhaes, A., Guimaraes, L. H., Lessa, M., Ribeiro, S., Reale, J., Noronha, E. F., Wilson, M. E., Duggal, P., Beaty, T. H., Jeronimo, S., Jamieson, S. E., Bales, A., Blackwell, J. M., de Jesus, A. R. & Carvalho, E. M. (2006). IL6 -174 G/C promoter polymorphism influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil. J Infect Dis, 194(4), 519-27. PMID: 16845637.

Rodríguez, N. E., Gaur, U. & Wilson, M. E. (2006). Role of caveolae in Leishmania chagasi phagocytosis and intracellular survival in macrophages. Cell Microbiol, 8(7), 1106-20. PMID: 16819964.

Aleixo, J. A., Nascimento, E. T., Monteiro, G. R., Fernandes, M. Z., Ramos, A. M., Wilson, M. E., Pearson, R. D. & Jeronimo, S. M. (2006). Atypical American visceral leishmaniasis caused by disseminated Leishmania amazonensis infection presenting with hepatitis and adenopathy. Trans R Soc Trop Med Hyg, 100(1), 79-82. PMID: 16198385.

Castellucci, L., Cheng, L. H., Araújo, C., Guimarães, L. H., Lessa, H., Machado, P., Almeida, M. F., Oliveira, A., Ko, A., Johnson, W. D., Wilson, M. E., Carvalho, E. M. & DE Jesus, A. R. (2005). Familial aggregation of mucosal leishmaniasis in northeast Brazil. Am J Trop Med Hyg, 73(1), 69-73. PMID: 16014836.

Purdy, J. E., Donelson, J. E. & Wilson, M. E. (2005). Regulation of genes encoding the major surface protease of Leishmania chagasi via mRNA stability. Mol Biochem Parasitol, 142(1), 88-97. PMID: 15876463.

Purdy, J. E., Donelson, J. E. & Wilson, M. E. (2005). Leishmania chagasi: the alpha-tubulin intercoding region results in constant levels of mRNA abundance despite protein synthesis inhibition and growth state. Exp Parasitol, 110(2), 102-7. PMID: 15888291.

Wilson, M. E., Jeronimo, S. M. & Pearson, R. D. (2005). Immunopathogenesis of infection with the visceralizing Leishmania species. Microb Pathog, 38(4), 147-60. PMID: 15797810.

Yao, C., Luo, J., Hsiao, C., Donelson, J. E. & Wilson, M. E. (2005). Internal and surface subpopulations of the major surface protease (MSP) of Leishmania chagasi. Mol Biochem Parasitol, 139(2), 173-83. PMID: 15664652.

Yao, C., Luo, J., Storlie, P., Donelson, J. E. & Wilson, M. E. (2004). Multiple products of the Leishmania chagasi major surface protease (MSP or GP63) gene family. Mol Biochem Parasitol, 135(2), 171-83. PMID: 15110459.

Rodriguez, N. E., Chang, H. K. & Wilson, M. E. (2004). Novel program of macrophage gene expression induced by phagocytosis of Leishmania chagasi. Infect Immun, 72(4), 2111-22. PMID: 15039333.

Jeronimo, S. M., Duggal, P., Braz, R. F., Cheng, C., Monteiro, G. R., Nascimento, E. T., Martins, D. R., Karplus, T. M., Ximenes, M. F., Oliveira, C. C., Pinheiro, V. G., Pereira, W., Peralta, J. M., Sousa, J., Medeiros, I. M., Pearsoni, R. D., Burns, T. L., Pugh, E. W. & Wilson, M. E. (2004). An emerging peri-urban pattern of infection with Leishmania chagasi, the protozoan causing visceral leishmaniasis in northeast Brazil. Scand J Infect Dis, 36(6-7), 443-9. PMID: 15307565.

Yao, C., Donelson, J. E. & Wilson, M. E. (2003). The major surface protease (MSP or GP63) of Leishmania sp. Biosynthesis, regulation of expression, and function. Mol Biochem Parasitol, 132(1), 1-16. PMID: 14563532.

Gantt, K. R., Schultz-Cherry, S., Rodriguez, N., Jeronimo, S. M., Nascimento, E. T., Goldman, T. L., Recker, T. J., Miller, M. A. & Wilson, M. E. (2003). Activation of TGF-beta by Leishmania chagasi: importance for parasite survival in macrophages. J Immunol, 170(5), 2613-20. PMID: 12594289.

Karplus, T. M., Jeronimo, S. M., Chang, H., Helms, B. K., Burns, T. L., Murray, J. C., Mitchell, A. A., Pugh, E. W., Braz, R. F., Bezerra, F. L. & Wilson, M. E. (2002). Association between the tumor necrosis factor locus and the clinical outcome of Leishmania chagasi infection. Infect Immun, 70(12), 6919-25. PMID: 12438370.

Wilson, M. E., Recker, T. J., Rodriguez, N. E., Young, B. M., Burnell, K. K., Streit, J. A. & Kline, J. N. (2002). The TGF-beta response to Leishmania chagasi in the absence of IL-12. Eur J Immunol, 32(12), 3556-65. PMID: 12516540.

Braz, R. F., Nascimento, E. T., Martins, D. R., Wilson, M. E., Pearson, R. D., Reed, S. G. & Jeronimo, S. M. (2002). The sensitivity and specificity of Leishmania chagasi recombinant K39 antigen in the diagnosis of American visceral leishmaniasis and in differentiating active from subclinical infection. Am J Trop Med Hyg, 67(4), 344-8. PMID: 12452487.

Myung, K. S., Beetham, J. K., Wilson, M. E. & Donelson, J. E. (2002). Comparison of the post-transcriptional regulation of the mRNAs for the surface proteins PSA (GP46) and MSP (GP63) of Leishmania chagasi. J Biol Chem, 277(19), 16489-97. PMID: 11856749.

Yao, C., Leidal, K. G., Brittingham, A., Tarr, D. E., Donelson, J. E. & Wilson, M. E. (2002). Biosynthesis of the major surface protease GP63 of Leishmania chagasi. Mol Biochem Parasitol, 121(1), 119-28. PMID: 11985868.

Wilson, M. E., Lewis, T. S., Miller, M. A., McCormick, M. L. & Britigan, B. E. (2002). Leishmania chagasi: uptake of iron bound to lactoferrin or transferrin requires an iron reductase. Exp Parasitol, 100(3), 196-207. PMID: 12173405.

Gantt, K. R., Goldman, T. L., McCormick, M. L., Miller, M. A., Jeronimo, S. M., Nascimento, E. T., Britigan, B. E. & Wilson, M. E. (2001). Oxidative responses of human and murine macrophages during phagocytosis of Leishmania chagasi. J Immunol, 167(2), 893-901. PMID: 11441096.

Streit, J. A., Recker, T. J., Filho, F. G., Beverley, S. M. & Wilson, M. E. (2001). Protective immunity against the protozoan Leishmania chagasi is induced by subclinical cutaneous infection with virulent but not avirulent organisms. J Immunol, 166(3), 1921-9. PMID: 11160240.

Brittingham, A., Miller, M. A., Donelson, J. E. & Wilson, M. E. (2001). Regulation of GP63 mRNA stability in promastigotes of virulent and attenuated Leishmania chagasi. Mol Biochem Parasitol, 112(1), 51-9. PMID: 11166386.

Miller, M. A., McGowan, S. E., Gantt, K. R., Champion, M., Novick, S. L., Andersen, K. A., Bacchi, C. J., Yarlett, N., Britigan, B. E. & Wilson, M. E. (2000). Inducible resistance to oxidant stress in the protozoan Leishmania chagasi. J Biol Chem, 275(43), 33883-9. PMID: 10931831.

Gomes, N. A., Gattass, C. R., Barreto-de-Souza, V., Wilson, M. E. & DosReis, G. A. (2000). TGF-beta mediates CTLA-4 suppression of cellular immunity in murine kalaazar. J Immunol, 164(4), 2001-8. PMID: 10657651.

Streit, J. A., Recker, T. J., Donelson, J. E. & Wilson, M. E. (2000). BCG expressing Lcr1 of Leishmania chagasi induces protective immunity in susceptible mice. Exp Parasitol, 94(1), 33-41. PMID: 10631078.

Ximenes, M. F., Castellón, E. G., de Souza, M. F., Freitas, R. A., Pearson, R. D., Wilson, M. E. & Jeronimo, S. M. (2000). Distribution of phlebotomine sand flies (Diptera: Psychodidae) in the state of Rio Grande do Norte, Brazil. J Med Entomol, 37(1), 162-9. PMID: 15218921.

Catmull, J., Wilson, M. E., Kirchhoff, L. V., Metwali, A. & Donelson, J. E. (1999). Induction of specific cell-mediated immunity in mice by oral immunization with Salmonella expressing Onchocerca volvulus glutathione S-transferase. Vaccine, 17(1), 31-9. PMID: 10078605.

Wilson, M. E., Young, B. M., Davidson, B. L., Mente, K. A. & McGowan, S. E. (1998). The importance of TGF-beta in murine visceral leishmaniasis. J Immunol, 161(11), 6148-55. PMID: 9834100.

Gomes, N. A., Barreto-de-Souza, V., Wilson, M. E. & DosReis, G. A. (1998). Unresponsive CD4+ T lymphocytes from Leishmania chagasi-infected mice increase cytokine production and mediate parasite killing after blockade of B7-1/CTLA-4 molecular pathway. J Infect Dis, 178(6), 1847-51. PMID: 9815249.

McCoy, J. J., Beetham, J. K., Ochs, D. E., Donelson, J. E. & Wilson, M. E. (1998). Regulatory sequences and a novel gene in the msp (GP63) gene cluster of Leishmania chagasi. Mol Biochem Parasitol, 95(2), 251-65. PMID: 9803417.

Wilson, M. E., Britigan, B. E. (1998). Iron acquisition by parasitic protozoa. Parasitol Today, 14(9), 348-53. PMID: 17040815.

Wilson, M. E. (1998). Giardiasis. In R. B. Wallace (Eds.) Maxcy-Rosenau-Last public health & preventive medicine. (14th edition) Stamford, CT: Appleton and Lange.

Wilson, M. E., Guerrant, R. L. (1998). Infections Caused by Vibrios. In J. H. Stein (Eds.) Internal Medicine. (5th edition) St. Louis, MO: Mosby.

Wilson, M. E. (1998). Leishmaniasis. In R. B. Wallace (Eds.) Maxcy-Rosenau-Last public health & preventive medicine. (14th edition) Stamford, CT: Appleton and Lange.

Britigan, B. E., Lewis, T. S., McCormick, M. L. & Wilson, M. E. (1998). Evidence for the existence of a surface receptor for ferriclactoferrin and ferrictransferrin associated with the plasma membrane of the protozoan parasite Leishmania donovani. Adv Exp Med Biol, 443, 135-40. PMID: 9781352.

Beetham, J. K., Myung, K. S., McCoy, J. J., Wilson, M. E. & Donelson, J. E. (1997). Glycoprotein 46 mRNA abundance is post-transcriptionally regulated during development of Leishmania chagasi promastigotes to an infectious form. J Biol Chem, 272(28), 17360-6. PMID: 9211875.

McCormick, M. L., Wilson, M. E., Lewis, T. S., Vorhies, R. W. & Britigan, B. E. (1997). Specific binding of ferrilactoferrin and ferritransferrin in the protozoan Leishmania chagasi. In T. W. Hutchens , B. Lonnerdal (Eds.) Lactoferrin: Interactions and Biological Functions. pp. 333-342. Totowa, NJ: Humana Press.

Wilson, M. E., Streit, J. A. (1996). Visceral leishmaniasis. In Parasitic Diseases of the Liver & Intestine. (3), pp. 535-51. Gastroenterol Clin North Am. PMID: 8863039.

Streit, J. A., Donelson, J. E., Agey, M. W. & Wilson, M. E. (1996). Developmental changes in the expression of Leishmania chagasi gp63 and heat shock protein in a human macrophage cell line. Infect Immun, 64(5), 1810-8. PMID: 8613395.

Andersen, K. A., Britigan, B. E. & Wilson, M. E. (1996). Short report: regulation of inducible heat shock protein 70 genes in Leishmania chagasi. Am J Trop Med Hyg, 54(5), 471-4. PMID: 8644900.

Gay, L. S., Wilson, M. E. & Donelson, J. E. (1996). The promoter for the ribosomal RNA genes of Leishmania chagasi. Mol Biochem Parasitol, 77(2), 193-200. PMID: 8813665.

Ramamoorthy, R., Donelson, J. E. & Wilson, M. E. (1996). 5' sequences essential for trans-splicing of msp (gp63) RNAs in Leishmania chagasi. Mol Biochem Parasitol, 77(1), 65-76. PMID: 8784773.

Wilson, M. E., Weinstock, J. V. (1996). Hepatic Granulomas in Murine Visceral Leishmaniasis Caused by Leishmania chagasi. Methods, 9(2), 248-54. PMID: 8812678.

Wilson, M. E., Sandor, M., Blum, A. M., Young, B. M., Metwali, A., Elliott, D., Lynch, R. G. & Weinstock, J. V. (1996). Local suppression of IFN-gamma in hepatic granulomas correlates with tissue-specific replication of Leishmania chagasi. J Immunol, 156(6), 2231-9. PMID: 8690913.

Li, S., Wilson, M. E. & Donelson, J. E. (1996). Leishmania chagasi: a gene encoding a protein kinase with a catalytic domain structurally related to MAP kinase kinase. Exp Parasitol, 82(2), 87-96. PMID: 8617352.

Streit, J. A., Wilson, M. E. (1996). Leishmaniasis. In Current Diagnosis. (Eighth edition) W.B. Saunders, Co..

Ramamoorthy, R., Swihart, K. G., McCoy, J. J., Wilson, M. E. & Donelson, J. E. (1995). Intergenic regions between tandem gp63 genes influence the differential expression of gp63 RNAs in Leishmania chagasi promastigotes. J Biol Chem, 270(20), 12133-9. PMID: 7744862.

Wilson, M. E., Young, B. M., Andersen, K. P., Weinstock, J. V., Metwali, A., Ali, K. M. & Donelson, J. E. (1995). A recombinant Leishmania chagasi antigen that stimulates cellular immune responses in infected mice. Infect Immun, 63(5), 2062-9. PMID: 7729921.

Love, D. C., Wilson, M. E. & Mosser, D. M. (1995). Cloning and characterization of the ribosomal l11 gene from Leishmania spp. Mol Biochem Parasitol, 71(2), 261-4. PMID: 7477109.

Roberts, S. C., Wilson, M. E. & Donelson, J. E. (1995). Developmentally regulated expression of a novel 59-kDa product of the major surface protease (Msp or gp63) gene family of Leishmania chagasi. J Biol Chem, 270(15), 8884-92. PMID: 7721796.

Wilson, M. E., Andersen, K. A. & Britigan, B. E. (1994). Response of Leishmania chagasi promastigotes to oxidant stress. Infect Immun, 62(11), 5133-41. PMID: 7927797.

Cain, C., Stone, M. S., Thieberg, M. & Wilson, M. E. (1994). Nonhealing genital ulcers. Cutaneous leishmaniasis. Arch Dermatol, 130(10), 1313, 1315-6. PMID: 7944519.

Wilson, M. E., Vorhies, R. W., Andersen, K. A. & Britigan, B. E. (1994). Acquisition of iron from transferrin and lactoferrin by the protozoan Leishmania chagasi. Infect Immun, 62(8), 3262-9. PMID: 8039896.

Noben, N. N., Wilson, M. E. & Lynch, R. G. (1994). Modulation of the low-affinity IgE Fc receptor (Fc epsilon RII/CD23) by Leishmania chagasi. Int Immunol, 6(7), 935-45. PMID: 7947462.

Roberts, S. C., Swihart, K. G., Agey, M. W., Ramamoorthy, R., Wilson, M. E. & Donelson, J. E. (1993). Sequence diversity and organization of the msp gene family encoding gp63 of Leishmania chagasi. Mol Biochem Parasitol, 62(2), 157-71. PMID: 8139613.

Wilson, M. E., Paetz, K. E., Ramamoorthy, R. & Donelson, J. E. (1993). The effect of ongoing protein synthesis on the steady state levels of Gp63 RNAs in Leishmania chagasi. J Biol Chem, 268(21), 15731-6. PMID: 8340397.

Wilson, M. E., Guerrant, R. L. (1993). Infections Caused by Vibrios. In J. H. Stein (Eds.) Internal medicine : diagnosis and therapy. (3rd edition) Norwalk, CT: Appleton & Lange.

Wilson, M. E., Guerrant, R. L. (1993). Infections Caused by Vibrios. In J. H. Stein (Eds.) Internal Medicine diagnosis & therapy. (3rd edition) London: Prentice-Hall.

Wilson, M. E. (1993). Leishmaniasis. Curr Opin Infect Dis, 6, 331-41.

Wilson, M. E., Donelson, J. E., Pearson, R. D. & Ramamoorthy, R. (1993). Macrophage Receptors and Leishmania. In T. K. Korhonen , T. Hovi , P. H. Makela (Eds.) Molecular Recognition in Host-Parasite Interactions. Boston, MA: Springer.

Ramamoorthy, R., Donelson, J. E., Paetz, K. E., Maybodi, M., Roberts, S. C. & Wilson, M. E. (1992). Three distinct RNAs for the surface protease gp63 are differentially expressed during development of Leishmania donovani chagasi promastigotes to an infectious form. J Biol Chem, 267(3), 1888-95. PMID: 1370484.

Wilson, M. E. (1992). Giardiasis. In J. M. Last , R. B. Wallace (Eds.) Maxcy-Roseneau-Last Public health & preventive medicine. (13th Edition) Prentice-Hall.

Zarley, J. H., Britigan, B. E. & Wilson, M. E. (1991). Hydrogen peroxide-mediated toxicity for Leishmania donovani chagasi promastigotes. Role of hydroxyl radical and protection by heat shock. J Clin Invest, 88(5), 1511-21. PMID: 1658042.

Kirchhoff, L. V., Wilson, M. E. (1991). Chagas' Disease, African Trypanosomiasis, and Leishmaniasis. Curr Opin Infect Dis, 4, 273-81.

Wilson, M. E., Hardin, K. K. (1990). The major Leishmania donovani chagasi surface glycoprotein in tunicamycin-resistant promastigotes. J Immunol, 144(12), 4825-34. PMID: 2191040.

Wilson, M. E., Pearson, R. D. (1990). Immunology of Leishmaniasis. In D. J. Wyler (Eds.) Modern parasite biology : cellular, immunological, and molecular aspects. New York: W.H. Freeman.

Wilson, M. E. (1990). Leishmaniasis. Curr Opin Infect Dis, 3, 420-6.

Wilson, M. E., Hardin, K. K. & Donelson, J. E. (1989). Expression of the major surface glycoprotein of Leishmania donovani chagasi in virulent and attenuated promastigotes. J Immunol, 143(2), 678-84. PMID: 2738406.

Evans, T. G., Krug, E. C., Wilson, M. E., Vasconcelos, A. W., de Alencar, J. E. & Pearson, R. D. (1989). Evaluation of antibody responses in American visceral leishmaniasis by ELISA and immunoblot. Mem Inst Oswaldo Cruz, 84(2), 157-66. PMID: 2635749.

Pearson, R. D., Wilson, M. E. (1989). Host defenses against prototypical intracellular protozoans, the Leishmania. In P. D. Walzer , R. M. Genta (Eds.) Parasitic Infections in the Compromised Host. New York: Marcel Dekker.

Wilson, M. E., Hardin, K. K. (1988). The major concanavalin A-binding surface glycoprotein of Leishmania donovani chagasi promastigotes is involved in attachment to human macrophages. J Immunol, 141(1), 265-72. PMID: 3379307.

Wilson, M. E., Pearson, R. D. (1988). Roles of CR3 and mannose receptors in the attachment and ingestion of Leishmania donovani by human mononuclear phagocytes. Infect Immun, 56(2), 363-9. PMID: 2962944.

Wilson, M. E., Innes, D. J., Sousa, A. D. & Pearson, R. D. (1987). Early histopathology of experimental infection with Leishmania donovani in hamsters. J Parasitol, 73(1), 55-63. PMID: 3572666.

Wilson, M. E., Guerrant, R. L. (1987). Infections Caused by Vibrios. In J. H. Stein (Eds.) Internal Medicine. (2nd edition) Boston ; Toronto: Little Brown.

Wilson, M. E., Pearson, R. D. (1986). Evidence that Leishmania donovani utilizes a mannose receptor on human mononuclear phagocytes to establish intracellular parasitism. J Immunol, 136(12), 4681-8. PMID: 3711662.

Wilson, M. E., Pearson, R. D. (1986). Parasitic diseases of normal hosts in North America. Hosp Pract (Office ed), 21(4), 164A-164D, 164I-164L, 164P-164Q pas. PMID: 3082907.

Pearson, R. D., Wilson, M. E. (1986). Role of Praziquantel in the Treatment of Helminthic Disease. Intern Med, 7, 183-204.

Wilson, M. E., Pearson, R. D. (1984). Stage-specific variations in lectin binding to Leishmania donovani. Infect Immun, 46(1), 128-34. PMID: 6480103.

Mata, M., Dorovini-Zis, K., Wilson, M. E. & Young, A. B. (1983). New form of familial Parkinson-dementia syndrome: clinical and pathologic findings. Neurology, 33(11), 1439-43. PMID: 6685236.