Prajwal Gurung, PhD
Associate Professor of Internal Medicine-Infectious Diseases
Current Positions
- Associate Professor of Internal Medicine-Infectious Diseases
Education
- PhD, Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa
- Postdoctoral Fellow, Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee
Center, Program and Institute Affiliations
Selected Publications
- Poudel, B., Yorek, M. S., Mazgaeen, L., Brown, S. A., Kanneganti, T. D. & Gurung, P. (2020). Acute IL-4 Governs Pathogenic T Cell Responses during Leishmania major Infection. ImmunoHorizons 4 (9) 546-560. DOI: 10.4049/immunohorizons.2000076. PMID: 32948646.
- Harrington, V. & Gurung, P. (2020). Reconciling protective and pathogenic roles of the NLRP3 inflammasome in leishmaniasis. Immunological reviews. DOI: 10.1111/imr.12886. PMID: 32564424.
- Mazgaeen, L. & Gurung, P. (2020). Neutro"feels" lethal toxin. Journal of leukocyte biology. DOI: 10.1002/JLB.4CE0320-101R. PMID: 32401416.
- Tartey, S., Gurung, P., Karki, R., Burton, A., Hertzog, P. & Kanneganti, T. D. (2020). Ets-2 deletion in myeloid cells attenuates IL-1α-mediated inflammatory disease caused by a Ptpn6 point mutation. Cellular & molecular immunology. DOI: 10.1038/s41423-020-0398-7. PMID: 32203187.
- Dasari, T. K., Geiger, R., Karki, R., Banoth, B., Sharma, B. R., Gurung, P., Burton, A. & Kanneganti, T. D. (2020). The nonreceptor tyrosine kinase SYK drives caspase-8/NLRP3 inflammasome-mediated autoinflammatory osteomyelitis. The Journal of biological chemistry 295 (11) 3394-3400. DOI: 10.1074/jbc.RA119.010623. PMID: 31719149. PMCID: PMC7076204.
- Malireddi, S., Gurung, P., Kesavardhana, S., Samir, P., Burton, A., Mummareddy, H., Vogel, P., Pelletier, S., Burgula, S. & Kanneganti, T. D. (2020). Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease. The Journal of experimental medicine 217 (3). DOI: 10.1084/jem.20191644. PMID: 31869420. PMCID: PMC7062518.
- Mazgaeen, L. & Gurung, P. (2020). Recent Advances in Lipopolysaccharide Recognition Systems. International journal of molecular sciences 21 (2). DOI: 10.3390/ijms21020379. PMID: 31936182. PMCID: PMC7013859.
- Yorek, M. S., Poudel, B., Mazgaeen, L., Pope, R. M., Wilson, M. E. & Gurung, P. (2019). Leishmania major degrades murine CXCL1 - An immune evasion strategy. PLoS neglected tropical diseases 13 (7) e0007533. DOI: 10.1371/journal.pntd.0007533. PMID: 31260451. PMCID: PMC6625741.
- Geesala, R., Schanz, W., Biggs, M., Dixit, G., Skurski, J., Gurung, P., Meyerholz, D. K., Elliott, D., Issuree, P. D. & Maretzky, T. (2019). Loss of RHBDF2 results in an early-onset spontaneous murine colitis. Journal of leukocyte biology 105 (4) 767-781. DOI: 10.1002/JLB.4A0718-283RR. PMID: 30694569. PMCID: PMC6585405.
- Sharma, B. R., Karki, R., Lee, E., Zhu, Q., Gurung, P. & Kanneganti, T. D. (2019). Innate immune adaptor MyD88 deficiency prevents skin inflammation in SHARPIN-deficient mice. Cell death and differentiation 26 (4) 741-750. DOI: 10.1038/s41418-018-0159-7. PMID: 30038386. PMCID: PMC6460383.