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Steven Lentz, MD, PhD

Professor of Internal Medicine-Hematology, Oncology, and Blood and Marrow Transplantation

Current Positions

  • Professor of Internal Medicine-Hematology, Oncology, and Blood & Marrow Transplantation
  • Henry Hamilton Chair in Hematology
  • Director, University of Iowa Medical Scientist Training Program

Education

  • MD, Washington University, St. Louis, Missouri
  • PhD, Molecular Biology, Washington University, St. Louis, Missouri
  • Resident, Internal Medicine, Barnes Hospital, St. Louis, Missouri
  • Fellow, Hematology-Oncology, Washington University, St. Louis, Missouri

Graduate Program Affiliations

Center, Program and Institute Affiliations

Licenses & Certifications

  • Certification, American Board of Internal Medicine
  • Certification, American Board of Internal Medicine, Hematology

Selected Publications

  • Zahr, F. E. & Lentz, S. R. (2016). Von Willebrand Factor–A Rapid Sensor of Paravalvular Regurgitation during TAVR?. The New England Journal of Medicine 375 (4) 382–383. DOI: 10.1056/NEJMe1607326. PMID: 27464206.
  • Lentz, S. R. & and others Nonacog beta pegol (N9-GP) in hemophilia B: a multinational phase 3 safety and efficacy extension trial (paradigm-4).
  • Buckner, T. W., Leavitt, A. D., Ragni, M., Kempton, C. L., Eyster, M. E., Cuker, A., Lentz, S. R., Ducore, J., Leissinger, C., Wang, M. & Key, N. S. (2016). Prospective, multicenter study of postoperative deep-vein thrombosis in patients with haemophilia undergoing major orthopaedic surgery. Thrombosis and Haemostasis 116 (1) 42–49. DOI: 10.1160/TH15-10-0802. PMID: 27009484.
  • Kearon, C., Parpia, S., Spencer, F. A., Baglin, T., Stevens, S. M., Bauer, K. A., Lentz, S. R., Kessler, C. M., Douketis, J. D., Moll, S., Kaatz, S., Schulman, S., Connors, J. M., Ginsberg, J. S., Spadafora, L., Liaw, P. C., Weitz, J. I. & Julian, J. A. (2016). D-dimer levels and recurrence in patients with unprovoked VTE and a negative qualitative D-dimer test after treatment. Thrombosis Research. DOI: 10.1016/j.thromres.2016.06.023. PMID: 27354153.
  • Young, G., Collins, P. W., Colberg, T., Chuansumrit, A., Hanabusa, H., Lentz, S. R., Mahlangu, J., Mauser-Bunschoten, E. P., Négrier, C., Oldenburg, J., Patiroglu, T., Santagostino, E., Tehranchi, R., Zak, M. & Karim, F. A. (2016). Nonacog beta pegol (N9-GP) in haemophilia B: A multinational phase III safety and efficacy extension trial (paradigm™4). Thrombosis Research 141 69–76. DOI: 10.1016/j.thromres.2016.02.030. PMID: 26970716.
  • Flood, V. H., Christopherson, P. A., Gill, J. C., Friedman, K. D., Haberichter, S. L., Bellissimo, D. B., Udani, R. A., Dasgupta, M., Hoffmann, R. G., Ragni, M. V., Shapiro, A. D., Lusher, J. M., Lentz, S. R., Abshire, T. C., Leissinger, C., Hoots, W. K., Manco-Johnson, M. J., Gruppo, R. A., Boggio, L. N., Montgomery, K. T., Goodeve, A. C., James, P. D., Lillicrap, D., Peake, I. R. & Montgomery, R. R. (2016). Clinical and laboratory variability in a cohort of patients diagnosed with type 1 VWD in the United States. Blood 127 (20) 2481–2488. DOI: 10.1182/blood-2015-10-673681. PMID: 26862110.
  • Niki, M., Nayak, M. K., Jin, H., Bhasin, N., Plow, E. F., Pandolfi, P. P., Rothman, P. B., Chauhan, A. K. & Lentz, S. R. (2016). Dok-1 negatively regulates platelet integrin αIIbβ3 outside-in signalling and inhibits thrombosis in mice. Thrombosis and Haemostasis 115 (5) 969–978. DOI: 10.1160/TH15-05-0373. PMID: 26790499.
  • Gu, S. X., Blokhin, I. O., Wilson, K. M., Dhanesha, N., Doddapattar, P., Grumbach, I. M., Chauhan, A. K. & Lentz, S. R. (2016). Protein methionine oxidation augments reperfusion injury in acute ischemic stroke. JCI insight 1 (7). DOI: 10.1172/jci.insight.86460. PMID: 27294204.
  • DeLuca, A. P., Whitmore, S. S., Barnes, J., Sharma, T. P., Westfall, T. A., Scott, C. A., Weed, M. C., Wiley, J. S., Wiley, L. A., Johnston, R. M., Schnieders, M. J., Lentz, S. R., Tucker, B. A., Mullins, R. F., Scheetz, T. E., Stone, E. M. & Slusarski, D. C. (2016). Hypomorphic mutations in TRNT1 cause retinitis pigmentosa with erythrocytic microcytosis. Human Molecular Genetics 25 (1) 44–56. DOI: 10.1093/hmg/ddv446. PMID: 26494905.
  • Dhanesha, N., Ahmad, A., Prakash, P., Doddapattar, P., Lentz, S. R. & Chauhan, A. K. (2015). Genetic Ablation of Extra Domain A of Fibronectin in Hypercholesterolemic Mice Improves Stroke Outcome by Reducing Thrombo-Inflammation. Circulation 132 (23) 2237–2247. DOI: 10.1161/CIRCULATIONAHA.115.016540. PMID: 26508731.