Logo for University of Iowa Health Care This logo represents the University of Iowa Health Care

Recent Research Publications - August 2019

August 16-31, 2019

Platelet antioxidants: A conundrum in aging. Iyer KS, Dayal S. EBioMedicine. 2019 Aug 27. pii: S2352-3964(19)30568-7. doi: 10.1016/j.ebiom.2019.08.046. [Epub ahead of print] No abstract available.  PMID: 31471268 [PubMed - as supplied by publisher]

The prevalence and significance of radiographic incidental findings during initial staging of melanoma: A retrospective study. Stump M, Keller J, Mott SL, Stolmeier D, Milhem M, Liu V. J Eur Acad Dermatol Venereol. 2019 Aug 30. doi: 10.1111/jdv.15912. [Epub ahead of print] PMID: 31469463 [PubMed - as supplied by publisher]

Prolonged postprocedural antimicrobial use: A survey of the Society for Healthcare Epidemiology of America Research Network. Puig-Asensio M, Perencevich EN, Livorsi DJ. Infect Control Hosp Epidemiol. 2019 Aug 30:1-3. doi: 10.1017/ice.2019.242. [Epub ahead of print] PMID: 31466542 [PubMed - as supplied by publisher]

An Investigation of p53 in Skeletal Muscle Aging. Ebert SM, Dierdorff JM, Meyerholz DK, Bullard SA, Al-Zougbi A, DeLau AD, Tomcheck KC, Skopec ZP, Marcotte GR, Bodine SC, Adams CM. J Appl Physiol (1985). 2019 Aug 29. doi: 10.1152/japplphysiol.00363.2019. [Epub ahead of print] PMID: 31465716 [PubMed - as supplied by publisher]

Anxiety, C-reactive protein, and obesity in NHANES 1999-2004. Persons JE, Pierce GL, Fiedorowicz JG. Heliyon. 2019 Aug 17;5(8):e02267. doi: 10.1016/j.heliyon.2019.e02267. eCollection 2019 Aug. PMID: 31463391 [PubMed]

Cardiorespiratory fitness and hippocampal volume predict faster episodic associative learning in older adults. Cole RC, Hazeltine E, Weng TB, Wharff C, DuBose LE, Schmid P, Sigurdsson G, Magnotta VA, Pierce GL, Voss MW. Hippocampus. 2019 Aug 28. doi: 10.1002/hipo.23151. [Epub ahead of print] PMID: 31461198 [PubMed - as supplied by publisher]

Trastuzumab and pertuzumab in circulating tumor DNA ERBB2-amplified HER2-positive refractory cholangiocarcinoma. Yarlagadda B, Kamatham V, Ritter A, Shahjehan F, Kasi PM. NPJ Precis Oncol. 2019 Aug 19;3:19. doi: 10.1038/s41698-019-0091-4. eCollection 2019. PMID: 31453370 [PubMed]

Prediction of short- and long-term mortality in takotsubo syndrome: the InterTAK Prognostic Score. Liu K, et al. Eur J Heart Fail. 2019 Aug 27. doi: 10.1002/ejhf.1561. [Epub ahead of print] No abstract available.  PMID: 31452320 [PubMed - as supplied by publisher]

Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium. Liu G, Thangavel R, Rysted J, Kim Y, Francis MB, Adams E, Lin Z, Taugher RJ, Wemmie JA, Usachev YM, Lee G. J Neurosci Res. 2019 Aug 26. doi: 10.1002/jnr.24517. [Epub ahead of print] PMID: 31452242 [PubMed - as supplied by publisher]

Acid-Sensing Ion Channels: Novel Mediators of Cerebral Vascular Responses. Faraci FM, Taugher RJ, Lynch CM, Fan R, Gupta S, Wemmie J. Circ Res. 2019 Aug 27. doi: 10.1161/CIRCRESAHA.119.315024. [Epub ahead of print] PMID: 31451088 [PubMed - as supplied by publisher]

The impact of safety-net burden on in-hospital outcomes after surgical aortic valve replacement. Ando T, Adegbala O, Akintoye E, Briasoulis A, Takagi H. J Card Surg. 2019 Aug 23. doi: 10.1111/jocs.14187. [Epub ahead of print] PMID: 31441545 [PubMed - as supplied by publisher]

Radiographic Lung Volumes Predict Progression to COPD in Smokers with Preserved Spirometry in SPIROMICS. Arjomandi M, Zeng S, Barjaktarevic I, Barr RG, Bleecker ER, Bowler RP, Buhr RG, Criner GJ, Comellas AP, Cooper CB, Couper DJ, Curtis JL, Dransfield MT, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Kanner RE, Krishnan JA, Paine R 3rd, Peters SP, Rennard SI, Woodruff PG; SPIROMICS Investigators. Eur Respir J. 2019 Aug 22. pii: 1802214. doi: 10.1183/13993003.02214-2018. [Epub ahead of print] PMID: 31439683 [PubMed - as supplied by publisher]

An On-Treatment Analysis of the MARQUIS Study: Interventions to Improve Inpatient Medication Reconciliation. Mixon AS, Kripalani S, Stein J, Wetterneck TB, Kaboli P, Mueller S, Burdick E, Nolido NV, Labonville S, Minahan JA, Orav EJ, Goldstein J, Schnipper JL. J Hosp Med. 2019 Aug 16;14. doi: 10.12788/jhm.3308. [Epub ahead of print] PMID: 31433768 [PubMed - as supplied by publisher]

Perspectives of United States-based Infectious Diseases Physicians on Outpatient Parenteral Antimicrobial Therapy Practice. Hamad Y, Lane MA, Beekmann SE, Polgreen PM, Keller SC. Open Forum Infect Dis. 2019 Aug 20. pii: ofz363. doi: 10.1093/ofid/ofz363. [Epub ahead of print] PMID: 31429872 [PubMed - as supplied by publisher]

First-in-human phase 1 clinical trial of pharmacological ascorbate combined with radiation and temozolomide for newly diagnosed glioblastoma. Bodeker KL, Allen BG, Smith MC, Monga V, Sandhu S, Hohl RJ, Carlisle TL, Brown HA, Hollenbeck NJ, Vollstedt S, Greenlee JDW, Howard MA, Mapuskar KA, Seyedin SN, Caster JM, Jones KA, Cullen JJ, Berg DJ, Wagner BA, Buettner GR, TenNapel MJ, Smith BJ, Spitz DR, Buatti JM. Clin Cancer Res. 2019 Aug 19. pii: clincanres.0594.2019. doi: 10.1158/1078-0432.CCR-19-0594. [Epub ahead of print] PMID: 31427282 [PubMed - as supplied by publisher]

Ferroportin downregulation promotes cell proliferation by modulating the Nrf2-miR-17-5p axis in multiple myeloma. Kong Y, Hu L, Lu K, Wang Y, Xie Y, Gao L, Yang G, Xie B, He W, Chen G, Wu H, Wu X, Zhan F, Shi J. Cell Death Dis. 2019 Aug 19;10(9):624. doi: 10.1038/s41419-019-1854-0. PMID: 31423010 [PubMed - in process]

Smooth Muscle Cell-Specific Disruption of the BBSome Causes Vascular Dysfunction. Reho JJ, Guo DF, Morgan DA, Rahmouni K. Hypertension. 2019 Aug 19:HYPERTENSIONAHA11913382. doi: 10.1161/HYPERTENSIONAHA.119.13382. [Epub ahead of print] PMID: 31422694 [PubMed - as supplied by publisher]

Performance of Administrative Algorithms to Identify Interstitial Lung Disease in Rheumatoid Arthritis. England BR, Roul P, Mahajan TD, Singh N, Yu F, Sayles H, Cannon GW, Sauer BC, Baker JF, Curtis JR, Mikuls TR. Arthritis Care Res (Hoboken). 2019 Aug 17. doi: 10.1002/acr.24043. [Epub ahead of print] PMID: 31421018 [PubMed - as supplied by publisher]

Nursing roles for in-hospital cardiac arrest response: higher versus lower performing hospitals. Guetterman TC, Kellenberg JE, Krein SL, Harrod M, Lehrich JL, Iwashyna TJ, Kronick SL, Girotra S, Chan PS, Nallamothu BK. BMJ Qual Saf. 2019 Aug 16. pii: bmjqs-2019-009487. doi: 10.1136/bmjqs-2019-009487. [Epub ahead of print] PMID: 31420410 [PubMed - as supplied by publisher]

Radiomic measures from chest high-resolution computed tomography associated with lung function in sarcoidosis. Ryan SM, Fingerlin TE, Mroz M, Barkes B, Hamzeh N, Maier LA, Carlson NE. Eur Respir J. 2019 Aug 29;54(2). pii: 1900371. doi: 10.1183/13993003.00371-2019. Print 2019 Aug. PMID: 31196947 [PubMed - in process]

Exploring the Relationship Between Patient Activation, Treatment Satisfaction, and Decisional Conflict in Patients Approaching End-Stage Renal Disease. Vélez-Bermúdez M, Christensen AJ, Kinner EM, Roche AI, Fraer M. Ann Behav Med. 2019 Aug 16;53(9):816-826. doi: 10.1093/abm/kay091. PMID: 30535065 [PubMed - in process]

August 1-15, 2019

Quorum Sensing, Virulence, and Antibiotic Resistance of USA100 Methicillin-Resistant Staphylococcus aureus Isolates. Grundstad ML, Parlet CP, Kwiecinski JM, Kavanaugh JS, Crosby HA, Cho YS, Heilmann K, Diekema DJ, Horswill AR. mSphere. 2019 Aug 14;4(4). pii: e00553-19. doi: 10.1128/mSphere.00553-19. PMID: 31413175 [PubMed - in process]

p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas. Hsieh MH, Choe JH, Gadhvi J, Kim YJ, Arguez MA, Palmer M, Gerold H, Nowak C, Do H, Mazambani S, Knighton JK, Cha M, Goodwin J, Kang MK, Jeong JY, Lee SY, Faubert B, Xuan Z, Abel ED, Scafoglio C, Shackelford DB, Minna JD, Singh PK, Shulaev V, Bleris L, Hoyt K, Kim J, Inoue M, DeBerardinis RJ, Kim TH, Kim JW. Cell Rep. 2019 Aug 13;28(7):1860-1878.e9. doi: 10.1016/j.celrep.2019.07.027. PMID: 31412252 [PubMed - in process]

Assessment of Patient Nondisclosures to Clinicians of Experiencing Imminent Threats. Levy AG, Scherer AM, Zikmund-Fisher BJ, Larkin K, Barnes GD, Fagerlin A. JAMA Netw Open. 2019 Aug 2;2(8):e199277. doi: 10.1001/jamanetworkopen.2019.9277. PMID: 31411716 [PubMed - in process]

Attitudes of Clinicians about Screening Head and Neck Cancer Survivors for Lung Cancer Using Low-Dose Computed Tomography. Dukes K, Seaman AT, Hoffman RM, Christensen AJ, Kendell N, Sussman AL, Vélez-Bermúdez M, Volk RJ, Pagedar NA. Ann Otol Rhinol Laryngol. 2019 Aug 13:3489419868245. doi: 10.1177/0003489419868245. [Epub ahead of print] PMID: 31409114 [PubMed - as supplied by publisher]

Identification and Characterization of Tumor-Initiating Cells in Multiple Myeloma. Gao M, Bai H, Jethava Y, Wu Y, Zhu Y, Yang Y, Xia J, Cao H, Franqui-Machin R, Nadiminti K, Thomas GS, Salama ME, Altevogt P, Bishop G, Tomasson M, Janz S, Shi J, Chen L, Frech I, Tricot G, Zhan F. J Natl Cancer Inst. 2019 Aug 12. pii: djz159. doi: 10.1093/jnci/djz159. [Epub ahead of print] PMID: 31406992 [PubMed - as supplied by publisher]

iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition. Chen S, Wu J, Zhong S, Li Y, Zhang P, Ma J, Ren J, Tan Y, Wang Y, Au KF, Siebold C, Bond GL, Chen Z, Lu M, Jones EY, Lu X. Proc Natl Acad Sci U S A. 2019 Aug 8. pii: 201909393. doi: 10.1073/pnas.1909393116. [Epub ahead of print] PMID: 31395738 [PubMed - as supplied by publisher]

Validation of Microsatellite Instability Detection Using a Comprehensive Plasma-Based Genotyping Panel. Willis J, Lefterova MI, Artyomenko A, Kasi PM, Nakamura Y, Mody K, Catenacci DVT, Fakih M, Barbacioru C, Zhao J, Sikora M, Fairclough SR, Lee H, Kim KM, Kim ST, Kim J, Gavino D, Benavides M, Peled N, Nguyen T, Cusnir M, Eskander RN, Azzi G, Yoshino T, Banks KC, Raymond VM, Lanman RB, Chudova DI, Talasaz A, Kopetz S, Lee J, Odegaard JI. Clin Cancer Res. 2019 Aug 4. doi: 10.1158/1078-0432.CCR-19-1324. [Epub ahead of print] PMID: 31383735 [PubMed - as supplied by publisher]

Antecedent Carbapenem Exposure as a Risk Factor for Non-Carbapenemase-Producing Carbapenem-Resistant Enterobacteriaceae (NCPCRE) and Carbapenemase-Producing Enterobacteriaceae (CPE). Marimuthu K, Ng OT, Cherng BPZ, Fong RKC, Pada SK, De PP, Ooi ST, Smitasin N, Thoon KC, Krishnan PU, Ang M, Chan DSG, Kwa ALH, Deepak RN, Chan YK, Chan YFZ, Huan X, Linn KZ, Tee NWS, Tan TY, Koh TH, Lin RTP, Hsu LY, Sengupta S, Paterson DL, Perencevich E, Harbarth S, Teo J, Venkatachalam I; CaPES study group. Antimicrob Agents Chemother. 2019 Aug 5. pii: AAC.00845-19. doi: 10.1128/AAC.00845-19. [Epub ahead of print] PMID: 31383670 [PubMed - as supplied by publisher]

An RNA aptamer-based biomarker platform demonstrates high soluble CD25 occupancy by IL2 in the serum of follicular lymphoma patients. Veeramani S, Blackwell SE, Thiel WH, Yang ZZ, Ansell SM, Giangrande PH, Weiner GJ. Cancer Immunol Res. 2019 Aug 5. pii: canimm.0821.2018. doi: 10.1158/2326-6066.CIR-18-0821. [Epub ahead of print] PMID: 31383650 [PubMed - as supplied by publisher]

High-energy external defibrillation and transcutaneous pacing during MRI: feasibility and safety. Shusterman V, Hodgson-Zingman D, Thedens D, Zhu X, Hoffman S, Sieren JC, Morgan GM, Faranesh A, London B. J Cardiovasc Magn Reson. 2019 Aug 5;21(1):47. doi: 10.1186/s12968-019-0558-z. PMID: 31378203 [PubMed - in process] Free PMC Article

Mediation of Adverse Pregnancy Outcomes in Autoimmune Conditions by Pregnancy Complications. Bandoli G, Singh N, Strouse J, Baer RJ, Donovan BM, Feuer SK, Nidey N, Ryckman KK, Jelliffe-Pawlowski LL, Chambers CD. Arthritis Care Res (Hoboken). 2019 Aug 2. doi: 10.1002/acr.24037. [Epub ahead of print] PMID: 31373768 [PubMed - as supplied by publisher]

Novel functions of inactive rhomboid proteins in immunity and disease. Geesala R, Issuree PD, Maretzky T. J Leukoc Biol. 2019 Aug 1. doi: 10.1002/JLB.3VMR0219-069R. [Epub ahead of print] Review. PMID: 31369701 [PubMed - as supplied by publisher]

Modulation of complex II-energized respiration in muscle, heart, and brown adipose mitochondria by oxaloacetate and complex I electron flow. Fink BD, Yu L, Sivitz WI. FASEB J. 2019 Aug 1:fj201900690R. doi: 10.1096/fj.201900690R. [Epub ahead of print] PMID: 31361970 [PubMed - as supplied by publisher]

ULK2 is essential for degradation of ubiquitinated protein aggregates and homeostasis in skeletal muscle. Fuqua JD, Mere CP, Kronemberger A, Blomme J, Bae D, Turner KD, Harris MP, Scudese E, Edwards M, Ebert SM, de Sousa LGO, Bodine SC, Yang L, Adams CM, Lira VA. FASEB J. 2019 Aug 9:fj201900766R. doi: 10.1096/fj.201900766R. [Epub ahead of print] PMID: 31361156 [PubMed - as supplied by publisher]

ACG Clinical Guideline: Hereditary Hemochromatosis. Kowdley KV, Brown KE, Ahn J, Sundaram V. Am J Gastroenterol. 2019 Aug;114(8):1202-1218. doi: 10.14309/ajg.0000000000000315. PMID: 31335359 [PubMed - in process]

Response by Holwerda et al to Letter Regarding Article "Elevated Muscle Sympathetic Nerve Activity Contributes to Central Artery Stiffness in Young and Middle-Age/Older Adults". Holwerda SW, Fadel PJ, Abboud FM, Pierce GL. Hypertension. 2019 Aug;74(2):e33. doi: 10.1161/HYPERTENSIONAHA.119.13299. Epub 2019 Jun 24. No abstract available.  PMID: 31230540 [PubMed - in process]

Critical Roles for Coiled-Coil Dimers of Butyrophilin 3A1 in the Sensing of Prenyl Pyrophosphates by Human Vγ2Vδ2 T Cells. Wang H, Nada MH, Tanaka Y, Sakuraba S, Morita CT. J Immunol. 2019 Aug 1;203(3):607-626. doi: 10.4049/jimmunol.1801252. Epub 2019 Jun 21. PMID: 31227581 [PubMed - in process]

In-Hospital Outcomes of ST-Segment Elevation Myocardial Infarction Complicated With Cardiogenic Shock at Safety-Net Hospitals in the United States (from the Nationwide Inpatient Sample). Ando T, Akintoye E, Adegbala O, Ashraf S, Shokr M, Takagi H, Grines CL, Afonso L, Briasoulis A. Am J Cardiol. 2019 Aug 15;124(4):485-490. doi: 10.1016/j.amjcard.2019.05.037. Epub 2019 May 28. PMID: 31213279 [PubMed - in process]

Role of diabetes and insulin use in the risk of stroke and acute myocardial infarction in patients with atrial fibrillation: A Medicare analysis. Mentias A, Shantha G, Adeola O, Barnes GD, Narasimhan B, Siontis KC, Levine DA, Sah R, Giudici MC, Vaughan Sarrazin M. Am Heart J. 2019 Aug;214:158-166. doi: 10.1016/j.ahj.2019.05.003. Epub 2019 May 10. PMID: 31212115 [PubMed - in process]

Single-molecule long-read sequencing reveals the chromatin basis of gene expression. Wang Y, Wang A, Liu Z, Thurman AL, Powers LS, Zou M, Zhao Y, Hefel A, Li Y, Zabner J, Au KF. Genome Res. 2019 Aug;29(8):1329-1342. doi: 10.1101/gr.251116.119. Epub 2019 Jun 14. PMID: 31201211 [PubMed - in process]

The BBSome in POMC and AgRP Neurons Is Necessary for Body Weight Regulation and Sorting of Metabolic Receptors. Guo DF, Lin Z, Wu Y, Searby C, Thedens DR, Richerson GB, Usachev YM, Grobe JL, Sheffield VC, Rahmouni K. Diabetes. 2019 Aug;68(8):1591-1603. doi: 10.2337/db18-1088. Epub 2019 May 24. PMID: 31127052 [PubMed - in process]

Soluble klotho regulates TRPC6 calcium signaling <i>via</i> lipid rafts, independent of the FGFR-FGF23 pathway. Wright JD, An SW, Xie J, Lim C, Huang CL. FASEB J. 2019 Aug;33(8):9182-9193. doi: 10.1096/fj.201900321R. Epub 2019 May 7. PMID: 31063704 [PubMed - in process]

Stress-Induced Sensitization of Angiotensin II Hypertension Is Reversed by Blockade of Angiotensin-Converting Enzyme or Tumor Necrosis Factor-α. Xue B, Yu Y, Wei SG, Beltz TG, Guo F, Felder RB, Johnson AK. Am J Hypertens. 2019 Aug 14;32(9):909-917. doi: 10.1093/ajh/hpz075. PMID: 31063551 [PubMed - in process]

The Pancreas as a Site of Metastasis or Second Primary in Patients with Small Bowel Neuroendocrine Tumors. Scott AT, Pelletier D, Maxwell JE, Sherman SK, Keck KJ, Li G, Dillon JS, O'Dorisio TM, Bellizzi AM, Howe JR. Ann Surg Oncol. 2019 Aug;26(8):2525-2532. doi: 10.1245/s10434-019-07370-3. Epub 2019 Apr 22. PMID: 31011904 [PubMed - in process]

Decreasing frequency and improved outcomes of hepatitis C-related liver transplantation in the era of direct-acting antivirals - a retrospective cohort study. Arora SS, Axley P, Ahmed Z, Satapathy SK, Wong R, Kuo YF, Singal AK. Transpl Int. 2019 Aug;32(8):854-864. doi: 10.1111/tri.13424. Epub 2019 Mar 26. PMID: 30866110 [PubMed - in process]

Incidence trends for upper aerodigestive tract cancers in rural United States counties. Pagedar NA, Kahl AR, Tasche KK, Seaman AT, Christensen AJ, Howren MB, Charlton ME. Head Neck. 2019 Aug;41(8):2619-2624. doi: 10.1002/hed.25736. Epub 2019 Mar 7. PMID: 30843640 [PubMed - in process]

Long-Term Safety Experience with Telotristat Ethyl Across Five Clinical Studies in Patients with Carcinoid Syndrome. Anthony LB, Kulke MH, Caplin ME, Bergsland E, Öberg K, Pavel M, Hörsch D, Warner RRP, O'Dorisio TM, Dillon JS, Lapuerta P, Kassler-Taub K, Jiang W. Oncologist. 2019 Aug;24(8):e662-e670. doi: 10.1634/theoncologist.2018-0236. Epub 2019 Jan 16. PMID: 30651397 [PubMed - in process]

Bare below the elbows in an academic medical center. Godbout EJ, Masroor N, Doll M, Edmond MB, Bearman G, Stevens MP. Am J Infect Control. 2019 Aug;47(8):1030-1031. doi: 10.1016/j.ajic.2018.12.007. Epub 2019 Jan 10. PMID: 30638675 [PubMed - in process]