Recent Research Publications - February 2019

February 16-28, 2019

Once-weekly prophylaxis with glycoPEGylated recombinant factor VIII (N8-GP) in severe haemophilia A: Safety and efficacy results from pathfinder 2 (randomized phase III trial). Curry N, Albayrak C, Escobar M, Andre Holme P, Kearney S, Klamroth R, Misgav M, Négrier C, Wheeler A, Santagostino E, Shima M, Landorph A, Tønder SM, Lentz SR. Haemophilia. 2019 Feb 28. doi: 10.1111/hae.13712. [Epub ahead of print] PMID: 30817066 [PubMed - as supplied by publisher]

Calpain-2 promotes MKP-1 expression protecting cardiomyocytes in both in vitro and in vivo mouse models of doxorubicin-induced cardiotoxicity. Zheng D, Su Z, Zhang Y, Ni R, Fan GC, Robbins J, Song LS, Li J, Peng T. Arch Toxicol. 2019 Feb 27. doi: 10.1007/s00204-019-02405-w. [Epub ahead of print] PMID: 30810770 [PubMed - as supplied by publisher]

Variation in Use of Procurement Biopsies and Its Implications for Discard of Deceased Donor Kidneys Recovered for Transplant. Lentine KL, Naik AS, Schnitzler MA, Randall H, Wellen JR, Kasiske BL, Marklin G, Brockmeier D, Cooper M, Xiao H, Zhang Z, Gaston RS, Rothweiler R, Axelrod DA. Am J Transplant. 2019 Feb 26. doi: 10.1111/ajt.15325. [Epub ahead of print] PMID: 30809941 [PubMed - as supplied by publisher]

Automated insulin dosing guidance to optimise insulin management in patients with type 2 diabetes: a multicentre, randomised controlled trial. Bergenstal RM, Johnson M, Passi R, Bhargava A, Young N, Kruger DF, Bashan E, Bisgaier SG, Isaman DJM, Hodish I. Lancet. 2019 Feb 22. pii: S0140-6736(19)30368-X. doi: 10.1016/S0140-6736(19)30368-X. [Epub ahead of print] PMID: 30808512 [PubMed - as supplied by publisher]

Regional and Rural-Urban Differences in the Use of Direct-acting Antiviral Agents for Hepatitis C Virus: The Veteran Birth Cohort. Njei B, Esserman D, Krishnan S, Ohl M, Tate JP, Hauser RG, Taddei T, Lim J, Justice AC. Med Care. 2019 Feb 22. doi: 10.1097/MLR.0000000000001071. [Epub ahead of print] PMID: 30807449 [PubMed - as supplied by publisher]

Angiotensin II-induced Hypertension and Cardiac Hypertrophy are Differentially Mediated by TLR3- and TLR4-Dependent Pathways. Singh MV, Cicha MZ, Nunez S, Meyerholz DK, Chapleau MW, Abboud FM. Am J Physiol Heart Circ Physiol. 2019 Feb 22. doi: 10.1152/ajpheart.00697.2018. [Epub ahead of print] PMID: 30793936 [PubMed - as supplied by publisher]

Synthesis and Immunomodulatory Activity of Fluorine-Containing Bisphosphonates. Mizuta S, Tagod MSO, Iwasaki M, Nakamura Y, Senju H, Mukae H, Morita CT, Tanaka Y. ChemMedChem. 2019 Feb 19;14(4):462-468. doi: 10.1002/cmdc.201800764. Epub 2019 Jan 25. PMID: 30637982 [PubMed - in process]

February 1-15, 2019

Regulation of cardiac transcription by thyroid hormone and Med13. Minerath RA, Dewey CM, Hall DD, Grueter CE.  J Mol Cell Cardiol. 2019 Feb 12. pii: S0022-2828(18)30833-2. doi: 10.1016/j.yjmcc.2019.01.007. [Epub ahead of print] PMID: 30769017 [PubMed - as supplied by publisher]

Healthcare provider diagnostic testing practices for identification of Clostridioides (Clostridium) difficile in children: an Emerging Infections Network survey. Kociolek LK, Kutty PK, Polgreen PM, Beekmann SE. Infect Control Hosp Epidemiol. 2019 Feb 15:1-5. doi: 10.1017/ice.2018.347. [Epub ahead of print] PMID: 30767829 [PubMed - as supplied by publisher]

Glucose Metabolism is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes Mellitus. Fidler TP, Marti A, Gerth K, Middleton EA, Campbell RA, Rondina MT, Weyrich AS, Abel ED. Diabetes. 2019 Feb 14. pii: db180981. doi: 10.2337/db18-0981. [Epub ahead of print] PMID: 30765335 [PubMed - as supplied by publisher]

Ventilatory response to CO<sub>2</sub> in patients with epilepsy. Sainju RK, Dragon DN, Winnike HB, Nashelsky MB, Granner MA, Gehlbach BK, Richerson GB. Epilepsia. 2019 Feb 12. doi: 10.1111/epi.14660. [Epub ahead of print] PMID: 30756391 [PubMed - as supplied by publisher]

Low-dose apatinib optimizes tumor microenvironment and potentiates antitumor effect of PD-1/PD-L1 blockade in lung cancer. Zhao S, Ren S, Jiang T, Zhu B, Li X, Zhao C, Jia Y, Shi J, Zhang L, Liu X, Qiao M, Chen X, Su C, Yu H, Zhou C, Zhang J, Camidge DR, Hirsch FR. Cancer Immunol Res. 2019 Feb 12. pii: canimm.0640.2017. doi: 10.1158/2326-6066.CIR-17-0640. [Epub ahead of print] PMID: 30755403 [PubMed - as supplied by publisher]

Review of Two Popular Eating Plans within the Multiple Sclerosis Community: Low Saturated Fat and Modified Paleolithic. Wahls TL, Chenard CA, Snetselaar LG. Nutrients. 2019 Feb 7;11(2). pii: E352. doi: 10.3390/nu11020352. Review. PMID: 30736445 [PubMed - in process] Free Article

Attenuation of Sepsis-Induced Cardiomyopathy by Regulation of MicroRNA-23b Is Mediated Through Targeting of MyD88-Mediated NF-κB Activation. Cao C, Zhang Y, Chai Y, Wang L, Yin C, Shou S, Jin H. Inflammation. 2019 Feb 8. doi: 10.1007/s10753-019-00958-7. [Epub ahead of print] PMID: 30734878 [PubMed - as supplied by publisher]

EDA fibronectin-TLR4 axis sustains megakaryocyte expansion and inflammation in bone marrow fibrosis. Malara A, Gruppi C, Abbonante V, Cattaneo D, De Marco L, Massa M, Iurlo A, Gianelli U, Balduini CL, Tira ME, Muro AF, Chauhan AK, Rosti V, Barosi G, Balduini A. J Exp Med. 2019 Feb 7. pii: jem.20181074. doi: 10.1084/jem.20181074. [Epub ahead of print] PMID: 30733282 [PubMed - as supplied by publisher]

Association of Insulin Dose, Cardiometabolic Risk Factors, and Cardiovascular Disease in Type 1 Diabetes During 30 Years of Follow-up in the DCCT/EDIC Study. Braffett BH, Dagogo-Jack S, Bebu I, Sivitz WI, Larkin M, Kolterman O, Lachin JM; DCCT/EDIC Research Group. Diabetes Care. 2019 Feb 6. pii: dc181574. doi: 10.2337/dc18-1574. [Epub ahead of print] PMID: 30728218 [PubMed - as supplied by publisher]

Single-cell profiling of cutaneous T-cell lymphoma reveals underlying heterogeneity associated with disease progression. Borcherding N, Voigt AP, Liu V, Link BK, Zhang W, Jabbari A. Clin Cancer Res. 2019 Feb 4. pii: clincanres.3309.2018. doi: 10.1158/1078-0432.CCR-18-3309. [Epub ahead of print] PMID: 30718356 [PubMed - as supplied by publisher]

A comparative evaluation of hybrid error correction methods for error-prone long reads. Fu S, Wang A, Au KF. Genome Biol. 2019 Feb 4;20(1):26. doi: 10.1186/s13059-018-1605-z. PMID: 30717772 [PubMed - in process] Free PMC Article

Confidence in Women's Health: A Cross Border Survey of Adult Nephrologists. Hendren EM, Reynolds ML, Mariani LH, Zee J, O'Shaughnessy MM, Oliverio AL, Moore NW, Hill-Callahan P, Rizk DV, Almanni S, Twombley KE, Herreshoff E, Nester CM, Hladunewich MA. J Clin Med. 2019 Feb 3;8(2). pii: E176. doi: 10.3390/jcm8020176. PMID: 30717445 [PubMed] Free Article

Cardiac Sodium-Glucose Co-Transporter 1 (SGLT1) is a Novel Mediator of Ischemia/Reperfusion Injury. Li Z, Agrawal V, Ramratnam M, Sharma RK, D'Auria S, Sincoular A, Jakubiak M, Music ML, Kutschke WJ, Huang XN, Gifford L, Ahmad F. Cardiovasc Res. 2019 Feb 4. doi: 10.1093/cvr/cvz037. [Epub ahead of print] PMID: 30715251 [PubMed - as supplied by publisher]

HSP90 inhibitor geldanamycin reverts IL-13- and IL-17-induced airway goblet cell metaplasia. Pezzulo AA, Tudas RA, Stewart CG, Buonfiglio LGV, Lindsay BD, Taft PJ, Gansemer ND, Zabner J. J Clin Invest. 2019 Feb 1;129(2):744-758. doi: 10.1172/JCI123524. Epub 2019 Jan 14. PMID: 30640172 [PubMed - in process] Free Article

Infectious Complications of Conventional Laparoscopic vs Robotic Laparoscopic Prostatectomy: A Systematic Literature Review and Meta-Analysis. Marra AR, Puig-Asensio M, Edmond MB, Schweizer ML, Nepple KG. J Endourol. 2019 Feb 8. doi: 10.1089/end.2018.0815. [Epub ahead of print] PMID: 30632396 [PubMed - as supplied by publisher]

Natural history of Takotsubo syndrome - Arrhythmogenic dilemma. Williford NN, Gebska MA. Int J Cardiol. 2019 Feb 1;276:41. doi: 10.1016/j.ijcard.2018.11.014. No abstract available.  PMID: 30616920 [PubMed - in process]

Symptom Burden Among Community-Dwelling Older Adults in the United States. Patel KV, Guralnik JM, Phelan EA, Gell NM, Wallace RB, Sullivan MD, Turk DC. J Am Geriatr Soc. 2019 Feb;67(2):223-231. doi: 10.1111/jgs.15673. Epub 2018 Dec 12. PMID: 30548453 [PubMed - in process]

A Systematic Review and Meta-analysis of the Association Between Vitamin K Antagonist Use and Fracture. Fiordellisi W, White K, Schweizer M. J Gen Intern Med. 2019 Feb;34(2):304-311. doi: 10.1007/s11606-018-4758-2. Epub 2018 Dec 3. PMID: 30511289 [PubMed - in process]

Disruption of cardiac Med1 inhibits RNA polymerase II promoter occupancy and promotes chromatin remodeling. Hall DD, Spitler KM, Grueter CE. Am J Physiol Heart Circ Physiol. 2019 Feb 1;316(2):H314-H325. doi: 10.1152/ajpheart.00580.2018. Epub 2018 Nov 21. PMID: 30461303 [PubMed - in process]

Outcomes comparison in patients admitted to low complexity rural and urban intensive care units in the Veterans Health Administration. O'Shea AMJ, Fortis S, Vaughan Sarrazin M, Moeckli J, Yarbrough WC, Schacht Reisinger H. J Crit Care. 2019 Feb;49:64-69. doi: 10.1016/j.jcrc.2018.10.013. Epub 2018 Oct 19. PMID: 30388490 [PubMed - in process]