March 16-31, 2020

A Retrospective Analysis of Clinical Trial Accrual of Patients Presented in a Multidisciplinary Tumor Board at a Tertiary Health Care Center and Associated Barriers. Mobley EM, Swami U, Mott S, Ounda A, Milhem M, Monga V. Oncol Res Treat. 2020 Mar 27:1-6. doi: 10.1159/000506840. [Epub ahead of print] PMID: 32222709 [PubMed - as supplied by publisher]

Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling. Riehle C, Weatherford ET, Wende AR, Jaishy BP, Seei AW, McCarty NS, Rech M, Shi Q, Reddy GR, Kutschke WJ, Oliveira K, Pires KM, Anderson JC, Diakos NA, Weiss RM, White MF, Drakos SG, Xiang YK, Abel ED. JCI Insight. 2020 Mar 26;5(6). pii: 134920. doi: 10.1172/jci.insight.134920. PMID: 32213702 [PubMed - in process] 

A Modified MCT-Based Ketogenic Diet Increases Plasma β-Hydroxybutyrate but Has Less Effect on Fatigue and Quality of Life in People with Multiple Sclerosis Compared to a Modified Paleolithic Diet: A Waitlist-Controlled, Randomized Pilot Study. Lee JE, Titcomb TJ, Bisht B, Rubenstein LM, Louison R, Wahls TL. J Am Coll Nutr. 2020 Mar 26:1-13. doi: 10.1080/07315724.2020.1734988. [Epub ahead of print] PMID: 32213121 [PubMed - as supplied by publisher]

Modulation of the cardiac sodium channel Na_V1.5 peak and late currents by NAD⁺ precursors. Matasic DS, Yoon JY, McLendon JM, Mehdi H, Schmidt MS, Greiner AM, Quinones P, Morgan GM, Boudreau RL, Irani K, Brenner C, London B. J Mol Cell Cardiol. 2020 Mar 21. pii: S0022-2828(20)30073-0. doi: 10.1016/j.yjmcc.2020.01.013. [Epub ahead of print] PMID: 32209328 [PubMed - as supplied by publisher]

Infection, Antibiotics, and Patient Outcomes in the Intensive Care Unit. Yin M, Tambyah PA, Perencevich EN. JAMA. 2020 Mar 24. doi: 10.1001/jama.2020.2241. [Epub ahead of print] No abstract available.  PMID: 32207775 [PubMed - as supplied by publisher]

A Typology of New Long-term Opioid Prescribing in the Veterans Health Administration. Hadlandsmyth K, Mosher HJ, Bayman EO, Wikle JG, Lund BC. J Gen Intern Med. 2020 Mar 23. doi: 10.1007/s11606-020-05749-7. [Epub ahead of print] PMID: 32206994 [PubMed - as supplied by publisher]

Review of the first comprehensive outpatient parenteral antimicrobial therapy program in a tertiary care hospital in Japan. Hase R, Yokoyama Y, Suzuki H, Uno S, Mikawa T, Suzuki D, Muranaka K, Hosokawa N. Int J Infect Dis. 2020 Mar 20. pii: S1201-9712(20)30165-X. doi: 10.1016/j.ijid.2020.03.033. [Epub ahead of print] PMID: 32205285 [PubMed - as supplied by publisher]

Initial experience from a renal genetics clinic demonstrates a distinct role in patient management. Thomas CP, Freese ME, Ounda A, Jetton JG, Holida M, Noureddine L, Smith RJ. Genet Med. 2020 Mar 17. doi: 10.1038/s41436-020-0772-y. [Epub ahead of print] PMID: 32203225 [PubMed - as supplied by publisher]

Variability in the Management of Adults with Pulmonary Nontuberculous Mycobacterial Disease. Abate G, Stapleton JT, Rouphael N, Creech B, Stout JE, El Sahly HM, Jackson L, Leyva FJ, Tomashek KM, Tibbals M, Watson N, Miller A, Charbek E, Siegner J, Sokol-Anderson M, Nayak R, Dahlberg G, Winokur P, Alaaeddine G, Beydoun N, Sokolow K, Kown NP, Phillips S, Baker AW, Turner N, Walter E, Guy E, Frey S. Clin Infect Dis. 2020 Mar 21. pii: ciaa252. doi: 10.1093/cid/ciaa252. [Epub ahead of print] PMID: 32198521 [PubMed - as supplied by publisher]

Charcot Joints From Cervical Myelopathy. Qin ES, Bettendorf B. J Clin Rheumatol. 2020 Mar 18. doi: 10.1097/RHU.0000000000001368. [Epub ahead of print] No abstract available.  PMID: 32195849 [PubMed - as supplied by publisher]

Targeting Myeloid-Specific Integrin α9β1 Improves Short and Long-Term Stroke Outcomes in Murine Models With Preexisting Comorbidities by Limiting Thrombosis And Inflammation. Dhanesha N, Jain M, Tripathi A, Doddapattar P, Chorawala M, Bathla G, Nayak MK, Ghatge M, Lentz SR, Kon S, Chauhan AK. Circ Res. 2020 Mar 20. doi: 10.1161/CIRCRESAHA.120.316659. [Epub ahead of print] PMID: 32195632 [PubMed - as supplied by publisher]

ATF4 Is a Fundamental Regulator of Nutrient Sensing and Protein Turnover. Rasmussen BB, Adams CM. J Nutr. 2020 Mar 19. pii: nxaa067. doi: 10.1093/jn/nxaa067. [Epub ahead of print] No abstract available.  PMID: 32190894 [PubMed - as supplied by publisher]

Central Nervous System Depressants and Risk of Hospitalization due to Community Acquired Pneumonia in the Very Old. Espinosa J, Alvarez P, Castro V, Caceres M, Soler-Riera M, Bril F. Curr Drug Saf. 2020 Mar 19. doi: 10.2174/1574886315666200319110114. [Epub ahead of print] PMID: 32189596 [PubMed - as supplied by publisher]

Rationale and Design of the Aspirin Dosing-A Patient-Centric Trial Assessing Benefits and Long-term Effectiveness (ADAPTABLE) Trial. Marquis-Gravel G, Roe MT, Robertson HR, Harrington RA, Pencina MJ, Berdan LG, Hammill BG, Faulkner M, Muñoz D, Fonarow GC, Nallamothu BK, Fintel DJ, Ford DE, Zhou L, Daugherty SE, Nauman E, Kraschnewski J, Ahmad FS, Benziger CP, Haynes K, Merritt JG, Metkus T, Kripalani S, Gupta K, Shah RC, McClay JC, Re RN, Geary C, Lampert BC, Bradley SM, Jain SK, Seifein H, Whittle J, Roger VL, Effron MB, Alvarado G, Goldberg YH, VanWormer JL, Girotra S, Farrehi P, McTigue KM, Rothman R, Hernandez AF, Jones WS. JAMA Cardiol. 2020 Mar 18. doi: 10.1001/jamacardio.2020.0116. [Epub ahead of print] PMID: 32186653 [PubMed - as supplied by publisher]

Inflammation in Areas of Fibrosis: The DeKAF Prospective Cohort. Matas AJ, Helgeson ES, Gaston R, Cosio F, Mannon R, Kasiske BL, Hunsicker L, Gourishankar S, Rush D, Cecka JM, Connett J, Grande J. Am J Transplant. 2020 Mar 17. doi: 10.1111/ajt.15862. [Epub ahead of print] PMID: 32185865 [PubMed - as supplied by publisher]

ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1). Weskamp G, Tüshaus J, Li D, Feederle R, Maretzky T, Swendemann S, Falck-Pedersen E, McIlwain DR, Mak TW, Salmon JE, Lichtenthaler SF, Blobel CP. J Biol Chem. 2020 Mar 27;295(13):4350-4358. doi: 10.1074/jbc.RA119.011136. Epub 2020 Feb 14. PMID: 32060096 [PubMed - in process]

March 1-15, 2020

Establishment, optimisation and quantitation of a bioluminescent murine infection model of visceral leishmaniasis for systematic vaccine screening. Ong HB, Clare S, Roberts AJ, Wilson ME, Wright GJ. Sci Rep. 2020 Mar 13;10(1):4689. doi: 10.1038/s41598-020-61662-3. PMID: 32170135 [PubMed - as supplied by publisher]

Predictive Factors and Time to Development of Hepatic Decompensation in Patients with Non-alcoholic Fatty Liver Disease. Ahmed HS, Pedersen N, Jayanna MB, Ten Eyck P, Sanchez A, Murali AR. J Gen Intern Med. 2020 Mar 10. doi: 10.1007/s11606-020-05725-1. [Epub ahead of print] PMID: 32157645 [PubMed - as supplied by publisher]

Time to Sustained Improvement in Bowel Movement Frequency with Telotristat Ethyl: Analyses of Phase III Studies in Carcinoid Syndrome. Dillon JS, Kulke MH, Hörsch D, Anthony LB, Warner RRP, Bergsland E, Welin S, O'Dorisio TM, Kunz PL, McKee C, Lapuerta P, Banks P, Pavel M. J Gastrointest Cancer. 2020 Mar 7. doi: 10.1007/s12029-020-00375-2. [Epub ahead of print] PMID: 32146619 [PubMed - as supplied by publisher]

COUNTERPOINT: Should the Use of Diagnostic Point-of-Care Ultrasound in Patient Care Require Hospital Privileging/Credentialing? No. Kruser JM, Schmidt GA, Kory PD. Chest. 2020 Mar;157(3):498-500. doi: 10.1016/j.chest.2019.10.037. No abstract available.  PMID: 32145806 [PubMed - in process]

Factors Associated with Health Insurance Affordability Concerns Among U.S. Adults Age 50-64: a Cross-Sectional, Nationally Representative Study. Scherer AM, Solway E, Malani PN, Luster J, Kullgren JT, Kirch M, Tipirneni R. J Gen Intern Med. 2020 Mar 6. doi: 10.1007/s11606-020-05732-2. [Epub ahead of print] No abstract available.  PMID: 32144696 [PubMed - as supplied by publisher]

Deletion of a neuronal Drp1 activator protects against cerebral ischemia. Flippo KH, Lin Z, Dickey AS, Zhou X, Dhanesha NA, Walters GC, Liu Y, Merrill RA, Meller R, Simon RP, Chauhan AK, Usachev YM, Strack S. J Neurosci. 2020 Mar 3. pii: JN-RM-1926-19. doi: 10.1523/JNEUROSCI.1926-19.2020. [Epub ahead of print] PMID: 32144179 [PubMed - as supplied by publisher]

Management issues in rheumatoid arthritis-associated interstitial lung disease. England BR, Hershberger D. Curr Opin Rheumatol. 2020 Mar 5. doi: 10.1097/BOR.0000000000000703. [Epub ahead of print] PMID: 32141954 [PubMed - as supplied by publisher]

Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals. Leisman DE, Harhay MO, Lederer DJ, Abramson M, Adjei AA, Bakker J, Ballas ZK, Barreiro E, Bell SC, Bellomo R, Bernstein JA, Branson RD, Brusasco V, Chalmers JD, Chokroverty S, Citerio G, Collop NA, Cooke CR, Crapo JD, Donaldson G, Fitzgerald DA, Grainger E, Hale L, Herth FJ, Kochanek PM, Marks G, Moorman JR, Ost DE, Schatz M, Sheikh A, Smyth AR, Stewart I, Stewart PW, Swenson ER, Szymusiak R, Teboul JL, Vincent JL, Wedzicha JA, Maslove DM. Crit Care Med. 2020 Mar 4. doi: 10.1097/CCM.0000000000004246. [Epub ahead of print] PMID: 32141923 [PubMed - as supplied by publisher]

A randomized control trial evaluating efficacy of antimicrobial impregnated hospital privacy curtains in an intensive care setting. Wilson G, Jackson V, Boyken L, Puig-Asensio M, Marra AR, Perencevich E, Schweizer ML, Diekema D, Breheny P, Petersen C. Am J Infect Control. 2020 Mar 2. pii: S0196-6553(20)30003-1. doi: 10.1016/j.ajic.2019.12.024. [Epub ahead of print] PMID: 32139090 [PubMed - as supplied by publisher]

Loss of iRhom2 accelerates fat gain and insulin resistance in diet-induced obesity despite reduced adipose tissue inflammation. Skurski J, Penniman CM, Geesala R, Dixit G, Pulipati P, Bhardwaj G, Meyerholz DK, Issuree PD, O'Neill BT, Maretzky T. Metabolism. 2020 Mar 2:154194. doi: 10.1016/j.metabol.2020.154194. [Epub ahead of print] PMID: 32135161 [PubMed - as supplied by publisher]

Munc13 mediates klotho-inhibitable diacylglycerol-stimulated exocytotic insertion of pre-docked TRPC6 vesicles. Xie J, An SW, Jin X, Gui Y, Huang CL. PLoS One. 2020 Mar 5;15(3):e0229799. doi: 10.1371/journal.pone.0229799. eCollection 2020. PMID: 32134975 [PubMed - in process] 

WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis. Sie ZL, Li RY, Sampurna BP, Hsu PJ, Liu SC, Wang HD, Huang CL, Yuh CH. Cancers (Basel). 2020 Mar 2;12(3). pii: E575. doi: 10.3390/cancers12030575. PMID: 32131390 [PubMed] 

Impact of liver tumour burden, alkaline phosphatase elevation, and target lesion size on treatment outcomes with ¹⁷⁷Lu-Dotatate: an analysis of the NETTER-1 study. Strosberg J, Kunz PL, Hendifar A, Yao J, Bushnell D, Kulke MH, Baum RP, Caplin M, Ruszniewski P, Delpassand E, Hobday T, Verslype C, Benson A, Srirajaskanthan R, Pavel M, Mora J, Berlin J, Grande E, Reed N, Seregni E, Paganelli G, Severi S, Morse M, Metz DC, Ansquer C, Courbon F, Al-Nahhas A, Baudin E, Giammarile F, Taïeb D, Mittra E, Wolin E, O'Dorisio TM, Lebtahi R, Deroose CM, Grana CM, Bodei L, Öberg K, Polack BD, He B, Mariani MF, Gericke G, Santoro P, Erion JL, Ravasi L, Krenning E; NETTER-1 study group. Eur J Nucl Med Mol Imaging. 2020 Mar 2. doi: 10.1007/s00259-020-04709-x. [Epub ahead of print] PMID: 32123969 [PubMed - as supplied by publisher]

Integrin β1D Deficiency-Mediated RyR2 Dysfunction Contributes to Catecholamine-Sensitive Ventricular Tachycardia in ARVC. Wang Y, Li C, Shi L, Chen X, Cui C, Huang J, Chen B, Hall DD, Pan Z, Lu M, Hong J, Song LS, Zhao S. Circulation. 2020 Mar 3. doi: 10.1161/CIRCULATIONAHA.119.043504. [Epub ahead of print] PMID: 32122157 [PubMed - as supplied by publisher]

Practicing the Ethics we Teach in International Medical Education. Kaldjian LC. Med Educ. 2020 Mar 2. doi: 10.1111/medu.14143. [Epub ahead of print] PMID: 32119149 [PubMed - as supplied by publisher]

A randomized phase II trial to compare safety and immunogenicity of the MVA-BN smallpox vaccine at various doses in adults with a history of AIDS. Overton ET, Lawrence SJ, Stapleton JT, Weidenthaler H, Schmidt D, Koenen B, Silbernagl G, Nopora K, Chaplin P. Vaccine. 2020 Mar 4;38(11):2600-2607. doi: 10.1016/j.vaccine.2020.01.058. Epub 2020 Feb 11. PMID: 32057574 [PubMed - in process]

Iron Deficiency in Chronic Kidney Disease: Updates on Pathophysiology, Diagnosis, and Treatment. Batchelor EK, Kapitsinou P, Pergola PE, Kovesdy CP, Jalal DI. J Am Soc Nephrol. 2020 Mar;31(3):456-468. doi: 10.1681/ASN.2019020213. Epub 2020 Feb 10. Review. PMID: 32041774 [PubMed - in process]

Meta-Analysis Evaluating Calcium Channel Blockers and the Risk of Peripheral Arterial Disease in Patients With Hypertension. Shetty S, Malik AH, Feringa H, El Accaoui R, Girotra S. Am J Cardiol. 2020 Mar 15;125(6):907-915. doi: 10.1016/j.amjcard.2019.12.026. Epub 2019 Dec 27. PMID: 31959429 [PubMed - in process]

Immunologic dysfunction and Hodgkin lymphoma: Insight to better therapy? Link BK. J Allergy Clin Immunol. 2020 Mar;145(3):780-781. doi: 10.1016/j.jaci.2019.12.914. Epub 2020 Jan 18. No abstract available. PMID: 31958473 [PubMed - in process]

Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization. Lemke-Miltner CD, Blackwell SE, Yin C, Krug AE, Morris AJ, Krieg AM, Weiner GJ. J Immunol. 2020 Mar 1;204(5):1386-1394. doi: 10.4049/jimmunol.1900742. Epub 2020 Jan 17. PMID: 31953355 [PubMed - in process]

Targeting myeloid-cell specific integrin α9β1 inhibits arterial thrombosis in mice. Dhanesha N, Nayak MK, Doddapattar P, Jain M, Flora GD, Kon S, Chauhan AK. Blood. 2020 Mar 12;135(11):857-861. doi: 10.1182/blood.2019002846. PMID: 31951649 [PubMed - in process]

Non-infectious thoracic discitis: A diagnostic and management dilemma. A report of two cases with review of the literature. Singla A, Ryan A, Bennett DL, Streit JA, Mau B, Rozek M, Hitchon PW. Clin Neurol Neurosurg. 2020 Mar;190:105648. doi: 10.1016/j.clineuro.2019.105648. Epub 2020 Jan 7. Review. PMID: 31931336 [PubMed - in process]

Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease. Malireddi RKS, Gurung P, Kesavardhana S, Samir P, Burton A, Mummareddy H, Vogel P, Pelletier S, Burgula S, Kanneganti TD. J Exp Med. 2020 Mar 2;217(3). pii: e20191644. doi: 10.1084/jem.20191644. PMID: 31869420 [PubMed - in process]

Therapeutic Advances in the Management of Smoldering Myeloma. Khan R, Zahid U, Kollu V, Jahan N, Ali M, Tricot G, Anwer F. Am J Ther. 2020 Mar/Apr;27(2):e194-e203. doi: 10.1097/MJT.0000000000001034. PMID: 31842112 [PubMed - in process]

Veterans' preferences for tobacco treatment in primary care: A discrete choice experiment. Katz DA, Hamlin C, Vander Weg MW, Grant KM, Stewart Steffensmeier KR, Paez M, Hawley ST, Gaeth G. Patient Educ Couns. 2020 Mar;103(3):652-660. doi: 10.1016/j.pec.2019.10.002. Epub 2019 Oct 4. PMID: 31629558 [PubMed - in process]

Post-discharge oral antimicrobial use among hospitalized patients across an integrated national healthcare network. Feller J, Lund BC, Perencevich EN, Alexander B, Heintz B, Beck B, Nair R, Goto M, Livorsi DJ. Clin Microbiol Infect. 2020 Mar;26(3):327-332. doi: 10.1016/j.cmi.2019.09.016. Epub 2019 Oct 7. PMID: 31600582 [PubMed - in process]

Desensitization strategies: is it worth it? Kuppachi S, Axelrod DA. Transpl Int. 2020 Mar;33(3):251-259. doi: 10.1111/tri.13532. Epub 2020 Feb 5. Review. PMID: 31553805 [PubMed - in process]

Osteolytic disease in IL-6 and Myc dependent mouse model of human myeloma. Sun F, Cheng Y, Walsh SA, Acevedo MR, Jing X, Han SS, Pisano MD, Tomasson MH, Lichtenstein AK, Zhan F, Hari P, Janz S. Haematologica. 2020 Mar;105(3):e111-e115. doi: 10.3324/haematol.2019.221127. Epub 2019 Jun 20. No abstract available.  PMID: 31221780 [PubMed - in process]