Logo for University of Iowa Health Care This logo represents the University of Iowa Health Care

Recent Research Publications - November 2020

November 16-30, 2020

Internal Fixation Construct and Defect Size Affect Healing of a Translational Porcine Diaphyseal Tibial Segmental Bone Defect. McKinley TO, Natoli RM, Fischer JP, Rytlewski JD, Scofield DC, Usmani R, Kuzma A, Griffin KS, Jewell E, Childress P, Shively KD, Chu TG, Anglen JO, Kacena MA. Mil Med. 2020 Nov 26:usaa516. doi: 10.1093/milmed/usaa516. Online ahead of print. PMID: 33242094

Reproductive Endocrinology Reference Intervals for Transgender Men on Stable Hormone Therapy. Greene DN, Schmidt RL, Winston-McPherson G, Rongitsch J, Imborek KL, Dickerson JA, Drees JC, Humble RM, Nisly N, Dole NJ, Dane SK, Frerichs J, Krasowski MD. J Appl Lab Med. 2020 Nov 26:jfaa169. doi: 10.1093/jalm/jfaa169. Online ahead of print. PMID: 33241847

Using race to estimate glomerular filtration and its impact in kidney transplantation. Kuppachi S, Norman SP, Lentine KL, Axelrod DA. Clin Transplant. 2020 Nov 24:e14136. doi: 10.1111/ctr.14136. Online ahead of print. PMID: 33232529

A randomized, open-label, phase 2, multicenter trial of gemcitabine with pazopanib or gemcitabine with docetaxel in patients with advanced soft-tissue sarcoma. Somaiah N, Van Tine BA, Wahlquist AE, Milhem MM, Hill EG, Garrett-Mayer E, Armeson KE, Schuetze SM, Meyer CF, Reuben DY, Elias AD, Read WL, Chawla SP, Kraft AS. Cancer. 2020 Nov 24. doi: 10.1002/cncr.33216. Online ahead of print. PMID: 33231866

THE EFFECTS OF DIET COMPOSITION AND CHRONIC OBESITY ON MUSCLE GROWTH AND FUNCTION. de Sousa LGO, Marshall AG, Norman JE, Fuqua JD, Lira VA, Rutledge JC, Bodine SC. J Appl Physiol (1985). 2020 Nov 19. doi: 10.1152/japplphysiol.00156.2020. Online ahead of print. PMID: 33211595

Repurposing Anti-Cancer Drugs for COVID-19 Treatment. Borcherding N, Jethava Y, Vikas P. Drug Des Devel Ther. 2020 Nov 18;14:5045-5058. doi: 10.2147/DDDT.S282252. eCollection 2020. PMID: 33239864 Free PMC article. Review.

Incorporating Surgical Ergonomics Education into Surgical Residency Curriculum. Jensen MJ, Liao J, Van Gorp B, Sugg SL, Shelton J, Corwin C, Lal G. J Surg Educ. 2020 Nov 18:S1931-7204(20)30429-3. doi: 10.1016/j.jsurg.2020.11.004. Online ahead of print. PMID: 33221251

Publisher Correction: Mitochondrial pyruvate carriers are required for myocardial stress adaptation. Zhang Y, Taufalele PV, Cochran JD, Robillard-Frayne I, Marx JM, Soto J, Rauckhorst AJ, Tayyari F, Pewa AD, Gray LR, Teesch LM, Puchalska P, Funari TR, McGlauflin R, Zimmerman K, Kutschke WJ, Cassier T, Hitchcock S, Lin K, Kato KM, Stueve JL, Haff L, Weiss RM, Cox JE, Rutter J, Taylor EB, Crawford PA, Lewandowski ED, Des Rosiers C, Abel ED. Nat Metab. 2020 Nov 18. doi: 10.1038/s42255-020-00322-2. Online ahead of print. PMID: 33208925

Endoscopic mucosal resection for early esophageal carcinoma is effective and safe but necessitates continued surveillance. Hasan Y, Murali AR, Gerke H. Indian J Gastroenterol. 2020 Nov 17. doi: 10.1007/s12664-020-01084-1. Online ahead of print. PMID: 33201442

Predator Scent-Induced Sensitization of Hypertension and Anxiety-like Behaviors. Xue B, Xue J, Yu Y, Wei SG, Beltz TG, Felder RB, Johnson AK. Cell Mol Neurobiol. 2020 Nov 17. doi: 10.1007/s10571-020-01005-y. Online ahead of print. PMID: 33201417

Better Nurse Staffing Is Associated With Survival for Black Patients and Diminishes Racial Disparities in Survival After In-Hospital Cardiac Arrests. Brooks Carthon M, Brom H, McHugh M, Sloane DM, Berg R, Merchant R, Girotra S, Aiken LH. Med Care. 2020 Nov 16. doi: 10.1097/MLR.0000000000001464. Online ahead of print. PMID: 33201082

Patient Adherence to Screening for Lung Cancer in the US: A Systematic Review and Meta-analysis. Lopez-Olivo MA, Maki KG, Choi NJ, Hoffman RM, Shih YT, Lowenstein LM, Hicklen RS, Volk RJ. JAMA Netw Open. 2020 Nov 2;3(11):e2025102. doi: 10.1001/jamanetworkopen.2020.25102. PMID: 33196807 Free PMC article.

Surgical Management of Neuroendocrine Tumor Liver Metastases. Tran CG, Sherman SK, Chandrasekharan C, Howe JR. Surg Oncol Clin N Am. 2021 Jan;30(1):39-55. doi: 10.1016/j.soc.2020.08.001. Epub 2020 Oct 20. PMID: 33220808 Review.

Short- and Long-Term Outcomes in Patients With New-Onset Persistent Left Bundle Branch Block After Transcatheter Aortic Valve Replacement. Megaly M, Abraham B, Abdelsalam M, Saad M, Omer M, Elbadawi A, Mentias A, Narayanan MA, Gafoor S, Brilakis ES, Goessl M, Cavalcante JL, Garcia S, Kapadia S, Pershad A, Sorajja P, Sengupta J. Cardiovasc Revasc Med. 2020 Oct;21(10):1299-1304. doi: 10.1016/j.carrev.2020.03.009. Epub 2020 Mar 7. PMID: 33246556

November 1-15, 2020

UDCA Decreases Incidence of Primary Biliary Cholangitis and Biliary Complications after Liver Transplant: A Meta-Analysis. Pedersen MR, Greenan G, Arora S, Murali A, Mayo MJ. Liver Transpl. 2020 Nov 13. doi: 10.1002/lt.25935. Online ahead of print. PMID: 33185320

Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers. Dunican EM, Elicker BM, Henry T, Gierada DS, Schiebler ML, Anderson W, Barjaktarevic I, Barr RG, Bleecker ER, Boucher RC, Bowler RP, Christenson SA, Comellas A, Cooper CB, Couper D, Criner GJ, Dransfield M, Doerschuk CM, Drummond MB, Hansel NN, Han MK, Hastie AT, Hoffman EA, Krishnan JA, Lazarus SC, Martinez FJ, McCulloch CE, O'Neal WK, Ortega VE, Paine R 3rd, Peters S, Schroeder JD, Woodruff PG, Fahy JV. Am J Respir Crit Care Med. 2020 Nov 12. doi: 10.1164/rccm.202006-2248OC. Online ahead of print. PMID: 33180550

Neuropilin-1 directs PDGFRα-entry into lung fibroblasts and signaling from very early endosomes. McGowan SE, McCoy DM. Am J Physiol Lung Cell Mol Physiol. 2020 Nov 11. doi: 10.1152/ajplung.00149.2020. Online ahead of print. PMID: 33174445

Collagen networks within 3D PEG hydrogels support valvular interstitial cell matrix mineralization. Schroeder ME, Rodriguez AG, Speckl KF, Walker CJ, Midekssa FS, Grim JC, Weiss RM, Anseth KS. Acta Biomater. 2020 Nov 9:S1742-7061(20)30655-3. doi: 10.1016/j.actbio.2020.11.012. Online ahead of print. PMID: 33181362

Interaction between magnesium and methylglyoxal in diabetic polyneuropathy and neuronal models. Strom A, Strassburger K, Schmuck M, Shevalye H, Davidson E, Zivehe F, Bönhof G, Reimer R, Belgardt BF, Fleming T, Biermann B, Burkart V, Müssig K, Szendroedi J, Yorek MA, Fritsche E, Nawroth PP, Roden M, Ziegler D; GDS Group. Mol Metab. 2020 Nov 6:101114. doi: 10.1016/j.molmet.2020.101114. Online ahead of print. PMID: 33166742

Ceramides in Metabolism: Key Lipotoxic Players. Chaurasia B, Summers SA.Annu Rev Physiol. 2020 Nov 6. doi: 10.1146/annurev-physiol-031620-093815. Online ahead of print. PMID: 33158378

The smart activatable P2&3TT probe allows accurate, fast, and highly sensitive detection of Staphylococcus aureus in clinical blood culture samples. López-Álvarez M, Heuker M, Schoenmakers JWA, van Dam GM, McNamara JO 2nd, van Dijl JM, van Oosten M. Sci Rep. 2020 Nov 5;10(1):19216. doi: 10.1038/s41598-020-76254-4. PMID: 33154413 Free PMC article.

Trends, Perioperative Adverse Events, and Survival of Patients With Left Ventricular Assist Devices Undergoing Noncardiac Surgery. Mentias A, Briasoulis A, Vaughan Sarrazin MS, Alvarez PA. JAMA Netw Open. 2020 Nov 2;3(11):e2025118. doi: 10.1001/jamanetworkopen.2020.25118. PMID: 33180131

A 28-Year-Old Pregnant Woman With a Lung Abscess and Complicated Pleural Effusion. Llanos O, Lee S, Salinas JL, Sanchez R. Chest. 2020 Nov;158(5):e233-e236. doi: 10.1016/j.chest.2020.07.008. PMID: 33160543

Correction to: A Nonsense N -Terminus NFKB2 Mutation Leading to Haploinsufficiency in a Patient with a Predominantly Antibody Deficiency. Kuehn HS, Bernasconi A, Niemela JE, Almejun MB, Gallego WAF, Goel S, Stoddard JL, Sánchez RGP, Franco CAA, Oleastro M, Grunebaum E, Ballas Z, Cunningham-Rundles C, Fleisher TA, Franco JL, Danielian S, Rosenzweig SD. J Clin Immunol. 2020 Nov;40(8):1102. doi: 10.1007/s10875-020-00860-0. PMID: 32901356

Estimated Glomerular Filtration Rate at Transplant Listing and Other Predictors of Post-Heart Transplant Mortality and the Development of ESRD. Kumar A, Howard A, Thomas CP. Transplantation. 2020 Nov;104(11):2444-2452. doi: 10.1097/TP.0000000000003159. PMID: 32028343

Mitochondrial pyruvate carriers are required for myocardial stress adaptation. Zhang Y, Taufalele PV, Cochran JD, Robillard-Frayne I, Marx JM, Soto J, Rauckhorst AJ, Tayyari F, Pewa AD, Gray LR, Teesch LM, Puchalska P, Funari TR, McGlauflin R, Zimmerman K, Kutschke WJ, Cassier T, Hitchcock S, Lin K, Kato KM, Stueve JL, Haff L, Weiss RM, Cox JE, Rutter J, Taylor EB, Crawford PA, Lewandowski ED, Des Rosiers C, Abel ED. Nat Metab. 2020 Nov;2(11):1248-1264. doi: 10.1038/s42255-020-00288-1. Epub 2020 Oct 26. PMID: 33106689

Modulation of phagocytosis-induced cell death of human neutrophils by Neisseria gonorrhoeae. Cho C, Teghanemt A, Apicella MA, Nauseef WM. J Leukoc Biol. 2020 Nov;108(5):1543-1553. doi: 10.1002/JLB.4MA0820-649R. Epub 2020 Sep 25. PMID: 32977356

Genetic deletion of miR-204 improves glycemic control despite obesity in db/db mice. Gaddam RR, Kim YR, Li Q, Jacobs JS, Gabani M, Mishra A, Promes JA, Imai Y, Irani K, Vikram A. Biochem Biophys Res Commun. 2020 Nov 5;532(2):167-172. doi: 10.1016/j.bbrc.2020.08.077. Epub 2020 Sep 17. PMID: 32950230

Secreted Factors From Proinflammatory Macrophages Promote an Osteoblast-Like Phenotype in Valvular Interstitial Cells. Grim JC, Aguado BA, Vogt BJ, Batan D, Andrichik CL, Schroeder ME, Gonzalez-Rodriguez A, Yavitt FM, Weiss RM, Anseth KS. Arterioscler Thromb Vasc Biol. 2020 Nov;40(11):e296-e308. doi: 10.1161/ATVBAHA.120.315261. Epub 2020 Sep 17. PMID: 32938214

Circadian variation of in-hospital cardiac arrest. Tripathi A, Girotra S, Toft LEB; American Heart Association's Get With the Guidelines-Resuscitation Investigators. Resuscitation. 2020 Nov;156:19-26. doi: 10.1016/j.resuscitation.2020.08.014. Epub 2020 Aug 25. PMID: 32853726

Minimal Change Disease With Nephrotic Syndrome Associated With Coronavirus Disease 2019 After Apolipoprotein L1 Risk Variant Kidney Transplant: A Case Report. Yamada M, Rastogi P, Ince D, Thayyil A, Adela Mansilla M, Smith RJH, Kuppachi S, Thomas CP. Transplant Proc. 2020 Nov;52(9):2693-2697. doi: 10.1016/j.transproceed.2020.08.012. Epub 2020 Aug 20. PMID: 32972761 Free PMC article.

A Nonsense N -Terminus NFKB2 Mutation Leading to Haploinsufficiency in a Patient with a Predominantly Antibody Deficiency. Kuehn HS, Bernasconi A, Niemela JE, Almejun MB, Gallego WAF, Goel S, Stoddard JL, Sánchez RGP, Franco CAA, Oleastro M, Grunebaum E, Ballas Z, Cunningham-Rundles C, Fleisher TA, Franco JL, Danielian S, Rosenzweig SD. J Clin Immunol. 2020 Nov;40(8):1093-1101. doi: 10.1007/s10875-020-00842-2. Epub 2020 Aug 19. PMID: 32813180 Free PMC article.

Do ICD diagnostics predict failure of ventricular tachycardia response to antitachycardia pacing and need for shock? Al-Damluji MS, Singhvi A, Snuckel M, Zaghloul A, Kluger J. Pacing Clin Electrophysiol. 2020 Nov;43(11):1302-1308. doi: 10.1111/pace.14002. Epub 2020 Aug 13. PMID: 32617992

Early pathogenesis of cystic fibrosis gallbladder disease in a porcine model. Zarei K, Stroik MR, Gansemer ND, Thurman AL, Ostedgaard LS, Ernst SE, Thornell IM, Powers LS, Pezzulo AA, Meyerholz DK, Stoltz DA. Lab Invest. 2020 Nov;100(11):1388-1399. doi: 10.1038/s41374-020-0474-8. Epub 2020 Jul 27. PMID: 32719544

Clinical image: chronic skin ulcers in a patient with rheumatoid arthritis on immunosuppressant therapy. Kobayashi T, Swick BL, Cho C. Clin Rheumatol. 2020 Nov;39(11):3517-3518. doi: 10.1007/s10067-020-05251-9. Epub 2020 Jun 26. PMID: 32592006 No abstract available.

Esophageal cooling for protection during left atrial ablation: a systematic review and meta-analysis. Leung LW, Gallagher MM, Santangeli P, Tschabrunn C, Guerra JM, Campos B, Hayat J, Atem F, Mickelsen S, Kulstad E. J Interv Card Electrophysiol. 2020 Nov;59(2):347-355. doi: 10.1007/s10840-019-00661-5. Epub 2019 Nov 22. PMID: 31758504 Free PMC article.