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Recent Publications - December 2021

December 16-31, 2021

Correction to: Whole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility.  Bruse S, Moreau M, Bromberg Y, Jang JH, Wang N, Ha H, Picchi M, Lin Y, Langley RJ, Qualls C, Klesney-Tait J, Zabner J, Leng S, Mao J, Belinsky SA, Xing J, Nyunoya T. Hum Genomics. 2021 Dec 30;15(1):74. doi: 10.1186/s40246-021-00373-w. PMID: 34965893 No abstract available.

Intralesional SD-101 in combination with pembrolizumab in anti-PD-1 treatment naive head and neck squamous cell carcinoma: results from a multicenter, phase 2 trial.  Cohen EEW, Nabell L, Wong DJ, Day T, Daniels GA, Milhem M, Deva S, Jameson M, Guntinas-Lichius O, Almubarak M, Strother M, Whitman E, Chisamore M, Obiozor C, Bagulho T, Gomez-Romo J, Guiducci C, Janssen R, Gamelin E, Algazi AP. Clin Cancer Res. 2021 Dec 29:clincanres.1411.2021. doi: 10.1158/1078-0432.CCR-21-1411. Online ahead of print. PMID: 34965944

Transforming Growth Factor-α Acts in Hypothalamic Paraventricular Nucleus to Upregulate ERK1/2 Signaling and Expression of Sympathoexcitatory Mediators in Heart Failure Rats.  Yu Y, Chen E, Weiss RM, Felder RB, Wei SG. Neuroscience. 2021 Dec 27:S0306-4522(21)00654-0. doi: 10.1016/j.neuroscience.2021.12.030. Online ahead of print. PMID: 34968668

HIV-infection and cocaine use regulate semen extracellular vesicles proteome and miRNAome in a manner that mediates strategic monocyte haptotaxis governed by miR-128 network.  Kaddour H, Kopcho S, Lyu Y, Shouman N, Paromov V, Pratap S, Dash C, Kim EY, Martinson J, McKay H, Epeldegui M, Margolick JB, Stapleton JT, Okeoma CM. Cell Mol Life Sci. 2021 Dec 22;79(1):5. doi: 10.1007/s00018-021-04068-2. PMID: 34936021

Comparison of Coronary Artery Calcium Scoring with Dobutamine Stress Echo for Detection of Coronary Artery Disease Before Liver Transplantation.  Kleb C, Jain V, Sheth C, Wolski K, Kapadia S, Grimm R, Desai M, Krishnaswamy A, Kassis N, Sheng C, Zheng H, Cywinski J, Menon KVN, Eghtesad B, Diago Uso T, Quintini C, Schoenhagen P, Harb SC, Sharma V, Fares M. Ann Transplant. 2021 Dec 22;26:e934163. doi: 10.12659/AOT.934163. PMID: 34934037

Human T cells express Angiotensin Converting Enzyme 2 at levels sufficient to interact with the SARS-CoV-2 Spike protein.  Welch JL, Xiang J, Chang Q, Houtman JCD, Stapleton JT. J Infect Dis. 2021 Dec 16:jiab595. doi: 10.1093/infdis/jiab595. Online ahead of print. PMID: 34918095

Reconsidering the Utility of Race-Specific Lung Function Prediction Equations.  Baugh AD, Shiboski S, Hansel NN, Ortega V, Barjakteravic I, Barr RG, Bowler R, Comellas AP, Cooper CB, Couper D, Criner G, Curtis JL, Dransfield M, Ejike C, Han M, Hoffman E, Krishnan J, Krishnan JA, Mannino D, Paine Iii R, Parekh T, Peters S, Putcha N, Rennard S, Thakur N, Woodruff PG. Am J Respir Crit Care Med. 2021 Dec 16. doi: 10.1164/rccm.202105-1246OC. Online ahead of print. PMID: 34913855

December 1-15, 2021

Deciphering regulatory protein activity in human pancreatic islets via reverse engineering of single-cell sequencing data.  Imai Y. J Clin Invest. 2021 Dec 15;131(24):e154482. doi: 10.1172/JCI154482. PMID: 34907912

Use of Communication Technology to Improve Clinical Trial Participation in Adolescents and Young Adults With Cancer: Consensus Statement From the Children's Oncology Group Adolescent and Young Adult Responsible Investigator Network.  Avutu V, Monga V, Mittal N, Saha A, Andolina JR, Bell DE, Fair DB, Flerlage JE, Frediani JN, Heath JL, Kahn JM, Reichek JL, Super L, Terao MA, Freyer DR, Roth ME. JCO Oncol Pract. 2021 Dec 14:OP2100554. doi: 10.1200/OP.21.00554. Online ahead of print. PMID: 34905405

Combining Ivacaftor and Intensive Antibiotics Achieves Limited Clearance of Cystic Fibrosis Infections.  Durfey SL, Pipavath S, Li A, Vo AT, Ratjen A, Carter S, Morgan SJ, Radey MC, Grogan B, Salipante SJ, Welsh MJ, Stoltz DA, Goss CH, McKone EF, Singh PK. mBio. 2021 Dec 14:e0314821. doi: 10.1128/mbio.03148-21. Online ahead of print. PMID: 34903059

Bispecific antibody-activated T cells enhance NK cell-mediated antibody-dependent cellular cytotoxicity.  Wang Z, Yin C, Lum LG, Simons A, Weiner GJ. J Hematol Oncol. 2021 Dec 9;14(1):204. doi: 10.1186/s13045-021-01216-w. PMID: 34886888 Free PMC article.

Human miRNA miR-675 inhibits DUX4 expression and may be exploited as a potential treatment for Facioscapulohumeral muscular dystrophy.  Saad NY, Al-Kharsan M, Garwick-Coppens SE, Chermahini GA, Harper MA, Palo A, Boudreau RL, Harper SQ. Nat Commun. 2021 Dec 8;12(1):7128. doi: 10.1038/s41467-021-27430-1. PMID: 34880230

Effect of Use of a Bougie vs Endotracheal Tube With Stylet on Successful Intubation on the First Attempt Among Critically Ill Patients Undergoing Tracheal Intubation: A Randomized Clinical Trial. Driver BE, Semler MW, Self WH, Ginde AA, Trent SA, Gandotra S, Smith LM, Page DB, Vonderhaar DJ, West JR, Joffe AM, Mitchell SH, Doerschug KC, Hughes CG, High K, Landsperger JS, Jackson KE, Howell MP, Robison SW, Gaillard JP, Whitson MR, Barnes CM, Latimer AJ, Koppurapu VS, Alvis BD, Russell DW, Gibbs KW, Wang L, Lindsell CJ, Janz DR, Rice TW, Prekker ME, Casey JD; BOUGIE Investigators and the Pragmatic Critical Care Research Group. JAMA. 2021 Dec 8. doi: 10.1001/jama.2021.22002. Online ahead of print. PMID: 34879143

Evaluation of a Case Series of Patients With Generalized Pustular Psoriasis in the United States.  Noe MH, Wan MT, Mostaghimi A, Gelfand JM; Pustular Psoriasis in the US Research Group, Agnihothri R, Armstrong AW, Bhutani T, Bridges A, Brownstone N, Butt M, Duffin KPC, Carr C, Creadore A, DeNiro KL, Desai S, Dominguez AR, Duffy EK, Fairley JA, Femia A, Gudjonsson JE, Kaffenberger JA, Katz KL, Le ST, Martinez E, Maverakis E, Myers B, Naik HB, Nelson CA, Ortega-Loayza AG, Plovanich ME, Rangel LK, Ravi V, Reddy VD, Saleh JZ, Kirby JS, Sandhu JK, Shakshouk H, Shields BE, Sharif-Sidi Z, Smith J, Steahr A, Toussi A, Wanat KA, Wang B, Wei BM, Weinhammer A, Worswick SD, Yang A. JAMA Dermatol. 2021 Dec 8. doi: 10.1001/jamadermatol.2021.4640. Online ahead of print. PMID: 34878491

Translating in vitro CFTR rescue into small molecule correctors for cystic fibrosis using the Library of Integrated Network-based Cellular Signatures drug discovery platform.  Strub MD, Ramachandran S, Boudko DY, Meleshkevitch EA, Pezzulo AA, Subramanian A, Liberzon A, Bridges RJ, McCray PB Jr. CPT Pharmacometrics Syst Pharmacol. 2021 Dec 8. doi: 10.1002/psp4.12751. Online ahead of print. PMID: 34877817

Impact of Sex and Metabolic Comorbidities on Coronavirus Disease 2019 (COVID-19) Mortality Risk Across Age Groups: 66 646 Inpatients Across 613 U.S. Hospitals.  Goodman KE, Magder LS, Baghdadi JD, Pineles L, Levine AR, Perencevich EN, Harris AD. Clin Infect Dis. 2021 Dec 6;73(11):e4113-e4123. doi: 10.1093/cid/ciaa1787. PMID: 33337474 Free PMC article.

Using nasal povidone-iodine to prevent bloodstream infections and transmission of Staphylococcus aureus among haemodialysis patients: a stepped-wedge cluster randomised control trial protocol. Racila AM, O'Shea AMJ, Nair R, Dukes K, Herwaldt LA, Boyken L, Diekema D, Ward MA, Cobb J, Jacob J, Pegues D, Bleasdale S, Vijayan A, Mutneja A, Fraer M, O'Connell-Moore D, Tolomeo P, Mendez M, Jaworski E, Schweizer ML. BMJ Open. 2021 Dec 3;11(12):e048830. doi: 10.1136/bmjopen-2021-048830. PMID: 34862278

Cardio-ankle vascular index of increased arterial wall stiffness is associated with neurocognitive impairment in well-controlled HIV.  Kaewpoowat Q, Rerkasem A, Rerkasem K, Robertson KR, Aita SL, Roth RM, Yasri S, Choovuthayakorn J, Ausayakhun S, Supparatpinyo K, Robbins NM. HIV Med. 2021 Dec 3. doi: 10.1111/hiv.13213. Online ahead of print. PMID: 34859556

A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β cells.  Li M, Shao F, Qian Q, Yu W, Zhang Z, Chen B, Su D, Guo Y, Phan AV, Song LS, Stephens SB, Sebag J, Imai Y, Yang L, Cao H. Mol Ther Nucleic Acids. 2021 Jul 16;26:307-320. doi: 10.1016/j.omtn.2021.06.027. eCollection 2021 Dec 3. PMID: 34513312 Free PMC article.

The clinical and molecular spectrum of QRICH1 associated neurodevelopmental disorder.  Kumble S, Levy AM, Punetha J, Gao H, Ah Mew N, Anyane-Yeboa K, Benke PJ, Berger SM, Bjerglund L, Campos-Xavier B, Ciliberto M, Cohen JS, Comi AM, Curry C, Damaj L, Denommé-Pichon AS, Emrick L, Faivre L, Fasano MB, Fiévet A, Finkel RS, García-Miñaúr S, Gerard A, Gomez-Puertas P, Guillen Sacoto MJ, Hoffman TL, Howard L, Iglesias AD, Izumi K, Larson A, Leiber A, Lozano R, Marcos-Alcalde I, Mintz CS, Mullegama SV, Møller RS, Odent S, Oppermann H, Ostergaard E, Pacio-Míguez M, Palomares-Bralo M, Parikh S, Paulson AM, Platzer K, Posey JE, Potocki L, Revah-Politi A, Rio M, Ritter AL, Robinson S, Rosenfeld JA, Santos-Simarro F, Sousa SB; Undiagnosed Diseases Network, Wéber M, Xie Y, Chung WK, Brown NJ, Tümer Z. Hum Mutat. 2021 Dec 2. doi: 10.1002/humu.24308. Online ahead of print. PMID: 34859529

Leveraging implementation science to advance antibiotic stewardship practice and research.  Livorsi DJ, Drainoni ML, Reisinger HS, Nanda N, McGregor JC, Barlam TF, Morris AM, Szymczak JE. Infect Control Hosp Epidemiol. 2021 Dec 2:1-8. doi: 10.1017/ice.2021.480. Online ahead of print. PMID: 34852212 No abstract available.

Health Care Utilization Among Texas Veterans Health Administration Enrollees Before and After Hurricane Harvey, 2016-2018.  Carrel M, Clore GS, Kim S, Vaughan Sarrazin M, Tate E, Perencevich EN, Goto M. JAMA Netw Open. 2021 Dec 1;4(12):e2138535. doi: 10.1001/jamanetworkopen.2021.38535. PMID: 34889944

Medical Education and the Ethics of Self-Care: A Survey of Medical Students Regarding Professional Challenges and Expectations for Living Healthy Lifestyles.  Rempel AML, Barlow PB, Kaldjian LC. South Med J. 2021 Dec;114(12):783-788. doi: 10.14423/SMJ.0000000000001333. PMID: 34853855

Activation of Crtc2/Creb1 in skeletal muscle enhances weight loss during intermittent fasting.  Bruno NE, Nwachukwu JC, Hughes DC, Srinivasan S, Hawkins R, Sturgill D, Hager GL, Hurst S, Sheu SS, Bodine SC, Conkright MD, Nettles KW. FASEB J. 2021 Dec;35(12):e21999. doi: 10.1096/fj.202100171R. PMID: 34748223

Zinc protoporphyrin binding to telomerase complexes and inhibition of telomerase activity.  Zhu Z, Tran H, Mathahs MM, Fink BD, Albert JA, Moninger TO, Meier JL, Li M, Schmidt WN. Pharmacol Res Perspect. 2021 Dec;9(6):e00882. doi: 10.1002/prp2.882. PMID: 34747573 Free PMC article.

Methionine as a double-edged sword in health and disease: Current perspective and future challenges.  Navik U, Sheth VG, Khurana A, Jawalekar SS, Allawadhi P, Gaddam RR, Bhatti JS, Tikoo K. Ageing Res Rev. 2021 Dec;72:101500. doi: 10.1016/j.arr.2021.101500. Epub 2021 Oct 23. PMID: 34700006

Mortality Correlates in Patients With Takotsubo Syndrome During the COVID-19 Pandemic.  Chang A, Wang YG, Jayanna MB, Wu X, Cadaret LM, Liu K. Mayo Clin Proc Innov Qual Outcomes. 2021 Dec;5(6):1050-1055. doi: 10.1016/j.mayocpiqo.2021.09.008. Epub 2021 Sep 29. PMID: 34604705 Free PMC article.

Single Center Experience with Isolated Spinal Cord Neurosarcoidosis.  Park BJ, Ray E, Bathla G, Bruch LA, Streit JA, Cho TA, Hitchon PW. World Neurosurg. 2021 Dec;156:e398-e407. doi: 10.1016/j.wneu.2021.09.089. Epub 2021 Sep 25. PMID: 34583004

Toll-like receptor 4 and myeloid differentiation factor 88 are required for gastric bypass-induced metabolic effects.  Abu El Haija M, Ye Y, Chu Y, Herz H, Linden B, Shahi SK, Zarei K, Mangalam AK, Mcelroy SJ, Mokadem M. Surg Obes Relat Dis. 2021 Dec;17(12):1996-2006. doi: 10.1016/j.soard.2021.07.019. Epub 2021 Aug 2. PMID: 34462225

Correction: The persistent lack of knowledge and misunderstanding of the Genetic Information Nondiscrimination Act (GINA) more than a decade after passage.  Lenartz A, Scherer AM, Uhlmann WR, Suter SM, Anderson Hartley C, Prince AER. Genet Med. 2021 Dec;23(12):2471. doi: 10.1038/s41436-021-01305-8. PMID: 34446926 No abstract available.

The persistent lack of knowledge and misunderstanding of the Genetic Information Nondiscrimination Act (GINA) more than a decade after passage.  Lenartz A, Scherer AM, Uhlmann WR, Suter SM, Anderson Hartley C, Prince AER. Genet Med. 2021 Dec;23(12):2324-2334. doi: 10.1038/s41436-021-01268-w. Epub 2021 Aug 16. PMID: 34400812

Executive Summary: Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert Panel Report.  Stevens SM, Woller SC, Baumann Kreuziger L, Bounameaux H, Doerschug K, Geersing GJ, Huisman MV, Kearon C, King CS, Knighton AJ, Lake E, Murin S, Vintch JRE, Wells PS, Moores LK. Chest. 2021 Dec;160(6):2247-2259. doi: 10.1016/j.chest.2021.07.056. Epub 2021 Aug 2. PMID: 34352279

Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert Panel Report.  Stevens SM, Woller SC, Kreuziger LB, Bounameaux H, Doerschug K, Geersing GJ, Huisman MV, Kearon C, King CS, Knighton AJ, Lake E, Murin S, Vintch JRE, Wells PS, Moores LK. Chest. 2021 Dec;160(6):e545-e608. doi: 10.1016/j.chest.2021.07.055. Epub 2021 Aug 2. PMID: 34352278

Directed movement toward, translocation along, penetration into and exit from vascular networks by breast cancer cells in 3D.  Wessels DJ, Pujol C, Pradhan N, Lusche DF, Gonzalez L, Kelly SE, Martin EM, Voss ER, Park YN, Dailey M, Sugg SL, Phadke S, Bashir A, Soll DR. Cell Adh Migr. 2021 Dec;15(1):224-248. doi: 10.1080/19336918.2021.1957527. PMID: 34338608 Free PMC article.

Impact of initial biopsy type on the time to final diagnostic biopsy in patients with follicular lymphoma and suspected histologic transformation.  Mou E, Falchi L, Sundaram V, Abramson JS, Balassanian R, Beygi S, Fitzpatrick MJ, Frank AK, Gupta S, Lin O, Reed JR, Long SR, Ly A, Menke JR, Reed DR, Ruiz-Cordero R, Volaric AK, Xie Y, Wang L, Wen KW, Zadeh SL, Natkunam Y, Cheung MC, Gratzinger D; Cyto-Heme Institutional Collaborative (CHIC) consortium. Leuk Lymphoma. 2021 Dec;62(12):2864-2872. doi: 10.1080/10428194.2021.1941936. Epub 2021 Jun 26. PMID: 34176413

A "Failed" Assay Development for the Discovery of Rescuing Small Molecules from the Radiation Damage.  Wen KK, Roy S, Grumbach IM, Wu M. SLAS Discov. 2021 Dec;26(10):1315-1325. doi: 10.1177/24725552211020678. Epub 2021 Jun 19. PMID: 34151632 Free PMC article.

Assessing factors for choosing a primary care specialty in medical students; A longitudinal study.  McDonald C, Henderson A, Barlow P, Keith J. Med Educ Online. 2021 Dec;26(1):1890901. doi: 10.1080/10872981.2021.1890901. PMID: 33829968 Free PMC article.

Initial optimal medical therapy with or without invasive strategy for stable coronary disease: a meta-analysis and systematic review.  Barbarawi M, Alabdouh A, Barbarawi O, Lakshman H, Alkasasbeh M, Khallad M, Radaideh Q. Coron Artery Dis. 2021 Dec 1;32(8):721-729. doi: 10.1097/MCA.0000000000001030. PMID: 33826538

Investigating the relationship between rosacea and use of vasodilatory medications in a hospital-wide population.  Abid R, Reid AT, Zafar F, Powers EM, Powers JG. J Am Acad Dermatol. 2021 Dec;85(6):1626-1627. doi: 10.1016/j.jaad.2020.11.070. Epub 2021 Feb 9. PMID: 33359782 No abstract available.

Atypical Large Vessel Vasculitis Presenting With Cholestatic Liver Abnormalities: Case-Based Review.  Sangha S, Lenert A, Dawoud S, Kaur A, Yazan H, Voigt MD, Lenert P. J Clin Rheumatol. 2021 Dec 1;27(8):e561-e567. doi: 10.1097/RHU.0000000000001596. PMID: 33065628 Review.

Well-Being, Burnout, and Resiliency Among Early-Career Rheumatologists: A Qualitative Study.  Kumar B, Swee ML, Suneja M, Iyer P. J Clin Rheumatol. 2021 Dec 1;27(8):e404-e411. doi: 10.1097/RHU.0000000000001485. PMID: 32658045