Recent Publications - January 2021

January 16-31, 2021

Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis. Rosu A, El Hachem N, Rapino F, Rouault-Pierre K, Jorssen J, Somja J, Ramery E, Thiry M, Nguyen L, Jacquemyn M, Daelemans D, Adams CM, Bonnet D, Chariot A, Close P, Bureau F, Desmet CJ. J Exp Med. 2021 Mar 1;218(3):e20200662. doi: 10.1084/jem.20200662. PMID: 33507234

Addition Of 131I MIBG To PRRT (90Y DOTATOC) For Personalized Treatment of Selected Patients with Neuroendocrine Tumors. Bushnell DL, Bodeker KL, O'Dorisio TM, Madsen MT, Menda Y, Graves SA, O'Dorisio MS, Zamba GKD. J Nucl Med. 2021 Jan 30:jnumed.120.254987. doi: 10.2967/jnumed.120.254987. Online ahead of print. PMID: 33517327

Expanding an Economic Evaluation of the Veterans Affairs (VA) Methicillin-resistant Staphylococcus aureus (MRSA) Prevention Initiative to Include Prevention of Infections From Other Pathogens. Nelson RE, Goto M, Samore MH, Jones M, Stevens VW, Evans ME, Schweizer ML, Perencevich EN, Rubin MA. Clin Infect Dis. 2021 Jan 29;72(Supplement_1):S50-S58. doi: 10.1093/cid/ciaa1591. PMID: 33512526

Comparative Effectiveness of Switching to Daptomycin Versus Remaining on Vancomycin Among Patients With Methicillin-resistant Staphylococcus aureus (MRSA) Bloodstream Infections.  Schweizer ML, Richardson K, Vaughan Sarrazin MS, Goto M, Livorsi DJ, Nair R, Alexander B, Beck BF, Jones MP, Puig-Asensio M, Suh D, Ohl M, Perencevich EN. Clin Infect Dis. 2021 Jan 29;72(Supplement_1):S68-S73. doi: 10.1093/cid/ciaa1572. PMID: 33512521

Mapping the immune environment in clear cell renal carcinoma by single-cell genomics. Borcherding N, Vishwakarma A, Voigt AP, Bellizzi A, Kaplan J, Nepple K, Salem AK, Jenkins RW, Zakharia Y, Zhang W. Commun Biol. 2021 Jan 27;4(1):122. doi: 10.1038/s42003-020-01625-6. PMID: 33504936 Free PMC article.

Call Center Remote Triage by Nurse Practitioners Was Associated With Fewer Subsequent Face-to-Face Healthcare Visits. Kaboli PJ, Augustine MR, Rose DE, Chawla N, Bouchard M, Hebert P. J Gen Intern Med. 2021 Jan 26:1-8. doi: 10.1007/s11606-020-06536-0. Online ahead of print. PMID: 33501532 Free PMC article.

Circulating exosomal microRNA expression patterns distinguish cardiac sarcoidosis from myocardial ischemia. Crouser ED, Julian MW, Bicer S, Ghai V, Kim TK, Maier LA, Gillespie M, Hamzeh NY, Wang K. PLoS One. 2021 Jan 26;16(1):e0246083. doi: 10.1371/journal.pone.0246083. eCollection 2021. PMID: 33497386

Enhancing engagement beyond the conference walls: analysis of Twitter use at #ICPIC2019 infection prevention and control conference. Martischang R, Tartari E, Kilpatrick C, Mackenzie G, Carter V, Castro-Sánchez E, Márquez-Villarreal H, Otter JA, Perencevich E, Silber D, Storr J, Tetro J, Voss A, Pittet D.Antimicrob Resist Infect Control. 2021 Jan 25;10(1):20. doi: 10.1186/s13756-021-00891-1. PMID: 33494810 Free PMC article.

COVID-19 Research Agenda for Healthcare Epidemiology. Mody L, Akinboyo IC, Babcock HM, Bischoff WE, Cheng VC, Chiotos K, Claeys KC, Coffey KC, Diekema DJ, Donskey CJ, Ellingson KD, Gilmartin HM, Gohil SK, Harris AD, Keller SC, Klein EY, Krein SL, Kwon JH, Lauring AS, Livorsi DJ, Lofgren ET, Merrill K, Milstone A, Monsees EA, Morgan DJ, Perri LP, Pfeiffer CD, Rock C, Saint S, Sickbert-Bennett E, Skelton F, Suda KJ, Talbot TR, Vaughn VM, Weber DJ, Wiemken TL, Yassin MH, Ziegler MJ, Anderson DJ; SHEA Research Committee. Infect Control Hosp Epidemiol. 2021 Jan 25:1-81. doi: 10.1017/ice.2021.25. Online ahead of print. PMID: 33487199

Factors Associated with Osteoporosis Management Among Veterans Who Received Androgen Deprivation Therapy for Prostate Cancer.  Solimeo SL, Lund BC, McCoy KD, Sarrazin MV, Hoffman R. J Gen Intern Med. 2021 Jan 22. doi: 10.1007/s11606-020-06418-5. Online ahead of print. PMID: 33483816 No abstract available.

Immunogenicity and safety of different dose schedules and antigen doses of an MF59-adjuvanted H7N9 vaccine in healthy adults aged 65 years and older.  Winokur P, El Sahly HM, Mulligan MJ, Frey SE, Rupp R, Anderson EJ, Edwards KM, Bernstein DI, Schmader K, Jackson LA, Chen WH, Hill H, Bellamy A; DMID 13-0034 H7N9 Vaccine Study Group. Vaccine. 2021 Jan 20:S0264-410X(20)31504-8. doi: 10.1016/j.vaccine.2020.11.051. Online ahead of print. PMID: 33485646

Tracking break-induced replication shows that it stalls at roadblocks. Liu L, Yan Z, Osia BA, Twarowski J, Sun L, Kramara J, Lee RS, Kumar S, Elango R, Li H, Dang W, Ira G, Malkova A. Nature. 2021 Jan 20. doi: 10.1038/s41586-020-03172-w. Online ahead of print. PMID: 33473214

Blocking LOXL2 and TGFβ1 signalling induces collagen I turnover in precision-cut lung slices derived from patients with idiopathic pulmonary fibrosis.  Wei Y, Dong W, Jackson J, Ho TC, Le Saux CJ, Brumwell A, Li X, Klesney-Tait J, Cohen ML, Wolters PJ, Chapman HA. Thorax. 2021 Jan 20:thoraxjnl-2020-215745. doi: 10.1136/thoraxjnl-2020-215745. Online ahead of print. PMID: 33472968

Staphylococcus aureus osteomyelitis causing Brodie's abscess of the tibia in an adult man. Chen BC, Kobayashi T, O'Rourke H, Sekar P. BMJ Case Rep. 2021 Jan 18;14(1):e240836. doi: 10.1136/bcr-2020-240836. PMID: 33462070 No abstract available.

Utilization of redox modulating small molecules that selectively act as pro-oxidants in cancer cells to open a therapeutic window for improving cancer therapy. Petronek MS, Stolwijk JM, Murray SD, Steinbach EJ, Zakharia Y, Buettner GR, Spitz DR, Allen BG. Redox Biol. 2021 Jan 16:101864. doi: 10.1016/j.redox.2021.101864. Online ahead of print. PMID: 33485837

Meta-analysis of Transcatheter Aortic Valve Implantation in Patients with Stenotic Bicuspid vs. Tricuspid Aortic Valve. Majmundar M, Kumar A, Doshi R, Shah P, Arora S, Shariff M, Adalja D, Visco F, Amin H, Vallabhajosyula S, Gullapalli N, Kapadia SR, Kalra A, Panaich SS. Am J Cardiol. 2021 Jan 15:S0002-9149(21)00043-6. doi: 10.1016/j.amjcard.2020.12.085. Online ahead of print. PMID: 33460604

The anti-tumor effects of cetuximab in combination with VTX-2337 are T cell dependent.  Cheng Y, Borcherding N, Ogunsakin A, Lemke-Miltner CD, Gibson-Corley KN, Rajan A, Choi AB, Wongpattaraworakul W, Chan CHF, Salem AK, Weiner GJ, Simons AL. Sci Rep. 2021 Jan 15;11(1):1535. doi: 10.1038/s41598-020-80957-z. PMID: 33452311 Free PMC article.

Combination therapies for MPNSTs targeting RABL6A-RB1 signaling. Kohlmeyer JL, Gordon DJ, Tanas MR, Dodd RD, Monga V, Darbro BW, Quelle DE. Oncotarget. 2021 Jan 5;12(1):10-14. doi: 10.18632/oncotarget.27862. eCollection 2021 Jan 5. PMID: 33456709 Free PMC article.

Prosthetic Finger Joint Infection Due to Aspergillus terreus. Kobayashi T, Lawler E, Samra H, Ford B, Sekar P. Open Forum Infect Dis. 2020 Dec 13;8(1):ofaa614. doi: 10.1093/ofid/ofaa614. eCollection 2021 Jan. PMID: 33511236 Free PMC article.

A pathogenic germline BRCA2 variant in a patient with hypopharyngeal squamous cell carcinoma. Correa T, Laux DE, Hoffman HT. Clin Case Rep. 2020 Nov 25;9(1):429-432. doi: 10.1002/ccr3.3548. eCollection 2021 Jan. PMID: 33489192 Free PMC article.

ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).  Weskamp G, Tüshaus J, Li D, Feederle R, Maretzky T, Swendemann S, Falck-Pedersen E, McIlwain DR, Mak TW, Salmon JE, Lichtenthaler SF, Blobel CP. J Biol Chem. 2020 Mar 27;295(13):4350-4358. doi: 10.1074/jbc.RA119.011136. Epub 2020 Nov 13. PMID: 33506789

January 1-15, 2021

The anti-tumor effects of cetuximab in combination with VTX-2337 are T cell dependent.

Cheng Y, Borcherding N, Ogunsakin A, Lemke-Miltner CD, Gibson-Corley KN, Rajan A, Choi AB, Wongpattaraworakul W, Chan CHF, Salem AK, Weiner GJ, Simons AL. Sci Rep. 2021 Jan 15;11(1):1535. doi: 10.1038/s41598-020-80957-z. PMID: 33452311

Divergent immune landscapes of primary and syngeneic Kras-driven mouse tumor models. Gutierrez WR, Scherer A, McGivney GR, Brockman QR, Knepper-Adrian V, Laverty EA, Roughton GA, Dodd RD. Sci Rep. 2021 Jan 13;11(1):1098. doi: 10.1038/s41598-020-80216-1. PMID: 33441747 Free PMC article.

Successful Multimodal Measures Preventing COVID-19 Outbreaks Without Universal Frequent Testing within Long-Term Care Units in the Midwestern Veterans Health Care Network. Goto M, Ueckert N, Meiches R, Perencevich E. Infect Control Hosp Epidemiol. 2021 Jan 11:1-7. doi: 10.1017/ice.2020.1419. Online ahead of print. PMID: 33427153

A New Prognostic Model in Patients with Advanced Urothelial Carcinoma Treated with First-line Immune Checkpoint Inhibitors. Khaki AR, Li A, Diamantopoulos LN, Miller NJ, Carril-Ajuria L, Castellano D, De Kouchkovsky I, Koshkin V, Park J, Alva A, Bilen MA, Stewart T, Santos V, Agarwal N, Jain J, Zakharia Y, Morales-Barrera R, Devitt M, Nelson A, Hoimes CJ, Shreck E, Gartrell BA, Sankin A, Tripathi A, Zakopoulou R, Bamias A, Rodriguez-Vida A, Drakaki A, Liu S, Kumar V, Lythgoe MP, Pinato DJ, Murgic J, Fröbe A, Joshi M, Isaacsson Velho P, Hahn N, Alonso Buznego L, Duran I, Moses M, Barata P, Galsky MD, Sonpavde G, Yu EY, Shankaran V, Lyman GH, Grivas P. Eur Urol Oncol. 2021 Jan 7:S2588-9311(20)30214-5. doi: 10.1016/j.euo.2020.12.006. Online ahead of print. PMID: 33423945

Comparative Effectiveness and Safety of Direct Oral Anticoagulants in Obese Patients with Atrial Fibrillation.  Briasoulis A, Mentias A, Mazur A, Alvarez P, Leira EC, Vaughan Sarrazin MS. Cardiovasc Drugs Ther. 2021 Jan 6. doi: 10.1007/s10557-020-07126-2. Online ahead of print. PMID: 33404923

Combination therapies for MPNSTs targeting RABL6A-RB1 signaling.  Kohlmeyer JL, Gordon DJ, Tanas MR, Dodd RD, Monga V, Darbro BW, Quelle DE. Oncotarget. 2021 Jan 5;12(1):10-14. doi: 10.18632/oncotarget.27862. eCollection 2021 Jan 5. PMID: 33456709 Free PMC article.

A Novel Triphenylphosphonium Carrier to Target Mitochondria without Uncoupling Oxidative Phosphorylation. Kulkarni CA, Fink BD, Gibbs BE, Chheda PR, Wu M, Sivitz WI, Kerns RJ. J Med Chem. 2021 Jan 14;64(1):662-676. doi: 10.1021/acs.jmedchem.0c01671. Epub 2021 Jan 4. PMID: 33395531

Maintaining Mobility in a Patient Who Is Pregnant and Has COVID-19 Requiring Extracorporeal Membrane Oxygenation: A Case Report.  Mark A, Crumley JP, Rudolph KL, Doerschug K, Krupp A. Phys Ther. 2021 Jan 4;101(1):pzaa189. doi: 10.1093/ptj/pzaa189. PMID: 33395476 Free PMC article.

Temporal Relationship Between Visual Field, Retinal and Microvascular Pathology Following 125I-Plaque Brachytherapy for Uveal Melanoma. Tamplin MR, Deng W, Garvin MK, Binkley EM, Hyer DE, Buatti JM, Ledolter J, Boldt HC, Kardon RH, Grumbach IM. Invest Ophthalmol Vis Sci. 2021 Jan 4;62(1):3. doi: 10.1167/iovs.62.1.3. PMID: 33393969

Racial disparities in survival outcomes following pediatric in-hospital cardiac arrest. Haskell SE, Girotra S, Zhou Y, Zimmerman MB, Del Rios M, Merchant RM, Atkins DL. Resuscitation. 2021 Jan 2;159:117-125. doi: 10.1016/j.resuscitation.2020.12.018. Online ahead of print. PMID: 33400929

Brown adipose tissue is associated with cardiometabolic health.  Becher T, Palanisamy S, Kramer DJ, Eljalby M, Marx SJ, Wibmer AG, Butler SD, Jiang CS, Vaughan R, Schöder H, Mark A, Cohen P. Nat Med. 2021 Jan;27(1):58-65. doi: 10.1038/s41591-020-1126-7. Epub 2021 Jan 4. PMID: 33398160

Expansion of Transcatheter Aortic Valve Replacement in the United States: Expansion of TAVR in US.  Mentias A, Sarrazin MV, Desai M, Kapadia S, Cram P, Girotra S. Am Heart J. 2020 Dec 31:S0002-8703(20)30427-0. doi: 10.1016/j.ahj.2020.12.018. Online ahead of print. PMID: 33388288

Obesity diminishes response to PD-1-based immunotherapies in renal cancer. Boi SK, Orlandella RM, Gibson JT, Turbitt WJ, Wald G, Thomas L, Buchta Rosean C, Norris KE, Bing M, Bertrand L, Gross BP, Makkouk A, Starenki D, Farag KI, Sorge RE, Brown JA, Gordetsky J, Yasin H, Garje R, Nandagopal L, Weiner GJ, Lubaroff DM, Arend RC, Li P, Zakharia Y, Yang E, Salem AK, Nepple K, Marquez-Lago TT, Norian LA. J Immunother Cancer. 2020 Dec;8(2):e000725. doi: 10.1136/jitc-2020-000725. PMID: 33427691 Free PMC article.