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Paul Ranum


paul-ranum@uiowa.edu
Mentor: Richard Smith, M.D.
Lab Room: 5270 CBRB
Lab Phone: 319-335-6623

Identification and characterization of genetic elements contributing to non-syndromic hearing loss

Shibata SB, Yoshimura H, Ranum PT, Goodwin AT, Smith RJH. Intravenous rAAV2/9 injection for murine cochlear gene delivery. Sci Rep. 2017 Aug 29;7(1):9609. doi:10.1038/s41598-017-09805-x. PubMed PMID: 28852025; PubMed Central PMCID:PMC5575199.

Smith RJH, Ranum PT. Nonsyndromic Hearing Loss and Deafness, DFNA3. 1998 Sep 28 [updated 2016 Dec 22]. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Mefford HC, Stephens K, Amemiya A, Ledbetter N, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2017. Available from http://www.ncbi.nlm.nih.gov/books/NBK1536/PubMed PMID: 20301708.

Shibata SB, Ranum PT, Moteki H, Pan B, Goodwin AT, Gooman SS, Abbas PJ, Holt, JR and Smith JH. RNA interference prevents autosomal dominant hearing loss. Am J Human Genetics, accepted, 2016.

Sloan-Heggen CM, Bierer AO, Shearer AE, Kolbe DL, Nishimura CJ, Frees KL, Ephraim SS, Shibata SB, Booth KT, Campbell CA, Ranum PT, Weaver AE, Black-Ziegelbein EA, Wang D, Azaiez H, Smith RJ. Comprehensive genetic testing in the clinical evaluation of 1119 patients with hearing loss. Hum Genet. 2016 Apr;135(4):441-50. doi: 10.1007/s00439-016-1648-8. Epub 2016 Mar 11. PubMed PMID:26969326; PubMed Central PMCID: PMC4796320.

Azaiez H, Decker AR, Booth KT, Simpson AC, Shearer AE, Huygen PL, Bu F, Hildebrand MS, Ranum PT, Shibata SB, Turner A, Zhang Y, Kimberling WJ, Cornell RA, Smith RJ. HOMER2, a stereociliary scaffolding protein, is essential for normal hearing in humans and mice. PLoS Genet. 2015 Mar 27;11(3):e1005137. doi:10.1371/journal.pgen.1005137. eCollection 2015 Mar. PubMed PMID: 25816005; PubMed Central PMCID: PMC4376867.

Smith RJH, Ranum PT, Van Camp G. Nonsyndromic Hearing Loss and Deafness, DFNA3. 1998 Sep 28 [updated 2014 Jun 12]. In: Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, Bird TD, Fong CT, Mefford HC, Smith RJH, Stephens K, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2016. Available from http://www.ncbi.nlm.nih.gov/books/NBK1536/PubMed PMID: 20301708.