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Nate Mullin, M5G

nathaniel-mullin@uiowa.edu

 

MSTP Learning Community:  McCowen

MSTP Entry Date:  June 4, 2018

PhD Program:

Genetics

Mentors:

Rob Mullins, PhD

Budd Tucker, PhD

Graduate Profile Lab Website

Committees:

2019 (Fall) - Keystone Liaison Committee Member

2020-2022 - MSTP Admissions Committee

2020-2022 - MSTP Executive Committee

Awards:

2018 - Edward Heath Award (U of I Foundation Award), Medical Student Research Conference, Sept 14

2020-2022 - Appointed to Genetics Program T32

2021 - 1st Place Poster Presentation at the Annual Genetics Retreat

2021 - Retina Research Foundation / Joseph M. and Eula C. Lawrence Travel Grant to the ARVO Annual Meeting

2022 - Fall Graduate College Post-Comp Fellowship

2022 - Carver College of Medicine Trainee Scholar Award

Individual Funding Awards:

08/05/2022 - 08/04/2024
F30 EY 034009 - (National Eye Institute)
Pathogenesis of Mitochondrial Retina Disease

Teaching:

2019 Fall - M1 Foundations Tutor

2019 Fall - M1 MOHD I Tutor

2021 SUMR - Facilitated two sessions of Clinical Skills Session (patient-provider encounters) to SUMR students

2021 Fall - MOHD IV tutoring

2021 Fall - Keystone Tutor

2022 Fall - MOHD IV Tutor

Mentorship:

2021 & 2022 - SUMR Program - McCowen Community Student Advisor

Education:

2016 - BA, Biology, Philosophy - Case Western Reserve University

Publications:

ORCiD:  0000-0003-4320-2852

Thompson JR, Worthington KS, Green BJ, Mullin NK, Jiao C, Kaalberg EE, Wiley LA, Han IC, Russell SR, Sohn EH, Guymon CA, Mullins RF, Stone EM, Tucker BA. Two-photon polymerized poly(caprolactone) retinal cell delivery scaffolds and their systemic and retinal biocompatibility. Acta Biomater. 2019 Aug;94:204-218. doi: 10.1016/j.actbio.2019.04.057. Epub 2019 May 3. PubMed PMID: 31055121; PubMed Central PMCID: PMC6659122.

Voigt AP, Mulfaul K, Mullin NK, Flamme-Wiese MJ, Giacalone JC, Stone EM, Tucker BA, Scheetz TE, Mullins RF. Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24100-24107. doi: 10.1073/pnas.1914143116. Epub 2019 Nov 11. PubMed PMID: 31712411; PubMed Central PMCID: PMC6883845.

Mullin NK, Voigt AP, Cooke JA, Bohrer LR, Burnight ER, Stone EM, Mullins RF, Tucker BA. Patient derived stem cells for discovery and validation of novel pathogenic variants in inherited retinal disease. Prog Retin Eye Res. 2020 Oct 29;:100918. doi: 10.1016/j.preteyeres.2020.100918. [Epub ahead of print] Review. PubMed PMID: 33130253; NIHMSID:NIHMS1659236.

Voigt AP, Mullin NK, Stone EM, Tucker BA, Scheetz TE, Mullins RF. Single-cell RNA sequencing in vision research: Insights into human retinal health and disease. Prog Retin Eye Res. 2021 Jul;83:100934. doi: 10.1016/j.preteyeres.2020.100934. Epub 2020 Dec 28. Review. PubMed PMID: 33383180; PubMed Central PMCID: PMC8236499.

Voigt AP, Mullin NK, Whitmore SS, DeLuca AP, Burnight ER, Liu X, Tucker BA, Scheetz TE, Stone EM, Mullins RF. Human photoreceptor cells from different macular subregions have distinct transcriptional profiles. Hum Mol Genet. 2021 May 20;. doi: 10.1093/hmg/ddab140. [Epub ahead of print] PubMed PMID: 34014299; PubMed Central PMCID: PMC8330894.

Mullin NK, Anfinson KR, Riker MJ, Wieland KL, Tatro NJ, Scheetz TE, Mullins RF, Stone EM, Tucker BA. Sensitive quantification of m.3243A>G mutational proportion in non-retinal tissues and its relationship with visual symptoms. Hum Mol Genet. 2021 Sep 30;. doi: 10.1093/hmg/ddab289. [Epub ahead of print] PubMed PMID: 34590675.

Mulfaul K, Mullin NK, Giacalone JC, Voigt AP, DeVore M, Stone EM, Tucker BA, Mullins RF. Local Factor H production by human choroidal endothelial cells mitigates complement deposition: implications for macular degeneration. J Pathol. 2022 Jan 17. doi: 10.1002/path.5867. Epub ahead of print. PMID: 35038170.

Voigt AP, Mullin NK, Mulfaul K, Lozano LP, Wiley LA, Flamme-Wiese MJ, Boese EA, Han IC, Scheetz TE, Stone EM, Tucker BA, Mullins RF. Choroidal Endothelial and Macrophage Gene Expression in Atrophic and Neovascular Macular Degeneration. Hum Mol Genet. 2022 Feb 19:ddac043. doi: 10.1093/hmg/ddac043. Epub ahead of print. PMID: 35181781.